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  1. Article ; Online: Increasing Evidence That Diagnostic Stewardship May Improve Antibiotic Use.

    Morgan, Daniel J / Leekha, Surbhi / Claeys, Kimberly C

    JAMA internal medicine

    2023  Volume 183, Issue 9, Page(s) 942–943

    MeSH term(s) Humans ; Anti-Bacterial Agents/therapeutic use ; Antimicrobial Stewardship
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-07-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2023.2756
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  2. Article ; Online: Hospital-onset bacteremia and fungemia: examining healthcare-associated infections prevention through a wider lens.

    Schrank, Gregory M / Snyder, Graham M / Leekha, Surbhi

    Antimicrobial stewardship & healthcare epidemiology : ASHE

    2023  Volume 3, Issue 1, Page(s) e198

    Abstract: A hospital-onset bacteremia and fungemia (HOB) metric will expand hospital surveillance of bloodstream infections beyond current state and provide an opportunity to re-evaluate infection prevention strategies. Here we consider the added value and ... ...

    Abstract A hospital-onset bacteremia and fungemia (HOB) metric will expand hospital surveillance of bloodstream infections beyond current state and provide an opportunity to re-evaluate infection prevention strategies. Here we consider the added value and potential pitfalls of HOB surveillance and present a framework for the standardized assessment of HOB events.
    Language English
    Publishing date 2023-11-08
    Publishing country England
    Document type Journal Article
    ISSN 2732-494X
    ISSN (online) 2732-494X
    DOI 10.1017/ash.2023.486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hospital-onset bacteremia and fungemia

    Gregory M. Schrank / Graham M. Snyder / Surbhi Leekha

    Antimicrobial Stewardship & Healthcare Epidemiology, Vol

    examining healthcare-associated infections prevention through a wider lens

    2023  Volume 3

    Abstract: A hospital-onset bacteremia and fungemia (HOB) metric will expand hospital surveillance of bloodstream infections beyond current state and provide an opportunity to re-evaluate infection prevention strategies. Here we consider the added value and ... ...

    Abstract A hospital-onset bacteremia and fungemia (HOB) metric will expand hospital surveillance of bloodstream infections beyond current state and provide an opportunity to re-evaluate infection prevention strategies. Here we consider the added value and potential pitfalls of HOB surveillance and present a framework for the standardized assessment of HOB events.
    Keywords Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Reply to McFarland et al.

    Heil, Emily / Harris, Anthony / Leekha, Surbhi

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2021  Volume 74, Issue 5, Page(s) 942–943

    Language English
    Publishing date 2021-07-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciab619
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  5. Article ; Online: Association between level of care and colonization with resistant gram-negative bacteria among nursing-home residents - CORRIGENDUM.

    Adediran, Timileyin Y / Sethuraman, Kinjal N / Leekha, Surbhi / Roghmann, Mary-Claire

    Infection control and hospital epidemiology

    2022  Volume 44, Issue 7, Page(s) 1207

    MeSH term(s) Humans ; Gram-Negative Bacteria ; Nursing Homes ; Risk Factors ; Gram-Negative Bacterial Infections
    Language English
    Publishing date 2022-07-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2022.177
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  6. Article ; Online: Evaluation of an antigen-test-based strategy to reduce duration of transmission-based precautions for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection in hospitalized patients.

    Schrank, Gregory M / Harris-Williams, Michelle / Schiavone, Kelly / Lusby, Martha C / Dove, Cindy / Leekha, Surbhi

    Infection control and hospital epidemiology

    2023  Volume 45, Issue 1, Page(s) 114–116

    Abstract: An academic hospital implemented a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) antigen-test-based strategy to facilitate discontinuation of precautions for patients admitted with a positive SARS-CoV-2 test. Of 171 patients that underwent ... ...

    Abstract An academic hospital implemented a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) antigen-test-based strategy to facilitate discontinuation of precautions for patients admitted with a positive SARS-CoV-2 test. Of 171 patients that underwent antigen testing, 68% had an initial negative test performed a median of 5 days after admission. Antigen testing reduced isolation time by 144 hours.
    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19/diagnosis ; COVID-19/prevention & control ; Infection Control
    Language English
    Publishing date 2023-08-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2023.164
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  7. Article: Crossroads of Antimicrobial and Diagnostic Stewardship: Assessing Risks to Develop Clinical Decision Support to Combat Multidrug-Resistant

    Zou, Iris / Abate, Daniel / Newman, Michelle / Heil, Emily L / Leekha, Surbhi / Claeys, Kimberly C

    Open forum infectious diseases

    2023  Volume 10, Issue 10, Page(s) ofad512

    Abstract: Background: Early detection of multidrug-resistant : Methods: This was a mixed-methods study. We conducted a split-sample cohort study of adult critical care patients with : Results: The 2 previous risk prediction tools demonstrated similar ... ...

    Abstract Background: Early detection of multidrug-resistant
    Methods: This was a mixed-methods study. We conducted a split-sample cohort study of adult critical care patients with
    Results: The 2 previous risk prediction tools demonstrated similar accuracy in the derivation cohort (c-statistic of 0.76 [95% confidence interval {CI}, .69-.83] and 0.73 [95% CI, .66-.8]). A simplified tool based on 4 variables demonstrated reasonable accuracy (c-statistic of 0.71 [95% CI, .57-.85]) without significant overprescribing in the validation cohort. The risk factors were prior MDRP infection, ≥4 antibiotics prior to culture, infection >3 days after admission, and dialysis. Fourteen clinicians completed the survey. An alert providing context regarding individual patient risk factors for MDRP was preferred.
    Conclusions: These results can be used to develop a local EMR-integrated tool to improve timeliness of effective therapy in those at risk of MDRP infections.
    Language English
    Publishing date 2023-10-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofad512
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  8. Article ; Online: Perceptions of Health Care-Associated Infection Metrics by Infection Control Experts.

    Schrank, Gregory M / Branch-Elliman, Westyn / Leekha, Surbhi / Baghdadi, Jonathan / Pineles, Lisa / Harris, Anthony D / Morgan, Daniel J

    JAMA network open

    2023  Volume 6, Issue 4, Page(s) e238952

    MeSH term(s) Humans ; Benchmarking ; Cross Infection/prevention & control ; Infection Control ; Delivery of Health Care
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2023.8952
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  9. Article ; Online: Recurrent central-line-associated bloodstream infection in a single high-risk patient.

    Pek, Zachary / Canepa, Hannah / Gregg, Karen L / Cabunoc, Marie K / Leekha, Surbhi / Baghdadi, Jonathan D

    Infection control and hospital epidemiology

    2022  Volume 44, Issue 1, Page(s) 166–168

    MeSH term(s) Humans ; Catheterization, Central Venous ; Cross Infection/epidemiology ; Sepsis ; Catheter-Related Infections ; Central Venous Catheters ; Bacteremia
    Language English
    Publishing date 2022-08-01
    Publishing country United States
    Document type Research Support, N.I.H., Extramural ; Letter
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2022.190
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  10. Article ; Online: Association between level of care and colonization with resistant gram-negative bacteria among nursing-home residents.

    Adediran, Timileyin Y / Sethuraman, Kinjal N / Leekha, Surbhi / Roghmann, Mary-Claire

    Infection control and hospital epidemiology

    2021  Volume 42, Issue 6, Page(s) 760–762

    Abstract: In this cross-sectional study, we examined the relationship between resident level of care in the nursing home and colonization with resistant gram-negative bacteria. Residential-care residents were more likely to be colonized with resistant gram- ... ...

    Abstract In this cross-sectional study, we examined the relationship between resident level of care in the nursing home and colonization with resistant gram-negative bacteria. Residential-care residents were more likely to be colonized with resistant gram-negative bacteria than were postacute care residents (odds ratio, 2.3; 95% confidence interval, 1.40-3.80; P < .001).
    MeSH term(s) Cross-Sectional Studies ; Gram-Negative Bacteria ; Gram-Negative Bacterial Infections/epidemiology ; Humans ; Nursing Homes ; Risk Factors
    Language English
    Publishing date 2021-03-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2020.1274
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