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  1. Article: Esophageal Motility Disorders in Gastroesophageal Reflux Disease.

    Pandolfino, John E

    Gastroenterology & hepatology

    2024  Volume 19, Issue 10, Page(s) 600–602

    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2386402-3
    ISSN 1554-7914
    ISSN 1554-7914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Esophageal function testing

    Pandolfino, John E.

    (Gastrointestinal endoscopy clinics of North America ; 24,4)

    2014  

    Author's details ed. John E. Pandolfino
    Series title Gastrointestinal endoscopy clinics of North America ; 24,4
    Collection
    Language English
    Size XIV S., S. 528 - 692 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place New York, NY u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT018578699
    ISBN 978-0-323-32609-4 ; 0-323-32609-9
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Response to Herbella and Patti: Double checking of esophageal function tests.

    Carlson, Dustin A / Pandolfino, John E

    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

    2022  Volume 34, Issue 5, Page(s) e14325

    Language English
    Publishing date 2022-02-04
    Publishing country England
    Document type Letter
    ZDB-ID 1186328-6
    ISSN 1365-2982 ; 1350-1925
    ISSN (online) 1365-2982
    ISSN 1350-1925
    DOI 10.1111/nmo.14325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Updates in the Management of Erosive Esophagitis.

    Pandolfino, John E / Spechler, Stuart J / Yadlapati, Rena

    The Journal of family practice

    2023  Volume 72, Issue 8 Suppl, Page(s) S1–S12

    Abstract: Upon completion of this activity, participants will:Have increased knowledge regarding the Mechanistic differences between proton pump inhibitors (PPIs) and potassium-competitive acid blockers (PCABs) Evidence comparing PPIs with PCABs for the treatment ... ...

    Abstract Upon completion of this activity, participants will:Have increased knowledge regarding the Mechanistic differences between proton pump inhibitors (PPIs) and potassium-competitive acid blockers (PCABs) Evidence comparing PPIs with PCABs for the treatment of GERD and EE Have greater competence related to Selecting evidence-based treatments for EE.
    MeSH term(s) Humans ; Gastroesophageal Reflux/diagnosis ; Gastroesophageal Reflux/drug therapy ; Esophagitis ; Proton Pump Inhibitors/therapeutic use ; Peptic Ulcer
    Chemical Substances Proton Pump Inhibitors
    Language English
    Publishing date 2023-10-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197883-4
    ISSN 1533-7294 ; 0094-3509
    ISSN (online) 1533-7294
    ISSN 0094-3509
    DOI 10.12788/jfp.0666
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Response to Sanagapalli and Sweis.

    Carlson, Dustin A / Pandolfino, John E

    The American journal of gastroenterology

    2021  Volume 117, Issue 2, Page(s) 356–357

    Language English
    Publishing date 2021-04-15
    Publishing country United States
    Document type Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Letter ; Comment
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000001599
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Advances in the Diagnosis and Management of Achalasia and Achalasia-Like Syndromes: Insights From HRM and FLIP.

    Kahrilas, Peter J / Carlson, Dustin A / Pandolfino, John E

    Gastro hep advances

    2023  Volume 2, Issue 5, Page(s) 701–710

    Abstract: High-resolution manometry, Chicago Classification v4.0, the functional lumen imaging probe, Panometry, and peroral endoscopic myotomy (POEM) are all now integral parts of the landscape for managing achalasia or, more precisely, achalasia-like syndromes. ... ...

    Abstract High-resolution manometry, Chicago Classification v4.0, the functional lumen imaging probe, Panometry, and peroral endoscopic myotomy (POEM) are all now integral parts of the landscape for managing achalasia or, more precisely, achalasia-like syndromes. This narrative review examines the impact of these innovations on the management of achalasia-like syndromes. High-resolution manometry was the disruptive technology that prompted the paradigm shift to thinking of motility disorders as patterns of obstructive physiology involving the esophagogastric junction and/or the distal esophagus rather than as siloed entities. An early observation was that the cardinal feature of achalasia-impaired lower esophageal sphincter relaxation-can occur in several subtypes: without peristalsis, with pan-esophageal pressurization, with premature (spastic) distal esophageal contractions, or even with preserved peristalsis (esophagogastric junction outlet obstruction). Furthermore, there being no biomarker for achalasia, no manometric pattern is perfectly sensitive or specific for 'achalasia' and there is also no 'gold standard' for the diagnosis. Consequently, complimentary physiological testing with a timed barium esophagram or functional lumen imaging probe are employed both to improve the detection of patients likely to respond to treatments for 'achalasia' and to characterize other syndromes also likely to benefit from achalasia therapies. These findings have become particularly relevant with the development of a minimally invasive technique for performing a tailored esophageal myotomy, POEM. Now and in the future, optimal achalasia management is to render treatment in a phenotype-specific manner, that is, POEM calibrated in a patient-specific manner for obstructive physiology including the distal esophagus and more conservative strategies such as a short POEM or pneumatic dilation for obstructive physiology limited to the lower esophageal sphincter.
    Language English
    Publishing date 2023-02-09
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2772-5723
    ISSN (online) 2772-5723
    DOI 10.1016/j.gastha.2023.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: High-resolution manometry from the surgical point of view: Response to letter to the editor.

    Yadlapati, Rena / Pandolfino, John E

    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

    2021  Volume 33, Issue 6, Page(s) e14142

    MeSH term(s) Humans ; Manometry
    Language English
    Publishing date 2021-03-26
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1186328-6
    ISSN 1365-2982 ; 1350-1925
    ISSN (online) 1365-2982
    ISSN 1350-1925
    DOI 10.1111/nmo.14142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Practical manual of gastroesophageal reflux disease

    Vela, Marcelo F. / Richter, Joel E. / Pandolfino, John E.

    2013  

    Title variant Gastroesophageal reflux disease ; Gastroesophafeal reflux disease
    Author's details ed. by Marcelo F. Vela ; Joel E. Richter ; John E. Pandolfino
    Language English
    Size X, 342 S., [4] Bl. : Ill., graph. Darst.
    Publisher Wiley-Blackwell
    Publishing place Chichester
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT017565767
    ISBN 978-0-470-65626-6 ; 9781118444788 ; 9781118444795 ; 9781118444825 ; 0-470-65626-3 ; 1118444787 ; 1118444795 ; 1118444825
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: A Computer-Aided Detection (CADe) System Significantly Improves Polyp Detection in Routine Practice.

    Keswani, Rajesh N / Thakkar, Urvi / Sals, Alexandra / Pandolfino, John E

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2023  Volume 22, Issue 4, Page(s) 893–895.e1

    MeSH term(s) Humans ; Juniperus ; Colonic Polyps/diagnosis ; Diagnosis, Computer-Assisted ; Computers ; Colonoscopy
    Language English
    Publishing date 2023-09-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2023.09.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Secondary peristalsis and esophagogastric junction distensibility in symptomatic post-fundoplication patients.

    Lu, Michelle M / Kahrilas, Peter J / Teitelbaum, Ezra N / Pandolfino, John E / Carlson, Dustin A

    Neurogastroenterology and motility

    2024  Volume 36, Issue 4, Page(s) e14746

    Abstract: ... absent CR, and 2 (2%) spastic reactive CR. Compared with normal and borderline CRs (i.e., CR patterns ...

    Abstract Background: The impact of esophageal dysmotility among patients with post-fundoplication esophageal symptoms is not fully understood. This study aimed to investigate secondary peristalsis and esophagogastric junction (EGJ) opening biomechanics using functional lumen imaging probe (FLIP) panometry in symptomatic post-fundoplication patients.
    Methods: Eighty-seven adult patients post-fundoplication who completed FLIP for symptomatic esophageal evaluation were included. Secondary peristaltic contractile response (CR) patterns and EGJ opening metrics (EGJ distensibility index (EGJ-DI) and maximum EGJ diameter) were evaluated on FLIP panometry and analyzed against high-resolution manometry (HRM), patient-reported outcomes, and fundoplication condition seen on esophagram and/or endoscopy.
    Key results: FLIP CR patterns included 14 (16%) normal CR, 30 (34%) borderline CR, 28 (32%) impaired/disordered CR, 13 (15%) absent CR, and 2 (2%) spastic reactive CR. Compared with normal and borderline CRs (i.e., CR patterns with distinct, antegrade peristalsis), patients with impaired/disordered and absent CRs demonstrated significantly greater time since fundoplication (2.4 (0.6-6.8) vs. 8.9 (2.6-14.5) years; p = 0.002), greater esophageal body width on esophagram (n = 50; 2.3 (2.0-2.8) vs. 2.9 (2.4-3.6) cm; p = 0.013), and lower EGJ-DI (4.3 (2.7-5.4) vs. 2.6 (1.7-3.7) mm
    Conclusions & inferences: Symptomatic post-fundoplication patients were characterized by frequent abnormal secondary peristalsis after fundoplication, potentially worsening with time after fundoplication or related to EGJ outflow resistance.
    MeSH term(s) Adult ; Humans ; Fundoplication/adverse effects ; Esophageal Achalasia/diagnosis ; Peristalsis ; Esophagogastric Junction ; Manometry/methods ; Endoscopy, Gastrointestinal
    Language English
    Publishing date 2024-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1186328-6
    ISSN 1365-2982 ; 1350-1925
    ISSN (online) 1365-2982
    ISSN 1350-1925
    DOI 10.1111/nmo.14746
    Database MEDical Literature Analysis and Retrieval System OnLINE

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