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  1. Article ; Online: A graft-free scleral sleeve technique of Ahmed Glaucoma Valve implantation in refractory glaucoma- Rising to the challenge of COVID-19 pandemic.

    Gupta, Richa

    Indian journal of ophthalmology

    2021  Volume 69, Issue 6, Page(s) 1623–1625

    Abstract: We describe a case of 63-year-old woman, with primary open-angle glaucoma (POAG) who presented to us in the COVID era with uncontrolled intraocular pressure (IOP) on maximum medical therapy (MMT) in the right eye (OD), previously operated twice for ... ...

    Abstract We describe a case of 63-year-old woman, with primary open-angle glaucoma (POAG) who presented to us in the COVID era with uncontrolled intraocular pressure (IOP) on maximum medical therapy (MMT) in the right eye (OD), previously operated twice for trabeculectomy in (OD), and once in left eye (OS). A modified graft-free surgical technique of inserting the Ahmed Glaucoma valve (AGV) tube through a scleral sleeve was employed. Visual acuity and IOP remained stable during 6-month follow-up period.
    MeSH term(s) COVID-19 ; Female ; Follow-Up Studies ; Glaucoma/surgery ; Glaucoma Drainage Implants ; Humans ; Intraocular Pressure ; Middle Aged ; Pandemics ; Postoperative Complications ; Prosthesis Implantation ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome
    Language English
    Publishing date 2021-05-19
    Publishing country India
    Document type Case Reports
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_3654_20
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  2. Article ; Online: Author reply: Intricate clinical evaluation and management strategies in vision-threatening phacomorphic glaucoma.

    Gupta, Richa / Chauhan, Lokesh

    Taiwan journal of ophthalmology

    2023  Volume 13, Issue 2, Page(s) 261–262

    Language English
    Publishing date 2023-06-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 2652841-1
    ISSN 2211-5072 ; 2211-5072
    ISSN (online) 2211-5072
    ISSN 2211-5072
    DOI 10.4103/tjo.TJO-D-22-00068
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  3. Article ; Online: The Politics of Space and Heterotopia in the Works of W. G. Sebald

    Richa Gupta

    IAFOR Journal of Literature & Librarianship, Vol 8, Iss 1, Pp 51-

    2019  Volume 65

    Abstract: This paper will attempt to read how history and space are informed and transformed by each other specifically in the prose narratives of the German writer, W. G. Sebald. In the course of reproducing history in a non-synoptic manner in these prose ... ...

    Abstract This paper will attempt to read how history and space are informed and transformed by each other specifically in the prose narratives of the German writer, W. G. Sebald. In the course of reproducing history in a non-synoptic manner in these prose narratives, there are several ways in which space and history are connected with each other. This paper will explore these myriad relations and connections between space and history. Drawing from these links, the paper will go on to demonstrate how various incompatible elements of history and space are juxtaposed on one particular site creating a heterotopia. Sebald’s innovative fiction is exceptional in its narrative technique, employment of sources and incorporation of the multiple points of views of the narrators along with their interlocutors. The specific mode of narration Sebald employs, this paper contends, treats neither space nor history as foundational categories but instead tries to posit a historico-geographical framework within which many volatile moments of heterotopia develop. The paper begins with an analysis of how history and its constituent, memory, are related to space and spatial encounters. Having established the nexus between these two categories, it goes on to examine how Sebald’s narratives offer a critique of cartographic space and how identities are established through a politics of space. All these arguments culminate to demonstrate that these narratives are constituted by heterotopic moments due to the juxtapositions and multiplicities that arise from the historico-geographical scheme Sebald brings into play.
    Keywords history ; space ; heterotopia ; w.g. sebald ; prose narrative ; Bibliography. Library science. Information resources ; Z
    Subject code 820
    Language English
    Publishing date 2019-12-01T00:00:00Z
    Publisher The International Academic Forum
    Document type Article ; Online
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  4. Article ; Online: Outcomes of living donor liver transplantation for patients with APASL defined-acute-on-chronic liver failure.

    Singh, Shweta A / Bhargava, Richa / Gupta, Subhash

    Hepatology international

    2023  Volume 18, Issue 1, Page(s) 294–295

    MeSH term(s) Humans ; Liver Transplantation ; Acute-On-Chronic Liver Failure/surgery ; Living Donors
    Language English
    Publishing date 2023-10-09
    Publishing country United States
    Document type Letter
    ZDB-ID 2270316-0
    ISSN 1936-0541 ; 1936-0533
    ISSN (online) 1936-0541
    ISSN 1936-0533
    DOI 10.1007/s12072-023-10589-8
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  5. Article ; Online: A serious warning: A case report on localized amyloidosis of the oral cavity.

    John, Sharon / Subba, Priyambadha / Aramugam, Aravindhan / Gupta, Shalini / Khanna, Richa

    Indian journal of pathology & microbiology

    2024  

    Abstract: Abstract: Amyloidosis is a relatively rare condition with an array of complex pathophysiology. Localized amyloidosis is a rare and benign condition that practically never results in any clinical repercussions in the head and neck area. Multiple soft ... ...

    Abstract Abstract: Amyloidosis is a relatively rare condition with an array of complex pathophysiology. Localized amyloidosis is a rare and benign condition that practically never results in any clinical repercussions in the head and neck area. Multiple soft nodules of the tongue, lip, and cheek are the most commonly described defining characteristics of localized oral amyloidosis. These nodules originate due to the proliferation of abnormally folded protein aggregates in the body's extracellular tissue compartments, which destroy organ structure and function. Herein, we address the case of a female infant aged one with a smooth nodule in the labial mucosa who was diagnosed with primary localized amyloidosis. When a patient is diagnosed with amyloidosis of the oral mucosa, the possibility of systemic amyloidosis or an underlying plasma cell dyscrasia must be ruled out. Surgical treatment may be beneficial for eliminating any functional impairment if primary localized amyloidosis is established.
    Language English
    Publishing date 2024-02-19
    Publishing country India
    Document type Journal Article
    ZDB-ID 197621-7
    ISSN 0974-5130 ; 0377-4929
    ISSN (online) 0974-5130
    ISSN 0377-4929
    DOI 10.4103/ijpm.ijpm_720_23
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  6. Article ; Online: Development and optimization of

    Jain, Richa / Singh, Ruchi / Badhwar, Reena / Gupta, Tinku / Popli, Harvinder

    Drug development and industrial pharmacy

    2024  Volume 50, Issue 3, Page(s) 181–191

    Abstract: Objective: The present research deals with sequential optimization strategy based on Central Composite Design to optimize the process variables for efficient production of : Methods: Two substantial factors influencing the dependent variables viz UV- ... ...

    Abstract Objective: The present research deals with sequential optimization strategy based on Central Composite Design to optimize the process variables for efficient production of
    Methods: Two substantial factors influencing the dependent variables viz UV-visible absorbance, particle size, zeta potential and polydispersity index (PDI) were identified as NaOH concentration, RH concentration, temperature as independent variables.
    Results: The particles size (114 nm), PDI (0.45), and zeta potential (-29.5 mV) of optimized formulation were found, respectively.
    Conclusions: The prepared CLT-AgNPs gel can be as a potential substitute in the management and treatment of acute and chronic wounds.
    MeSH term(s) Silver ; Metal Nanoparticles ; Clitoria ; Nanogels ; Wound Healing ; Anti-Bacterial Agents/pharmacology ; Polyethylene Glycols ; Polyethyleneimine
    Chemical Substances Silver (3M4G523W1G) ; polyethylene glycol polyethyleneimine nanogel ; Nanogels ; Anti-Bacterial Agents ; Polyethylene Glycols (3WJQ0SDW1A) ; Polyethyleneimine (9002-98-6)
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 751874-2
    ISSN 1520-5762 ; 0363-9045
    ISSN (online) 1520-5762
    ISSN 0363-9045
    DOI 10.1080/03639045.2024.2308043
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  7. Article ; Online: Acute-Onset Neuromuscular Paralysis in Children- Do not forget to Rule Out Snake Bite.

    Jeenwal, Pragati / Gupta, Juhi / Choudhary, Richa / Meena, Pradeep / Sehra, R N / Devpura, Kusum

    Neurology India

    2024  Volume 72, Issue 1, Page(s) 189–190

    MeSH term(s) Child ; Humans ; Snake Bites/complications
    Language English
    Publishing date 2024-02-29
    Publishing country India
    Document type Journal Article
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/neurol-india.Neurol-India-D-24-00079
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  8. Article ; Online: p16INK4a and γ-H2AX as Biomarkers of Senescence in Skin Tissue

    Richa Gupta / Anjali Aggarwal / Tulika Gupta / Chiman Kumari

    Journal of Clinical and Diagnostic Research, Vol 17, Iss 10, Pp 05-

    A Cadaveric Cross-sectional Study at a Tertiary Care Centre in Punjab, India

    2023  Volume 10

    Abstract: Introduction: Baseline expression of p16INK4a characterises cellular senescence. Similarly, the measurement of γ-GammaH2AX (γ-H2AX) foci levels in cells provides a reliable method for quantification of Deoxyribonucleic Acid (DNA) damage. Aim: To explore ... ...

    Abstract Introduction: Baseline expression of p16INK4a characterises cellular senescence. Similarly, the measurement of γ-GammaH2AX (γ-H2AX) foci levels in cells provides a reliable method for quantification of Deoxyribonucleic Acid (DNA) damage. Aim: To explore the role of p16INK4a and γ-H2AX as biomarkers of senescence in skin tissue. Materials and Methods: This was a cross-sectional study conducted in the Department of Anatomy, PGIMER, Chandigarh, Punjab, India from June 2022 to January 2023. Skin tissue was obtained from 30 cadavers, aged 20-90 years, from the anterior abdominal wall. The time duration of sample collection after death varied from six hours to 12 hours. Samples were divided into two groups: Group-I <30 years and Group-II >70 years, with n=15 in each group. The relative change in the expression pattern of p16INK4a and γH2AX markers, as well as the microstructure of the skin (thickness of epidermis and dermis, distribution of collagen I/II/III fibres, architecture of sebaceous glands), were statistically analysed using an unpaired t-test. Results: Intense staining was observed with p16INK4a in Group-II, showing positivity in 60.75% of the cells, while Group-I depicted a weak staining pattern (15%). On immunostaining with γ-H2AX, only Group-II cells showed intense positivity (45%). Significant differences were observed in the epidermal and dermal thickness: Group-I (165.5267±37.73 μm; 2394.6±874.13 μm); Group-II (54.6±22.79 μm; 566.67±242.23 μm), and collagen Type-II/III fibres were found predominantly in aging skin tissue. Conclusion: The present study provides comprehensive data regarding age-associated changes between p16INK4a, γ-H2AX, and skin microstructure, which result in decreased repair and regenerative capacity of skin tissue and various age-related skin diseases.
    Keywords aging ; deoxyribonucleic acid damage ; histology ; regenerative ; skin diseases ; Medicine ; R
    Subject code 571
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
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  9. Article: Food Insecurity and its Association with Dietary Diversity: A Cross-Sectional Study in Rural Households in Jammu.

    Langer, Bhavna / Gupta, Rajiv Kumar / Kumari, Rashmi / Mahajan, Richa

    Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine

    2024  Volume 49, Issue 1, Page(s) 70–75

    Abstract: ... to enhance protein rich diet. ...

    Abstract Background: Food insecurity is a matter of public health concern as it is associated with adverse health outcomes particularly among vulnerable population. Accessibility and availability of nutritious and culturally appropriate food is paramount to achieve zero hunger. To assess the prevalence of household food insecurity, to estimate the household dietary diversity and its association with household food insecurity.
    Material and methods: Using multistage sampling 381 rural households were surveyed. Household Food Insecurity Access Scale and House hold Dietary Diversity Scale were used as study instruments. Chi square test was used to compare the two groups and
    Results: Prevalence of household insecurity was 33.3% (127) among the surveyed households and 8.1% (31) had severe food insecurity. The mean HFIS score was 6.85 ± 4.82. The household Dietary diversity score was 8.14 ± 1.54 for food secure and 6.51 ± 1.38 for severely food insecure households. There was a statistically significant difference in intake of milk and milk products, fruits, eggs and meat/poultry among food secure and insecure households (
    Conclusion: Food insecurity was high in rural households and was associated with lower dietary intake of foods from protein group, necessitating a need to reinforce the food security programmes in rural India with focus to enhance protein rich diet.
    Language English
    Publishing date 2024-01-12
    Publishing country India
    Document type Journal Article
    ZDB-ID 2085330-0
    ISSN 1998-3581 ; 0970-0218
    ISSN (online) 1998-3581
    ISSN 0970-0218
    DOI 10.4103/ijcm.ijcm_811_22
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  10. Article ; Online: Distinct subunit architecture and assembly pattern of DNA gyrase from mycobacteria.

    Faheem, Iqball / Gupta, Richa / Nagaraja, Valakunja

    Molecular microbiology

    2023  Volume 119, Issue 6, Page(s) 728–738

    Abstract: DNA gyrase, the sole negative supercoiling type II topoisomerase, is composed of two subunits, GyrA and GyrB, encoded by the gyrA and gyrB genes, respectively, that form a quaternary complex of ... ...

    Abstract DNA gyrase, the sole negative supercoiling type II topoisomerase, is composed of two subunits, GyrA and GyrB, encoded by the gyrA and gyrB genes, respectively, that form a quaternary complex of A
    MeSH term(s) DNA Gyrase/genetics ; DNA Gyrase/metabolism ; Escherichia coli/metabolism ; Mycobacterium tuberculosis/metabolism ; Mycobacterium smegmatis/genetics ; Mycobacterium smegmatis/metabolism ; DNA, Superhelical
    Chemical Substances DNA Gyrase (EC 5.99.1.3) ; DNA, Superhelical
    Language English
    Publishing date 2023-05-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 619315-8
    ISSN 1365-2958 ; 0950-382X
    ISSN (online) 1365-2958
    ISSN 0950-382X
    DOI 10.1111/mmi.15068
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