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  1. Article ; Online: The forced renaissance of telemedicine during COVID-19: A fellow-in-training's perspective.

    Waqar, Omar / Agarwal, Shradha

    The journal of allergy and clinical immunology. In practice

    2021  Volume 9, Issue 2, Page(s) 1039

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Telemedicine
    Language English
    Publishing date 2021-02-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2020.11.057
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  2. Article ; Online: A retrospective study on smell dysfunction in COVID-19 patients presenting to a tertiary care teaching hospital in Northern India

    Aditya Singhal / Akshay Jain / Shradha Agarwal

    Acta Medica International, Vol 10, Iss 2, Pp 117-

    2023  Volume 120

    Abstract: Introduction: The smell dysfunction in COVID-19 patients has remained an unexplained topic. The blood parameters' variability in COVID-19 patients with anosmia has been studied in few literatures. The study is aimed to find the association of anosmia ... ...

    Abstract Introduction: The smell dysfunction in COVID-19 patients has remained an unexplained topic. The blood parameters' variability in COVID-19 patients with anosmia has been studied in few literatures. The study is aimed to find the association of anosmia with the blood grouping and C-reactive protein (CRP) levels in coronavirus-infected patients. Materials and Methods: Database from Medical Records Department of a Tertiary Care Teaching Hospital in Northern India was searched from July 2020 to December 2020. Every fifth file was selected using the stratified random sampling. Laboratory-confirmed COVID-19 cases by reverse transcription-polymerase chain reaction files were included. Blood grouping and CRP levels were assessed and statistically correlated. Results: A total of 103 patients of coronavirus-associated infection with anosmia were included among which 52 (50.48%) patients were from moderate category of AIIMS-ICMR joint task Force's clinical guidelines. A total of 44 (42.71%) patients had moderate levels of elevated CRP. The blood Group B-type was found most commonly in 35 (33.98%) patients. The correlation of severity of COVID-19 infection with CRP was found to be statistically significant (Chi-square test statistic was 31.203 and P = 0.00023) in patients presenting with smell dysfunction. Conclusion: Anosmia was found to a suggestive symptom for the early identification of coronavirus-infected cases. In this study, CRP levels showed statistically significant association with anosmia in COVID-19 patients. Predilection for specific blood groups serves as platform for further research.
    Keywords abo grouping ; covid-19 ; c-reactive protein levels ; olfactory dysfunction ; Medicine ; R
    Subject code 616 ; 610
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Patient perspectives on penicillin allergy and testing.

    Harada, Kaoru / Baker, Mary Grace / Agarwal, Shradha

    Allergy and asthma proceedings

    2022  Volume 43, Issue 1, Page(s) 64–69

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Anti-Bacterial Agents/adverse effects ; Delivery of Health Care ; Drug Hypersensitivity/diagnosis ; Drug-Related Side Effects and Adverse Reactions ; Electronic Health Records ; Humans ; Penicillins/adverse effects
    Chemical Substances Anti-Bacterial Agents ; Penicillins
    Language English
    Publishing date 2022-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1312445-6
    ISSN 1539-6304 ; 1088-5412
    ISSN (online) 1539-6304
    ISSN 1088-5412
    DOI 10.2500/aap.2022.43.210090
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    Zs.A 1804: Show issues Location:
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  4. Article ; Online: Immediate adverse reactions to horse antithymocyte globulin: A 10-year single-center experience.

    Oh, Jessica / Agarwal, Shradha / Miller, Rachel L / Ho, Hsi-En

    The journal of allergy and clinical immunology. In practice

    2022  Volume 10, Issue 8, Page(s) 2176–2177.e1

    MeSH term(s) Anemia, Aplastic ; Animals ; Antilymphocyte Serum/adverse effects ; Horses ; Humans ; Immunosuppressive Agents/adverse effects
    Chemical Substances Antilymphocyte Serum ; Immunosuppressive Agents
    Language English
    Publishing date 2022-05-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2022.04.032
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  5. Article ; Online: Socioeconomic Status and Diet Quality in Children with and without Food Allergy.

    Vo, Thanh Viet Anh / Irizar, Haritz / Gibson, Kyle / Stanley, Stephanie / Agarwal, Shradha / Groetch, Marion / Do, Anh / Bunyavanich, Supinda

    The Journal of pediatrics

    2023  Volume 260, Page(s) 113337

    MeSH term(s) Child ; Humans ; Diet ; Food Hypersensitivity ; Social Class
    Language English
    Publishing date 2023-01-31
    Publishing country United States
    Document type Case Reports ; Research Support, N.I.H., Extramural
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2022.12.039
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  6. Article ; Online: Comparison of dietary intake between milk-allergic and non-food-allergic children.

    Gibson, Kyle / Stanley, Stephanie / Agarwal, Shradha / Groetch, Marion / Bunyavanich, Supinda

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2021  Volume 32, Issue 8, Page(s) 1872–1876

    MeSH term(s) Allergens ; Animals ; Child ; Diet ; Eating ; Humans ; Hypersensitivity ; Milk
    Chemical Substances Allergens
    Language English
    Publishing date 2021-07-16
    Publishing country England
    Document type Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.13581
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    Zs.A 3096: Show issues Location:
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  7. Article ; Online: Convalescent plasma therapy in COVID-19 and discharge status

    Neeraj Agarwal / Shradha Mishra / Arshad Ayub

    Journal of Family Medicine and Primary Care, Vol 10, Iss 10, Pp 3876-

    A systematic review

    2021  Volume 3881

    Abstract: Objective: Covid19 has emerged as a greatest threat of the decade worldwide. At present there is no certain treatment for treating coronavirus diseases, while some antiviral drugs (Remdesivir , Lopinavir and Ritonavir) are under investigation. Many ... ...

    Abstract Objective: Covid19 has emerged as a greatest threat of the decade worldwide. At present there is no certain treatment for treating coronavirus diseases, while some antiviral drugs (Remdesivir , Lopinavir and Ritonavir) are under investigation. Many countries including India have adopted the convalescent plasma therapy in the treatment of moderate to severely ill patients. Despite the treatment being given ,there are no such evidences on the utility and efficacy of convalescent plasma.Hence this study tries to find out the impact on the discharge status from hospital of the patients receiving the very therapy. Design: Systematic review and meta analysis. Setting: An extensive search was made, following PRISMA guidelines on online databases such as Pubmed, Google scholar and Science direct.Studies those fulfilled the inclusion and exclusion criteria ,were included and reviewed and analyzed for a common outcome(discharge status). Participants: A total of 6 eligible studies were analyzed qualitatively and quantitatively which included three case control, two case series and one case report. Results: The overall pooled discharge rate from the above studies was 75.7% after the CP therapy. When analyzed for relative risk , it showed CP therapy having a lower risk of staying in hospital (not getting discharged) when compared to Standard therapy ,overall RR (relative risk) being 0.946. Conclusion: Our study shows that there is always a higher rate of discharge and low risk of prolonged hospital stay in those patients who receive plasma therapy. CP therapy being a low cost and easy to administer therapy with very less adverse events, requires more focus on further research as it has a potential to become an ideal effective treatment option for COVID-19.
    Keywords convalescent plasma ; covid-19 ; discharge status ; plasma therapy ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Convalescent plasma therapy in COVID-19 and discharge status: A systematic review.

    Agarwal, Neeraj / Mishra, Shradha / Ayub, Arshad

    Journal of family medicine and primary care

    2021  Volume 10, Issue 10, Page(s) 3876–3881

    Abstract: Objective: Covid19 has emerged as a greatest threat of the decade worldwide. At present there is no certain treatment for treating coronavirus diseases, while some antiviral drugs (Remdesivir , Lopinavir and Ritonavir) are under investigation. Many ... ...

    Abstract Objective: Covid19 has emerged as a greatest threat of the decade worldwide. At present there is no certain treatment for treating coronavirus diseases, while some antiviral drugs (Remdesivir , Lopinavir and Ritonavir) are under investigation. Many countries including India have adopted the convalescent plasma therapy in the treatment of moderate to severely ill patients. Despite the treatment being given ,there are no such evidences on the utility and efficacy of convalescent plasma. Hence this study tries to find out the impact on the discharge status from hospital of the patients receiving the very therapy.
    Design: Systematic review and meta analysis.
    Setting: An extensive search was made, following PRISMA guidelines on online databases such as Pubmed, Google scholar and Science direct. Studies those fulfilled the inclusion and exclusion criteria ,were included and reviewed and analyzed for a common outcome(discharge status).
    Participants: A total of 6 eligible studies were analyzed qualitatively and quantitatively which included three case control, two case series and one case report.
    Results: The overall pooled discharge rate from the above studies was 75.7% after the CP therapy. When analyzed for relative risk , it showed CP therapy having a lower risk of staying in hospital (not getting discharged) when compared to Standard therapy ,overall RR (relative risk) being 0.946.
    Conclusion: Our study shows that there is always a higher rate of discharge and low risk of prolonged hospital stay in those patients who receive plasma therapy. CP therapy being a low cost and easy to administer therapy with very less adverse events, requires more focus on further research as it has a potential to become an ideal effective treatment option for COVID-19.
    Language English
    Publishing date 2021-11-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_2429_20
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  9. Article ; Online: Autoimmunity in common variable immunodeficiency.

    Agarwal, Shradha / Cunningham-Rundles, Charlotte

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2019  Volume 123, Issue 5, Page(s) 454–460

    Abstract: Objective: Common variable immunodeficiency (CVID) is a primary immunodeficiency that is clinically heterogeneous, characterized by both infectious and noninfectious complications. Although the hallmark of disease presentation is commonly a history of ... ...

    Abstract Objective: Common variable immunodeficiency (CVID) is a primary immunodeficiency that is clinically heterogeneous, characterized by both infectious and noninfectious complications. Although the hallmark of disease presentation is commonly a history of recurrent sinopulmonary infections, autoimmunity and noninfectious inflammatory conditions are increasingly associated with CVID.
    Data sources: A comprehensive literature search using PubMed of basic science and clinical articles was performed.
    Study selections: Articles discussing the association of autoimmunity with primary immunodeficiency, specifically CVID, were selected.
    Results: The most common autoimmune conditions are cytopenias, including immune thrombocytopenia purpura and hemolytic anemia, but organ-specific autoimmune/inflammatory complications involving the gastrointestinal, skin, joints, connective tissue, and respiratory tract. In most cases, immunoglobulin replacement therapy does not ameliorate or treat these inflammatory complications, and additional immunomodulatory treatments are needed.
    Conclusion: Mechanisms producing these conditions are poorly understood but include cytokine and cellular inflammatory pathways, and loss of tolerance to self-antigens through the multiple signaling molecules and pathways common to tolerance and immune deficiency.
    MeSH term(s) Autoimmune Diseases/immunology ; Autoimmunity ; Common Variable Immunodeficiency/immunology ; Gastrointestinal Diseases/immunology ; Hematologic Diseases/immunology ; Humans ; Lung Diseases/immunology ; Rheumatic Diseases/immunology ; Skin Diseases/immunology
    Language English
    Publishing date 2019-07-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2019.07.014
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    Uh III Zs.136: Show issues Location:
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  10. Book ; Online: CoralStyleCLIP

    Revanur, Ambareesh / Basu, Debraj / Agrawal, Shradha / Agarwal, Dhwanit / Pai, Deepak

    Co-optimized Region and Layer Selection for Image Editing

    2023  

    Abstract: Edit fidelity is a significant issue in open-world controllable generative image editing. Recently, CLIP-based approaches have traded off simplicity to alleviate these problems by introducing spatial attention in a handpicked layer of a StyleGAN. In this ...

    Abstract Edit fidelity is a significant issue in open-world controllable generative image editing. Recently, CLIP-based approaches have traded off simplicity to alleviate these problems by introducing spatial attention in a handpicked layer of a StyleGAN. In this paper, we propose CoralStyleCLIP, which incorporates a multi-layer attention-guided blending strategy in the feature space of StyleGAN2 for obtaining high-fidelity edits. We propose multiple forms of our co-optimized region and layer selection strategy to demonstrate the variation of time complexity with the quality of edits over different architectural intricacies while preserving simplicity. We conduct extensive experimental analysis and benchmark our method against state-of-the-art CLIP-based methods. Our findings suggest that CoralStyleCLIP results in high-quality edits while preserving the ease of use.

    Comment: CVPR 2023
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Subject code 006 ; 004
    Publishing date 2023-03-08
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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