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Book ; Thesis: Quantifizierung der Irisfarbe

Schönfeld, Thomas

2002

Author's details	vorgelegt von Thomas Schönfeld
Language	German
Size	72 S., Ill., graph. Darst., 21 cm
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Würzburg, Univ., Diss., 2003
HBZ-ID	HT013681256
Database	Catalogue ZB MED Medicine, Health

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Article ; Online: Assessing the one-month mortality impact of civilian-setting prehospital transfusion: A systematic review and meta-analysis.

Schoenfeld, David W / Rosen, Carlo L / Harris, Tim / Thomas, Stephen H

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

2024

Abstract: Background: Based on convincing evidence for outcomes improvement in the military setting, the past decade has seen evaluation of prehospital transfusion (PHT) in the civilian emergency medical services (EMS) setting. Evidence synthesis has been ... ...

Abstract	Background: Based on convincing evidence for outcomes improvement in the military setting, the past decade has seen evaluation of prehospital transfusion (PHT) in the civilian emergency medical services (EMS) setting. Evidence synthesis has been challenging, due to study design variation with respect to both exposure (type of blood product administered) and outcome (endpoint definitions and timing). The goal of the current meta-analysis was to execute an overarching assessment of all civilian-arena randomized controlled trial (RCT) evidence focusing on administration of blood products compared to control of no blood products. Method: The review structure followed the Cochrane group's Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA). Using the Transfusion Evidence Library (transfusionevidencelibrary.com), the multidatabase (e.g. PubMed, EMBASE) Harvard On-Line Library Information System (HOLLIS), and GoogleScholar, we accessed many databases and gray literature sources. RCTs of PHT in the civilian setting with a comparison group receiving no blood products with 1-month mortality outcomes were identified. Results: In assessing a single patient-centered endpoint-1-month mortality-we calculated an overall risk ratio (RR) estimate. Analysis of three RCTs yielded a model with acceptable heterogeneity (I Conclusions: Current evidence does not demonstrate 1-month mortality benefit of civilian-setting PHT. This should give pause to EMS systems considering adoption of civilian-setting PHT programs. Further studies should not only focus on which formulations of blood products might improve outcomes but also focus on which patients are most likely to benefit from any form of civilian-setting PHT.
Language	English
Publishing date	2024-03-22
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1329813-6
ISSN	1553-2712 ; 1069-6563
ISSN (online)	1553-2712
ISSN	1069-6563
DOI	10.1111/acem.14882
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 4479: Show issues

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Article: Perceived Health Benefits in Vestibular Schwannoma Patients with Long-Term Postoperative Headache: Insights from Personality Traits and Pain Coping-A Cross-Sectional Study.

Thomas, Mareike / Führes, Hannah / Scheer, Maximilian / Rampp, Stefan / Strauss, Christian / Schönfeld, Robby / Leplow, Bernd

Journal of personalized medicine

2024 Volume 14, Issue 1

Abstract: Postoperative headaches (POHs) following retrosigmoid microsurgery for vestibular schwannoma (VS) can significantly impact patients' perceived health benefits (PHBs). In this cross-sectional observational study, 101 VS patients were investigated. For the ...

Abstract	Postoperative headaches (POHs) following retrosigmoid microsurgery for vestibular schwannoma (VS) can significantly impact patients' perceived health benefits (PHBs). In this cross-sectional observational study, 101 VS patients were investigated. For the assessment of pain, the Rostock Headache Compendium (RoKoKo) and the German pain processing questionnaire (FESV) were used. The perceived health benefits (PHBs) were assessed by the Glasgow Benefit Inventory (GBI) and Big Five personality traits were measured using the Ten-Item Personality Inventory (TIPI-G). We showed that 55% of the participants experienced POHs, leading to a marked reduction in overall PHBs compared to those without POHs. The correlation analysis revealed an association between decreased PHBs and elevated levels of pain-related helplessness, depression, anxiety, and anger. Positive correlations were identified between PHBs and action-planning competence, cognitive restructuring, and the experience of competence. Low emotional stability and openness yielded associations with pain-related psychological impairment. Hearing loss and facial paresis did not exert a significant impact on PHBs. The study highlights the influence of pain-related coping strategies on PHBs in long-term POH patients. Thus, coping mechanisms and personality traits should be assessed even before surgery for post-surgery pain prevention. The limitations of this study include a relatively small sample size, potential biases introduced by the overrepresentation of female patients, and the use of an online survey methodology. In conclusion, this research highlights that the interplay between headaches, PHBs, and psychological factors is also relevant in VS patients undergoing microsurgery. Short-term psychological interventions should therefore be taken into account to improve post-surgery adaptive coping strategies.
Language	English
Publishing date	2024-01-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm14010075
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Psychological factors and long-term tinnitus handicap in vestibular schwannoma patients after retrosigmoid microsurgery - a cross-sectional study.

Thomas, M / Scheer, M / Rampp, S / Strauss, C / Schönfeld, R / Leplow, B

International journal of audiology

2024 , Page(s) 1–8

Abstract: Objective: This study aimed to investigate the connection between psychological factors and postoperative tinnitus in vestibular schwannoma (VS) patients following retrosigmoid microsurgery.: Design: Cross-sectional study.: Study sample: Ninety- ... ...

Abstract	Objective: This study aimed to investigate the connection between psychological factors and postoperative tinnitus in vestibular schwannoma (VS) patients following retrosigmoid microsurgery. Design: Cross-sectional study. Study sample: Ninety-three VS patients participated, completing questionnaires on demographics, tinnitus severity (THI-12), personality traits (TIPI-G), dizziness impact (DHI), perceived health benefits (GBI), somatisation tendencies (SOMS-2), and psychological distress (HADS-D). Our analysis involved Mann-Whitney Results: Most participants reported postoperative tinnitus (77/93), with 41 experiencing it preoperatively. Emotional stability correlated negatively with tinnitus presence, while tinnitus severity was associated with emotional distress. Preoperative somatisation tendencies were also positively linked to tinnitus severity. Postoperative Tinnitus was further linked to reduced perceived health benefits and increased anxiety and depression levels. Notably, age and gender showed no significant associations. Conclusion: This study uncovers the interplay between postoperative tinnitus and psychological factors in VS patients, highlighting emotional and cognitive dimensions. Tailored psychological interventions addressing tinnitus's psychosomatic impact may enhance patients quality of life.
Language	English
Publishing date	2024-04-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2073098-6
ISSN	1708-8186 ; 1499-2027
ISSN (online)	1708-8186
ISSN	1499-2027
DOI	10.1080/14992027.2024.2339351
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 549: Show issues

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Article: Premorbid Psychological Factors Associated with Long-Term Postoperative Headache after Microsurgery in Vestibular Schwannoma-A Retrospective Pilot Study.

Thomas, Mareike / Rampp, Stefan / Scheer, Maximilian / Strauss, Christian / Prell, Julian / Schönfeld, Robby / Leplow, Bernd

Brain sciences

2023 Volume 13, Issue 8

Abstract: Associations between premorbid psychological factors and postoperative headache (POH) after microsurgical treatment via the retrosigmoid approach for vestibular schwannoma (VS) were investigated in this retrospective single-center study. A total of 101 ... ...

Abstract	Associations between premorbid psychological factors and postoperative headache (POH) after microsurgical treatment via the retrosigmoid approach for vestibular schwannoma (VS) were investigated in this retrospective single-center study. A total of 101 VS patients completed the Rostock headache questionnaire (RoKoKo), the hospital and anxiety scale (HADS-D), and the screening for somatoform disorders (SOMS-2), all of which were used as short self-assessed questionnaires. Fifty-four patients with POH were compared with 47 non-POH patients in terms of premorbid psychological factors, somatization tendencies, and psychological burden using the chi
Language	English
Publishing date	2023-08-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2651993-8
ISSN	2076-3425
ISSN	2076-3425
DOI	10.3390/brainsci13081171
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Aus dem Hype wird langsam Ernst

Schönfeld, Thomas

Die Bank : Zeitschrift für Bankpolitik und Praxis , No. 8 , p. 26-29

2017 , Issue 8, Page(s) 26–29

Author's details	Dr. Thomas Schönfeld
Language	German
Publisher	Bank-Verlag
Publishing place	Köln
Document type	Article
ZDB-ID	131636-9
ISSN	0342-3182
Database	ECONomics Information System

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Article ; Online: Longitudinal Assessment of Acute Concussion Outcomes Through SMS Text (ConText Study).

Schoenfeld, Robert / Drendel, Amy / Ahamed, Sheikh Iqbal / Thomas, Danny

Pediatric emergency care

2022 Volume 38, Issue 1, Page(s) e37–e42

Abstract: Objective: Mild traumatic brain injury (mTBI), or concussion, is a common health problem that has seen a recent increase in US adolescents. This study uses SMS text messaging (a mobile health [mHealth] tool) to report patient symptoms. We aim to better ... ...

Abstract	Objective: Mild traumatic brain injury (mTBI), or concussion, is a common health problem that has seen a recent increase in US adolescents. This study uses SMS text messaging (a mobile health [mHealth] tool) to report patient symptoms. We aim to better characterize mTBI recovery and hypothesize that this mHealth tool will have high retention rates and correlate with a conventional means of assessing symptoms, the Post-Concussion Symptom Inventory (PCSI). Methods: A prospective observational cohort pilot study. Thirty-one pediatric patients with acute mTBI were recruited to characterize their injury and report their symptoms via text messaging. Patients reported symptoms once every 3 days for the first 21 days, then once a week for 6 weeks. Results: There was a strong and positive correlation between the PCSI and the mHealth tool (rs = 0.875, P < 0.000, n = 22). Retention was 74% until symptom resolution and 42% until study completion. Patients with balance deficits had a significantly higher somatization score than those with normal balance (6.53 ± 3.25 vs 2.56 ± 2.30, t(22) = 3.211, P < 0.01). Conclusions: This pilot study demonstrates that this tool is a valid and easy-to-use method of reporting pediatric mTBI symptoms-it replicates and identifies novel findings. Our results suggest that there may be a relationship between balance and the manifestation of somatic symptoms. Retention rates were lower than predicted, indicating that text messaging may not be the ideal format in this population. Text messaging may still have other applications for short-term communication/symptom measurement.
MeSH term(s)	Adolescent ; Brain Concussion/diagnosis ; Child ; Humans ; Pilot Projects ; Post-Concussion Syndrome/diagnosis ; Text Messaging
Language	English
Publishing date	2022-01-01
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	632588-9
ISSN	1535-1815 ; 0749-5161
ISSN (online)	1535-1815
ISSN	0749-5161
DOI	10.1097/PEC.0000000000002596
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 2083: Show issues

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Article ; Online: Survivorship With Incrementally Faster Times to Primary Percutaneous Coronary Intervention (SWIFT-PPCI): A Systematic Review and Meta-Analysis.

Price, James / Rudman, Jordan / Schoenfeld, David / Thomas, Sarah Alice / Rees, Paul / Bloom, Ben / McCartin, Michael / Blumen, Ira / Thomas, Stephen H

The American journal of cardiology

2023 Volume 207, Page(s) 356–362

Abstract: In the United States, there are approximately 750,000 ST-elevation myocardial infarction cases each year. Streamlined care and rapid delivery for primary percutaneous coronary intervention (PPCI) is associated with improved survival. This systematic ... ...

Abstract	In the United States, there are approximately 750,000 ST-elevation myocardial infarction cases each year. Streamlined care and rapid delivery for primary percutaneous coronary intervention (PPCI) is associated with improved survival. This systematic review and meta-analysis aimed to generate a practical estimate of mortality savings for every notional 30-minute decrease in the time to achieving PPCI. Included studies were those that provided a specific absolute risk reduction for a specific reduction in pre-PPCI time. The eligible studies evaluated the survival benefit from pre-PPCI time savings measured in any interval ending with PPCI and commencing with objectively recorded timing, such as initial emergency call, first medical contact, or hospital arrival. Study planning called for the reporting of data as individual study results, with a pooled effect estimate of relative risk calculated with random-effects meta-analysis. A total of 1,088 records were eligible for review; 52 were reviewed in full text, with 4 studies (total patient n = 235,814, overall mortality 4.7% to 7.8%) included in the final analysis. All 4 studies reported significant time-related survival benefit over the study focus window of 60 to 180 minutes pre-PPCI. The number of lives saved per 100 cases for each 30-minute pre-PPCI time savings ranged from 0.8 to 1.9. The overall effect estimate generated was 0.753 (95% confidence interval 0.712 to 0.796), with acceptable heterogeneity (I
MeSH term(s)	Humans ; Survivorship ; Percutaneous Coronary Intervention/methods ; ST Elevation Myocardial Infarction/surgery ; Treatment Outcome
Language	English
Publishing date	2023-09-28
Publishing country	United States
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	80014-4
ISSN	1879-1913 ; 0002-9149
ISSN (online)	1879-1913
ISSN	0002-9149
DOI	10.1016/j.amjcard.2023.08.178
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Applications of Artificial Intelligence in Helicopter Emergency Medical Services: A Scoping Review.

Hsueh, Jennifer / Fritz, Christie / Thomas, Caroline E / Reimer, Andrew P / Reisner, Andrew T / Schoenfeld, David / Haimovich, Adrian / Thomas, Stephen H

Air medical journal

2023 Volume 43, Issue 2, Page(s) 90–95

Abstract: Objective: Recent systematic reviews of acute care medicine applications of artificial intelligence (AI) have focused on hospital and general prehospital uses. The purpose of this scoping review was to identify and describe the literature on AI use with ...

Abstract	Objective: Recent systematic reviews of acute care medicine applications of artificial intelligence (AI) have focused on hospital and general prehospital uses. The purpose of this scoping review was to identify and describe the literature on AI use with a focus on applications in helicopter emergency medical services (HEMS). Methods: A literature search was performed with specific inclusion and exclusion criteria. Articles were grouped by characteristics such as publication year and general subject matter with categoric and temporal trend analyses. Results: We identified 21 records focused on the use of AI in HEMS. These applications included both clinical and triage uses and nonclinical uses. The earliest study appeared in 2006, but over one third of the identified studies have been published in 2021 or later. The passage of time has seen an increased likelihood of HEMS AI studies focusing on nonclinical issues; for each year, the likelihood of a nonclinical focus had an odds ratio of 1.3. Conclusion: This scoping review provides overview and hypothesis-generating information regarding AI applications specific to HEMS. HEMS AI may be ultimately deployed in nonclinical arenas as much as or more than for clinical decision support. Future studies will inform future decisions as to how AI may improve HEMS systems design, asset deployment, and clinical care.
MeSH term(s)	Humans ; Air Ambulances ; Artificial Intelligence ; Emergency Medical Services ; Aircraft ; Triage
Language	English
Publishing date	2023-12-20
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2072853-0
ISSN	1532-6497 ; 1067-991X
ISSN (online)	1532-6497
ISSN	1067-991X
DOI	10.1016/j.amj.2023.11.012
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 5623: Show issues

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Article ; Online: Natural Experiment Outcomes Studies in Rotor Wing Air Medical Transport: Systematic Review and Meta-Analysis of Before-and-After and Helicopter-Unavailable Publications From 1970 to 2022.

Schoenfeld, David / Thomas, Caroline E / McCartin, Michael P / Blumen, Ira J / Galvagno, Samuel M / Thomas, Stephen H

Air medical journal

2023 Volume 43, Issue 2, Page(s) 124–132

Abstract: Objective: Helicopter emergency medical services (HEMS) is widely used for prehospital and interfacility transport, but there is a paucity of HEMS outcomes data from studies using randomized controlled trial designs. In the absence of robust randomized ... ...

Abstract	Objective: Helicopter emergency medical services (HEMS) is widely used for prehospital and interfacility transport, but there is a paucity of HEMS outcomes data from studies using randomized controlled trial designs. In the absence of robust randomized controlled trial evidence, judgments regarding HEMS potential benefit must be informed by observational data. Within the study design set of observational analyses, the natural experiment (NE) is notable for its high potential methodologic quality; NE designs are occasionally denoted "quasi-experimental." The aim of this study is to examine all NE outcomes studies in the HEMS literature and to discern what lessons can be learned from these potentially high-quality observational data. Methods: HEMS NE studies were identified during the development of a new HEMS Outcomes Assessment Research Database (HOARD). HOARD was constructed using a broad-ranging search of published and gray literature resources (eg, PubMed, Embase, and Google Scholar) that used variations of the terms "helicopter EMS," "air ambulance," and "air medical transport." Among the 221 studies ultimately included in HOARD, 16 NE publications describing 13 sets of observational data comprising myriad diagnostic groups were identified. Of these 16 HEMS NEs, 4 HEMS NE studies assessing trauma outcomes were used in a meta-analysis. A meta-analysis was also performed of 4 HEMS NE studies. Results: Although the disparity of studies (in terms of both case mix and end points) precluded the generation of a pooled effect estimate of an adjusted mortality benefit of HEMs versus ground emergency medical services, HEMS was found to be associated with outcomes improvement in 8 of the 13 cohorts. Conclusion: The weight of the NE evidence supports a conclusion of some form of HEMS-mediated outcomes improvement in a variety of patient types. Meta-analysis of 4 HEMS NE studies assessing trauma outcomes generated a model with acceptable heterogeneity (I
MeSH term(s)	Humans ; Air Ambulances ; Aircraft ; Emergency Medical Services ; Outcome Assessment, Health Care ; Databases, Factual ; Retrospective Studies ; Randomized Controlled Trials as Topic ; Observational Studies as Topic
Language	English
Publishing date	2023-12-05
Publishing country	United States
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	2072853-0
ISSN	1532-6497 ; 1067-991X
ISSN (online)	1532-6497
ISSN	1067-991X
DOI	10.1016/j.amj.2023.11.005
Database	MEDical Literature Analysis and Retrieval System OnLINE

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