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Article ; Online: Achieving Cardiovascular Risk Management Goals and Patient Quality of Life.

Kosobucka-Ozdoba, Agata / Pietrzykowski, Łukasz / Michalski, Piotr / Ratajczak, Jakub / Grzelakowska, Klaudyna / Kasprzak, Michał / Kubica, Jacek / Kubica, Aldona

Journal of cardiovascular development and disease

2024 Volume 11, Issue 2

Abstract: 1) Background: Eliminating or reducing the severity of modifiable risk factors of cardiovascular disease (CVD) and undertaking health-promoting behaviors is the basis for prevention. (2) Methods: This study included 200 subjects without a history of CVD, ...

Abstract	(1) Background: Eliminating or reducing the severity of modifiable risk factors of cardiovascular disease (CVD) and undertaking health-promoting behaviors is the basis for prevention. (2) Methods: This study included 200 subjects without a history of CVD, aged 18 to 80 years, who had been diagnosed with hypertension, hypercholesterolemia, or diabetes 6 to 24 months before study enrolment. (3) Results: The median 10-year CV risk assessed by the SCORE2 and SCORE2-OP algorithms was 3.0 (IQR 1.5-7.0). An increase in mean cardiovascular risk in the range from low and moderate to very high was associated with a decrease in quality of life both in individual subscales and the overall score. The median number of controlled risk factors was 4.0 (IQR 3.0-5.0). As the mean number of controlled risk factors increased, the quality of life improved in both of HeartQoL questionnaire subscales (emotional
Language	English
Publishing date	2024-01-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2777082-5
ISSN	2308-3425 ; 2308-3425
ISSN (online)	2308-3425
ISSN	2308-3425
DOI	10.3390/jcdd11020045
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Gender-Related Effectiveness of Personalized Post-COVID-19 Rehabilitation.

Rzepka-Cholasińska, Alicja / Ratajczak, Jakub / Michalski, Piotr / Kasprzak, Michał / Kosobucka-Ozdoba, Agata / Pietrzykowski, Łukasz / Grzelakowska, Klaudyna / Kubica, Jacek / Kryś, Jacek / Kubica, Aldona

Journal of clinical medicine

2024 Volume 13, Issue 4

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2024-02-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm13040938
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Article: Occurrence and Temporal Variability of Out-of-Hospital Cardiac Arrest during COVID-19 Pandemic in Comparison to the Pre-Pandemic Period in Poland-Observational Analysis of OSCAR-POL Registry.

Ratajczak, Jakub / Szczerbiński, Stanisław / Kubica, Aldona

Journal of clinical medicine

2022 Volume 11, Issue 14

Abstract: An investigation of the chronobiology of out-of-hospital cardiac arrest (OHCA) during the coronavirus disease 2019 (COVID-19) pandemic and the differences in comparison to the 6-year pre-pandemic period. A retrospective analysis of the dispatch cards ... ...

Abstract	An investigation of the chronobiology of out-of-hospital cardiac arrest (OHCA) during the coronavirus disease 2019 (COVID-19) pandemic and the differences in comparison to the 6-year pre-pandemic period. A retrospective analysis of the dispatch cards from the Emergency Medical Service between January 2014 and December 2020 was performed within the OSCAR-POL registry. The circadian, weekly, monthly, and seasonal variabilities of OHCA were investigated. A comparison of OHCA occurrence between the year 2020 and the 6-year pre-pandemic period was made. A total of 416 OHCAs were reported in 2020 and the median of OHCAs during the pre-pandemic period was 379 (interquartile range 337−407) cases per year. Nighttime was associated with a decreased number of OHCAs (16.6%) in comparison to afternoon (31.5%, p < 0.001) and morning (30.0%, p < 0.001). A higher occurrence at night was observed in 2020 compared to 2014−2019 (16.6% vs. 11.7%, p = 0.001). Monthly and seasonal variabilities were observed in 2020. The months with the highest OHCA occurrence in 2020 were November (13.2%) and October (11.1%) and were significantly higher compared to the same months during the pre-pandemic period (9.1%, p = 0.002 and 7.9%, p = 0.009, respectively). Autumn was the season with the highest rate of OHCA, which was also higher compared to the pre-pandemic period (30.5% vs. 25.1%, p = 0.003). The COVID-19 pandemic was related to a higher occurrence of OHCA. The circadian, monthly, and seasonal variabilities of OHCA occurrence were confirmed. In 2020, the highest occurrence of OHCA was observed in October and November, which coincided with the highest occurrence of COVID-19 infections in Poland.
Language	English
Publishing date	2022-07-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11144143
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Article ; Online: Observational analysiS of out-of-hospital Cardiac Arrest occurRence and temporal variability patterns in subpopulation of southern POLand from 2006 to 2018: OSCAR-POL registry.

Szczerbiński, Stanisław / Ratajczak, Jakub / Jasiewicz, Małgorzata / Kubica, Aldona

Cardiology journal

2021 Volume 30, Issue 4, Page(s) 567–575

Abstract: Background: Temporal variability of out-of-hospital cardiac arrest (OHCA) occurrence was presented in previous studies, however, the data regarding long-term observation is scarce. The aim of this study was to investigate the temporal variability of ... ...

Abstract	Background: Temporal variability of out-of-hospital cardiac arrest (OHCA) occurrence was presented in previous studies, however, the data regarding long-term observation is scarce. The aim of this study was to investigate the temporal variability of OHCA occurrence during a long-time period and analyze the circadian pattern within particular timeframes. Methods: The retrospective analysis of 5058 OHCA cases was made covering the period from January 1st, 2006 to December 31st, 2018. Circadian, weekly, monthly and seasonal variabilities were investigated. The circadian variability of OHCA occurrence was assessed within particular years, seasons of the year, and days of the week. Results: The highest OHCA incidence was observed between 08:00 and 08:59 and the lowest between 01:00 and 01:59 (7.1% vs. 1.6%, p < 0.001). After division into 6-h intervals, a significantly lower number of OHCA cases occurred between 00:00 and 05:59 (12.3%) in comparison to the highest number observed in between 06:00 and 11:59 (12.3% vs. 33.5%, p < 0.001). The highest OHCA occurrence was observed on Monday (14.9%), however, no weekly variability was found (p = 0.557). The highest OHCA occurrence was observed in the winter and lowest in the summer (27.4% vs. 22.8%, p < 0.001). Significant circadian variability was observed for every day of the week, every season and year during the observation period (p < 0.001). Conclusions: Circadian, monthly and seasonal variability of OHCA occurrence was confirmed in the long-term observation with no differences between particular days of the week. Significant circadian variability was observed within days of the week, seasons of the year, and particular years.
MeSH term(s)	Humans ; Out-of-Hospital Cardiac Arrest/diagnosis ; Out-of-Hospital Cardiac Arrest/epidemiology ; Out-of-Hospital Cardiac Arrest/therapy ; Poland/epidemiology ; Registries ; Retrospective Studies ; Time Factors
Language	English
Publishing date	2021-07-27
Publishing country	Poland
Document type	Journal Article ; Observational Study
ZDB-ID	2488680-4
ISSN	1898-018X ; 1897-5593
ISSN (online)	1898-018X
ISSN	1897-5593
DOI	10.5603/CJ.a2021.0060
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Article: Effects of Multidisciplinary Rehabilitation Program in Patients with Long COVID-19: Post-COVID-19 Rehabilitation (PCR SIRIO 8) Study.

Ostrowska, Małgorzata / Rzepka-Cholasińska, Alicja / Pietrzykowski, Łukasz / Michalski, Piotr / Kosobucka-Ozdoba, Agata / Jasiewicz, Małgorzata / Kasprzak, Michał / Kryś, Jacek / Kubica, Aldona

Journal of clinical medicine

2023 Volume 12, Issue 2

Abstract: Up to 80% of COVID-19 survivors experience prolonged symptoms known as long COVID-19. The aim of this study was to evaluate the effects of a multidisciplinary rehabilitation program in patients with long COVID-19. The rehabilitation program was composed ... ...

Abstract	Up to 80% of COVID-19 survivors experience prolonged symptoms known as long COVID-19. The aim of this study was to evaluate the effects of a multidisciplinary rehabilitation program in patients with long COVID-19. The rehabilitation program was composed of physical training (aerobic, resistance, and breathing exercises), education, and group psychotherapy. After 6 weeks of rehabilitation in 97 patients with long COVID-19, body composition analysis revealed a significant decrease of abdominal fatty tissue (from 2.75 kg to 2.5 kg; p = 0.0086) with concomitant increase in skeletal muscle mass (from 23.2 kg to 24.2 kg; p = 0.0104). Almost 80% of participants reported dyspnea improvement assessed with the modified Medical Research Council scale. Patients’ physical capacity assessed with the 6 Minute Walking Test increased from 320 to 382.5 m (p < 0.0001), the number of repetitions in the 30 s Chair Stand Test improved from 13 to 16 (p < 0.0001), as well as physical fitness in the Short Physical Performance Battery Test from 14 to 16 (p < 0.0001). The impact of fatigue on everyday functioning was reduced in the Modified Fatigue Impact Scale from 37 to 27 (p < 0.0001). Cardiopulmonary exercise test did not show any change. The multidisciplinary rehabilitation program has improved body composition, dyspnea, fatigue and physical capacity in long COVID-19 patients.
Language	English
Publishing date	2023-01-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12020420
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Article ; Online: Andexanet alfa - Recommendations for clinical use. Multidisciplinary experts' standpoint.

Kubica, Jacek / Adamski, Piotr / Gajda, Robert / Gąsior, Mariusz / Gierlotka, Marek / Gil, Robert / Jaguszewski, Miłosz / Kubica, Aldona / Kuliczkowski, Wiktor / Kurek, Krzysztof / Ładny, Jerzy Robert / Michalski, Piotr / Navarese, Eliano Pio / Niezgoda, Piotr / Ostrowska, Małgorzata / Tycińska, Agnieszka

Cardiology journal

2023 Volume 30, Issue 4, Page(s) 502–505

MeSH term(s)	Humans ; Blood Coagulation ; Anticoagulants/adverse effects ; Factor Xa/pharmacology
Chemical Substances	PRT064445 ; Anticoagulants ; Factor Xa (EC 3.4.21.6)
Language	English
Publishing date	2023-07-04
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2488680-4
ISSN	1898-018X ; 1897-5593
ISSN (online)	1898-018X
ISSN	1897-5593
DOI	10.5603/CJ.a2023.0043
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Article ; Online: IMPACT of PCSK9 inhibition on clinical outcome in patients during the inflammatory stage of the SARS-COV-2 infection: Rationale and protocol of the IMPACT-SIRIO 5 study.

Kubica, Jacek / Podhajski, Przemysław / Magielski, Przemysław / Kubica, Aldona / Adamski, Piotr / Junik, Roman / Pinkas, Jarosław / Navarese, Eliano P

Cardiology journal

2021 Volume 29, Issue 1, Page(s) 140–147

MeSH term(s)	COVID-19 ; Carbidopa ; Drug Combinations ; Humans ; Levodopa/analogs & derivatives ; Proprotein Convertase 9 ; SARS-CoV-2
Chemical Substances	Drug Combinations ; sirio ; Levodopa (46627O600J) ; PCSK9 protein, human (EC 3.4.21.-) ; Proprotein Convertase 9 (EC 3.4.21.-) ; Carbidopa (MNX7R8C5VO)
Language	English
Publishing date	2021-11-17
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2488680-4
ISSN	1898-018X ; 1897-5593
ISSN (online)	1898-018X
ISSN	1897-5593
DOI	10.5603/CJ.a2021.0148
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Article: Determinants of Lipid Parameters in Patients without Diagnosed Cardiovascular Disease-Results of the Polish Arm of the EUROASPIRE V Survey.

Ratajczak, Jakub / Kubica, Aldona / Michalski, Piotr / Pietrzykowski, Łukasz / Białczyk, Aleksandra / Kosobucka-Ozdoba, Agata / Bergmann, Katarzyna / Buczkowski, Krzysztof / Krintus, Magdalena / Jankowski, Piotr / Kubica, Jacek

Journal of clinical medicine

2023 Volume 12, Issue 7

Abstract: To assess the determinants of lipid parameters in primary care patients without diagnosed cardiovascular disease (CVD), a cross-sectional study was conducted during 2018-2019 with a total of 200 patients. The following lipid parameters were measured: ... ...

Abstract	To assess the determinants of lipid parameters in primary care patients without diagnosed cardiovascular disease (CVD), a cross-sectional study was conducted during 2018-2019 with a total of 200 patients. The following lipid parameters were measured: total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), small, dense LDL (sdLDL-C), and lipoprotein (a) (Lp(a)). Predictors of elevated and adequately controlled lipid parameters were assessed with logistic regression analysis. Older age was related to higher risk of TC ≥ 6.2 mmol/L [OR 1.03 (95% CI 1.0-1.05)], sdLDL-C ≥ 1.0 mmol/L [OR 1.05 (95% CI 1.0-1.1)], and decreased risk of Lp(a) ≥ 50 mg/dL [OR 0.97 (95% CI 0.94-0.99)]. Patients with diabetes mellitus (DM) had increased probability of TG ≥ 2.25 mmol/L [OR 3.77 (95% CI 1.34-10.6)] and Lp(a) ≥ 50 mg/dL [OR 2.97 (1.34-6.10)] as well as adequate control of TG and Lp(a). Higher material status was related to lower risk of TC ≥ 6.2 mmol/L [OR 0.19 (95% CI 0.04-0.82)] and LDL-C ≥ 3.6 mmol/L [OR 0.33 (95% CI 0.12-0.92)]. High BMI was related to increased [OR 1.14 (95% CI 1.02-1.29)], and female gender [OR 0.33 (95% CI 0.12-0.96)] and hypertension [OR 0.29 (95% CI 0.1-0.87)] to decreased risk of TG ≥ 2.25 mmol/L [OR 1.14 (95% CI 1.02-1.29)]. Taking lipid-lowering drugs (LLD) was associated with LDL-C < 2.6 mmol/L [OR 2.1 (95% CI 1.05-4.19)] and Lp(a) < 30 mg/dL [OR 0.48 (95% CI 0.25-0.93)]. Physical activity was related to LDL-C < 2.6 mmol/L [OR 2.02 (95% CI 1.02-3.98)]. Higher abdominal circumference was associated with decreased risk of TG < 1.7 mmol/L [OR 0.96 (95% CI 0.93-0.99)]. Elevated lipid parameters were related to age, gender, material status, BMI, history of DM, and hypertension. Adequate control was associated with age, education, physical activity, LLD, history of DM, and abdominal circumference.
Language	English
Publishing date	2023-04-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12072738
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Article ; Online: The influence of patient expectations on adherence to treatment regimen after myocardial infarction.

Pietrzykowski, Łukasz / Kasprzak, Michał / Michalski, Piotr / Kosobucka, Agata / Fabiszak, Tomasz / Kubica, Aldona

Patient education and counseling

2021 Volume 105, Issue 2, Page(s) 426–431

Abstract: Objective: In-hospital patient education is one of the elements affecting patient adherence to treatment regimen after myocardial infarction (MI). Its effectiveness is determined by educator and patient-dependent factors. Previous studies did not ... ...

Abstract	Objective: In-hospital patient education is one of the elements affecting patient adherence to treatment regimen after myocardial infarction (MI). Its effectiveness is determined by educator and patient-dependent factors. Previous studies did not identify patient expectations as an independent determinant of successful education. The aim of this study was to assess whether patient knowledge and expectations affect adherence to treatment regimen in a 1-year follow-up. Methods: This was a single-center, cohort study with a 1-year follow-up. Patient knowledge and expectations were evaluated using the Readiness for Hospital Discharge after Myocardial Infarction Scale (RHD-MIS scale). Medication adherence (including angiotensin converting enzyme inhibitors (ACEI), P2Y12 receptor inhibitors and statins) was verified based on prescription refill data extracted from The National Health Fund database. Results: The study included 225 patients aged 30-91 years (mean age 62.9 ± 11.9 years). In the 4th quarter of follow-up, patients with the highest expectations had lower adherence regarding ACEI (p = 0.01), P2Y12 receptor inhibitors (p = 0.03) and the combination of all three analysed medications (p = 0.003). Conclusions: The initial results suggest presence of a relationship between patient expectations and long-term adherence to treatment. Practice implications: Post-MI patient education directed at fulfilling or modification of patient expectations could possibly improve execution of treatment regimen.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Cohort Studies ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Medication Adherence ; Middle Aged ; Motivation ; Myocardial Infarction/drug therapy
Chemical Substances	Angiotensin-Converting Enzyme Inhibitors ; Hydroxymethylglutaryl-CoA Reductase Inhibitors
Language	English
Publishing date	2021-05-23
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	605590-4
ISSN	1873-5134 ; 0738-3991
ISSN (online)	1873-5134
ISSN	0738-3991
DOI	10.1016/j.pec.2021.05.030
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Book: Edukacja zdrowotna na tle wybranych czynników a skuteczność terapii antyagregacyjnej u pacjentów po zawale serca

Kubica, Aldona

(Rozprawa habilitacyjna / Uniwersytet Mikołaja Kopernika)

2012

Author's details	Aldona Kubica
Series title	Rozprawa habilitacyjna / Uniwersytet Mikołaja Kopernika
MeSH term(s)	Myocardial Infarction/drug therapy ; Platelet Aggregation Inhibitors ; Health Education
Language	Polish
Size	221 pages :, illustrations.
Document type	Book
Note	Originally presented as the author's thesis (dr habil.) -- Uniwersytet Mikołaja Kopernika w Toruniu.
ISBN	9788323128670 ; 8323128677
Database	Catalogue of the US National Library of Medicine (NLM)

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