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Book ; Online ; Thesis: Feasibility studies for the identification of plastics on land surfaces and their functional assignment using optical remote sensing

Zhou, Shanyu Verfasser] / [Zhu, Xiaoxiang [Akademischer Betreuer] / Zhu, Xiaoxiang [Gutachter] / Feilhauer, Hannes [Gutachter] / Rast, Michael [Gutachter]

2023

Author's details	Shanyu Zhou ; Gutachter: Xiaoxiang Zhu, Hannes Feilhauer, Michael Rast ; Betreuer: Xiaoxiang Zhu
Keywords	Geowissenschaften ; Earth Sciences
Subject code	sg550
Language	English
Publisher	Universitätsbibliothek der TU München
Publishing place	München
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

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Article ; Online: Competition Strategy of Online Retailers Considering Service Sensitivity and Cognitive Differences

ZHOU Xiaoxiang, HUANG Chengfeng, LI Hao

Jisuanji kexue yu tansuo, Vol 16, Iss 9, Pp 2096-

2022 Volume 2107

Abstract: In order to analyze the competitive behavior of online retailers in complex market under the environment of diversified customers, a duopoly competition model considering the service sensitivity and cognitive differences is established by using the ... ...

Abstract	In order to analyze the competitive behavior of online retailers in complex market under the environment of diversified customers, a duopoly competition model considering the service sensitivity and cognitive differences is established by using the Hotelling model. The equilibrium price, demand and revenue of static game and dynamic game are solved, and the changing trend is studied by numerical simulation. Results have shown that online retailers' profits are affected by the service sensitivity and cognitive differences, not only related to the price directly, but also relevant to unit service cost, brand cognition and competitors' pricing strategy highly. The high service providers with internet brand cognition have a significant price advantage, which means high service is always accompanied by high prices. Stray price effects exist in online retailers, blind to improve the quality of the cognitive service may do more harm than good for the low quality of service provider. Online retailers have the first-mover advantages. The previous decision maker's equilibrium profit is obviously higher than the latter, as well as the price. The dynamic equilibrium is also significantly better than the static equilibrium on profits and price. Online retailers have sufficient intrinsic motivation to grab the opportunity. There is a theoretical threshold for the service level of online retail, and merchants will not provide services beyond the threshold. Theoretical references can be provided on the pricing competition and service mode selection for online retailers in the context of big data.
Keywords	\|online retailers\|service sensitivity\|cognitive differences\|competition strategy ; Electronic computers. Computer science ; QA75.5-76.95
Subject code	303
Language	Chinese
Publishing date	2022-09-01T00:00:00Z
Publisher	Journal of Computer Engineering and Applications Beijing Co., Ltd., Science Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Spontaneous rupture of the urinary bladder due to binge drinking: A possibly avoidable accident.

Huang, Yanping / Zhou, Zhengxi / Li, Yifan / Wang, Xiaoxiang

Asian journal of surgery

2022 Volume 45, Issue 12, Page(s) 2844–2845

MeSH term(s)	Humans ; Urinary Bladder/diagnostic imaging ; Rupture, Spontaneous/etiology ; Binge Drinking/complications ; Pelvis ; Accidents ; Ethanol
Chemical Substances	Ethanol (3K9958V90M)
Language	English
Publishing date	2022-06-21
Publishing country	China
Document type	Letter
ZDB-ID	1068461-x
ISSN	0219-3108 ; 1015-9584
ISSN (online)	0219-3108
ISSN	1015-9584
DOI	10.1016/j.asjsur.2022.06.061
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Article ; Online: A patient with grade IV renal injury receiving twice extracorporeal shockwave lithotripsy (ESWL) at intervals less than three days.

Zhou, Zhengxi / Dong, Changming / Huang, Yanping / Wang, Xiaoxiang

Asian journal of surgery

2022 Volume 45, Issue 9, Page(s) 1712–1714

MeSH term(s)	Humans ; Kidney/injuries ; Lithotripsy/adverse effects
Language	English
Publishing date	2022-05-18
Publishing country	China
Document type	Letter
ZDB-ID	1068461-x
ISSN	0219-3108 ; 1015-9584
ISSN (online)	0219-3108
ISSN	1015-9584
DOI	10.1016/j.asjsur.2022.05.035
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Article ; Online: An integrated microfluidic chip for alginate microsphere generation and 3D cell culture.

Zhou, Xiaoxiang / Zhu, Libo / Li, Weihao / Liu, Quanjun

Analytical methods : advancing methods and applications

2022 Volume 14, Issue 12, Page(s) 1181–1186

Abstract: Three-dimensional (3D) hydrogel microspheres have attracted increasing attention as cell culture carriers. The system of hydrogel microspheres provides great advantages for cell growth owing to its high surface-to-volume ratio and biocompatible ... ...

Abstract	Three-dimensional (3D) hydrogel microspheres have attracted increasing attention as cell culture carriers. The system of hydrogel microspheres provides great advantages for cell growth owing to its high surface-to-volume ratio and biocompatible environment. However, an integrated system that includes microsphere generation, microsphere capture and
MeSH term(s)	Alginates ; Cell Culture Techniques, Three Dimensional ; Hydrogels ; Microfluidics/methods ; Microspheres
Chemical Substances	Alginates ; Hydrogels
Language	English
Publishing date	2022-03-24
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2515210-5
ISSN	1759-9679 ; 1759-9660
ISSN (online)	1759-9679
ISSN	1759-9660
DOI	10.1039/d1ay01820e
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Article ; Online: Phenotypic and genotypic analysis of a patient with Miyoshi myopathy caused by truncated protein.

Zhou, Jinyi / Zhou, Rui / Feng, Qihua / Song, Xiaoxiang / Chen, Xuqin

Gene

2023 Volume 893, Page(s) 147929

Abstract: Dysferlin protein deficiency can cause neuromuscular dysfunction, resulting in autosomal recessive dysferlinopathy, which is caused by DYSF gene mutation. Dysferlin proteins belongs to the Ferlin1-like protein family and are associated with muscle ... ...

Abstract	Dysferlin protein deficiency can cause neuromuscular dysfunction, resulting in autosomal recessive dysferlinopathy, which is caused by DYSF gene mutation. Dysferlin proteins belongs to the Ferlin1-like protein family and are associated with muscle membrane repair and regeneration. In China, pathogenic mutations of the protein often result in two clinical phenotypes of Miyoshi muscular or limb band muscular dystrophy type 2B. It is clinically characterized by progressive muscle weakness and elevated serum creatine kinase. The data of the child were collected, blood samples of the child and his family members were collected, and whole exome sequencing (WES) was performed. The recombinant expression vector was constructed, the function of the mutation was verified by minigene, and the pathogenicity of the mutation was further analyzed by combining with biological information analysis. The patient initially presented with asymptomatic elevation of serum creatine kinase（CK）. Then progressive lower limb weakness, mainly distal limb weakness. Large amounts of scattered necrosis, myogenic lesions, and complete deletion of dysferlin protein were observed under muscle biopsy, which further improved genetic detection. Whole exome sequencing showed compound mutations (c.1397 + 1_1397 + 3del and c.1375dup p.M459Nfs15) in DYSF gene. c.1375dup p.M459Nfs15 have been reported. The other mutation is the deletion of c.1397 + 1_1397 + 3 in Intron15, which is an intron mutation that may affect splicing and the pathogenesis is still unknown. Minigene splicing assay verified that c.1397 + 1_1397 + 3del resulted in exon15 skipping and produced a premature termination codon. We report a novel pathogenic mutation in DYSF gene with Miyoshi myopathy and demonstrate this variant causes skipping of exon15 by minigene splicing assay. We point out the need of conducting functional analysis to verify the pathogenicity of intronic mutation. The finding enriches the mutation spectrum of DYSF gene and laid a foundation for future studies on the correlation between genotype and phenotype.
MeSH term(s)	Child ; Humans ; Dysferlin/genetics ; Phenotype ; Genotype ; Creatine Kinase/genetics ; Muscular Atrophy ; Distal Myopathies
Chemical Substances	Dysferlin ; Creatine Kinase (EC 2.7.3.2)
Language	English
Publishing date	2023-10-29
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	391792-7
ISSN	1879-0038 ; 0378-1119
ISSN (online)	1879-0038
ISSN	0378-1119
DOI	10.1016/j.gene.2023.147929
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Zs.A 1357: Show issues

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Article ; Online: Clinical Outcomes of Arthroscopic Surgery in Patients with Gluteal Muscle Contracture: Single-Institution Results from a High-Volume Cohort.

Hu, Jianhai / Zhu, Jiazhuang / Zhou, Zheng / Yang, Xiaoxiang / Zhu, Min / Wu, Peng

Medical science monitor : international medical journal of experimental and clinical research

2024 Volume 30, Page(s) e942945

Abstract: BACKGROUND The aim of this study was to assess clinical outcomes of arthroscopic surgery for gluteal muscle contracture (GMC) with at least 2 years of follow-up in a large sample. MATERIAL AND METHODS A total of 665 patients who underwent arthroscopic ... ...

Abstract	BACKGROUND The aim of this study was to assess clinical outcomes of arthroscopic surgery for gluteal muscle contracture (GMC) with at least 2 years of follow-up in a large sample. MATERIAL AND METHODS A total of 665 patients who underwent arthroscopic release procedure at our institution between March 2014 and December 2018 and met the inclusion criteria were included in this study. All the patients were operated on by the same surgeon and the surgeon released the contracture band from anterior to posterior starting from the anterior edge of the ITB, the contracture band of the gluteus maximus, and vastus medialis tensor. After exclusion, 544 patients (218 males and 326 females) were finally included. Clinical outcomes at 2 years of postoperative follow-up were evaluated by a combination of several methods, including a new criterion we proposed for postoperative assessment, which included the cross-leg test, difficulty in squatting with legs together, and abnormal gait, the visual analogue scale (VAS), the modified Harris hip score (mHHS), and the satisfaction of patients. RESULTS The average follow-up time was 48.2±14.9 months. Based on the new criteria, 513 (94.3%) patients were evaluated as good, 25 (4.6%) as fair, and 6 (1.1%) as poor. The mHHS increased from 72.1±6.0 (range, 56.0-81.3) to 97.3±2.2 (range, 92.3-100.0) (P<0.001). The VAS decreased from 3.3±1.1 (range, 0-5) to 0.062±0.13 (range, 0-1) (P<0.001). For subjective satisfaction, 526 (96.7%) patients were satisfied, 14 (2.6%) patients were neutral, and 4 (0.7%) patients were dissatisfied. CONCLUSIONS In a large sample, favorable and durable clinical outcomes were observed after the arthroscopic procedure. Clinical symptoms and mHHS showed significant improvement with a minimum 2-year follow-up.
MeSH term(s)	Female ; Male ; Humans ; Arthroscopy ; Lower Extremity ; Contracture/surgery ; Leg ; Quadriceps Muscle
Language	English
Publishing date	2024-03-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	1439041-3
ISSN	1643-3750 ; 1234-1010
ISSN (online)	1643-3750
ISSN	1234-1010
DOI	10.12659/MSM.942945
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Zs.A 4924: Show issues

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Article ; Online: A lightweight segmentation network for endoscopic surgical instruments based on edge refinement and efficient self-attention

Mengyu Zhou / Xiaoxiang Han / Zhoujin Liu / Yitong Chen / Liping Sun

PeerJ Computer Science, Vol 9, p e

2023 Volume 1746

Abstract: In robot-assisted surgical systems, surgical instrument segmentation is a critical task that provides important information for surgeons to make informed decisions and ensure surgical safety. However, current mainstream models often lack precise ... ...

Abstract	In robot-assisted surgical systems, surgical instrument segmentation is a critical task that provides important information for surgeons to make informed decisions and ensure surgical safety. However, current mainstream models often lack precise segmentation edges and suffer from an excess of parameters, rendering their deployment challenging. To address these issues, this article proposes a lightweight semantic segmentation model based on edge refinement and efficient self-attention. The proposed model utilizes a lightweight densely connected network for feature extraction, which is able to extract high-quality semantic information with fewer parameters. The decoder combines a feature pyramid module with an efficient criss-cross self-attention module. This fusion integrates multi-scale data, strengthens focus on surgical instrument details, and enhances edge segmentation accuracy. To train and evaluate the proposed model, the authors developed a private dataset of endoscopic surgical instruments. It containing 1,406 images for training, 469 images for validation and 469 images for testing. The proposed model performs well on this dataset with only 466 K parameters, achieving a mean Intersection over Union (mIoU) of 97.11%. In addition, the model was trained on public datasets Kvasir-instrument and Endovis2017. Excellent results of 93.24% and 95.83% were achieved on the indicator mIoU, respectively. The superiority and effectiveness of the method are proved. Experimental results show that the proposed model has lower parameters and higher accuracy than other state-of-the-art models. The proposed model thus lays the foundation for further research in the field of surgical instrument segmentation.
Keywords	Surgical instruments ; Semantic segmentation ; Lightweight network ; Efficient self-attention ; Electronic computers. Computer science ; QA75.5-76.95
Subject code	006
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A lightweight segmentation network for endoscopic surgical instruments based on edge refinement and efficient self-attention.

Zhou, Mengyu / Han, Xiaoxiang / Liu, Zhoujin / Chen, Yitong / Sun, Liping

PeerJ. Computer science

2023 Volume 9, Page(s) e1746

Abstract	In robot-assisted surgical systems, surgical instrument segmentation is a critical task that provides important information for surgeons to make informed decisions and ensure surgical safety. However, current mainstream models often lack precise segmentation edges and suffer from an excess of parameters, rendering their deployment challenging. To address these issues, this article proposes a lightweight semantic segmentation model based on edge refinement and efficient self-attention. The proposed model utilizes a lightweight densely connected network for feature extraction, which is able to extract high-quality semantic information with fewer parameters. The decoder combines a feature pyramid module with an efficient criss-cross self-attention module. This fusion integrates multi-scale data, strengthens focus on surgical instrument details, and enhances edge segmentation accuracy. To train and evaluate the proposed model, the authors developed a private dataset of endoscopic surgical instruments. It containing 1,406 images for training, 469 images for validation and 469 images for testing. The proposed model performs well on this dataset with only 466 K parameters, achieving a mean Intersection over Union (mIoU) of 97.11%. In addition, the model was trained on public datasets Kvasir-instrument and Endovis2017. Excellent results of 93.24% and 95.83% were achieved on the indicator mIoU, respectively. The superiority and effectiveness of the method are proved. Experimental results show that the proposed model has lower parameters and higher accuracy than other state-of-the-art models. The proposed model thus lays the foundation for further research in the field of surgical instrument segmentation.
Language	English
Publishing date	2023-12-11
Publishing country	United States
Document type	Journal Article
ISSN	2376-5992
ISSN (online)	2376-5992
DOI	10.7717/peerj-cs.1746
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Article ; Online: Nanoparticle-Based MRI-Guided Tumor Microenvironment Heating via the Synergistic Effect of Ferroptosis and Inhibition of TGF-β Signaling.

Zhou, Rui / Liu, Yantan / Wang, Zhaojun / Lv, Jinyu / Liao, Wangjun / Shen, Zheyu / Rong, Xiaoxiang

Advanced healthcare materials

2023 Volume 12, Issue 21, Page(s) e2300176

Abstract: Although induction of ferroptosis and inhibition of transforming growth factor-β (TGF-β) signaling are both effective ways to reform the tumor microenvironment (TME) and render low-immunogenic tumors responsive to immune checkpoint inhibitor therapy, ... ...

Abstract	Although induction of ferroptosis and inhibition of transforming growth factor-β (TGF-β) signaling are both effective ways to reform the tumor microenvironment (TME) and render low-immunogenic tumors responsive to immune checkpoint inhibitor therapy, dose-limiting side effects remain major obstacles hindering their clinical application. Herein, novel sorafenib and anti-TGF-β antibody loaded Fe
MeSH term(s)	Humans ; Sorafenib/pharmacology ; Transforming Growth Factor beta/metabolism ; Ferroptosis ; Tumor Microenvironment ; CD8-Positive T-Lymphocytes ; Heating ; Neoplasms/drug therapy ; Nanoparticles ; Cell Line, Tumor
Chemical Substances	Sorafenib (9ZOQ3TZI87) ; Transforming Growth Factor beta
Language	English
Publishing date	2023-05-04
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2649576-4
ISSN	2192-2659 ; 2192-2640
ISSN (online)	2192-2659
ISSN	2192-2640
DOI	10.1002/adhm.202300176
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