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  1. Article ; Online: The continuous surprises that SARS-CoV-2 presents to the scientific community - Correspondence about the Paper Fusco G, Cardillo L, Levante M, Brandi S, Picazio G, Napoletano M, Martucciello A, Fiorito F, De Carlo E, De Martinis C. First serological evidence of SARS-CoV-2 natural infection in small ruminants: brief report. Vet Res Commun. 2023 sep;47(3):1741-1748. Doi: 10.1007/s11259-022-10044-3.

    Teixeira, Ana Izabel Passarella

    Veterinary research communications

    2024  Volume 48, Issue 2, Page(s) 1311–1312

    MeSH term(s) Animals ; COVID-19/veterinary ; SARS-CoV-2 ; Ruminants ; Antibodies, Viral
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2024-01-31
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 406735-6
    ISSN 1573-7446 ; 0165-7380
    ISSN (online) 1573-7446
    ISSN 0165-7380
    DOI 10.1007/s11259-024-10315-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mansoins C-F, Oligomeric Flavonoid Glucosides Isolated from Mansoa hirsuta Fruits with Potential Anti-inflammatory Activity.

    Campana, Priscilla R V / Coleman, Christina M / Sousa, Lirlândia P / Teixeira, Mauro M / Ferreira, Daneel / Braga, Fernão C

    Journal of natural products

    2016  Volume 79, Issue 9, Page(s) 2279–2286

    Abstract: ... to 1,3-diarylpropane C6-C3-C6 units. The structures and absolute configurations of mansoins C-F (3-6 ... were established by analysis of NMR and electronic circular dichroism data. Mansoin C (3) was ... identified as a diglucosylated heterodimer, whereas mansoins D (4), E (5), and F (6) were identified ...

    Abstract Continued investigation of the polyphenolic pool of the fruits of Mansoa hirsuta afforded four additional members of the new class of glucosylated oligomeric flavonoids comprising a flavanone core linked to 1,3-diarylpropane C6-C3-C6 units. The structures and absolute configurations of mansoins C-F (3-6) were established by analysis of NMR and electronic circular dichroism data. Mansoin C (3) was identified as a diglucosylated heterodimer, whereas mansoins D (4), E (5), and F (6) were identified as triglucosylated heterotrimers, isomeric with mansoin A (1). Mansoin F (6) inhibited TNF-α release by lipopolysaccharide-stimulated THP-1 cells (IC50 of 19.3 ± 1.3 μM) and, as with mansoin A (1), reduced the phosphorylation levels of p-65-NF-κB, when assayed at 50 μM. These results indicate that the potential anti-inflammatory properties of mansoin F (6) are probably due to inhibition of the NF-κB pathway and inhibition of TNF-α release.
    MeSH term(s) Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/pharmacology ; Bignoniaceae/chemistry ; Flavonoids/chemistry ; Flavonoids/isolation & purification ; Flavonoids/pharmacology ; Fruit/chemistry ; Glucosides/chemistry ; Glucosides/isolation & purification ; Glucosides/pharmacology ; Humans ; Lipopolysaccharides/pharmacology ; Molecular Structure ; NF-kappa B/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
    Chemical Substances Anti-Inflammatory Agents ; Flavonoids ; Glucosides ; Lipopolysaccharides ; NF-kappa B ; Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2016-09-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/acs.jnatprod.6b00390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Embryo development in association with asymbiotic seed germination in vitro of Paphiopedilum armeniacum S. C. Chen et F. Y. Liu.

    Zhang, Yan-Yan / Wu, Kun-Lin / Zhang, Jian-Xia / Deng, Ru-Fang / Duan, Jun / Teixeira da Silva, Jaime A / Huang, Wei-Chang / Zeng, Song-Jun

    Scientific reports

    2015  Volume 5, Page(s) 16356

    Abstract: This paper documents the key anatomical features during the development of P. armeniacum zygotic embryos and their ability to germinate asymbiotically in vitro. This study also examines the effect of media and seed pretreatments on seed germination and ... ...

    Abstract This paper documents the key anatomical features during the development of P. armeniacum zygotic embryos and their ability to germinate asymbiotically in vitro. This study also examines the effect of media and seed pretreatments on seed germination and subsequent seedling growth. Seeds collected from pods 45 days after pollination (DAP) did not germinate while 95 DAP seeds displayed the highest seed germination percentage (96.2%). Most seedlings (50%) developed to stage 5 from 110 DAP seeds whose compact testa had not yet fully formed. Suspensor cells were vacuolated, which enabled the functional uptake of nutrients. The optimum basal medium for seed germination and subsequent protocorm development was eighth-strength Murashige and Skoog (1/8MS) for 95 DAP seeds and ¼MS for 110 DAP seeds. Poor germination was displayed by 140 DAP seeds with a compact testa. Pretreatment of dry mature seeds (180 DAP) with 1.0% sodium hypochlorite solution for 90 min or 40 kHz of ultrasound for 8 min improved germination percentage from 0 to 29.2% or to 19.7%, respectively. Plantlets that were at least 5 cm in height were transplanted to a Zhijing stone substrate for orchids, and 85.3% of plantlets survived 180 days after transplanting.
    MeSH term(s) Culture Media ; Germination ; Orchidaceae/embryology ; Orchidaceae/growth & development ; Phenotype ; Seeds/growth & development
    Chemical Substances Culture Media
    Language English
    Publishing date 2015-11-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep16356
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The effect of TiO2 nanoparticles removal on drinking water quality produced by conventional treatment C/F/S

    Serrão Sousa, Vânia / Claudia Corniuc / Margarida Ribau Teixeira

    Water research. 2016,

    2016  

    Abstract: ... coagulation/flocculation/sedimentation (C/F/S) from drinking water treatment to remove TiO2 nanoparticles (NPs ... from surface waters, and pretends to understand if the removal of TiO2 NPs affects the ability of C/F/S to remove ... ranging between 0.2 and 10 mg/L, have not a significant impact on NPs removal by C/F/S ...

    Abstract Nanoparticles, namely titanium dioxide (TiO2), are emerging contaminants widely used to commercial and industrial applications, are a potential hazard and can cause damage to environment and human health due to their toxicity. Therefore, their removal from the water is urgent to minimize or eliminate the adverse environmental and human effects. This work, investigates the efficiency of conventional coagulation/flocculation/sedimentation (C/F/S) from drinking water treatment to remove TiO2 nanoparticles (NPs) from surface waters, and pretends to understand if the removal of TiO2 NPs affects the ability of C/F/S to remove natural organic matter (NOM) and turbidity, and consequently affects the quality of the treated water.Results show that TiO2 NPs removal is high (>90%) for all the waters studied (hydrophobic and hydrophilic waters) and the treated water quality is not compromised (turbidity, Ti and Al concentrations, pH and conductivity are below the national and international guidelines). In addition, TiO2 initial concentrations, ranging between 0.2 and 10 mg/L, have not a significant impact on NPs removal by C/F/S. Therefore, the widely used polyaluminium based coagulants are effective in the removal of TiO2 NPs by conventional C/F/S treatment, but removal is strongly influenced by the water characteristics. Hydrophobic waters need a higher coagulant dose than hydrophilic waters to achieve the same TiO2 NPs removals, as well as water with higher UV254nm values. The principal mechanism involved in TiO2 NPs removal is charge neutralisation.
    Keywords aluminum ; coagulants ; coagulation ; drinking water ; environmental degradation ; flocculation ; guidelines ; human health ; humans ; hydrophilicity ; hydrophobicity ; industrial applications ; nanoparticles ; neutralization ; organic matter ; pH ; surface water ; titanium dioxide ; toxicity ; turbidity ; water quality ; water treatment
    Language English
    Size p. .
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 202613-2
    ISSN 1879-2448 ; 0043-1354
    ISSN (online) 1879-2448
    ISSN 0043-1354
    DOI 10.1016/j.watres.2016.11.030
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Mansoins CF, Oligomeric Flavonoid Glucosides Isolated from Mansoa hirsuta Fruits with Potential Anti-inflammatory Activity

    Campana, PriscillaR. V / Braga, Fernão C / Coleman, Christina M / Ferreira, Daneel / Sousa, Lirlândia P / Teixeira, Mauro M

    Journal of natural products. 2016 Sept. 23, v. 79, no. 9

    2016  

    Abstract: ... to 1,3-diarylpropane C6–C3–C6 units. The structures and absolute configurations of mansoins CF (3–6 ... were established by analysis of NMR and electronic circular dichroism data. Mansoin C (3) was ... identified as a diglucosylated heterodimer, whereas mansoins D (4), E (5), and F (6) were identified ...

    Abstract Continued investigation of the polyphenolic pool of the fruits of Mansoa hirsuta afforded four additional members of the new class of glucosylated oligomeric flavonoids comprising a flavanone core linked to 1,3-diarylpropane C6–C3–C6 units. The structures and absolute configurations of mansoins CF (3–6) were established by analysis of NMR and electronic circular dichroism data. Mansoin C (3) was identified as a diglucosylated heterodimer, whereas mansoins D (4), E (5), and F (6) were identified as triglucosylated heterotrimers, isomeric with mansoin A (1). Mansoin F (6) inhibited TNF-α release by lipopolysaccharide-stimulated THP-1 cells (IC50 of 19.3 ± 1.3 μM) and, as with mansoin A (1), reduced the phosphorylation levels of p-65-NF-κB, when assayed at 50 μM. These results indicate that the potential anti-inflammatory properties of mansoin F (6) are probably due to inhibition of the NF-κB pathway and inhibition of TNF-α release.
    Keywords anti-inflammatory activity ; circular dichroism spectroscopy ; flavanones ; fruits ; glucosides ; inhibitory concentration 50 ; nuclear magnetic resonance spectroscopy ; phosphorylation ; transcription factor NF-kappa B ; tumor necrosis factor-alpha
    Language English
    Dates of publication 2016-0923
    Size p. 2279-2286.
    Publishing place American Chemical Society and American Society of Pharmacognosy
    Document type Article
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021%2Facs.jnatprod.6b00390
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: Lack of primary mutations associated with integrase inhibitors among HIV-1 subtypes B, C, and F circulating in Brazil.

    Passaes, Caroline Bittencourt / Guimarães, Monick Lindenmeyer / Fernandez, Saada Lima Chequer / Lorete, Roberta Dos Santos / Teixeira, Sylvia Lopes Maia / Fernandez, José Carlos Couto / Morgado, Mariza Gonçalves

    Journal of acquired immune deficiency syndromes (1999)

    2009  Volume 51, Issue 1, Page(s) 7–12

    Abstract: ... polymorphisms and resistance mutations associated with IN inhibitors among HIV-1 subtypes B, C, and F samples ... by B, C, or F subtypes and plasma viral RNA from 30 subtype B-infected individuals failing highly ...

    Abstract Background: Antiretroviral drugs targeting integrase (IN) have recently been approved for use in combined and salvage therapeutic interventions.
    Objective: To evaluate the presence of natural polymorphisms and resistance mutations associated with IN inhibitors among HIV-1 subtypes B, C, and F samples obtained from drug-naive individuals and patients failing highly active antiretroviral therapy in Brazil.
    Methods: Proviral DNA was obtained from blood samples of 105 HIV-1-positive drug-naive patients infected by B, C, or F subtypes and plasma viral RNA from 30 subtype B-infected individuals failing highly active antiretroviral therapy. The IN region was amplified by nested polymerase chain reaction and automatically sequenced for subtype determination. Translated amino acid sequences were inspected for IN mutations associated with antiretroviral resistance.
    Results: Eleven mutations described as conferring in vitro resistance to IN strand transfer inhibitors were detected among the HIV-1 Brazilian samples. V72I and V201I were considered as polymorphisms. Major mutations associated with elvitegravir or raltegravir in vivo resistance (Q148K/H/R, N155H) were not detected.
    Conclusions: Although some naturally occurring polymorphisms were observed, the absence of major resistance mutations for the current IN inhibitors provides a good rationale for the introduction of these drugs in Brazil. These results highlight the importance of the continuous surveillance of IN genetic diversity.
    MeSH term(s) Amino Acid Sequence ; Brazil ; Consensus Sequence ; DNA, Viral/genetics ; DNA, Viral/isolation & purification ; Drug Resistance, Viral/genetics ; Genes, Viral ; HIV Infections/drug therapy ; HIV Infections/virology ; HIV Integrase/genetics ; HIV Integrase Inhibitors/pharmacology ; HIV-1/classification ; HIV-1/drug effects ; HIV-1/enzymology ; HIV-1/genetics ; Humans ; Molecular Sequence Data ; Mutation ; Polymerase Chain Reaction ; Polymorphism, Genetic ; Sequence Homology, Amino Acid
    Chemical Substances DNA, Viral ; HIV Integrase Inhibitors ; HIV Integrase (EC 2.7.7.-)
    Language English
    Publishing date 2009-03-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645053-2
    ISSN 1944-7884 ; 1077-9450 ; 1525-4135 ; 0897-5965 ; 0894-9255
    ISSN (online) 1944-7884 ; 1077-9450
    ISSN 1525-4135 ; 0897-5965 ; 0894-9255
    DOI 10.1097/QAI.0b013e31819df3b3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online ; E-Book: Principles of facial reconstruction

    Larrabee, Wayne F. / Sherris, David A. / Teixeira, Jeffrey C.

    a subunit approach to cutaneous repair

    2021  

    Abstract: ... by distinguished clinicians Wayne F. Larrabee Jr., David A. Sherris, Jeffrey C. Teixeira, and esteemed contributors ...

    Author's details Wayne F. Larrabee, David A. Sherris, Jeffrey C. Teixeira
    Abstract A beautifully illustrated, multimedia guide to facial soft-tissue reconstruction from leading clinicians Principles of Facial Reconstruction: A Subunit Approach to Cutaneous Repair, Third Edition by distinguished clinicians Wayne F. Larrabee Jr., David A. Sherris, Jeffrey C. Teixeira, and esteemed contributors presents evidence-based facial reconstruction techniques that simplify flap design based on location and defect. The book's primary focus is soft-tissue defects of moderate size rather than larger flap reconstructions. Building on the acclaimed prior editions, the third edition features new content and images. Key surgical principles are detailed graphically in an easy-to-navigate, concise layout. The two opening chapters cover a review of soft-tissue biomechanics and physiology, followed by fundamentals of wound closure, wound healing, grafts, and flaps. The seven consistently organized anatomic chapters present a brief overview of the anatomy of the region, followed by succinct descriptions of surgical approaches for relevant subunits in that region. The final two chapters provide details on free flaps and graft harvesting techniques. The reader-friendly format enables quick determination of the most reliable reconstruction options for repair of the scalp, forehead, eyes, nose, cheek, ears, and lips and chin. Key Features Firsthand experience from renowned experts on the most reliable defect reconstructions Full-color clinical photographs, around 500 high-quality illustrations, and diagrams provide precise insights on key surgical concepts Following a facial unit principle, decision-making algorithms guide readers on selection of the most effective flap or graft for each case This is a must-have resource for plastic surgeons, otolaryngologists, and oral-maxillofacial surgeons, and dermatology residents and fellows, as well as surgeons
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (x, 312 Seiten), Illustrationen
    Edition Third edition
    Publisher Thieme
    Publishing place New York
    Publishing country United States
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021135896
    ISBN 978-1-68420-107-5 ; 9781684201068 ; 1-68420-107-1 ; 1684201063
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  8. Article ; Online: Recycling Polyethylene/Polyamide Multilayer Films with Poly(isoprene-

    Romeiro, Andreia / Teixeira, Cidália / Costa, Henrique / Coelho, Jorge F J / Serra, Arménio C

    Polymers

    2024  Volume 16, Issue 8

    Abstract: Polymers generally form incompatible mixtures that make the process of recycling difficult, especially the mechanical recycling of mixed plastic waste. One of the most commonly used films in the packaging industry is multilayer films, mainly composed of ... ...

    Abstract Polymers generally form incompatible mixtures that make the process of recycling difficult, especially the mechanical recycling of mixed plastic waste. One of the most commonly used films in the packaging industry is multilayer films, mainly composed of polyethylene (PE) and polyamide (PA). Recycling these materials with such different molecular structures requires the use of compatibilizers to minimize phase separation and obtain more useful recycled materials. In this work, commercial polyisoprene-graft-maleic anhydride (PI-
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16081079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: The Atmosphere over Mountainous Regions

    Sheridan, Peter F. / Olafsson, Haraldur / Kirshbaum, Daniel J. / Teixeira, Miguel A. C. / Stiperski, Ivana

    2016  

    Abstract: Mountainous regions occupy a significant fraction of the Earth's continents and are characterized by specific meteorological phenomena operating on a wide range of scales. Being a home to large human populations, the impact of mountains on weather and ... ...

    Abstract Mountainous regions occupy a significant fraction of the Earth's continents and are characterized by specific meteorological phenomena operating on a wide range of scales. Being a home to large human populations, the impact of mountains on weather and hydrology has significant practical consequences. Mountains modulate the climate and create micro-climates, induce different types of thermally and dynamically driven circulations, generate atmospheric waves of various scales (known as mountain waves), and affect the boundary layer characteristics and the dispersion of pollutants. At the local scale, strong downslope winds linked with mountain waves (such as the Foehn and Bora) can cause severe damage. Mountain wave breaking in the high atmosphere is a source of Clear Air Turbulence, and lee wave rotors are a major near-surface aviation hazard.-

    Mountains also act to block strongly-stratified air layers, leading to the formation of valley cold-air pools (with implications for road safety, pollution, crop damage, etc.) and gap flows. Presently, neither the fine-scale structure of orographic precipitation nor the initiation of deep convection by mountainous terrain can be resolved adequately by regional-to global-scale models, requiring appropriate downscaling or parameterization. Additionally, the shortest mountain waves need to be parameterized in global weather and climate prediction models, because they exert a drag on the atmosphere. This drag not only decelerates the global atmospheric circulation, but also affects temperatures in the polar stratosphere, which control ozone depletion. It is likely that both mountain wave drag and orographic precipitation lead to non-trivial feedbacks in climate change scenarios.-

    Measurement campaigns such as MAP, T-REX, Materhorn, COLPEX and i-Box provided a wealth of mountain meteorology field data, which is only starting to be explored. Recent advances in computing power allow numerical simulations of unprecedented resolution, e.g. LES modelling of rotors, mountain wave turbulence, and boundary layers in mountainous regions. This will lead to important advances in understanding these phenomena, as well as mixing and pollutant dispersion over complex terrain, or the onset and breakdown of cold-air pools. On the other hand, recent analyses of global circulation biases point towards missing drag, especially in the southern hemisphere, which may be due to processes currently neglected in parameterizations. A better understanding of flow over orography is also crucial for a better management of wind power and a more effective use of data assimilation over complex terrain.-
    Keywords Science (General) ; Physical geography
    Size 1 electronic resource (160 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020097368
    ISBN 9782889450169 ; 2889450163
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Article ; Online: Glucose-Binding Dioclea bicolor Lectin (DBL): Purification, Characterization, Structural Analysis, and Antibacterial Properties.

    Reis, Willian F / Silva, Marcos E S / Gondim, Ana C S / Torres, Renato C F / Carneiro, Rômulo F / Nagano, Celso S / Sampaio, Alexandre H / Teixeira, Claudener S / Gomes, Lenita C B F / Sousa, Bruno L / Andrade, Alexandre L / Teixeira, Edson H / Vasconcelos, Mayron A

    The protein journal

    2024  

    Abstract: In this study, we purified a lectin isolated from the seeds of Dioclea bicolor (DBL) via affinity purification. Electrophoresis analysis revealed that DBL had three bands, α, β, and γ chains, with molecular masses of approximately 29, 14, and 12 kDa, ... ...

    Abstract In this study, we purified a lectin isolated from the seeds of Dioclea bicolor (DBL) via affinity purification. Electrophoresis analysis revealed that DBL had three bands, α, β, and γ chains, with molecular masses of approximately 29, 14, and 12 kDa, respectively. Gel filtration chromatography revealed that the native form of DBL had a molecular mass of approximately 100 kDa, indicating that it is a tetramer. Interestingly, DBL-induced hemagglutination was inhibited by several glucosides, mannosides, ampicillin, and tetracycline with minimum inhibitory concentration (MIC) values of 1.56-50 mM. Analysis of the complete amino acid sequence of DBL revealed the presence of 237 amino acids with high similarity to other Diocleinae lectins. Circular dichroism showed the prominent β-sheet secondary structure of DBL. Furthermore, DBL structure prediction revealed a Discrete Optimized Protein Energy (DOPE) score of -26,642.69141/Normalized DOPE score of -1.84041. The DBL monomer was found to consist a β-sandwich based on its 3D structure. Molecular docking showed the interactions between DBL and α-D-glucose, N-acetyl-D-glucosamine, α-D-mannose, α-methyl-D-mannoside, ampicillin, and tetracycline. In addition, DBL showed antimicrobial activity with an MIC of 125 μg/mL and exerted synergistic effects in combination with ampicillin and tetracycline (fractional inhibitory concentration index ≤ 0.5). Additionally, DBL significantly inhibited biofilm formation and showed no toxicity in murine fibroblasts (p < 0.05). These results suggest that DBL exhibits antimicrobial activity and works synergistically with antibiotics.
    Language English
    Publishing date 2024-04-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2143071-8
    ISSN 1875-8355 ; 1572-3887
    ISSN (online) 1875-8355
    ISSN 1572-3887
    DOI 10.1007/s10930-024-10199-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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