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Book ; Online: Novel Wastewater Treatment Applications Using Polymeric Materials

Fahim, Irene S / Badawi, Ahmed K / Emam, Hossam E / Badawi, Ahmed K

2023

Keywords	Chemistry ; Technology: general issues ; cyanoguanidine-modified chitosan adsorbent ; Congo red dye ; adsorption kinetics ; adsorption isotherms ; adsorption thermodynamic ; Nelumbo nucifera leaf adsorbent ; fixed-bed column ; immobilization ; breakthrough curve ; desorption ; polymer complexant ; rare earth separation ; phosphorylated chitosan ; complexation-ultrafiltration ; kinetic study ; Eucalyptus ; biochar ; arsenic ; fluoride ; methylene blue ; activated carbon ; agro-waste ; wastewater ; adsorption ; cationic dyes ; low-cost adsorbents ; bio-waste ; Sargassum latifolium ; methylene blue dye ; water pollution ; equilibrium isotherm ; plasma ; produced water ; membranes ; desalination ; gliding arc ; nanofiltration ; nanofibers ; ROMP ; thiol-functionalized polymer ; polynorbornene dicarboximide ; heavy metal adsorption ; lead ; cadmium ; nickel ; fabrication techniques ; inorganic contaminants ; organic pollutants ; polymer nanocomposites ; water treatment ; polyamine ; industrial wastewater treatment ; heavy metal ions ; hypercrosslinked polymer ; porous polymer ; catechol ; Fenton catalyst ; dye degradation ; nanofilter ; nanocomposite ; water ; purification ; capillary-driven flow ; biocompatible ; biodegradable ; Ismate violet 2R dye ; IV2R ; ZnO-NP ; BET ; kinetics ; isotherm modelling ; thermodynamic ; poly(N-isopropylacrylamide) (PNIPAAm) ; thermo-responsive membrane ; hydrophilic hydrogel support ; interfacial polymerization ; electrospun nanofibers ; polyethylene terephthalate ; superhydrophobic nanosilica ; solid-phase microextraction ; organochlorine pesticides ; electrospun-nanofibers ; Calix[4]arene ; polyurethane ; polysulfone ; extraction ; chlorobenzenes ; heavy metals ; environmental remediation ; polyaniline ; coconut fiber ; electrospinning ; nickel titanate ; photodegradation ; mathematical modeling
Language	English
Size	1 electronic resource (354 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030379142
ISBN	9783036562445 ; 3036562443
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Idiopathic pulmonary fibrosis-A challenging disease with new horizons and changing therapeutic landscape.

Fahim, Ahmed

The clinical respiratory journal

2021 Volume 15, Issue 4, Page(s) 369–373

Abstract: Objectives: To discuss the pathophysiological hypotheses of IPF with a view to summarise the data on pharmacological aspects of treatment of this fibrotic Interstitial Lung Disease. Furthermore, the adverse effects are briefly discussed for the ... ...

Abstract	Objectives: To discuss the pathophysiological hypotheses of IPF with a view to summarise the data on pharmacological aspects of treatment of this fibrotic Interstitial Lung Disease. Furthermore, the adverse effects are briefly discussed for the currently available and licenced anti-fibrotic agents. Data source: The data were obtained from the Randomised Controlled Trials and scientific studies published in English literature. The manuscript is kept brief to provide an overview of pathophysiological and pharmacological interplay involved in IPF and it was aimed not to be exhaustive so an update is provided on the aspect of pharmacotherapeutics for physicians involved in managing patients with IPF. Results: Two pharmacological agents Pirfenidone and Nintedanib are discussed with the evidence backing up for the rationale of these drugs to slow the disease progression and potentially improve mortality in this disease with a dismal prognosis. The drugs are associated with adverse events and a careful consideration to balance the efficacy with quality of life of individual patient should be considered before commencing these medications. We are seeing real-world data on the value of these anti-fibrotic agents and there is further evidence of them to be efficacious in severe disease and even in the cohort with significant progression over 6-12 months period. Conclusion: The landscape of IPF management has seen a paradigm shift in the last decade form anti-inflammatory to anti-fibrotic approach and with evidence of slowing disease progression. We are likely to improve IPF management in the near future with multi-modality and personalised therapy.
MeSH term(s)	Anti-Inflammatory Agents/therapeutic use ; Humans ; Idiopathic Pulmonary Fibrosis/drug therapy ; Lung Diseases, Interstitial ; Quality of Life
Chemical Substances	Anti-Inflammatory Agents
Language	English
Publishing date	2021-01-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2442214-9
ISSN	1752-699X ; 1752-6981
ISSN (online)	1752-699X
ISSN	1752-6981
DOI	10.1111/crj.13322
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effects of CBD (Cannabidiol) on the physiology of Nile tilapia (Oreochromisn niloticus) as a chronic stress mitigating agent In-vivo.

Mortuza, Asif / Fahim, Nahian / Ahmed, Malaika / Mustafa, Ahmed

PloS one

2023 Volume 18, Issue 9, Page(s) e0290835

Abstract: This study evaluates the effects of Cannabidiol (CBD) on the physiology of stressed and non-stressed Nile tilapia, reared in a recirculating aquaculture system. Tilapia were fed with and without CBD (0.001% of feed weight) and with and without ... ...

Abstract	This study evaluates the effects of Cannabidiol (CBD) on the physiology of stressed and non-stressed Nile tilapia, reared in a recirculating aquaculture system. Tilapia were fed with and without CBD (0.001% of feed weight) and with and without hydrocortisone stress hormone (0.01% of body weight) every day for four weeks. This experiment compared the plasma cortisol, blood glucose and protein levels, liver and spleen somatic indices (HSI and SSI, respectively), and lysozyme activity of the fish. Stress group (S) had a significantly higher value than the control group (C) in two of the parameters, glucose and lysozyme activity, this is an indication of stress. CBD had a stress reducing effect under stressed conditions in lysozyme activity. Although not significant, the stress reducing effect of CBD on stress biomarkers such as glucose and HSI also seemed promising. Further investigation into the matter may not just be useful in stress mediation in aquatic organisms but may also have implications in human medicine as well.
MeSH term(s)	Animals ; Humans ; Cichlids ; Cannabidiol/pharmacology ; Muramidase ; Tilapia ; Glucose
Chemical Substances	Cannabidiol (19GBJ60SN5) ; Muramidase (EC 3.2.1.17) ; Glucose (IY9XDZ35W2)
Language	English
Publishing date	2023-09-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0290835
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Assessment of PD-1 and PD-L1 tissue expression levels in lichen planus patients: a case-control study.

Elmasry, Maha Fathy / Mosaad, Rana Ahmed / Azzam, Omar Ahmed / Rashed, Laila Ahmed / Fahim, Aya

Archives of dermatological research

2024 Volume 316, Issue 3, Page(s) 97

Abstract: Programmed cell death protein-1 (PD-1) is an immune checkpoint protein, PD-1 interaction with PD ligand-1 (PD-L1) is essential for maintaining immunological tolerance. The study aimed to study and compare the levels of PD-1 and PD-L1 in lesional and ... ...

Abstract	Programmed cell death protein-1 (PD-1) is an immune checkpoint protein, PD-1 interaction with PD ligand-1 (PD-L1) is essential for maintaining immunological tolerance. The study aimed to study and compare the levels of PD-1 and PD-L1 in lesional and nonlesional skin of lichen planus (LP) patients and compare these levels to normal healthy controls to assess their role in the pathogenesis of LP. This case-control study involved 30 patients with LP and 30 healthy age-and sex-matched controls. After clinical assessment of the severity by LP severity index score (LPSI), skin biopsies were taken from lesional and nonlesional skin of LP patients and from normal skin in healthy controls for assessment of the tissue levels of PD-1 and PD-L1 by ELISA. The tissue levels of both PD-1 and PD-L1 were significantly higher in healthy controls than in both lesional and nonlesional skin of LP patients (P < 0.001). Also, significantly higher PD-l and PD-L1 levels in nonlesional skin than in lesional skin of LP patients were reported (P < 0.001). No significant correlations were found between lesional and nonlesional PD-1, PD-L1 levels, or LPSI score. Based on the fact that PD-1/PD-L1 interaction is important to maintain tolerance and protection against autoimmune diseases, in addition to our study results that revealed lower levels of PD-1/PD-L1 in LP skin than in healthy skin, we can conclude that PD-1/PDL-1 may be incriminated in the pathogenesis of LP. ClinicalTrials.govID: NCT04892381.
MeSH term(s)	Humans ; B7-H1 Antigen/metabolism ; Case-Control Studies ; Lichen Planus/metabolism ; Ligands ; Programmed Cell Death 1 Receptor
Chemical Substances	B7-H1 Antigen ; Ligands ; Programmed Cell Death 1 Receptor
Language	English
Publishing date	2024-03-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	130131-7
ISSN	1432-069X ; 0340-3696
ISSN (online)	1432-069X
ISSN	0340-3696
DOI	10.1007/s00403-024-02838-z
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Article ; Online: Work-related musculoskeletal complaints and ergonomic risk factors among Egyptian anesthesiologists: a cross-sectional study.

Fouad, Ahmed Mahmoud / Fahim, Ayman Ekram / Bedewy, Ahmed Abdelmohsen / Al-Touny, Aiman / Al-Touny, Shimaa A

BMC public health

2024 Volume 24, Issue 1, Page(s) 279

Abstract: Background: Anesthesiologists are vulnerable to work-related musculoskeletal disorders (WMSDs) due to sustained repetitive movements and awkward postures. This study aimed to assess the prevalence of WMSDs among anesthesiologists and to evaluate its ... ...

Abstract	Background: Anesthesiologists are vulnerable to work-related musculoskeletal disorders (WMSDs) due to sustained repetitive movements and awkward postures. This study aimed to assess the prevalence of WMSDs among anesthesiologists and to evaluate its association with ergonomic risk factors. Methods: A convenience sample of 380 Egyptian anesthesiologists were invited to participate in this cross-sectional study through an electronic questionnaire. Data were collected from May to August 2022 and involved questions about participants' demographic, health, and work-related characteristics; the ergonomic risks and perceived hazards; and the musculoskeletal complaints during the past 12 months and 7 days - using Nordic Musculoskeletal Questionnaire (NMQ). Descriptive, bivariate, and multivariate statistical analyses were used to estimate the prevalence of MSD and identify its determinants in the studied sample. Results: A total of 215 anesthesiologists were included in this study, with a 56.8% response rate, 66% males with an average age of 38 (± 0.7) years. 21% were resident physicians, 47% were specialists, and 32% were consultants. The 12-month prevalence of MSD among anesthesiologists was 71.6% (95% CI: 65.6- 77.7%). Multivariate analysis showed that the main determinants of MSD among the studied sample were age of 45-years and older (OR: 3.22, 95% CI: 1.21-8.52, p = 0.018), regular physical exercise (OR: 0.25, 95% CI: 0.10-0.65, p = 0.005), insufficient rest time between procedures (OR: 2.25, 95% CI: 1.15-4.41, p = 0.018), and three or more awkward postures of the trunk (OR: 3.55, 95% CI: 1.43-8.82, p = 0.006). Conclusions: The study highlights a high prevalence of WMSDs among Egyptian anesthesiologists, linked to advancing age, lack of regular exercise, insufficient rest between procedures, and frequent awkward postures. Addressing these ergonomic risk factors through targeted workplace interventions is crucial for promoting the overall well-being of anesthesiologists and ensuring the provision of safe anesthesia services.
MeSH term(s)	Male ; Humans ; Adult ; Middle Aged ; Female ; Cross-Sectional Studies ; Anesthesiologists ; Egypt ; Ergonomics ; Risk Factors
Language	English
Publishing date	2024-01-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-024-17757-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The efficacy of 2780 nm Er,Cr;YSGG and 940 nm Diode Laser in root canal disinfection: A randomized clinical trial.

Fahim, Sara Zakaria / Ghali, Rami Maher / Hashem, Ahmed A / Farid, Mary Medhat

Clinical oral investigations

2024 Volume 28, Issue 3, Page(s) 175

Abstract: Objectives: Effective disinfection of the root canals is the cornerstone of successful endodontic treatment. Diminishing the microbial load within the root canal system is crucial for healing in endodontically treated teeth. The aim of this study was to ...

Abstract	Objectives: Effective disinfection of the root canals is the cornerstone of successful endodontic treatment. Diminishing the microbial load within the root canal system is crucial for healing in endodontically treated teeth. The aim of this study was to evaluate the effect of 2780 nm Er,Cr:YSGG and 940 nm diode lasers on the eradication of microorganisms from single-rooted teeth with asymptomatic apical periodontitis. Materials and methods: Thirty participants conforming to the inclusion criteria were randomly divided into 3 groups according to the disinfection protocol used; Conventional group: 2.5% Sodium Hypochlorite (NaOCl) and 17% EDTA solution NaOCl/EDTA, Dual laser group: 2780 nm Erbium, chromium: yttrium scandium-gallium-garnet (Er,Cr:YSGG) laser and 940 nm diode laser Er,CrYSGG/Diode, and Combined group: 17% EDTA and 940 nm diode laser EDTA/Diode. Bacterial samples were collected before and after intervention. The collected data were statistically analyzed using Friedman's test and Kruskal-Wallis test (P ≤ 0.05). Results: The results of the study showed that both dual laser Er,CrYSGG/Diode and combined laser EDTA/Diode groups showed significantly less mean Log10 CFU/ml of aerobic and anaerobic bacterial counts than the conventional NaOCl/EDTA group. Conclusions: In this study we evaluated in vivo the bactericidal efficacy of three disinfection protocols for endodontic treatment of single-rooted teeth with apical periodontitis. The results indicated that both dual laser Er,CrYSGG/Diode and combined laser EDTA/Diode groups provide superior bactericidal effect compared to the conventional NaOCl/EDTA group. Clinical relevance: The integration of lasers into root canal disinfection protocols has demonstrated significant bacterial reduction which might promote healing and long-term success.
MeSH term(s)	Humans ; Lasers, Semiconductor/therapeutic use ; Disinfection/methods ; Dental Pulp Cavity/microbiology ; Edetic Acid/pharmacology ; Edetic Acid/therapeutic use ; Enterococcus faecalis ; Root Canal Irrigants/pharmacology ; Sodium Hypochlorite/pharmacology ; Sodium Hypochlorite/therapeutic use ; Lasers, Solid-State/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Periapical Periodontitis/drug therapy
Chemical Substances	Edetic Acid (9G34HU7RV0) ; Root Canal Irrigants ; Sodium Hypochlorite (DY38VHM5OD) ; Anti-Bacterial Agents
Language	English
Publishing date	2024-02-26
Publishing country	Germany
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1364490-7
ISSN	1436-3771 ; 1432-6981
ISSN (online)	1436-3771
ISSN	1432-6981
DOI	10.1007/s00784-024-05563-z
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Article: F-quad helix for simultaneous maxillary expansion and tooth alignment in patients with unilateral cleft lip and/or palate.

Fahim, Fady Hussein / Othman, Ahmed / von See, Constantin

Clinical case reports

2023 Volume 11, Issue 6, Page(s) e7572

Abstract: Illustrating F-quad helix with extension arms that simultaneously expand maxillary arch and rotate its central incisor adjacent to the alveolar cleft while aligning palatally ectopic canines. Incisor rotation occurred before alveolar grafting, while ... ...

Abstract	Illustrating F-quad helix with extension arms that simultaneously expand maxillary arch and rotate its central incisor adjacent to the alveolar cleft while aligning palatally ectopic canines. Incisor rotation occurred before alveolar grafting, while canine traction was performed after alveolar grafting. The construction of this appliance is shown in detail.
Language	English
Publishing date	2023-06-17
Publishing country	England
Document type	Case Reports
ZDB-ID	2740234-4
ISSN	2050-0904
ISSN	2050-0904
DOI	10.1002/ccr3.7572
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Article ; Online: Chitosan nanoparticle encapsulation increased the prophylactic efficacy of Lactobacillus plantarum RM1 against AFM

Hassanen, Eman I / Ahmed, Lamiaa I / Fahim, Karima M / Shehata, Mohamed G / Badr, Ahmed N

Environmental science and pollution research international

2023 Volume 30, Issue 59, Page(s) 123925–123938

Abstract: Aflatoxin ... ...

Abstract	Aflatoxin M
MeSH term(s)	Rats ; Male ; Animals ; Lactobacillus plantarum ; Caspase 3 ; Chitosan/pharmacology ; Rats, Wistar ; Milk ; Inflammation ; Food Contamination
Chemical Substances	Caspase 3 (EC 3.4.22.-) ; Chitosan (9012-76-4)
Language	English
Publishing date	2023-11-23
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-31016-3
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Article: High Prevalence of Multidrug-Resistant Bacteria in the Trachea of Intensive Care Units Admitted Patients: Evidence from a Bangladeshi Hospital.

Haque, Sabrina / Ahmed, Akash / Islam, Nazrul / Haque, Fahim Kabir Monjurul

Antibiotics (Basel, Switzerland)

2024 Volume 13, Issue 1

Abstract: Recent research has shown that antibiotic-resistant microorganisms are becoming more prevalent in intensive care units (ICUs) at an exponential rate. Patients in the ICU can get infected by pathogens due to invasive operation procedures and critical ... ...

Abstract	Recent research has shown that antibiotic-resistant microorganisms are becoming more prevalent in intensive care units (ICUs) at an exponential rate. Patients in the ICU can get infected by pathogens due to invasive operation procedures and critical health conditions. This study primarily emphasized tracheal samples from ICU patients due to their reliance on ventilators, increasing their susceptibility to Ventilator-Associated Pneumonia (VAP). Moreover, the rise of multidrug-resistant (MDR) pathogens makes treatment strategies more challenging for these patients. In this study, we tested 200 tracheal specimens to determine the prevalence of microorganisms and analyzed the antibiotic susceptibility of these isolates against regular antibiotics, including 4th generation drugs. Among the 273 isolates, 81% were gram-negative bacteria, 10% were gram-positive bacteria, and 9% were fungi. The most prevalent gram-negative bacteria were
Language	English
Publishing date	2024-01-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2681345-2
ISSN	2079-6382
ISSN	2079-6382
DOI	10.3390/antibiotics13010062
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Article ; Online: Effects of L-Carnitine Supplementation on the Rate of Weight Gain and Biomarkers of Environmental Enteric Dysfunction in Children with Severe Acute Malnutrition: A Double-Blind Randomized Controlled Clinical Trial.

Alam, Jinat / Fahim, Shah Mohammad / Islam, Md Ridwan / Alam, Md Ashraful / Gazi, Md Amran / Ahmed, Tahmeed

The Journal of nutrition

2024 Volume 154, Issue 3, Page(s) 949–961

Abstract: Background: Severe acute malnutrition (SAM) is a major public health concern among low- and middle-income countries, where the majority of the children encountering this acute form of malnutrition suffer from environmental enteric dysfunction (EED). ... ...

Abstract	Background: Severe acute malnutrition (SAM) is a major public health concern among low- and middle-income countries, where the majority of the children encountering this acute form of malnutrition suffer from environmental enteric dysfunction (EED). However, evidence regarding the effects of L-carnitine supplementation on the rate of weight gain and EED biomarkers in malnourished children is limited. Objectives: We aimed to investigate the role of L-carnitine supplementation on the rate of weight gain, duration of hospital stays, and EED biomarkers among children with SAM. Methods: A prospective, double-blind, placebo-controlled, randomized clinical trial was conducted at the Nutritional Rehabilitation Unit (NRU) of Dhaka Hospital, International Centre for Diarrheal Disease Research, Bangladesh. Children with SAM aged 9-24 mo were randomly assigned to receive commercial L-carnitine syrup (100 mg/kg/d) or placebo for 15 d in addition to standard of care. A total of 98 children with Weight-for-Length-z-score (WLZ) < -3 Standard deviation were enrolled between October 2021 and March 2023. Analyses were conducted on an intention-to-treat basis. Results: The primary outcome variable, "rate of weight gain," was comparable between L-carnitine and placebo groups (2.09 ± 2.23 compared with 2.07 ± 2.70; P = 0.973), which was consistent even after adjusting for potential covariates (age, sex, Weight-for-Age z-score, asset index, and WASH practices) through linear regression [ß: 0.37; 95% confidence interval (CI): -0.63,1.37; P = 0.465]. The average hospital stay was ∼4 d. The results of adjusted median regression showed that following intervention, there was no significant difference in the EED biomarkers among the treatment arms; Myeloperoxidase (ng/mL) [ß: -1342.29; 95% CI: -2817.35, 132.77; P = 0.074], Neopterin (nmol/L) [ß: -153.33; 95% CI: -556.58, 249.91; P = 0.452], alpha-1-antitrypsin (mg/mL) [ß: 0.05; 95% CI: -0.15, 0.25; P = 0.627]. Initial L-carnitine (μmol/L) levels (median, interquartile range) for L-carnitine compared with placebo were 54.84 (36.0, 112.9) and 59.74 (45.7, 96.0), whereas levels after intervention were 102.05 (60.9, 182.1) and 105.02 (73.1, 203.7). Conclusions: Although our study findings suggest that L-carnitine bears no additional effect on SAM, we recommend clinical trials with a longer duration of supplementation, possibly with other combinations of interventions, to investigate further into this topic of interest. This trial was registered at clinicaltrials.gov as NCT05083637.
MeSH term(s)	Child ; Humans ; Infant ; Bangladesh ; Biomarkers ; Carnitine/therapeutic use ; Dietary Supplements ; Malnutrition ; Prospective Studies ; Severe Acute Malnutrition/drug therapy ; Weight Gain ; Double-Blind Method
Chemical Substances	Biomarkers ; Carnitine (S7UI8SM58A)
Language	English
Publishing date	2024-02-06
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	218373-0
ISSN	1541-6100 ; 0022-3166
ISSN (online)	1541-6100
ISSN	0022-3166
DOI	10.1016/j.tjnut.2024.01.031
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