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  1. Article: Erratum to "IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper" [World Allergy Organ J 13/2 (2020) 100080].

    Ansotegui, Ignacio J / Melioli, Giovanni / Canonica, Giorgio Walter / Caraballo, Luis / Villa, Elisa / Ebisawa, Motohiro / Passalacqua, Giovanni / Savi, Eleonora / Ebo, Didier / Gómez, R Maximiliano / Luengo Sánchez, Olga / Oppenheimer, John J / Jensen-Jarolim, Erika / Fischer, David A / Haahtela, Tari / Antila, Martti / Bousquet, Jean J / Cardona, Victoria / Chiang, Wen Chin /
    Demoly, Pascal M / DuBuske, Lawrence M / Ferrer Puga, Marta / Gerth van Wijk, Roy / González Díaz, Sandra Nora / Gonzalez-Estrada, Alexei / Jares, Edgardo / Kalpaklioğlu, Ayse Füsun / Kase Tanno, Luciana / Kowalski, Marek L / Ledford, Dennis K / Monge Ortega, Olga Patricia / Morais-Almeida, Mário / Pfaar, Oliver / Poulsen, Lars K / Pawankar, Ruby / Renz, Harald E / Romano, Antonino G / Rosário Filho, Nelson A / Rosenwasser, Lanny / Sánchez Borges, Mario A / Scala, Enrico / Senna, Gian-Enrico / Sisul, Juan Carlos / Tang, Mimi L K / Yu-Hor Thong, Bernard / Valenta, Rudolf / Wood, Robert A / Zuberbier, Torsten

    The World Allergy Organization journal

    2021  Volume 14, Issue 7, Page(s) 100557

    Abstract: This corrects the article DOI: 10.1016/j.waojou.2019.100080.]. ...

    Abstract [This corrects the article DOI: 10.1016/j.waojou.2019.100080.].
    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2581968-9
    ISSN 1939-4551
    ISSN 1939-4551
    DOI 10.1016/j.waojou.2021.100557
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  2. Article: Hypoallergenic fragment of Par j 2 increases functional expression of Toll-like receptors in atopic children.

    Pace, E / Duro, G / La Grutta, S / Ferraro, M / Bruno, A / Bousquet, J / Bonsignore, G / Gjomarkaj, M

    Allergy

    2006  Volume 61, Issue 12, Page(s) 1459–1466

    Abstract: Background: Parietaria judaica (Par j) is one of the main causes of allergy ... j 2 (rPar j 2) and of its fragments (1-55 and 52-102) on atopic children.: Methods: We used skin ... the effect of rPar j 2 and of the two fragments on neutrophil chemotaxis, on CD45RO, on TLR2 and TLR4 ...

    Abstract Background: Parietaria judaica (Par j) is one of the main causes of allergy in the Mediterranean countries. The activation of Toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS) inhibits nasal inflammation of atopic children.
    Objective: To examine, in vivo and in vitro, the effect of recombinant Par j 2 (rPar j 2) and of its fragments (1-55 and 52-102) on atopic children.
    Methods: We used skin prick test for in vivo evaluations. We assessed, in vitro, in peripheral blood mononuclear cells (PBMC), the effect of rPar j 2 and of the two fragments on neutrophil chemotaxis, on CD45RO, on TLR2 and TLR4 expression, on LPS binding and on interferon (IFN)-gamma release, by a microchemotaxis chamber, by flow cytometry and by enzyme-linked immunosorbent assay, respectively.
    Results: In vivo while rPar j 2 induced a positive skin reaction, 1-55 and 52-102 fragments did not. In vitro, while rPar j 2 increased both CD45RO expression and neutrophils chemotaxis in PBMC, both Par j 2 fragments did not. 1-55 fragment of Par j 2 upregulated both TLR2 and TLR4 expression and LPS binding, while the rPar j 2 and 52-102 fragment did not. Finally, 1-55 fragment of Par j 2 induced IFNgamma release, while the rPar j 2 and 52-102 fragment did not.
    Conclusions: Hypoallergenic 1-55 fragment, upregulating innate immunity receptors and increasing IFNgamma, might re-orientate, in atopics, the immune system toward a physiologic balance between Th1 and Th2 responses.
    MeSH term(s) Adolescent ; Allergens/physiology ; Child ; Female ; Humans ; Hypersensitivity, Immediate/metabolism ; Male ; Peptide Fragments/physiology ; Plant Proteins/physiology ; Toll-Like Receptors/biosynthesis ; Toll-Like Receptors/genetics
    Chemical Substances Allergens ; Par j 2 allergen, Parietaria ; Peptide Fragments ; Plant Proteins ; Toll-Like Receptors
    Language English
    Publishing date 2006-12
    Publishing country Denmark
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/j.1398-9995.2006.01234.x
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  3. Article: CME. Zertifizierte Fortbildung. Visual analogue scales (VAS) - Measuring instruments for the documentation of Symptoms and therapy monitoring in case of allergic rhinitis in everyday health care. Allergo J Int 2017;26:16-24. Visuelle Analogskalen (VAS) als Messinstrumente zur Dokumentation der Symptomatik und Therapiekontrolle einer allergischen Rhinitis in der Routineversorgung

    Klimek, L. / Bergmann, K.- C. / Biedermann, T. / Bousquet, J. / Hellings, P. / Jung, K. / Merk, H. / Olze, H. / Schlenter, W. / Stock, P. / Ring, J. / Wagenmann, M. / Wehrmann, W. / Mösges, R. / Pfaar, O.

    Allergo-Journal

    2017  Volume 26, Issue 1, Page(s) 36

    Language German
    Document type Article
    ZDB-ID 1136943-7
    ISSN 0941-8849
    Database Current Contents Medicine

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  4. Book ; Online: Rhinitis associated with asthma is distinct from rhinitis alone

    Bousquet, Jean

    The ARIA-MeDALL hypothesis

    2023  

    Abstract: 1169 ... 1203 ... Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between ...

    Abstract 1169

    1203

    Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the “Epithelial Barrier Hypothesis.” This review determined that the “one-airway-one-disease” concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme “allergic” (asthma) phenotype combining asthma, rhinitis, and conjunctivitis. Rhinitis alone and rhinitis and asthma multimorbidity represent two distinct diseases with the following differences: (i) genomic and transcriptomic background (Toll-Like Receptors and IL-17 for rhinitis alone as a local disease; IL-33 and IL-5 for allergic and non-allergic multimorbidity as a systemic disease), (ii) allergen sensitization patterns (mono- or pauci-sensitization versus polysensitization), (iii) severity of symptoms, and (iv) treatment response. In conclusion, rhinitis alone (local disease) and rhinitis with asthma multimorbidity (systemic disease) should be considered as two distinct diseases, possibly modulated by the microbiome, and may be a model for understanding the epidemics of chronic and autoimmune diseases.

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    Keywords asthma ; IL-33 ; multimorbidity ; rhinitis ; Toll-like receptors
    Subject code 610
    Language English
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Après un cancer : séquelles, retour à l’emploi et droit à l’oubli.

    Foucaud, Jérôme / Bousquet, Philippe-Jean

    La Revue du praticien

    2024  Volume 74, Issue 1, Page(s) 48–51

    Abstract: After cancer: AFTER-EFFECTS. RETURN TO WORK AND THE RIGHT TO FORGET. The ten-year strategy 2021-2030 against cancers makes staying at work or returning to work after cancer a major priority. A growing number of patients are on the job market at the time ...

    Title translation After cancer: after-eff ects, return to work and the right to forget.
    Abstract After cancer: AFTER-EFFECTS. RETURN TO WORK AND THE RIGHT TO FORGET. The ten-year strategy 2021-2030 against cancers makes staying at work or returning to work after cancer a major priority. A growing number of patients are on the job market at the time of their cancer diagnosis, with a potentially long career future. The after-effects of the disease, and the gap between them and the professional world, present them with numerous difficulties. French national cancer institute (INCa) has launched several initiatives to help people stay in work and return to work, in particular to complement the measures developed by the League against Cancer. INCa has set up the «Cancer and Employment» Business Club, a forum for the exchange of best practices and experiences between employers and researchers in the human and social sciences. The «Cancer aide info réseau entrepreneur» (CAIRE) scheme supports self-employed patients in their professional careers, and gives them a voice in their professional ecosystem. Research initiatives are also undertaken. The social repercussions of the disease also include its impact on borrowing capacity, for both personal and business loans. The "right to be forgotten" for cancer sufferers applies 5 years after the end of the therapeutic protocol. A grid completes the system, and in certain cases enables insurances for a loan can be obtained on standard or similar terms, even before this period has elapsed. It also includes other pathologies such as HIV, hepatitis C and cystic fibrosis. Last but not least, health questionnaires have been abolished for loans under €200,000. The role of the health professional is paramount, providing advice and facilitating the completion of documents requested by insurers.
    MeSH term(s) Humans ; Employment ; Neoplasms/epidemiology ; Neoplasms/therapy ; Return to Work
    Language French
    Publishing date 2024-02-08
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 205365-2
    ISSN 2101-017X ; 0035-2640
    ISSN (online) 2101-017X
    ISSN 0035-2640
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  6. Article ; Online: Rhinitis phenotypes based on multimorbidities.

    Cruz, Álvaro A / Bousquet, Jean

    The journal of allergy and clinical immunology. In practice

    2024  

    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2024.04.013
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  7. Article ; Online: Nose Woes.

    Naclerio, Robert / Bousquet, Jean

    The journal of allergy and clinical immunology. In practice

    2024  

    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2024.04.020
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  8. Article: Correction to: Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma.

    Bousquet, J

    Clinical and translational allergy

    2019  Volume 9, Page(s) 52

    Abstract: This corrects the article DOI: 10.1186/s13601-019-0252-0.]. ...

    Abstract [This corrects the article DOI: 10.1186/s13601-019-0252-0.].
    Language English
    Publishing date 2019-10-09
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2630865-4
    ISSN 2045-7022
    ISSN 2045-7022
    DOI 10.1186/s13601-019-0291-6
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  9. Article: Correction to: MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence.

    Bousquet, J

    Clinical and translational allergy

    2019  Volume 9, Page(s) 51

    Abstract: This corrects the article DOI: 10.1186/s13601-018-0227-6.]. ...

    Abstract [This corrects the article DOI: 10.1186/s13601-018-0227-6.].
    Language English
    Publishing date 2019-10-09
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2630865-4
    ISSN 2045-7022
    ISSN 2045-7022
    DOI 10.1186/s13601-019-0290-7
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  10. Article ; Online: Staphylococcus aureus Enterotoxin Sensitization Without Aeroallergen Sensitization: An Important Severe Asthma Phenotype.

    Navanandan, Nidhya / Bousquet, Jean

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 10, Page(s) 3062–3063

    MeSH term(s) Humans ; Staphylococcus aureus ; Asthma/epidemiology ; Allergens ; Enterotoxins ; Phenotype
    Chemical Substances Allergens ; Enterotoxins
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.08.005
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