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  1. Article ; Online: Preisträger stellen sich vor: Thomas Graier erhält den Versorgungsforschungspreis der ÖGDV 2022.

    Graier, Thomas

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2023  Volume 21, Issue 6, Page(s) 697–698

    Language German
    Publishing date 2023-06-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.15138_g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6148: Show issues Location:
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  2. Article ; Online: Yes (again) to local NO.

    Eroglu, Emrah / Michel, Thomas / Graier, Wolfgang F / Malli, Roland

    Nature chemical biology

    2020  Volume 16, Issue 6, Page(s) 606–607

    MeSH term(s) DNA ; Fluorescent Dyes
    Chemical Substances Fluorescent Dyes ; DNA (9007-49-2)
    Language English
    Publishing date 2020-06-19
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2202962-X
    ISSN 1552-4469 ; 1552-4450
    ISSN (online) 1552-4469
    ISSN 1552-4450
    DOI 10.1038/s41589-020-0552-7
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    Zs.MG 90: Show issues

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  3. Article ; Online: Pityriasis rosea in der Schwangerschaft: Eine Fallserie und Literaturübersicht.

    Wenger-Oehn, Lena / Graier, Thomas / Ambros-Rudolph, Christina / Müllegger, Robert / Bittighofer, Christina / Wolf, Peter / Hofer, Angelika

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2022  Volume 20, Issue 7, Page(s) 953–960

    Language English
    Publishing date 2022-07-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14763_g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pityriasis rosea in pregnancy: A case series and literature review.

    Wenger-Oehn, Lena / Graier, Thomas / Ambros-Rudolph, Christina / Müllegger, Robert / Bittighofer, Christina / Wolf, Peter / Hofer, Angelika

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2022  Volume 20, Issue 7, Page(s) 953–959

    Abstract: Background and objective: Pityriasis rosea (PR), a common skin disease in young adults, may adversely affects the course of pregnancy and the unborn child.: Patients and methods: Data from forty-six pregnant women with PR seen in the dermatological ... ...

    Abstract Background and objective: Pityriasis rosea (PR), a common skin disease in young adults, may adversely affects the course of pregnancy and the unborn child.
    Patients and methods: Data from forty-six pregnant women with PR seen in the dermatological university clinic between 2003 and 2018 were analyzed and compared with patient data (n = 53) from previously published studies to determine the incidence and risk factors for an unfavorable pregnancy outcome after PR infection.
    Results: Unfavorable pregnancy outcomes (defined as miscarriage, preterm delivery before week 37 of gestation, or birth weight < 2,500 g) were significantly less frequent in our study population than in a pooled cohort obtained from previously published studies (10.9 % vs. 39.6 %; P = 0.0012). Analysis of pooled data from our study and from previous studies revealed that the week of pregnancy at onset of PR was inversely associated with an unfavorable outcome (odds ratio [OR] = 0.937; 95 % CI 0.883 to 0.993). In addition, duration of PR (OR = 1.432; 95 % CI 1.129 to 1.827), additional extracutaneous symptoms (OR = 4.112; 95 % CI 1.580 to 10.23), and widespread rash distribution (OR 5.203, 95 % CI 1.702 to 14.89) were directly associated with unfavorable outcome.
    Conclusion: In most cases, PR does not influence pregnancy or birth outcomes.
    MeSH term(s) Cohort Studies ; Female ; Humans ; Incidence ; Infant, Newborn ; Pityriasis Rosea/diagnosis ; Pityriasis Rosea/epidemiology ; Pregnancy ; Pregnancy Complications/diagnosis ; Pregnancy Complications/epidemiology ; Risk Factors ; Young Adult
    Language English
    Publishing date 2022-05-26
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14763
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  5. Article ; Online: Metabolic Profiling of Single Cancer Cells Using Mitochondrial ATP Probes.

    Rauter, Thomas / Depaoli, Maria R / Bischof, Helmut / Graier, Wolfgang F / Malli, Roland

    STAR protocols

    2020  Volume 1, Issue 2, Page(s) 100048

    Abstract: The metabolic activity of cells is interrelated with cell signaling, functions, and fate. Uncontrolled cancer cell proliferation requires metabolic adaptations. Research focusing on understanding the characteristics of cell metabolism is crucial for the ... ...

    Abstract The metabolic activity of cells is interrelated with cell signaling, functions, and fate. Uncontrolled cancer cell proliferation requires metabolic adaptations. Research focusing on understanding the characteristics of cell metabolism is crucial for the development of novel diagnostic and therapeutic strategies. Here, we describe protocols for the ATP profiling of single cancer cells by fluorescence live-cell imaging. In response to distinct metabolic inhibitions, we record individual mitochondrial ATP dynamics using established Förster resonance energy transfer-based genetically encoded fluorescent ATP probes. For complete details on the use and execution of this protocol, please refer to Depaoli et al. (2018).
    MeSH term(s) Adenosine Triphosphate/analysis ; Adenosine Triphosphate/chemistry ; Adenosine Triphosphate/metabolism ; Animals ; Cell Line, Tumor ; Fluorescence Resonance Energy Transfer ; Fluorescent Dyes/analysis ; Fluorescent Dyes/chemistry ; Fluorescent Dyes/metabolism ; Humans ; Mitochondria/chemistry ; Mitochondria/metabolism ; Molecular Imaging ; Rats ; Single-Cell Analysis/methods ; Tumor Cells, Cultured/cytology ; Tumor Cells, Cultured/metabolism
    Chemical Substances Fluorescent Dyes ; Adenosine Triphosphate (8L70Q75FXE)
    Language English
    Publishing date 2020-06-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2666-1667
    ISSN (online) 2666-1667
    DOI 10.1016/j.xpro.2020.100048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Long-Term Course of Polymorphic Light Eruption: A Registry Analysis.

    Gruber-Wackernagel, Alexandra / Schug, Tanja / Graier, Thomas / Legat, Franz J / Rinner, Hanna / Hofer, Angelika / Quehenberger, Franz / Wolf, Peter

    Frontiers in medicine

    2021  Volume 8, Page(s) 694281

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-07-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2021.694281
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  7. Article: Furin Expression in Patients With Psoriasis-A Patient Cohort Endangered to SARS-COV2?

    Graier, Thomas / Golob-Schwarzl, Nicole / Weger, Wolfgang / Benezeder, Theresa / Painsi, Clemens / Salmhofer, Wolfgang / Wolf, Peter

    Frontiers in medicine

    2021  Volume 8, Page(s) 624462

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-02-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2021.624462
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  8. Article ; Online: Monoglyceride Lipase Deficiency Is Associated with Altered Thrombogenesis in Mice.

    Goeritzer, Madeleine / Kuentzel, Katharina B / Beck, Sarah / Korbelius, Melanie / Rainer, Silvia / Bradić, Ivan / Kolb, Dagmar / Mussbacher, Marion / Schrottmaier, Waltraud C / Assinger, Alice / Schlagenhauf, Axel / Rost, René / Gottschalk, Benjamin / Eichmann, Thomas O / Züllig, Thomas / Graier, Wolfgang F / Vujić, Nemanja / Kratky, Dagmar

    International journal of molecular sciences

    2023  Volume 24, Issue 4

    Abstract: Monoglyceride lipase (MGL) hydrolyzes monoacylglycerols (MG) to glycerol and one fatty acid. Among the various MG species, MGL also degrades 2-arachidonoylglycerol, the most abundant endocannabinoid and potent activator of the cannabinoid receptors 1 and ...

    Abstract Monoglyceride lipase (MGL) hydrolyzes monoacylglycerols (MG) to glycerol and one fatty acid. Among the various MG species, MGL also degrades 2-arachidonoylglycerol, the most abundant endocannabinoid and potent activator of the cannabinoid receptors 1 and 2. We investigated the consequences of MGL deficiency on platelet function using systemic (Mgl
    MeSH term(s) Animals ; Mice ; Endocannabinoids/metabolism ; Lipolysis ; Mice, Inbred C57BL ; Mice, Knockout ; Monoacylglycerol Lipases/genetics ; Monoglycerides
    Chemical Substances Endocannabinoids ; Monoacylglycerol Lipases (EC 3.1.1.23) ; Monoglycerides ; Mgll protein, mouse (EC 3.1.1.23)
    Language English
    Publishing date 2023-02-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24043116
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  9. Article ; Online: Different Roles of p62 (SQSTM1) Isoforms in Keratin-Related Protein Aggregation.

    Somlapura, Meghana / Gottschalk, Benjamin / Lahiri, Pooja / Kufferath, Iris / Pabst, Daniela / Rülicke, Thomas / Graier, Wolfgang F / Denk, Helmut / Zatloukal, Kurt

    International journal of molecular sciences

    2021  Volume 22, Issue 12

    Abstract: p62/Sequestosome-1 (p62) is a multifunctional adaptor protein and is also a constant component of disease-associated protein aggregates, including Mallory-Denk bodies (MDBs), in steatohepatitis and hepatocellular carcinoma. We investigated the ... ...

    Abstract p62/Sequestosome-1 (p62) is a multifunctional adaptor protein and is also a constant component of disease-associated protein aggregates, including Mallory-Denk bodies (MDBs), in steatohepatitis and hepatocellular carcinoma. We investigated the interaction of the two human p62 isoforms, p62-H1 (full-length isoform) and p62-H2 (partly devoid of PB1 domain), with keratins 8 and 18, the major components of MDBs. In human liver, p62-H2 is expressed two-fold higher compared to p62-H1 at the mRNA level and is present in slightly but not significantly higher concentrations at the protein level. Co-transfection studies in CHO-K1 cells, PLC/PRF/5 cells as well as p62
    MeSH term(s) Animals ; CHO Cells ; Cricetulus ; Humans ; Keratins/genetics ; Keratins/metabolism ; Mice ; Mice, Knockout ; Protein Aggregates ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Sequestosome-1 Protein/genetics ; Sequestosome-1 Protein/metabolism
    Chemical Substances Protein Aggregates ; Protein Isoforms ; SQSTM1 protein, human ; Sequestosome-1 Protein ; Sqstm1 protein, mouse ; Keratins (68238-35-7)
    Language English
    Publishing date 2021-06-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms22126227
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  10. Article ; Online: Metabolic Profiling of Single Cancer Cells Using Mitochondrial ATP Probes

    Thomas Rauter / Maria R. Depaoli / Helmut Bischof / Wolfgang F. Graier / Roland Malli

    STAR Protocols, Vol 1, Iss 2, Pp 100048- (2020)

    2020  

    Abstract: Summary: The metabolic activity of cells is interrelated with cell signaling, functions, and fate. Uncontrolled cancer cell proliferation requires metabolic adaptations. Research focusing on understanding the characteristics of cell metabolism is crucial ...

    Abstract Summary: The metabolic activity of cells is interrelated with cell signaling, functions, and fate. Uncontrolled cancer cell proliferation requires metabolic adaptations. Research focusing on understanding the characteristics of cell metabolism is crucial for the development of novel diagnostic and therapeutic strategies. Here, we describe protocols for the ATP profiling of single cancer cells by fluorescence live-cell imaging. In response to distinct metabolic inhibitions, we record individual mitochondrial ATP dynamics using established Förster resonance energy transfer-based genetically encoded fluorescent ATP probes.For complete details on the use and execution of this protocol, please refer to Depaoli et al. (2018).
    Keywords Science (General) ; Q1-390
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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