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  1. Article ; Online: Prevalence, admission rates and hypoxia due to COVID-19 in patients with rheumatic disorders treated with targeted synthetic or biologic disease modifying antirheumatic drugs or methotrexate: a nationwide study from Iceland.

    Bjornsson, Aron Hjalti / Grondal, Gerdur / Kristjansson, Mar / Jonsdottir, Thorunn / Love, Thorvardur Jon / Gudbjornsson, Bjorn

    Annals of the rheumatic diseases

    2021  Volume 80, Issue 5, Page(s) 671–672

    MeSH term(s) Antirheumatic Agents/therapeutic use ; COVID-19/complications ; Hospitalization/statistics & numerical data ; Humans ; Hypoxia/virology ; Iceland/epidemiology ; Methotrexate/therapeutic use ; Prevalence ; Rheumatic Diseases/drug therapy ; Rheumatic Diseases/epidemiology ; SARS-CoV-2
    Chemical Substances Antirheumatic Agents ; Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2021-01-05
    Publishing country England
    Document type Letter
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2020-219564
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.114: Show issues Location:
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    Zs.MO 167: Show issues

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  2. Article ; Online: Offita er ekki alltaf offita: Cushing-sjúkdómur, sjúkratilfelli

    Bjornsson, Aron Hjalti / Hardarson, Thorgeir Orri / Olafsson, Ingvar Hakon / Ragnarsson, Oskar / Sigurjonsdottir, Helga Agusta

    Laeknabladid

    2020  Volume 106, Issue 10, Page(s) 460–463

    Abstract: Woman in her thirties presented to the emergency room with a two-week history of worsening headache and diplopia. For eight years she had suffered from progressive weight gain, diabetes and hypertension that didn't improve with lifestyle modification. A ... ...

    Title translation Obesity isn't always obesity: Cushing's disease - case report.
    Abstract Woman in her thirties presented to the emergency room with a two-week history of worsening headache and diplopia. For eight years she had suffered from progressive weight gain, diabetes and hypertension that didn't improve with lifestyle modification. A lumbar puncture demonstrated increased intracranial pressure and MRI a pituitary adenoma. Physical examination was consistent with Cushing's syndrome and endocrine workup confirmed Cushing's disease. Treatment was complex, including unsuccessful pituitary surgery and gamma knife radiosurgery, and eventually bilateral adrenalectomy with subsequent development of Nelsons syndrome. This case illustrates the diagnostic delay that many patients with CD suffer from.
    MeSH term(s) ACTH-Secreting Pituitary Adenoma/complications ; ACTH-Secreting Pituitary Adenoma/diagnostic imaging ; ACTH-Secreting Pituitary Adenoma/surgery ; Adenoma/complications ; Adenoma/diagnostic imaging ; Adenoma/surgery ; Adult ; Delayed Diagnosis ; Female ; Humans ; Magnetic Resonance Imaging ; Obesity/diagnosis ; Obesity/etiology ; Pituitary ACTH Hypersecretion/diagnosis ; Pituitary ACTH Hypersecretion/etiology ; Risk Factors ; Treatment Outcome
    Language Icelandic
    Publishing date 2020-09-29
    Publishing country Iceland
    Document type Case Reports
    ZDB-ID 806661-9
    ISSN 1670-4959 ; 0023-7213
    ISSN (online) 1670-4959
    ISSN 0023-7213
    DOI 10.17992/lbl.2020.10.601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Fyrsta meðferð með tocilizumab við COVID-19 hérlendis - sjúkratilfelli

    Bjornsson, Aron Hjalti / Olafsdottir, Thorbjorg / Thormar, Katrin Maria / Kristjansson, Mar / Thorisdottir, Anna Sesselja / Ludviksson, Bjorn Runar / Guðmundsson, Sigurdur / Gottfredsson, Magnus

    Laeknabladid

    2020  Volume 106, Issue 5, Page(s) 247–250

    Abstract: A gentleman in his early fifties became ill with flu-like symptoms after vacationing abroad and was diagnosed with COVID-19 after returning to Iceland. A few days later he was admitted to the University Hospital, Landspitali, due to worsening respiratory ...

    Title translation First case of COVID-19 treated with tocilizumab in Iceland.
    Abstract A gentleman in his early fifties became ill with flu-like symptoms after vacationing abroad and was diagnosed with COVID-19 after returning to Iceland. A few days later he was admitted to the University Hospital, Landspitali, due to worsening respiratory symptoms and severe fatigue. A computed tomography scan of lthe lungs showed diffuse bilateral consolidations and ground glass changes. He developed respiratory failure and was transferred to the intensive care unit where he received further treatment, including tocilizumab (IL-6 receptor inhibitor). He subsequently showed clinical improvement and did not require endotracheal intubation.
    MeSH term(s) Antibodies, Monoclonal, Humanized/therapeutic use ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/drug therapy ; Humans ; Iceland ; Lung/diagnostic imaging ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/drug therapy ; SARS-CoV-2 ; Tomography, X-Ray Computed ; Travel ; Treatment Outcome
    Chemical Substances Antibodies, Monoclonal, Humanized ; tocilizumab (I031V2H011)
    Keywords covid19
    Language Icelandic
    Publishing date 2020-05-05
    Publishing country Iceland
    Document type Case Reports ; Journal Article
    ZDB-ID 806661-9
    ISSN 1670-4959 ; 0023-7213
    ISSN (online) 1670-4959
    ISSN 0023-7213
    DOI 10.17992/lbl.2020.05.581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Development of a prognostic model of COVID-19 severity: a population-based cohort study in Iceland.

    Eythorsson, Elias / Bjarnadottir, Valgerdur / Runolfsdottir, Hrafnhildur Linnet / Helgason, Dadi / Ingvarsson, Ragnar Freyr / Bjornsson, Helgi K / Olafsdottir, Lovisa Bjork / Bjarnadottir, Solveig / Agustsson, Arnar Snaer / Oskarsdottir, Kristin / Thorvaldsson, Hrafn Hliddal / Kristjansdottir, Gudrun / Bjornsson, Aron Hjalti / Emilsdottir, Arna R / Armannsdottir, Brynja / Gudlaugsson, Olafur / Hansdottir, Sif / Gottfredsson, Magnus / Bjarnason, Agnar /
    Sigurdsson, Martin I / Indridason, Olafur S / Palsson, Runolfur

    Diagnostic and prognostic research

    2022  Volume 6, Issue 1, Page(s) 17

    Abstract: Background: The severity of SARS-CoV-2 infection varies from asymptomatic state to severe respiratory failure and the clinical course is difficult to predict. The aim of the study was to develop a prognostic model to predict the severity of COVID-19 in ... ...

    Abstract Background: The severity of SARS-CoV-2 infection varies from asymptomatic state to severe respiratory failure and the clinical course is difficult to predict. The aim of the study was to develop a prognostic model to predict the severity of COVID-19 in unvaccinated adults at the time of diagnosis.
    Methods: All SARS-CoV-2-positive adults in Iceland were prospectively enrolled into a telehealth service at diagnosis. A multivariable proportional-odds logistic regression model was derived from information obtained during the enrollment interview of those diagnosed between February 27 and December 31, 2020 who met the inclusion criteria. Outcomes were defined on an ordinal scale: (1) no need for escalation of care during follow-up; (2) need for urgent care visit; (3) hospitalization; and (4) admission to intensive care unit (ICU) or death. Missing data were multiply imputed using chained equations and the model was internally validated using bootstrapping techniques. Decision curve analysis was performed.
    Results: The prognostic model was derived from 4756 SARS-CoV-2-positive persons. In total, 375 (7.9%) only required urgent care visits, 188 (4.0%) were hospitalized and 50 (1.1%) were either admitted to ICU or died due to complications of COVID-19. The model included age, sex, body mass index (BMI), current smoking, underlying conditions, and symptoms and clinical severity score at enrollment. On internal validation, the optimism-corrected Nagelkerke's R
    Conclusion: Our prognostic model can accurately predict the later need for urgent outpatient evaluation, hospitalization, and ICU admission and death among unvaccinated SARS-CoV-2-positive adults in the general population at the time of diagnosis, using information obtained by telephone interview.
    Language English
    Publishing date 2022-09-08
    Publishing country England
    Document type Journal Article
    ISSN 2397-7523
    ISSN (online) 2397-7523
    DOI 10.1186/s41512-022-00130-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Corrigendum to "A Clinical Decision Support System for the Diagnosis, Fracture Risks and Treatment of Osteoporosis".

    Halldorsson, Bjarni V / Bjornsson, Aron Hjalti / Gudmundsson, Haukur Tyr / Birgisson, Elvar Orn / Ludviksson, Bjorn Runar / Gudbjornsson, Bjorn

    Computational and mathematical methods in medicine

    2017  Volume 2017, Page(s) 5472789

    Abstract: This corrects the article DOI: 10.1155/2015/189769.]. ...

    Abstract [This corrects the article DOI: 10.1155/2015/189769.].
    Language English
    Publishing date 2017-06-29
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2252430-7
    ISSN 1748-6718 ; 1748-670X ; 1027-3662
    ISSN (online) 1748-6718
    ISSN 1748-670X ; 1027-3662
    DOI 10.1155/2017/5472789
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  6. Article: Fyrsta meðferð með tocilizumab við COVID-19 hérlendis - sjúkratilfelli/ [First case of COVID-19 treated with tocilizumab in Iceland]

    Bjornsson, Aron Hjalti / Olafsdottir, Thorbjorg / Thormar, Katrin Maria / Kristjansson, Mar / Thorisdottir, Anna Sesselja / Ludviksson, Bjorn Runar / Guðmundsson, Sigurdur / Gottfredsson, Magnus

    Laeknabladid

    Abstract: A gentleman in his early fifties became ill with flu-like symptoms after vacationing abroad and was diagnosed with COVID-19 after returning to Iceland. A few days later he was admitted to the University Hospital, Landspitali, due to worsening respiratory ...

    Abstract A gentleman in his early fifties became ill with flu-like symptoms after vacationing abroad and was diagnosed with COVID-19 after returning to Iceland. A few days later he was admitted to the University Hospital, Landspitali, due to worsening respiratory symptoms and severe fatigue. A computed tomography scan of lthe lungs showed diffuse bilateral consolidations and ground glass changes. He developed respiratory failure and was transferred to the intensive care unit where he received further treatment, including tocilizumab (IL-6 receptor inhibitor). He subsequently showed clinical improvement and did not require endotracheal intubation.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32367812
    Database COVID19

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  7. Article: [First case of COVID-19 treated with tocilizumab in Iceland]

    Bjornsson, Aron Hjalti / Olafsdottir, Thorbjorg / Thormar, Katrin Maria / Kristjansson, Mar / Thorisdottir, Anna Sesselja / Ludviksson, Bjorn Runar / Guethmundsson, Sigurdur / Gottfredsson, Magnus

    Laeknabladid

    Abstract: A gentleman in his early fifties became ill with flu-like symptoms after vacationing abroad and was diagnosed with COVID-19 after returning to Iceland A few days later he was admitted to the University Hospital, Landspitali, due to worsening respiratory ... ...

    Abstract A gentleman in his early fifties became ill with flu-like symptoms after vacationing abroad and was diagnosed with COVID-19 after returning to Iceland A few days later he was admitted to the University Hospital, Landspitali, due to worsening respiratory symptoms and severe fatigue A computed tomography scan of lthe lungs showed diffuse bilateral consolidations and ground glass changes He developed respiratory failure and was transferred to the intensive care unit where he received further treatment, including tocilizumab (IL-6 receptor inhibitor) He subsequently showed clinical improvement and did not require endotracheal intubation
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #207212
    Database COVID19

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  8. Article ; Online: Corrigendum to “A Clinical Decision Support System for the Diagnosis, Fracture Risks and Treatment of Osteoporosis”

    Bjarni V. Halldorsson / Aron Hjalti Bjornsson / Haukur Tyr Gudmundsson / Elvar Orn Birgisson / Bjorn Runar Ludviksson / Bjorn Gudbjornsson

    Computational and Mathematical Methods in Medicine, Vol

    2017  Volume 2017

    Keywords Computer applications to medicine. Medical informatics ; R858-859.7
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: A Clinical Decision Support System for the Diagnosis, Fracture Risks and Treatment of Osteoporosis

    Bjarni V. Halldorsson / Aron Hjalti Bjornsson / Haukur Tyr Gudmundsson / Elvar Orn Birgisson / Bjorn Runar Ludviksson / Bjorn Gudbjornsson

    Computational and Mathematical Methods in Medicine, Vol

    2015  Volume 2015

    Keywords Computer applications to medicine. Medical informatics ; R858-859.7 ; Medicine (General) ; R5-920 ; Medicine ; R
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: A Clinical Decision Support System for the Diagnosis, Fracture Risks and Treatment of Osteoporosis

    Bjarni V. Halldorsson / Aron Hjalti Bjornsson / Haukur Tyr Gudmundsson / Elvar Orn Birgisson / Bjorn Runar Ludviksson / Bjorn Gudbjornsson

    Computational and Mathematical Methods in Medicine, Vol

    2014  Volume 2014

    Keywords Computer applications to medicine. Medical informatics ; R858-859.7 ; Medicine (General) ; R5-920 ; Medicine ; R
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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