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  1. Article ; Online: Editorial: adjuvanted recombinant zoster vaccine in adults with inflammatory bowel disease-time for universal recommendation?

    Macaluso, Fabio Salvatore / Orlando, Ambrogio

    Alimentary pharmacology & therapeutics

    2023  Volume 57, Issue 11, Page(s) 1343–1344

    MeSH term(s) Adult ; Humans ; Herpes Zoster Vaccine
    Chemical Substances Herpes Zoster Vaccine
    Language English
    Publishing date 2023-05-10
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/apt.17490
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    Zs.A 2206: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Author's reply: "Tofacitinib in ulcerative colitis-Small molecule but large effect".

    Macaluso, Fabio Salvatore / Orlando, Ambrogio

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2023  Volume 56, Issue 2, Page(s) 373–374

    MeSH term(s) Humans ; Colitis, Ulcerative/drug therapy ; Pyrimidines/therapeutic use ; Piperidines ; Treatment Outcome ; Pyrroles
    Chemical Substances tofacitinib (87LA6FU830) ; Pyrimidines ; Piperidines ; Pyrroles
    Language English
    Publishing date 2023-11-25
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2023.11.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1134: Show issues Location:
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  3. Article ; Online: Ozanimod for Ulcerative Colitis.

    Macaluso, Fabio S / Orlando, Ambrogio

    The New England journal of medicine

    2022  Volume 386, Issue 2, Page(s) 194

    MeSH term(s) Colitis, Ulcerative/drug therapy ; Humans ; Indans ; Oxadiazoles
    Chemical Substances Indans ; Oxadiazoles ; ozanimod (Z80293URPV)
    Language English
    Publishing date 2022-01-12
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2117224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.34: Show issues Location:
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  4. Article ; Online: Epidemiological trends in pediatric inflammatory bowel disease: The precious contribution of the registries promoted by scientific societies.

    Orlando, Ambrogio / Macaluso, Fabio Salvatore

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2022  Volume 54, Issue 4, Page(s) 415–416

    MeSH term(s) Child ; Colitis, Ulcerative ; Gastroenterology ; Humans ; Inflammatory Bowel Diseases/epidemiology ; Registries ; Societies, Scientific
    Language English
    Publishing date 2022-02-05
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2022.01.129
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    Zs.A 1134: Show issues Location:
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  5. Article ; Online: Effectiveness and Safety of Vedolizumab in Inflammatory Bowel Disease: A Comprehensive Meta-analysis of Observational Studies.

    Macaluso, Fabio Salvatore / Ventimiglia, Marco / Orlando, Ambrogio

    Journal of Crohn's & colitis

    2023  Volume 17, Issue 8, Page(s) 1217–1227

    Abstract: Background and aims: Many observational studies on the use of vedolizumab [VDZ] in patients with Crohn's disease [CD] and ulcerative colitis [UC] have been published in the past few years. We aimed to comprehensively summarise its effectiveness and ... ...

    Abstract Background and aims: Many observational studies on the use of vedolizumab [VDZ] in patients with Crohn's disease [CD] and ulcerative colitis [UC] have been published in the past few years. We aimed to comprehensively summarise its effectiveness and safety by pooling data only from observational studies.
    Methods: PubMed/Medline and Embase were systematically searched for observational studies on patients with CD and UC treated with VDZ through December 2021. The rates of clinical remission and overall adverse events were the primary outcomes. The rates of steroid-free clinical remission, clinical response, mucosal healing, C-reactive protein normalisation, loss of response, VDZ dose escalation, colectomy, serious adverse events, infections, and malignancies were considered as secondary outcomes.
    Results: In all, 88 studies comprising 25 678 patients [13 663 with CD and 12 015 with UC] met the inclusion criteria. In patients with CD, the pooled estimate rates of clinical remission were 36% at induction and 39% at maintenance. In patients with UC, the pooled estimate rates of clinical remission were 40% at induction and 45% at maintenance. The pooled estimate of incidence rate of adverse events was 34.6 per 100 person-years. At multivariable meta-regression analysis, studies with increased male proportion were independently associated with higher rates of clinical remission and steroid-free clinical remission at both induction and maintenance, and clinical response at maintenance in patients with CD. Studies with increased disease duration were independently associated with higher mucosal healing rates at maintenance in patients with UC.
    Conclusions: Observational studies demonstrated extensively the effectiveness of VDZ, with a reassuring safety profile.
    MeSH term(s) Humans ; Male ; Colitis, Ulcerative/drug therapy ; Colitis, Ulcerative/chemically induced ; Crohn Disease/drug therapy ; Gastrointestinal Agents/adverse effects ; Inflammatory Bowel Diseases/drug therapy ; Remission Induction ; Treatment Outcome ; Female ; Observational Studies as Topic
    Chemical Substances Gastrointestinal Agents ; vedolizumab (9RV78Q2002)
    Language English
    Publishing date 2023-07-17
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2390120-2
    ISSN 1876-4479 ; 1873-9946
    ISSN (online) 1876-4479
    ISSN 1873-9946
    DOI 10.1093/ecco-jcc/jjad043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6634: Show issues Location:
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  6. Article ; Online: Letter: propensity score-handle with care.

    Macaluso, Fabio Salvatore / Orlando, Ambrogio

    Alimentary pharmacology & therapeutics

    2020  Volume 53, Issue 2, Page(s) 360–361

    MeSH term(s) Antibodies, Monoclonal, Humanized ; Crohn Disease ; Humans ; Propensity Score ; Tumor Necrosis Factor-alpha ; Ustekinumab
    Chemical Substances Antibodies, Monoclonal, Humanized ; Tumor Necrosis Factor-alpha ; vedolizumab (9RV78Q2002) ; Ustekinumab (FU77B4U5Z0)
    Language English
    Publishing date 2020-12-27
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/apt.16179
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    Zs.A 2206: Show issues Location:
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  7. Article ; Online: Switching from SB2 to PF-06438179/GP1111 and back in inflammatory bowel disease: "The Superswitchers".

    Macaluso, Fabio Salvatore / Casà, Angelo / Renna, Sara / Grova, Mauro / Mannino, Mariella / Orlando, Ambrogio

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2023  Volume 55, Issue 3, Page(s) 424–425

    MeSH term(s) Humans ; Infliximab ; Biosimilar Pharmaceuticals ; Inflammatory Bowel Diseases
    Chemical Substances GP1111 ; Infliximab (B72HH48FLU) ; Biosimilar Pharmaceuticals
    Language English
    Publishing date 2023-01-04
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2022.12.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1134: Show issues Location:
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  8. Article ; Online: Author's Reply: ``Use of biologics for the management of Crohn's disease''.

    Bonovas, Stefanos / Macaluso, Fabio Salvatore / Piovani, Daniele / Papi, Claudio / Orlando, Ambrogio / Armuzzi, Alessandro

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2023  Volume 55, Issue 7, Page(s) 990

    MeSH term(s) Humans ; Biological Products/therapeutic use ; Crohn Disease/drug therapy
    Chemical Substances Biological Products
    Language English
    Publishing date 2023-06-01
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2023.04.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1134: Show issues Location:
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  9. Article ; Online: Could Patients With Inflammatory Bowel Disease Treated With Immunomodulators or Biologics Be at Lower Risk for Severe Forms of COVID-19?

    Macaluso, Fabio Salvatore / Orlando, Ambrogio

    Gastroenterology

    2020  Volume 160, Issue 5, Page(s) 1877–1878

    MeSH term(s) Biological Products/adverse effects ; COVID-19 ; Humans ; Immunologic Factors/adverse effects ; Inflammatory Bowel Diseases/drug therapy ; Inflammatory Bowel Diseases/epidemiology ; Pandemics ; Prognosis ; SARS-CoV-2 ; Spain
    Chemical Substances Biological Products ; Immunologic Factors
    Keywords covid19
    Language English
    Publishing date 2020-05-12
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2020.05.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Upper gastrointestinal tract involvement in Crohn's disease: A relevant yet underestimated problem.

    Maida, Marcello / Macaluso, Fabio Salvatore / Orlando, Ambrogio

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2021  Volume 53, Issue 12, Page(s) 1546–1547

    MeSH term(s) Crohn Disease/complications ; Humans ; Upper Gastrointestinal Tract/diagnostic imaging
    Language English
    Publishing date 2021-09-27
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2021.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1134: Show issues Location:
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