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  1. Article ; Online: Richard Ho-Ping Sia: pioneer of infectiology in China.

    Liu, Xudong / Li, Yuanmeng / Li, Naishi

    Protein & cell

    2022  Volume 14, Issue 4, Page(s) 235–237

    Language English
    Publishing date 2022-11-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2543451-2
    ISSN 1674-8018 ; 1674-8018
    ISSN (online) 1674-8018
    ISSN 1674-8018
    DOI 10.1093/procel/pwac050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Study of the Ping An Health App Based on User Reviews with Sentiment Analysis.

    Fang, Fang / Zhou, Yin / Ying, Shi / Li, Zhijuan

    International journal of environmental research and public health

    2023  Volume 20, Issue 2

    Abstract: By mining the dimensional sentiment and dimension weight of the Ping An Health App reviews ... suggestions for the Ping An Health App operators to improve user satisfaction. Firstly, the topic model is ... of the Ping An Health App in the Apple App Store, users' concerns about Ping An Health App can be summarized ...

    Abstract By mining the dimensional sentiment and dimension weight of the Ping An Health App reviews, this paper explores the changing trend of the influence of dimensions on user satisfaction and provides suggestions for the Ping An Health App operators to improve user satisfaction. Firstly, the topic model is used to identify the topic of user comments, and then the fine-grained sentiment analysis method is used to calculate the sentiment and weight of each dimension. Finally, the changing trend of the weight of each dimension and the changing trend of user satisfaction of each dimension are drawn. Based on the reviews of the Ping An Health App in the Apple App Store, users' concerns about Ping An Health App can be summarized into seven main dimensions: Usage, Bug report, Reliability, Feature information, Services, Other apps, and User Background. The "Feature information" dimension and "Reliability" dimension have a great impact on user satisfaction with the Ping An Health App, while the "Bug report" dimension has the lowest user satisfaction.
    MeSH term(s) Mobile Applications ; Sentiment Analysis ; Personal Satisfaction ; Attitude
    Language English
    Publishing date 2023-01-16
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20021591
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Yu-Ping-Feng-San alleviates inflammation in atopic dermatitis mice by TLR4/MyD88/NF-κB pathway.

    Nie, Jing / Jiang, Xiaoyuan / Wang, Guomi / Xu, Yanan / Pan, Rui / Yu, Wantao / Li, Yuanwen / Wang, Jingxiao

    Journal of ethnopharmacology

    2024  Volume 329, Page(s) 118092

    Abstract: Ethnopharmacological relevance: Yu-Ping-Feng-San (YPF) is a traditional Chinese medicine formula ...

    Abstract Ethnopharmacological relevance: Yu-Ping-Feng-San (YPF) is a traditional Chinese medicine formula that has therapeutic effects on allergic diseases such as allergic rhinitis and asthma. However, its potential efficacy and mechanism in the treatment of atopic dermatitis (AD) has not been extensively illustrated.
    Aim of the study: The purpose of this study was to investigate the efficacy and possible mechanisms of YPF in AD pathogenesis.
    Methods: Network pharmacology and GEO data mining were adopted to firstly identify the potential mechanisms of YPF on AD. Then DNCB induced-AD murine model was established to test the efficacy of YPF and verify its effects on inflammatory cytokines and NF-κB pathway. In addition, molecular docking was performed to detect the binding affinity of YPF's active components with NF-κB pathway related molecules.
    Results: Network pharmacology and human data mining suggested that YPF may act on the NF-κB pathway in AD pathogenesis. With DNCB mice model, we found that YPF significantly improved AD symptoms, reduced SCORAD scores, and alleviated skin tissue inflammation in mice. At the same time, the expression of inflammatory cytokines, TNF-α, sPLA2-IIA and IL-6, was down-regulated. Moreover, YPF suppressed TLR4/MyD88/NF-κB pathway in situ in a dose-dependent manner. Molecular docking further confirmed that seven compounds in YPF had exceptional binding properties with TNF-α, IL-6 and TLR4.
    Conclusion: YPF may help the recovery of AD by inhibiting the TLR4/MyD88/NF-κB pathway, which provides novel insights for the treatment of AD by YPF.
    Language English
    Publishing date 2024-04-09
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2024.118092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effects of Yu-Ping-Feng polysaccharides on animal growth performance and immune function: a review.

    Chu, Huangbin / Zong, Yi / Yang, Hong / Chen, Siyu / Ma, Zheng / Li, Hua

    Frontiers in veterinary science

    2023  Volume 10, Page(s) 1260208

    Abstract: Yu-Ping-Feng polysaccharides (YPF-P) ...

    Abstract Yu-Ping-Feng polysaccharides (YPF-P)
    Language English
    Publishing date 2023-09-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2023.1260208
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comprehensive evaluation of the resistance to shoot shriveling before and after sprouting in different varieties of Ping’ou hybrid hazelnut

    Haizhe Gao / Zhiguo Jia / Lirong Zhang / Zhang Li

    Frontiers in Forests and Global Change, Vol

    2024  Volume 6

    Abstract: IntroductionThe hybrid hazelnut is an important fruit tree species known for its high productivity and disease resistance. However, during the growth process of hybrid hazelnuts, issues such as branch withering and bud wrinkling have attracted ... ...

    Abstract IntroductionThe hybrid hazelnut is an important fruit tree species known for its high productivity and disease resistance. However, during the growth process of hybrid hazelnuts, issues such as branch withering and bud wrinkling have attracted significant attention. These phenomena severely impact the normal development and yield of the plants. This study aimed to investigate the relationship between the resistance to shoot emergence and physiological changes in six hazel tree varieties by comprehensively analyzing their resistance to shoot emergence.MethodSix widely cultivated hazelnut hybrid varieties were selected for physiological measurements and field surveys using one-year-old branches and buds as test materials. The resistance to shoot emergence of different hazel tree varieties was evaluated through correlation analysis, principal component analysis, and membership function evaluation.ResultsThe results showed that the length and width of hazel buds gradually increased while the thickness first increased and then decreased before and after bud burst. The carbohydrate levels of the ‘Dawei’, ‘Pingou 110’, and ‘84–237’ varieties were significantly higher than those of other varieties. The content of reducing sugars and starch in hazel buds generally increased and then decreased during the bud burst process, while α-amylase activity showed a decreasing trend followed by an increasing trend. The antioxidative enzyme activity of ‘Dawei’ was significantly higher than that of other varieties on different sampling dates. The soluble protein content, POD enzyme activity, and CAT enzyme activity of hazel buds for the six varieties gradually decreased. The moisture content of ‘Pingou 210’ shoots was significantly higher than that of other varieties during the peak emergence period. The correlation analysis results showed that the bud burst rate of hazel trees was positively correlated with the length, width, thickness, reducing sugar content, starch content, POD enzyme activity, CAT enzyme activity, and shoot ...
    Keywords Ping’ou hybrid hazelnut ; germinating buds ; shoot shriveling ; physiological changes ; comprehensive assessment ; Forestry ; SD1-669.5 ; Environmental sciences ; GE1-350
    Subject code 571
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Anti-inflammatory effect of Yu-Ping-Feng-San

    Yang, Zhong-Shan / Yan, Jin-Yuan / Han, Ni-Ping / Zhou, Wei / Cheng, Yu / Zhang, Xiao-Mei / Li, Ning / Yuan, Jia-Li

    Iranian journal of basic medical sciences

    2016  Volume 19, Issue 9, Page(s) 993–1002

    Abstract: Objectives: Yu-Ping-Feng-San (YPFS) is a classical traditional Chinese medicine that is widely ...

    Abstract Objectives: Yu-Ping-Feng-San (YPFS) is a classical traditional Chinese medicine that is widely used for treatment of the diseases in respiratory systems, including chronic obstructive pulmonary disease (COPD) recognized as chronic inflammatory disease. However, the molecular mechanism remains unclear. Here we detected the factors involved in transforming growth factor beta 1 (TGF-β1)/Smad2 signaling pathway and inflammatory cytokines, to clarify whether YPFS could attenuate inflammatory response dependent on TGF-β1/Smad2 signaling in COPD rats or cigarette smoke extract (CSE)-treated human bronchial epithelial (Beas-2B) cells.
    Materials and methods: The COPD rat model was established by exposure to cigarette smoke and intratracheal instillation of lipopolysaccharide, YPFS was administered to the animals. The efficacy of YPFS was evaluated by comparing the severity of pulmonary pathological damage, pro-inflammation cytokines, collagen related genes and the activation of TGF-β1/Smad2 signaling pathway. Furthermore, CSE-treated cells were employed to confirm whether the effect of YPFS was dependent on the TGF-β1/Smad2 signaling via knockdown Smad2 (Si-RNA), or pretreatment with the inhibitor of TGF-β1.
    Results: Administration of YPFS effectively alleviated injury of lung, suppressed releasing of pro-inflammatory cytokines and collagen deposition in COPD animals (
    Conclusion: YPFS accomplished anti-inflammatory effects mainly by suppressing phosphorylation of Smad2, TGF-β1/Smad2 signaling pathway was required for YPFS-mediated anti-inflammation in COPD rats or CSE-treated Beas-2B cells.
    Language English
    Publishing date 2016-10-17
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2500485-2
    ISSN 2008-3874 ; 2008-3866
    ISSN (online) 2008-3874
    ISSN 2008-3866
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A mini review of Yu-Ping-Feng polysaccharides

    Yang Liu / Binbin Tong / Shuangxing Wang / Gen Li / Yuansheng Tan / Hui Yu / Kelin Yang / Yingying Yu

    Aquaculture Reports, Vol 20, Iss , Pp 100697- (2021)

    Their biological activities and potential applications in aquaculture

    2021  

    Abstract: ... become a focus of attention in many fields, particularly in medical research industry. Yu-Ping-Feng (YPF ... not studied. Under the guidance of the Pharmacological Efficacy Index, we have extracted Yu-Ping-Feng ...

    Abstract Polysaccharides, one of the important active ingredients of traditional Chinese herbal medicine, become a focus of attention in many fields, particularly in medical research industry. Yu-Ping-Feng (YPF) is a primary component of many traditional Chinese medicine prescriptions, and it’s proven to be significantly beneficial to human health. In recent years, polysaccharides from YPF have been well documented after successful isolation and purification, but the polysaccharides from YPF post-processing wastes are not studied. Under the guidance of the Pharmacological Efficacy Index, we have extracted Yu-Ping-Feng polysaccharides (YPF-P) from the wastes of YPF in our previous work. Our previous findings showed that YPF-P promote the growth, enhance immunity and organ structure or function of cultured fish northern snakehead fish (Channa argus) and grass carp (Ctenopharyngodon idellus), and significantly improve the intestinal microflora of fish. This paper reviews the current status of YPF-P and their application in aquaculture, including the development of green feed for aquatic animals and the re-utilization of the YPF wastes. This series of work is a way to have the best of both worlds, not only to realize the rational treatment of medical wastes, but also to effectively use the wastes, to find a green raw material for aquatic feed.
    Keywords Traditional Chinese medicine ; Yu-Ping-Feng polysaccharides ; Feed additive ; Aquaculture. Fisheries. Angling ; SH1-691
    Subject code 540
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Yu-Ping-Feng Formula Ameliorates Alveolar-Capillary Barrier Injury Induced by Exhausted-Exercise

    Wang, Di / Li, Quan / Pan, Chun-Shui / Yan, Li / Sun, Kai / Wang, Xiao-Yi / Anwaier, Gulinigaer / Liao, Qian-Zan / Xie, Ting-Ting / Fan, Jing-Yu / Huo, Xin-Mei / Wang, Yuan / Han, Jing-Yan

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 891802

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-06-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.891802
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Tang-Ping-San Decoction Remodel Intestinal Flora and Barrier to Ameliorate Type 2 Diabetes Mellitus in Rodent Model.

    Yin, Wen / Zhang, Si-Qi / Pang, Wen-Lin / Chen, Xiao-Jiao / Wen, Jing / Hou, Jiong / Wang, Cui / Song, Li-Yun / Qiu, Zhen-Ming / Liang, Peng-Tao / Yuan, Jia-Li / Yang, Zhong-Shan / Bian, Yao

    Diabetes, metabolic syndrome and obesity : targets and therapy

    2022  Volume 15, Page(s) 2563–2581

    Abstract: ... metabolic diseases and promote the progression of T2DM. Tang-ping-san (TPS) decoction can effectively treat T2DM ...

    Abstract Purpose: Type 2 diabetes mellitus (T2DM) is a complex genetic disease associated with genetic and environmental factors. Previous studies have shown that changes in the gut microbiota may affect the development of host metabolic diseases and promote the progression of T2DM. Tang-ping-san (TPS) decoction can effectively treat T2DM. However, its specific mechanisms must be evaluated.
    Patients and methods: In the present study, we established an animal model of T2DM using a high‑fat diet (HFD) with intraperitoneal injection streptozotocin injection.
    Results: The therapeutic effect of TPS decoction on T2DM in mice was initially evaluated. TPS decoction was found to improve hyperglycemia, hyperlipidemia, insulin resistance, and pathological liver, pancreatic, and colon changes. Moreover, it reduced the pro-inflammatory cytokine levels. Based on 16SrRNA sequencing, TPS decoction reduced the
    Conclusion: TPS decoction improves T2DM and liver function and reduces the risk of hyperglycemia, hyperlipidemia, insulin resistance, pathological organ changes, and inflammatory reactions. The mechanism of TPS decoction in T2DM can be correlated with the reversal of gut microbiota dysfunction and repair of the intestinal mucosal barrier.
    Language English
    Publishing date 2022-08-20
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494854-8
    ISSN 1178-7007
    ISSN 1178-7007
    DOI 10.2147/DMSO.S375572
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Erratum: SHENGBO ZHOU (), LI HE (), SIYU MA (), SHUJUN XU (), QIANG ZHAI (), PING GUAN (), HUI WANG ()amp; JINGSONG SHI () (2022)Taxonomic status of Rana nigromaculata mongolia and the validity of Pelophylax tenggerensis (Anura, Ranidae) Zootaxa 5165 (4): 486500.

    Zhou, Shengbo / He, L I / Ma, Siyu / Xu, Shujun / Zhai, Qiang / Guan, Ping / Wang, Hui / Shi, Jingsong

    Zootaxa

    2022  Volume 5174, Issue 5, Page(s) 600

    Language English
    Publishing date 2022-08-12
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1175-5334
    ISSN (online) 1175-5334
    DOI 10.11646/zootaxa.5174.5.8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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