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  1. Article ; Online: EEG-neurofeedback and psychodynamic psychotherapy in a case of adolescent anhedonia with substance misuse: mood/theta relations.

    Unterrainer, H F / Chen, M J-L / Gruzelier, J H

    International journal of psychophysiology : official journal of the International Organization of Psychophysiology

    2014  Volume 93, Issue 1, Page(s) 84–95

    Abstract: There is substantial evidence confirming the efficacy of neurofeedback with applications in clinical, educational and optimal performance domains. However, a psychodynamically informed NF-approach needs exploration. A male (19 y), college student whose ... ...

    Abstract There is substantial evidence confirming the efficacy of neurofeedback with applications in clinical, educational and optimal performance domains. However, a psychodynamically informed NF-approach needs exploration. A male (19 y), college student whose first year was being seriously compromised after severe, 18-month, polydrug misuse, was treated with 11 sessions including a 2-month follow-up of neurofeedback combined with short-term psychodynamic psychotherapy. Pre/post-treatment and follow-up assessment with the Brief Psychiatric Rating Scale (BPRS) and the Montgomery-Asberg Depression Rating Scale confirmed that levels of psychopathology dropped almost to zero. Correlational evidence disclosed that SMR/theta training was positively associated with reduction in psychopathological ratings, largely due to theta amplitude reduction; the strongest relation being with reduced BPRS activation. Alpha/theta training was not correlated with clinical improvement. The combined treatment was found to be highly effective with the student who learned to deal with feelings of anhedonia and alienation. There was no relapse during the follow-up phase. Further research is recommended.
    MeSH term(s) Affect/physiology ; Anhedonia/physiology ; Electroencephalography/methods ; Humans ; Male ; Neurofeedback/methods ; Personality Tests ; Psychiatric Status Rating Scales ; Psychotherapy, Brief ; Psychotherapy, Psychodynamic/methods ; Substance-Related Disorders/psychology ; Substance-Related Disorders/rehabilitation ; Theta Rhythm/physiology ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2014-07
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 605645-3
    ISSN 1872-7697 ; 0167-8760
    ISSN (online) 1872-7697
    ISSN 0167-8760
    DOI 10.1016/j.ijpsycho.2013.03.011
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  2. Article ; Online: Neurofeedback: introduction to the special issue.

    van Boxtel, Geert J M / Gruzelier, John H

    Biological psychology

    2014  Volume 95, Page(s) 1–3

    MeSH term(s) Brain/physiology ; Humans ; Neurofeedback
    Language English
    Publishing date 2014-01
    Publishing country Netherlands
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 185105-6
    ISSN 1873-6246 ; 0301-0511
    ISSN (online) 1873-6246
    ISSN 0301-0511
    DOI 10.1016/j.biopsycho.2013.11.011
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  3. Article: EEG-Neurofeedback in psychodynamic treatment of substance dependence.

    Unterrainer, Human F / Lewis, Andrew J / Gruzelier, John H

    Frontiers in psychology

    2013  Volume 4, Page(s) 692

    Language English
    Publishing date 2013-10-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2013.00692
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  4. Article: The role of psychological intervention in modulating aspects of immune function in relation to health and well-being.

    Gruzelier, J H

    International review of neurobiology

    2002  Volume 52, Page(s) 383–417

    MeSH term(s) Animals ; Health ; Humans ; Immune System/immunology ; Immunity/immunology ; Mind-Body Therapies/methods ; Mind-Body Therapies/psychology ; Psychoneuroimmunology/trends
    Language English
    Publishing date 2002-11-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 209876-3
    ISSN 0074-7742
    ISSN 0074-7742
    DOI 10.1016/s0074-7742(02)52017-1
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  5. Article: A review of the impact of hypnosis, relaxation, guided imagery and individual differences on aspects of immunity and health.

    Gruzelier, J H

    Stress (Amsterdam, Netherlands)

    2002  Volume 5, Issue 2, Page(s) 147–163

    Abstract: This review considers psychological interventions involving relaxation and guided imagery targeting immune functions. The review provides evidence of immune control accompanied by reports of enhanced mood and well-being. Three recent investigations of ... ...

    Abstract This review considers psychological interventions involving relaxation and guided imagery targeting immune functions. The review provides evidence of immune control accompanied by reports of enhanced mood and well-being. Three recent investigations of the author and his colleagues with self-hypnosis training incorporating imagery of the immune system are outlined. In two studies, hypnosis buffered the effects of stress on immune functions in medical students at exam time, and the comparison of self-hypnosis with and without immune imagery confirmed advantages to targeted imagery for both immune function and mood, and importantly, fewer winter viral infections. The implications for health were investigated in a third study in patients with virulent and chronic herpes simplex virus-2 HSV-2). Six weeks of training almost halved recurrence, improved mood and reduced levels of clinical depression and anxiety. Immune functions were up-regulated, notably functional natural killer cell activity to HSV-1. Individual differences in hypnotic susceptibility and absorption have typically been found to predict efficacy. New replicable evidence is reviewed of the importance of cognitive activation, a personality difference whose neurophysiological underpinning is consistent with left hemispheric preferential influences over the immune system. Now that the validation of psychological interventions includes advantages for health, this field of enquiry, which has been characterised by modest, small scale, largely preliminary studies, warrants a greater investment in research.
    MeSH term(s) Health ; Humans ; Hypnosis ; Imagery (Psychotherapy) ; Immunity/physiology ; Individuality ; Relaxation Therapy ; Stress, Psychological/immunology ; Stress, Psychological/physiopathology
    Language English
    Publishing date 2002-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1387706-9
    ISSN 1607-8888 ; 1025-3890
    ISSN (online) 1607-8888
    ISSN 1025-3890
    DOI 10.1080/10253890290027877
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  6. Article ; Online: Immediate effects of Alpha/theta and Sensory-Motor Rhythm feedback on music performance.

    Gruzelier, J H / Hirst, L / Holmes, P / Leach, J

    International journal of psychophysiology : official journal of the International Organization of Psychophysiology

    2014  Volume 93, Issue 1, Page(s) 96–104

    Abstract: ... on music. The original report (Egner and Gruzelier, 2003) established a beneficial outcome for elite ... training benefited novice performance only (Gruzelier, Holmes et al., 2014). Here we report a replication ...

    Abstract This is one of a series of investigations comparing two EEG-neurofeedback protocols - Alpha/theta (A/T) and Sensory-Motor Rhythm (SMR) - for performance enhancement in the Arts, here with the focus on music. The original report (Egner and Gruzelier, 2003) established a beneficial outcome for elite conservatoire musicians following A/T training in two investigations. Subsequently this A/T advantage was replicated for both advanced instrumental and novice singing abilities, including improvisation, while SMR training benefited novice performance only (Gruzelier, Holmes et al., 2014). Here we report a replication of the latter study in university instrumentalists who as before were novice singers with one design change - post-training performances were conducted within the tenth final session instead of on a subsequent occasion. As before expert judges rated the domains of Creativity/Musicality, Communication/Presentation and Technique. The proximity to training of the music performances within the last session likely compromised gains from A/T learning, but perhaps reinforced the impact of SMR training efficacy. In support of validation there was evidence of strong within- and across-session A/T learning and positive linear trends for across-session SMR/theta and SMR/beta-2 ratio learning. In support of mediation learning correlated with music performance. The A/T outcome was markedly discrepant from previous studies and should dispel any impression that the hypnogogic state itself is transferred to the performance context. The effects of SMR ratio training are consistent with an impact on lower-order abilities required in novice performance such as sustained attention and memory, and benefiting all three domains of music assessment.
    MeSH term(s) Adult ; Alpha Rhythm/physiology ; Anxiety/prevention & control ; Anxiety/psychology ; Creativity ; Female ; Humans ; Male ; Movement/physiology ; Music/psychology ; Neurofeedback/methods ; Psychomotor Performance/physiology ; Sensation/physiology ; Singing/physiology ; Theta Rhythm/physiology ; Young Adult
    Language English
    Publishing date 2014-07
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605645-3
    ISSN 1872-7697 ; 0167-8760
    ISSN (online) 1872-7697
    ISSN 0167-8760
    DOI 10.1016/j.ijpsycho.2014.03.009
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  7. Article ; Online: Neurofeedback facilitation of implicit motor learning.

    Ros, T / Munneke, M A M / Parkinson, L A / Gruzelier, J H

    Biological psychology

    2014  Volume 95, Page(s) 54–58

    Abstract: Background: Mu rhythm desynchronisation via EEG-neurofeedback (NFB) has been previously been shown to induce durable motor-cortical disinhibition for at least 20 min. It was hypothesised that the presentation of a novel procedural learning task ... ...

    Abstract Background: Mu rhythm desynchronisation via EEG-neurofeedback (NFB) has been previously been shown to induce durable motor-cortical disinhibition for at least 20 min. It was hypothesised that the presentation of a novel procedural learning task immediately after this NFB protocol would boost motor performance.
    Method: The protocol consisted of firstly activating the right primary motor cortex with a single session of Mu (8-12 Hz) suppression via NFB for a total of 30 min. Shortly after, and with their non-dominant (left) hand, subjects (n=10) performed the serial reaction time task (SRTT), which is used to assess reaction time improvement over multiple trials. During another occasion (1 week before/after), the same subjects were tested on a different sequence without prior NFB, as part of a counterbalanced control condition.
    Results: Compared to a "cross-over" condition without NFB, subjects who received NFB immediately prior to SRTT performance exhibited a significantly faster rate of learning, reflected in a greater reduction of reaction times across blocks (p=0.02). This occurred in the absence of explicit awareness of a repeating sequence. Moreover, no significant differences were observed between conditions in error rate or reaction time variability.
    Conclusion: Our results suggest that a single NFB session may be directly used to facilitate the early acquisition of a procedural motor task, and are the first to demonstrate that neurofeedback effects could be exploited immediately after individual training sessions so as to boost behavioural performance and learning.
    MeSH term(s) Adult ; Brain/physiology ; Electroencephalography ; Female ; Humans ; Learning/physiology ; Male ; Middle Aged ; Neurofeedback/methods ; Psychomotor Performance/physiology ; Reaction Time/physiology
    Language English
    Publishing date 2014-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 185105-6
    ISSN 1873-6246 ; 0301-0511
    ISSN (online) 1873-6246
    ISSN 0301-0511
    DOI 10.1016/j.biopsycho.2013.04.013
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  8. Article: Functional neuropsychophysiological asymmetry in schizophrenia: a review and reorientation.

    Gruzelier, J H

    Schizophrenia bulletin

    1999  Volume 25, Issue 1, Page(s) 91–120

    Abstract: In reviewing the neuropsychophysiological evidence of functional asymmetry it is proposed that schizophrenia is characterized by a greater dispersion of leftward and rightward asymmetries. The two extremes are represented by active (left greater than ... ...

    Abstract In reviewing the neuropsychophysiological evidence of functional asymmetry it is proposed that schizophrenia is characterized by a greater dispersion of leftward and rightward asymmetries. The two extremes are represented by active (left greater than right) and withdrawn (right greater than left) syndromes, as is the case with psychometric schizotypy. Syndrome-asymmetry relations extended beyond fronto-temporal systems to include posterior activity, infracortical motoneuron excitability, and individual differences in interhemispheric connectivity and directional biases. Central to these are lateral imbalances in thalamo-cortical and callosal arousal systems, while centrality to schizophrenia follows evidence of reversals in asymmetry with changes in symptom profile, clinical recovery, and neuroleptic treatment. Affinities are found in intact animals from challenge-induced turning tendencies representing coordinated activity of attentional, motor, and reinforcement systems. In both patients and animals, neuroleptics have reciprocal interhemispheric effects, with a bidirectionality that depends on syndrome or endogenous turning preference. Bidirectionality implicates nonspecific thalamic system (NSTS) and not limbic projections. It is proposed that the asymmetries arise from endogenous influences of genes, hormones, and early experience including stressors on NSTS asymmetry, and these underpin approach/withdrawal behavior that is manifested in temperament, personality, and clinical syndrome, and which precedes language development.
    MeSH term(s) Animals ; Antipsychotic Agents/pharmacology ; Brain/pathology ; Corpus Callosum ; Functional Laterality/physiology ; Humans ; Motor Neurons/physiology ; Personality ; Schizophrenia/physiopathology ; Thalamus/drug effects ; Thalamus/pathology
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 1999
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 439173-1
    ISSN 1745-1701 ; 0586-7614
    ISSN (online) 1745-1701
    ISSN 0586-7614
    DOI 10.1093/oxfordjournals.schbul.a033370
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  9. Article: Short-term Beneficial Effects of 12 Sessions of Neurofeedback on Avoidant Personality Accentuation in the Treatment of Alcohol Use Disorder.

    Dalkner, Nina / Unterrainer, Human F / Wood, Guilherme / Skliris, Dimitris / Holasek, Sandra J / Gruzelier, John H / Neuper, Christa

    Frontiers in psychology

    2017  Volume 8, Page(s) 1688

    Abstract: This study evaluated the effects of alpha/theta neurofeedback on Clinical Personality Accentuations in individuals with alcohol use disorder. Twenty-five males were investigated using a pre-test/post-test design with a waiting-list control group. ... ...

    Abstract This study evaluated the effects of alpha/theta neurofeedback on Clinical Personality Accentuations in individuals with alcohol use disorder. Twenty-five males were investigated using a pre-test/post-test design with a waiting-list control group. Participants were randomly assigned either to an experimental group (
    Language English
    Publishing date 2017-09-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2017.01688
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  10. Article: New advances in EEG and cognition.

    Gruzelier, J H

    International journal of psychophysiology : official journal of the International Organization of Psychophysiology

    1996  Volume 24, Issue 1-2, Page(s) 1–5

    MeSH term(s) Alpha Rhythm ; Cognition/physiology ; Cortical Synchronization ; Electroencephalography ; Humans
    Language English
    Publishing date 1996-11
    Publishing country Netherlands
    Document type Editorial ; Review
    ZDB-ID 605645-3
    ISSN 1872-7697 ; 0167-8760
    ISSN (online) 1872-7697
    ISSN 0167-8760
    DOI 10.1016/s0167-8760(96)00069-4
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