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Article: Pretreatment of hypersaline and high-organic wastewater with a three-dimensional electrocatalytic system: a pilot-scale study.

Fang, Chengyi / Xie, Shiwei / Xiao, Tian / Liu, Zhi / Hong, Hui / Gong, Shuyi / Liu, Xixiang

Water science and technology : a journal of the International Association on Water Pollution Research

2024 Volume 89, Issue 3, Page(s) 562–575

Abstract: The three-dimensional electrocatalytic oxidation (3DEO) is a promising electrochemical system in the treatment of refractory wastewater, but still far from large-scale applications. In this work, we prepared 146.5 Kg Ti-Sn-Sb@γ- ... ...

Abstract	The three-dimensional electrocatalytic oxidation (3DEO) is a promising electrochemical system in the treatment of refractory wastewater, but still far from large-scale applications. In this work, we prepared 146.5 Kg Ti-Sn-Sb@γ-Al
MeSH term(s)	Wastewater ; Charcoal ; Sewage ; Adsorption ; Catalysis
Chemical Substances	Wastewater ; Charcoal (16291-96-6) ; Sewage
Language	English
Publishing date	2024-02-15
Publishing country	England
Document type	Journal Article
ZDB-ID	764273-8
ISSN	1996-9732 ; 0273-1223
ISSN (online)	1996-9732
ISSN	0273-1223
DOI	10.2166/wst.2024.018
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Article ; Online: Photoactivated chromophore-corneal cross-linking accelerates corneal healing in fungal keratitis

Shuyi Liu / Shifeng Fang / Lijun Zhang

Systematic Reviews, Vol 12, Iss 1, Pp 1-

an updated meta-analysis

2023 Volume 10

Abstract: Abstract Aim To determine the effectiveness and safety of photoactivated chromophore-corneal cross-linking (PACK-CXL) adjuvant in infectious keratitis by April 5, 2022. Methods We searched randomized controlled trials (RCTs) comparing standard antibiotic ...

Abstract	Abstract Aim To determine the effectiveness and safety of photoactivated chromophore-corneal cross-linking (PACK-CXL) adjuvant in infectious keratitis by April 5, 2022. Methods We searched randomized controlled trials (RCTs) comparing standard antibiotic treatment (SAT) plus PACK-CXL to SAT in infectious keratitis in Embase, MEDLINE with PubMed, Web of Science, and Cochrane Library. We independently screened and extracted data using predesigned tables. Cochrane’s risk-of-bias tool was utilized to examine the quality of RCTs. A random-effects model was employed to determine the overall effect size of the meta-analyses. Grading of Recommendations, and Assessment, Development and Evaluations (GRADE) was also performed to examine the quality of evidence. Results Seven eligible RCTs with 283 patients were acquired. Adjuvant PACK-CXL reduced the time needed to perform corneal healing in fungal keratitis (− 1.33 months; 95% CI, − 1.83 to − 0.42, I 2 = 0%, P < 0.05) as compared to SAT alone. The risks of adverse events were not significantly different both in fungal and bacterial keratitis. Due to the substantial heterogeneity among studies, such as population, the type and severity of infectious keratitis, drug regimens of SAT, PACK-CXL protocol, and the judgment of subjective outcomes, the evidence grade was low. Conclusion Adjuvant PACK-CXL accelerates fungal keratitis healing as compared to SAT alone. But more rigorous RCTs are required to determine the clinical effectiveness and safety.
Keywords	PACK-CXL ; Keratitis ; Infection ; Meta-analysis ; Systematic review ; Medicine ; R
Subject code	630
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
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Article ; Online: Photoactivated chromophore-corneal cross-linking accelerates corneal healing in fungal keratitis: an updated meta-analysis.

Liu, Shuyi / Fang, Shifeng / Zhang, Lijun

Systematic reviews

2023 Volume 12, Issue 1, Page(s) 208

Abstract: Aim: To determine the effectiveness and safety of photoactivated chromophore-corneal cross-linking (PACK-CXL) adjuvant in infectious keratitis by April 5, 2022.: Methods: We searched randomized controlled trials (RCTs) comparing standard antibiotic ... ...

Abstract	Aim: To determine the effectiveness and safety of photoactivated chromophore-corneal cross-linking (PACK-CXL) adjuvant in infectious keratitis by April 5, 2022. Methods: We searched randomized controlled trials (RCTs) comparing standard antibiotic treatment (SAT) plus PACK-CXL to SAT in infectious keratitis in Embase, MEDLINE with PubMed, Web of Science, and Cochrane Library. We independently screened and extracted data using predesigned tables. Cochrane's risk-of-bias tool was utilized to examine the quality of RCTs. A random-effects model was employed to determine the overall effect size of the meta-analyses. Grading of Recommendations, and Assessment, Development and Evaluations (GRADE) was also performed to examine the quality of evidence. Results: Seven eligible RCTs with 283 patients were acquired. Adjuvant PACK-CXL reduced the time needed to perform corneal healing in fungal keratitis (- 1.33 months; 95% CI, - 1.83 to - 0.42, I Conclusion: Adjuvant PACK-CXL accelerates fungal keratitis healing as compared to SAT alone. But more rigorous RCTs are required to determine the clinical effectiveness and safety.
MeSH term(s)	Humans ; Corneal Cross-Linking ; Photosensitizing Agents/therapeutic use ; Riboflavin/pharmacology ; Riboflavin/therapeutic use ; Collagen/therapeutic use ; Keratitis/drug therapy ; Keratitis/microbiology ; Anti-Bacterial Agents/therapeutic use
Chemical Substances	Photosensitizing Agents ; Riboflavin (TLM2976OFR) ; Collagen (9007-34-5) ; Anti-Bacterial Agents
Language	English
Publishing date	2023-11-11
Publishing country	England
Document type	Meta-Analysis ; Journal Article ; Review
ZDB-ID	2662257-9
ISSN	2046-4053 ; 2046-4053
ISSN (online)	2046-4053
ISSN	2046-4053
DOI	10.1186/s13643-023-02380-5
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Article ; Online: Dihydromyricetin reverses capecitabine-induced peripheral myelin dysfunction through modulation of oxidative stress.

Fang, Jie / Lou, Shuyi / Zhou, Xinyi / Lou, Dayong / Zhou, Liqin / Bian, Rong

Clinical and experimental pharmacology & physiology

2024 Volume 51, Issue 3, Page(s) e13833

Abstract: Previous clinical reports have shown that capecitabine, an oral prodrug of 5-fluorouracil (5-Fu), can induce peripheral neuropathy, resulting in numbness, paresthesia and hypoesthesia. However, the mechanism through which capecitabine causes peripheral ... ...

Abstract	Previous clinical reports have shown that capecitabine, an oral prodrug of 5-fluorouracil (5-Fu), can induce peripheral neuropathy, resulting in numbness, paresthesia and hypoesthesia. However, the mechanism through which capecitabine causes peripheral nerve injury remains unclear. Here, we demonstrate that systemic administration of capecitabine leads to myelin abnormalities in the peripheral nerves of mice, which are possibly attributed to the death of Schwann cells, the myelinating cells in the peripheral nervous system. Furthermore, our results show that 5-Fu induces significant oxidative stress in Schwann cells by inhibiting the expression of the anti-oxidative protein DJ-1, leading to a decrease in Schwann cell markers. We found that the anti-oxidant dihydromyricetin (DMY) reverses 5-Fu-induced Schwann cell death and oxidative stress and alleviates capecitabine-induced myelin abnormalities. Taken together, our data indicate that capecitabine induces peripheral myelin dysfunction by regulating DJ-1-mediated oxidative stress in Schwann cells and reveal DMY as a potential therapeutic strategy for capecitabine-induced peripheral neuropathy.
MeSH term(s)	Mice ; Animals ; Myelin Sheath/metabolism ; Capecitabine/metabolism ; Oxidative Stress ; Peripheral Nervous System Diseases/metabolism ; Fluorouracil/toxicity ; Flavonols
Chemical Substances	Capecitabine (6804DJ8Z9U) ; dihydromyricetin (KD8QND6427) ; Fluorouracil (U3P01618RT) ; Flavonols
Language	English
Publishing date	2024-01-30
Publishing country	Australia
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	189277-0
ISSN	1440-1681 ; 0305-1870 ; 0143-9294
ISSN (online)	1440-1681
ISSN	0305-1870 ; 0143-9294
DOI	10.1111/1440-1681.13833
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Article ; Online: Risk of dry eye in headache patients: a systematic review and meta-analysis.

Liu, Shuyi / Dong, He / Fang, Shifeng / Zhang, Lijun

Annals of medicine

2022 Volume 54, Issue 1, Page(s) 2876–2885

Abstract: Objectives: The objective of this meta-analysis was to identify whether headache increase the risk of dry eye disease (DED).: Methods: PubMed, Web of Science, Cochrane Library and EMBASE databases were searched for relevant studies. The odds ratio ( ... ...

Abstract	Objectives: The objective of this meta-analysis was to identify whether headache increase the risk of dry eye disease (DED). Methods: PubMed, Web of Science, Cochrane Library and EMBASE databases were searched for relevant studies. The odds ratio (OR) of DED in all-cause headache was calculated Results: This meta-analysis included 11 studies. Pooled analysis indicated that all-cause headache was related to a higher risk of DED (OR = 1.586, 95% CI : 1.409-1.785, Conclusions: This study indicates that headache is related to a higher risk of DED, especially in the migraine patients. These results suggest that headaches should be regarded as an independent risk factor for DED.KEY MESSAGESIn this meta-analysis, 11 studies (one cohort study, four case-control studies and six cross-sectional studies) covering 3,575,957 individuals were included.Pooled analysis indicated that all-cause headache was related to a higher risk of dry eye (OR = 1.586, 95% CI: 1.409-1.785,
MeSH term(s)	Humans ; Cross-Sectional Studies ; Cohort Studies ; Dry Eye Syndromes/epidemiology ; Dry Eye Syndromes/etiology ; Headache ; Migraine Disorders/epidemiology
Language	English
Publishing date	2022-10-19
Publishing country	England
Document type	Meta-Analysis ; Systematic Review
ZDB-ID	1004226-x
ISSN	1365-2060 ; 1651-2219 ; 0785-3890 ; 1743-1387
ISSN (online)	1365-2060 ; 1651-2219
ISSN	0785-3890 ; 1743-1387
DOI	10.1080/07853890.2022.2133165
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Zs.A 680: Show issues

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Article ; Online: Pulmonary inflammation caused by cigarette smoke combined with lipopolysaccharide up-regulated OATP2B1 in rat lung tissue and pulmonary epithelial cells.

Wang, Zihao / Fang, Xin / Zhang, Shuyi / Song, Jue

Experimental lung research

2022 Volume 48, Issue 3, Page(s) 114–125

Abstract: Organic anion transport polypeptide 2B1 (OATP2B1), as an uptake transporter, is involved in the transport of many related substrate drugs and endogenous substances in the lungs. A large amount of data shows that cigarette smoke plays an important role in ...

Abstract	Organic anion transport polypeptide 2B1 (OATP2B1), as an uptake transporter, is involved in the transport of many related substrate drugs and endogenous substances in the lungs. A large amount of data shows that cigarette smoke plays an important role in the occurrence and development of lung diseases such as chronic obstructive pulmonary disease (COPD), asthma and bronchitis. However, the effect of cigarette smoke combined with lipopolysaccharide-induced pulmonary inflammation on the expression of OATP2B1 is not clear. In this study, we used cigarette smoke combined with lipopolysaccharide to establish a lung inflammation model in vivo and in vitro to explore the effect of inflammation on the expression of OATP2B1. Our study found that cigarette smoke combined with lipopolysaccharide-induced pulmonary inflammation upregulated the mRNA and protein expression of OATP2B1 and related inflammatory factors, and the expression level of related proteins was higher with the aggravation of inflammation. The experimental results of animals in vivo were consistent with those of cells in vitro. In summary, these findings provide a model and basis for a follow-up study of the mechanism of OATP2B1 in pulmonary inflammation.
MeSH term(s)	Animals ; Cigarette Smoking ; Epithelial Cells/metabolism ; Follow-Up Studies ; Inflammation/metabolism ; Lipopolysaccharides ; Lung/metabolism ; Organic Anion Transporters/metabolism ; Organic Anion Transporters/pharmacology ; Pneumonia/chemically induced ; Pneumonia/metabolism ; Pulmonary Disease, Chronic Obstructive/metabolism ; Rats ; Nicotiana
Chemical Substances	Lipopolysaccharides ; Organic Anion Transporters ; oatp2b1 protein, rat
Language	English
Publishing date	2022-04-20
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	603791-4
ISSN	1521-0499 ; 0190-2148
ISSN (online)	1521-0499
ISSN	0190-2148
DOI	10.1080/01902148.2022.2066223
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Article ; Online: Flexible and Generalized Real Photograph Denoising Exploiting Dual Meta Attention.

Ma, Ruijun / Li, Shuyi / Zhang, Bob / Fang, Leyuan / Li, Zhengming

IEEE transactions on cybernetics

2023 Volume 53, Issue 10, Page(s) 6395–6407

Abstract: Supervised deep learning techniques have been widely explored in real photograph denoising and achieved noticeable performances. However, being subject to specific training data, most current image denoising algorithms can easily be restricted to certain ...

Abstract	Supervised deep learning techniques have been widely explored in real photograph denoising and achieved noticeable performances. However, being subject to specific training data, most current image denoising algorithms can easily be restricted to certain noisy types and exhibit poor generalizability across testing sets. To address this issue, we propose a novel flexible and well-generalized approach, coined as dual meta attention network (DMANet). The DMANet is mainly composed of a cascade of the self-meta attention blocks (SMABs) and collaborative-meta attention blocks (CMABs). These two blocks have two forms of advantages. First, they simultaneously take both spatial and channel attention into account, allowing our model to better exploit more informative feature interdependencies. Second, the attention blocks are embedded with the meta-subnetwork, which is based on metalearning and supports dynamic weight generation. Such a scheme can provide a beneficial means for self and collaborative updating of the attention maps on-the-fly. Instead of directly stacking the SMABs and CMABs to form a deep network architecture, we further devise a three-stage learning framework, where different blocks are utilized for each feature extraction stage according to the individual characteristics of SMAB and CMAB. On five real datasets, we demonstrate the superiority of our approach against the state of the art. Unlike most existing image denoising algorithms, our DMANet not only possesses a good generalization capability but can also be flexibly used to cope with the unknown and complex real noises, making it highly competitive for practical applications.
Language	English
Publishing date	2023-09-15
Publishing country	United States
Document type	Journal Article
ISSN	2168-2275
ISSN (online)	2168-2275
DOI	10.1109/TCYB.2022.3170472
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Article: The role and mechanism of NLRP3 inflammasome-mediated astrocyte activation in dehydrocorydaline against CUMS-induced depression.

Fang, Yu / Guo, Hong / Wang, Qiannan / Liu, Congcong / Ge, Shuyi / Yan, Bohua

Frontiers in pharmacology

2022 Volume 13, Page(s) 1008249

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2022-11-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2022.1008249
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Article ; Online: Corrigendum to "FUNDC1 insufficiency sensitizes high fat diet intake-induced cardiac remodeling and contractile anomaly through ACSL4-mediated ferroptosis" [Metabolism 122 (September 2021) 154840].

Pei, Zhaohui / Liu, Yandong / Liu, Suqin / Jin, Wei / Luo, Yuanfei / Sun, Mingming / Duan, Yu / Ajoolabady, Amir / Sowers, James R / Fang, Yan / Cao, Feng / Xu, Haixia / Bi, Yaguang / Wang, Shuyi / Ren, Jun

Metabolism: clinical and experimental

2024 Volume 155, Page(s) 155918

Language	English
Publishing date	2024-04-20
Publishing country	United States
Document type	Published Erratum
ZDB-ID	80230-x
ISSN	1532-8600 ; 0026-0495
ISSN (online)	1532-8600
ISSN	0026-0495
DOI	10.1016/j.metabol.2024.155918
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Article ; Online: Sleep disturbance and psychotic-like experiences among urban adolescents with and without parental migration.

Wang, Dongfang / Ma, Zijuan / Zhai, Shuyi / Sun, Meng / Fan, Fang

Frontiers in public health

2023 Volume 10, Page(s) 1037963

Abstract: Aim: Sleep disturbance was closely associated with an increased risk of psychotic-like experiences (PLEs). This study aims to explore the association between sleep disturbance and PLEs among urban adolescents with and without parental migration.: ... ...

Abstract	Aim: Sleep disturbance was closely associated with an increased risk of psychotic-like experiences (PLEs). This study aims to explore the association between sleep disturbance and PLEs among urban adolescents with and without parental migration. Methods: A total of 67, 532 urban Chinese adolescents were recruited in a large web-based survey during April 21st to May 12th, 2021. In our study, sleep disturbance, PLEs, family function, school climate, and a series of socio-demographic were assessed. And hierarchical logistic regression analyses were performed to examine influential factors associated with PLEs. Results: Urban left-behind children (LBC) had a higher prevalence of sleep disturbance and PLEs than non-LBC. After controlling for confounders, parental migration was associated to PLEs with weak significance (OR = 1.19). Meanwhile, sleep disturbance was found to be a robust risk factor for PLEs (OR = 3.84 and 4.09), with or without the effect of parental migration. In addition, better family function and school climate has significant association with decreased risk of PLEs. Conclusion: Adolescents with sleep disturbance are more likely to report PLEs. Adolescents' PLEs preventive strategies could focus on reducing sleep disturbance related symptoms as well as improving family function and school climate.
MeSH term(s)	Child ; Humans ; Adolescent ; Psychotic Disorders/epidemiology ; Psychotic Disorders/diagnosis ; Sleep Wake Disorders/epidemiology ; Surveys and Questionnaires ; Risk Factors ; Sleep
Language	English
Publishing date	2023-01-04
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.1037963
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