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  1. Book ; Conference proceedings: The 2010 Sixth International Symposium on Cough

    Widdicombe, John G.

    [London, on June 24 to 26, 2010]

    (Pulmonary pharmacology & therapeutics ; 24,3 = Special issue)

    2011  

    Event/congress International Symposium on Cough (6, 2010, London)
    Author's details guest ed.: John Widdicombe
    Series title Pulmonary pharmacology & therapeutics ; 24,3 = Special issue
    Collection
    Language English
    Size S. 261 - 352 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT016863333
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 2389 -24- not available for loan Zeitschriften-Lesesaal

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  2. Book ; Online: Seawater carbonate chemistry and Celleporella hyalina biological processes during experiments, 2011, supplementary data to: Pistevos, Jennifer C A; Calosi, Piero; Widdicombe, Stephen; Bishop, John D D (2011): Will variation among genetic individuals influence species responses to global climate change?. Oikos, 120(5), 675-689

    Pistevos, Jennifer C A / Bishop, John D D / Calosi, Piero / Widdicombe, Stephen

    2011  

    Abstract: Increased anthropogenic CO2 emissions in the last two centuries have lead to rising sea surface temperature and falling ocean pH, and it is predicted that current global trends will worsen over the next few decades. There is limited understanding of how ... ...

    Abstract Increased anthropogenic CO2 emissions in the last two centuries have lead to rising sea surface temperature and falling ocean pH, and it is predicted that current global trends will worsen over the next few decades. There is limited understanding of how genetic variation among individuals will influence the responses of populations and species to these changes. A microcosm system was set up to study the effects of predicted temperature and CO2 levels on the bryozoan Celleporella hyalina. In this marine species, colonies grow by the addition of male, female and feeding modular individuals (zooids) and can be physically subdivided to produce a clone of genetically identical colonies. We studied colony growth rate (the addition of zooids), reproductive investment (the ratio of sexual to feeding zooids) and sex ratio (male to female zooids) in four genetically distinct clonal lines. There was a significant effect of clone on growth rate, reproductive investment and sex ratio, with clones showing contrasting responses to the various temperature and pH combinations. Overall, decreasing pH and increasing temperature caused reduction of growth, and eventual cessation of growth was often observed at the highest temperature, especially during the latter half of the 15-day trials. Reproductive investment increased with increasing temperature and decreasing pH, varying more widely with temperature at the lowest pH. The increased production of males, a general stress response of the bryozoan, was seen upon exposure to reduced pH, but was not expressed at the highest temperature tested, presumably due to the frequent cessation of growth. Further to the significant effect of pH on the measured whole-colony parameters, observation by scanning electron microscopy revealed surface pitting of the calcified exoskeleton in colonies that were exposed to increased acidity. Studying ecologically relevant processes of growth and reproduction, we demonstrate the existence of relevant levels of variation among genetic individuals which may enable future adaptation via non-mutational natural selection to falling pH and rising temperature.
    Language English
    Dates of publication 2011-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1111/j.1600-0706.2010.19470.x
    DOI 10.1594/PANGAEA.758700
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Article ; Online: Wearable Transmitter Coil Design for Inductive Wireless Power Transfer to Implantable Devices.

    Tai, Yi-De / Widdicombe, Bryce / Unnithan, Ranjith R / Grayden, David B / John, Sam E

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2023  Volume 2023, Page(s) 1–4

    Abstract: Wireless endovascular sensors and stimulators are emerging biomedical technologies for applications such as endovascular pressure monitoring, hyperthermia, and neural stimulations. Recently, coil-shaped stents have been proposed for inductive power ... ...

    Abstract Wireless endovascular sensors and stimulators are emerging biomedical technologies for applications such as endovascular pressure monitoring, hyperthermia, and neural stimulations. Recently, coil-shaped stents have been proposed for inductive power transfer to endovascular devices using the stent as a receiver. However, less work has been done on the external transmitter components, so the maximum power transferable remains unknown. In this work, we design and evaluate a wearable transmitter coil that allows 50 mW power transfer in simulation.Clinical Relevance-This allows more accurate measurements and precise control of endovascular devices.
    MeSH term(s) Wireless Technology ; Electric Power Supplies ; Computer Simulation ; Stents ; Wearable Electronic Devices
    Language English
    Publishing date 2023-12-11
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC40787.2023.10340600
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Conference proceedings: Cough: methods and mechanisms

    Widdicombe, John G.

    on October 11 - 12, 1996 an international symposium was held ... at the National Heart and Lung Institute, London

    (Pulmonary pharmacology ; 9,5/6 : Special issue)

    1996  

    Institution National Heart and Lung Institute
    Author's details John Widdicombe, [guest ed.]
    Series title Pulmonary pharmacology ; 9,5/6 : Special issue
    Collection
    Keywords Cough / congresses ; Antitussive Agents / congresses
    Language English
    Size S. 259 - 392 : graph. Darst.
    Publisher Academic Pr
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT007631431
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 2389 -9- not available for loan Zeitschriften-Lesesaal

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  5. Article ; Online ; Conference proceedings: Basic poster discussion: summary.

    Widdicombe, John

    Pulmonary pharmacology & therapeutics

    2011  Volume 24, Issue 3, Page(s) 339–340

    Abstract: Twelve posters were presented in the section on Basic Research. They were discussed in a session chaired by Paul Davenport (Gainesville, US) and Marian Kollarik (Boston, US), with each poster presenter first briefly describing his/her poster. ...

    Abstract Twelve posters were presented in the section on Basic Research. They were discussed in a session chaired by Paul Davenport (Gainesville, US) and Marian Kollarik (Boston, US), with each poster presenter first briefly describing his/her poster.
    MeSH term(s) Animals ; Cells, Cultured ; Chronic Disease ; Cough/physiopathology ; Humans ; Reflex ; Transient Receptor Potential Channels/drug effects ; Transient Receptor Potential Channels/metabolism
    Chemical Substances Transient Receptor Potential Channels
    Language English
    Publishing date 2011-06
    Publishing country England
    Document type Congresses
    ZDB-ID 1399707-5
    ISSN 1522-9629 ; 1094-5539
    ISSN (online) 1522-9629
    ISSN 1094-5539
    DOI 10.1016/j.pupt.2011.01.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2389: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Book: The cough reflex

    Widdicombe, John G.

    two symposia held in Martin, Slovakia, CSSR, 10 -12 Sept. 1986

    (Clinical respiratory physiology : Suppl. ; 10)

    1987  

    Title variant Nerves and mediators in bronchial asthma
    Author's details ed. by J. G. Widdicombe
    Series title Clinical respiratory physiology : Suppl. ; 10
    Clinical respiratory physiology/Supplement
    Clinical respiratory physiology ; Suppl.
    Collection Clinical respiratory physiology/Supplement
    Clinical respiratory physiology ; Suppl.
    Keywords Asthma / congresses ; Cough / congresses
    Size 137s S. : graph. Darst.
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT003128335
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 816 -Suppl.10- verfügbar in Königswinter Königswinter

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  7. Book: Respiratory physiology

    Widdicombe, John G. / Davies, Andrew

    (Physiological principles in medicine)

    1991  

    Author's details John Widdicombe ; Andrew Davies
    Series title Physiological principles in medicine
    Keywords Respiration ; Respiratory System / physiology
    Size VII, 132 S. : Ill., graph. Darst.
    Edition 2. ed.
    Publisher Arnold
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT003974376
    ISBN 0-340-55253-0 ; 978-0-340-55253-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1992 A 444 order for loan Magazin

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  8. Article ; Online: Lung afferent activity: implications for respiratory sensation.

    Widdicombe, John

    Respiratory physiology & neurobiology

    2009  Volume 167, Issue 1, Page(s) 2–8

    Abstract: Stimuli within the lung can cause the sensations of pain, ache, irritation and urge-to-cough. In general these are abolished or inhibited by vagal section or vagal anaesthesia, or local anaesthesia within the airways. They are present in patients with ... ...

    Abstract Stimuli within the lung can cause the sensations of pain, ache, irritation and urge-to-cough. In general these are abolished or inhibited by vagal section or vagal anaesthesia, or local anaesthesia within the airways. They are present in patients with functional high cervical spinal cord transaction and after general neuromuscular paralysis. There are at least nine sensors in the bronchopulmonary system, studied almost entirely in animals. It is at present impossible to link any one sensor with any one pattern of sensation. It is reasonable to suppose that urge-to-cough arises from sensors what mediate cough, but there are at least five sensors involved in this reflex, and how they relate to unpleasant sensation is unknown. The problem is that sensation can almost only be studied in humans, and the vagal neural mechanisms almost only in other species. Vagal sensors can also ameliorate the sensation of air hunger, and this is probably due to the action of slowly adapting pulmonary stretch receptors (SARs). The same sensors may give rise to the awareness of lung volume and its changes. Many sensors in the lungs can be sensitized or desensitized by natural or imposed conditions, and this could underlie the sensitization and desensitization of dyspnoeic sensations that have been described.
    MeSH term(s) Afferent Pathways/physiology ; Animals ; Cough/physiopathology ; Humans ; Lung/innervation ; Reflex/physiology ; Respiratory Mechanics/physiology ; Sensation/physiology
    Language English
    Publishing date 2009-05-30
    Publishing country Netherlands
    Document type Editorial ; Review
    ZDB-ID 2077867-3
    ISSN 1878-1519 ; 1569-9048
    ISSN (online) 1878-1519
    ISSN 1569-9048
    DOI 10.1016/j.resp.2008.09.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 519: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  9. Book: Respiratory physiology / 3

    Widdicombe, John G.

    (International review of physiology ; 23)

    1981  

    Series title International review of physiology ; 23
    Respiratory physiology
    Collection Respiratory physiology
    Keywords Atmung ; Physiologie
    Subject Humanphysiologie ; Mensch ; Körperfunktion ; Respiration
    Language English
    Publisher Univ. Park Pr
    Publishing place Baltimore
    Document type Book
    HBZ-ID HT002085278
    ISBN 0-8391-1604-7 ; 978-0-8391-1604-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1977 A 2175 -3- order for loan Magazin

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  10. Book: RESPIRATORY PHARMACOLOGY

    Widdicombe, John G.

    (INTERNATIONAL ENCYCLOPEDIA OF PHARMACOLOGY AND THERAPEUTICS ; 104 ; PHARMACOLOGY & THERAPEUTICS : SUPPL. ; [2])

    1981  

    Author's details SECT. ED.: J. WIDDICOMBE
    Series title INTERNATIONAL ENCYCLOPEDIA OF PHARMACOLOGY AND THERAPEUTICS ; 104
    PHARMACOLOGY & THERAPEUTICS : SUPPL. ; [2]
    Pharmacology & therapeutics
    International encyclopedia of pharmacology and therapeutics
    PHARMACOLOGY & THERAPEUTICS ; SUPPL.
    Collection Pharmacology & therapeutics
    International encyclopedia of pharmacology and therapeutics
    PHARMACOLOGY & THERAPEUTICS ; SUPPL.
    Keywords RESPIRATORY SYSTEM / DRUG EFFECTS
    Language English
    Size XVI, 765 S.
    Publisher PERGAMON PR
    Publishing place OXFORD U.A.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT002480518
    ISBN 0-08-022673-6 ; 978-0-08-022673-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1967 A 476 -104- order for loan Magazin

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