LIVIVO - Search results -

Search results

Result 1 - 10 of total 70

Search options

Article ; Online: Candidate biomarkers of antibiotic resistance for the monitoring of wastewater and the downstream environment.

Teixeira, A Margarida / Vaz-Moreira, Ivone / Calderón-Franco, David / Weissbrodt, David / Purkrtova, Sabina / Gajdos, Stanislav / Dottorini, Giulia / Nielsen, Per Halkjær / Khalifa, Leron / Cytryn, Eddie / Bartacek, Jan / Manaia, Célia M

Water research

2023 Volume 247, Page(s) 120761

Abstract: Urban wastewater treatment plants (UWTPs) are essential for reducing the pollutants load and protecting water bodies. However, wastewater catchment areas and UWTPs emit continuously antibiotic resistant bacteria (ARB) and antibiotic resistance genes ( ... ...

Abstract	Urban wastewater treatment plants (UWTPs) are essential for reducing the pollutants load and protecting water bodies. However, wastewater catchment areas and UWTPs emit continuously antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs), with recognized impacts on the downstream environments. Recently, the European Commission recommended to monitor antibiotic resistance in UWTPs serving more than 100 000 population equivalents. Antibiotic resistance monitoring in environmental samples can be challenging. The expected complexity of these systems can jeopardize the interpretation capacity regarding, for instance, wastewater treatment efficiency, impacts of environmental contamination, or risks due to human exposure. Simplified monitoring frameworks will be essential for the successful implementation of analytical procedures, data analysis, and data sharing. This study aimed to test a set of biomarkers representative of ARG contamination, selected based on their frequent human association and, simultaneously, rare presence in pristine environments. In addition to the 16S rRNA gene, ten potential biomarkers (intI1, sul1, ermB, ermF, aph(3'')-Ib, qacEΔ1, uidA, mefC, tetX, and crAssphage) were monitored in DNA extracts (n = 116) from raw wastewater, activated sludge, treated wastewater, and surface water (upstream and downstream of UWTPs) samples collected in the Czech Republic, Denmark, Israel, the Netherlands, and Portugal. Each biomarker was sensitive enough to measure decreases (on average by up to 2.5 log-units gene copy/mL) from raw wastewater to surface water, with variations in the same order of magnitude as for the 16S rRNA gene. The use of the 10 biomarkers allowed the typing of water samples whose origin or quality could be predicted in a blind test. The results show that, based on appropriate biomarkers, qPCR can be used for a cost-effective and technically accessible approach to monitoring wastewater and the downstream environment.
MeSH term(s)	Humans ; Wastewater ; Genes, Bacterial ; RNA, Ribosomal, 16S/genetics ; Angiotensin Receptor Antagonists/analysis ; Angiotensin-Converting Enzyme Inhibitors/analysis ; Drug Resistance, Microbial/genetics ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/analysis ; Water/analysis
Chemical Substances	Wastewater ; RNA, Ribosomal, 16S ; Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Anti-Bacterial Agents ; Water (059QF0KO0R)
Language	English
Publishing date	2023-10-19
Publishing country	England
Document type	Journal Article
ZDB-ID	202613-2
ISSN	1879-2448 ; 0043-1354
ISSN (online)	1879-2448
ISSN	0043-1354
DOI	10.1016/j.watres.2023.120761
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 78/260: Show issues
Z 3381: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Activated tissue resident memory T-cells (CD8+CD103+CD39+) uniquely predict survival in left sided "immune-hot" colorectal cancers.

Talhouni, Shahd / Fadhil, Wakkas / Mongan, Nigel P / Field, Lara / Hunter, Kelly / Makhsous, Sogand / Maciel-Guerra, Alexandre / Kaur, Nayandeep / Nestarenkaite, Ausrine / Laurinavicius, Arvydas / Willcox, Benjamin E / Dottorini, Tania / Spendlove, Ian / Jackson, Andrew M / Ilyas, Mohammad / Ramage, Judith M

Frontiers in immunology

2023 Volume 14, Page(s) 1057292

Abstract: Introduction: Characterization of the tumour immune infiltrate (notably CD8+ T-cells) has strong predictive survival value for cancer patients. Quantification of CD8 T-cells alone cannot determine antigenic experience, as not all infiltrating T-cells ... ...

Abstract	Introduction: Characterization of the tumour immune infiltrate (notably CD8+ T-cells) has strong predictive survival value for cancer patients. Quantification of CD8 T-cells alone cannot determine antigenic experience, as not all infiltrating T-cells recognize tumour antigens. Activated tumour-specific tissue resident memory CD8 T-cells (T Methods: A comprehensive series of 1000 colorectal cancer (CRC) were arrayed on a tissue microarray, with representative cores from three tumour locations and the adjacent normal mucosa. Using multiplex immunohistochemistry we quantified and determined the localization of T Results: Across all patients, activated T Conclusion: The presence of high intra-tumoural CD8 T-cells alone is not a predictor of survival in left-sided CRC and potentially risks under treatment of patients. Measuring both high tumour-associated T
MeSH term(s)	Humans ; Memory T Cells ; Immunologic Memory ; CD8-Positive T-Lymphocytes ; Colorectal Neoplasms
Language	English
Publishing date	2023-05-11
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2023.1057292
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Transcriptional plasticity buffers genetic variation in zinc homeostasis.

Pita-Barbosa, Alice / Ricachenevsky, Felipe K / Wilson, Michael / Dottorini, Tania / Salt, David E

Scientific reports

2019 Volume 9, Issue 1, Page(s) 19482

Abstract: In roots of Arabidopsis thaliana, Zn can be either loaded into the xylem for translocation to the shoot or stored in vacuoles. Vacuolar storage is achieved through the action of the Zn/Cd transporter HMA3 (Heavy Metal Atpase 3). The Col-0 accession has ... ...

Abstract	In roots of Arabidopsis thaliana, Zn can be either loaded into the xylem for translocation to the shoot or stored in vacuoles. Vacuolar storage is achieved through the action of the Zn/Cd transporter HMA3 (Heavy Metal Atpase 3). The Col-0 accession has an HMA3 loss-of-function allele resulting in high shoot Cd, when compared to accession CSHL-5 which has a functional allele and low shoot Cd. Interestingly, both Col-0 and CSHL-5 have similar shoot Zn concentrations. We hypothesize that plants sense changes in cytosolic Zn that are due to variation in HMA3 function, and respond by altering expression of genes related to Zn uptake, transport and compartmentalisation, in order to maintain Zn homeostasis. The expression level of genes known to be involved in Zn homeostasis were quantified in both wild-type Col-0 and Col-0::HMA3
MeSH term(s)	Arabidopsis/genetics ; Arabidopsis/metabolism ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Gene Expression Regulation, Plant/genetics ; Gene Expression Regulation, Plant/physiology ; Genetic Variation/genetics ; Genetic Variation/physiology ; Zinc/metabolism
Chemical Substances	Arabidopsis Proteins ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2019-12-20
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-019-55736-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Right putamen and age are the most discriminant features to diagnose Parkinson's disease by using

Cascianelli, S / Tranfaglia, C / Fravolini, M L / Bianconi, F / Minestrini, M / Nuvoli, S / Tambasco, N / Dottorini, M E / Palumbo, B

Hellenic journal of nuclear medicine

2018 Volume 20 Suppl, Page(s) 165

Abstract: Objective: The differential diagnosis of Parkinson's disease (PD) and other conditions, such as essential tremor and drug-induced parkinsonian syndrome or normal aging brain, represents a diagnostic challenge. : Subjects and method: We ... ...

Abstract	Objective: The differential diagnosis of Parkinson's disease (PD) and other conditions, such as essential tremor and drug-induced parkinsonian syndrome or normal aging brain, represents a diagnostic challenge. Subjects and method: We retrospectively investigated 187 patients undergoing Results: For CIT, the probability of correct classification in patients with PD was 84.19±11.67% (mean±SD) and in N patients 93.48±6.95%. For CIT, the first decision rule provided a value for the right putamen of 2.32±0.16. This means that patients with right putamen values <2.32 were classified as having PD. Patients with putamen values ≥2.32 underwent further analysis. They were classified as N if the right putamen uptake value was ≥3.02 or if the value for the right putamen was <3.02 and the age was ≥67.5 years. Otherwise the patients were classified as having PD. Other similar rules on the values of both caudate nuclei and left putamen could be used to refine the classification, but in our data analysis of these data did not significantly contribute to the differential diagnosis. This could be due to an increased number of more severe patients with initial prevalence of left clinical symptoms having a worsening in right putamen uptake distribution. Conclusion: These results show that CIT was able to accurately classify PD and non-PD patients by means of
MeSH term(s)	Age Factors ; Aged ; Aged, 80 and over ; Female ; Humans ; Image Processing, Computer-Assisted ; Male ; Middle Aged ; Neural Networks (Computer) ; Parkinson Disease/diagnostic imaging ; Putamen/diagnostic imaging ; Tomography, Emission-Computed, Single-Photon ; Tropanes
Chemical Substances	Tropanes ; 2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane (155797-99-2)
Language	English
Publishing date	2018-01-11
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2186026-9
ISSN	1790-5427 ; 1108-1430
ISSN	1790-5427 ; 1108-1430
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6058: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Differentiated thyroid carcinoma in childhood.

Dottorini, M E

Rays

2000 Volume 25, Issue 2, Page(s) 245–255

Abstract: Differentiated thyroid carcinoma is rare in childhood and shows different characteristics as compared to thyroid carcinoma in adults. The male/female ratio is different, it has a higher aggressiveness, locoregional and distant metastases are frequent, ... ...

Abstract	Differentiated thyroid carcinoma is rare in childhood and shows different characteristics as compared to thyroid carcinoma in adults. The male/female ratio is different, it has a higher aggressiveness, locoregional and distant metastases are frequent, response to surgery and 131I radioiodine therapy is optimal. A better knowledge of these characteristics has resulted in the understanding of some relevant aspects of the pathogenesis and natural history of the disease, the suitability of the therapeutic approach and the incidence of adverse side-effects. The increased incidence of differentiated thyroid carcinoma in childhood following the Chernobyl nuclear accident of April 1986 renewed the interest of the scientific community and the public opinion and allowed an in-depth study of some important aspects correlated with the carcinogenic effect of ionizing radiation.
MeSH term(s)	Adolescent ; Carcinoma/diagnosis ; Carcinoma/epidemiology ; Carcinoma/therapy ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Iodine Radioisotopes/therapeutic use ; Male ; Risk Factors ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/epidemiology ; Thyroid Neoplasms/therapy ; USSR/epidemiology
Chemical Substances	Iodine Radioisotopes
Language	Italian
Publishing date	2000-04
Publishing country	Italy
Document type	Journal Article ; Review
ZDB-ID	433401-2
ISSN	0390-7740
ISSN	0390-7740
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1361: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Transplant-ineligible newly diagnosed multiple myeloma: Current and future approaches to clinical care: A Young International Society of Geriatric Oncology Review Paper.

Grant, Shakira J / Mian, Hira S / Giri, Smith / Boutin, Melina / Dottorini, Lorenzo / Neuendorff, Nina R / Krok-Schoen, Jessica L / Nikita, Nikita / Rosko, Ashley E / Wildes, Tanya M / Zweegman, Sonja

Journal of geriatric oncology

2020 Volume 12, Issue 4, Page(s) 499–507

Abstract: ... risk cytogenetic abnormalities [i.e., t(4;14), t(14;16), and del(17p)] associated with multiple myeloma ...

Abstract	Multiple myeloma is the second most common hematological malignancy in the USA and Europe. Despite improvements in the 5-year and overall survival rates over the past decade, older adults (aged ≥65 years) with multiple myeloma continue to experience disproportionately worse outcomes than their younger counterparts. These differences in outcomes arise from the increased prevalence of vulnerabilities such as medical comorbidities and frailty seen with advancing age that can influence treatment-delivery and tolerance and impact survival. In general, geriatric assessments can help identify those patients more likely to benefit from enhanced toxicity risk-prediction and aid treatment decision-making. Despite the observed benefits of geriatric assessments and other screening frailty tools, provider and systems-level barriers continue to influence the overall perception of the feasibility of geriatric assessments in clinical practice settings. Clinical trials are underway evaluating the efficacy and safety of various multiple myeloma therapies in less fit/frail older adults, with a minority examining fitness-based/risk-adapted approaches. Thus, significant gaps exist in knowing which myeloma therapies are most appropriate for older and more vulnerable adults with multiple myeloma. The purpose of this Review is to discuss how geriatric assessments can be used to guide the management of transplant-ineligible patients; and to highlight frontline therapies for standard-risk and high-risk cytogenetic abnormalities [i.e., t(4;14), t(14;16), and del(17p)] associated with multiple myeloma. We also discuss the current shortcomings of the existing clinical approaches to care and highlight ongoing clinical trials evaluating newer fitness-based approaches to managing transplant-ineligible patients.
MeSH term(s)	Aged ; Europe ; Frail Elderly ; Frailty ; Geriatric Assessment ; Humans ; Multiple Myeloma/diagnosis ; Multiple Myeloma/therapy
Language	English
Publishing date	2020-12-17
Publishing country	Netherlands
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2556813-9
ISSN	1879-4076 ; 1879-4068
ISSN (online)	1879-4076
ISSN	1879-4068
DOI	10.1016/j.jgo.2020.12.001
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Genetic risk assessment after iodine-131 exposure: an opportunity and obligation for nuclear medicine.

Dottorini, M E

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

1996 Volume 37, Issue 4, Page(s) 612–615

MeSH term(s)	Abnormalities, Radiation-Induced/epidemiology ; Abortion, Spontaneous/epidemiology ; Female ; Humans ; Infant, Newborn ; Iodine Radioisotopes/adverse effects ; Iodine Radioisotopes/therapeutic use ; Neoplasms, Radiation-Induced/epidemiology ; Pregnancy ; Pregnancy Outcome/epidemiology ; Prenatal Exposure Delayed Effects ; Radiation Dosage ; Radionuclide Imaging ; Risk Factors ; Thyroid Neoplasms/diagnostic imaging ; Thyroid Neoplasms/radiotherapy
Chemical Substances	Iodine Radioisotopes
Language	English
Publishing date	1996-04
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	80272-4
ISSN	1535-5667 ; 0161-5505 ; 0097-9058 ; 0022-3123
ISSN (online)	1535-5667
ISSN	0161-5505 ; 0097-9058 ; 0022-3123
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 114: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 328: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Reciprocal Incremental Value of 18F-FDG-PET and Cerebrospinal Fluid Biomarkers in Mild Cognitive Impairment Patients Suspected for Alzheimer's Disease and Inconclusive First Biomarker.

Massa, Federico / Farotti, Lucia / Eusebi, Paolo / Capello, Elisabetta / Dottorini, Massimo E / Tranfaglia, Cristina / Bauckneht, Matteo / Morbelli, Silvia / Nobili, Flavio / Parnetti, Lucilla

Journal of Alzheimer's disease : JAD

2019 Volume 72, Issue 4, Page(s) 1193–1207

Abstract: Background: In Alzheimer's disease (AD) diagnosis, both cerebrospinal fluid (CSF) biomarkers and FDG-PET sometimes give inconclusive results.: Objective: To evaluate the incremental diagnostic value of FDG-PET over CSF biomarkers, and vice versa, in ... ...

Abstract	Background: In Alzheimer's disease (AD) diagnosis, both cerebrospinal fluid (CSF) biomarkers and FDG-PET sometimes give inconclusive results. Objective: To evaluate the incremental diagnostic value of FDG-PET over CSF biomarkers, and vice versa, in patients with mild cognitive impairment (MCI) and suspected AD, in which the first biomarker resulted inconclusive. Methods: A consecutive series of MCI patients was retrospectively selected from two Memory Clinics where, as per clinical routine, either the first biomarker choice is FDG-PET and CSF biomarkers are only used in patients with uninformative FDG-PET, or vice versa. We defined criteria of uncertainty in interpretation of FDG-PET and CSF biomarkers, according to current evidence. The final diagnosis was established according to clinical-neuropsychological follow-up of at least one year (mean 4.4±2.2). Results: When CSF was used as second biomarker after FDG-PET, 14 out of 36 (39%) received informative results. Among these 14 patients, 11 (79%) were correctly classified with respect to final diagnosis, thus with a relative incremental value of CSF over FDG-PET of 30.6%. When FDG-PET was used as second biomarker, 26 out of 39 (67%) received informative results. Among these 26 patients, 15 (58%) were correctly classified by FDG-PET with respect to final diagnosis, thus with a relative incremental value over CSF of 38.5%. Conclusion: Our real-world data confirm the added values of FDG-PET (or CSF) in a diagnostic pathway where CSF (or FDG-PET) was used as first biomarkers in suspected AD. These findings should be replicated in larger studies with prospective enrolment according to a Phase III design.
MeSH term(s)	Aged ; Alzheimer Disease/cerebrospinal fluid ; Alzheimer Disease/diagnosis ; Alzheimer Disease/diagnostic imaging ; Amyloid beta-Peptides/cerebrospinal fluid ; Biomarkers/cerebrospinal fluid ; Brain/diagnostic imaging ; Cognitive Dysfunction/cerebrospinal fluid ; Cognitive Dysfunction/diagnostic imaging ; Disease Progression ; Female ; Fluorodeoxyglucose F18 ; Humans ; Male ; Middle Aged ; Neuropsychological Tests ; Positron-Emission Tomography ; Retrospective Studies ; tau Proteins/cerebrospinal fluid
Chemical Substances	Amyloid beta-Peptides ; Biomarkers ; tau Proteins ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2019-11-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1440127-7
ISSN	1875-8908 ; 1387-2877
ISSN (online)	1875-8908
ISSN	1387-2877
DOI	10.3233/JAD-190539
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6084: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Semi-quantification and grading of amyloid PET: A project of the European Alzheimer's Disease Consortium (EADC).

Chincarini, A / Peira, E / Morbelli, S / Pardini, M / Bauckneht, M / Arbizu, J / Castelo-Branco, M / Büsing, K A / de Mendonça, A / Didic, M / Dottorini, M / Engelborghs, S / Ferrarese, C / Frisoni, G B / Garibotto, V / Guedj, E / Hausner, L / Hugon, J / Verhaeghe, J /

Mecocci, P / Musarra, M / Queneau, M / Riverol, M / Santana, I / Guerra, U P / Nobili, F

NeuroImage. Clinical

2019 Volume 23, Page(s) 101846

Abstract: Background: amyloid-PET reading has been classically implemented as a binary assessment, although the clinical experience has shown that the number of borderline cases is non negligible not only in epidemiological studies of asymptomatic subjects but ... ...

Abstract	Background: amyloid-PET reading has been classically implemented as a binary assessment, although the clinical experience has shown that the number of borderline cases is non negligible not only in epidemiological studies of asymptomatic subjects but also in naturalistic groups of symptomatic patients attending memory clinics. In this work we develop a model to compare and integrate visual reading with two independent semi-quantification methods in order to obtain a tracer-independent multi-parametric evaluation. Methods: We retrospectively enrolled three cohorts of cognitively impaired patients submitted to Conclusion: It is possible to construct a map between different tracers and different quantification methods without resorting to ad-hoc acquired cases. We used a 5-level visual scale which, together with a mathematical model, delivered cut-offs and transition regions on tracers that are (largely) independent from the population. All fluorinated tracers appeared to have the same contrast and discrimination ability with respect to the negative-to-positive grading. We validated the integration of both visual reading and different quantifiers in a more robust framework thus bridging the gap between a binary and a user-independent continuous scale.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/epidemiology ; Alzheimer Disease/metabolism ; Brain/diagnostic imaging ; Brain/metabolism ; Cohort Studies ; Europe/epidemiology ; Female ; Fluorine Radioisotopes/metabolism ; Humans ; Male ; Middle Aged ; Plaque, Amyloid/diagnostic imaging ; Plaque, Amyloid/metabolism ; Positron-Emission Tomography/methods ; Positron-Emission Tomography/trends ; Retrospective Studies
Chemical Substances	Fluorine Radioisotopes
Language	English
Publishing date	2019-05-04
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2701571-3
ISSN	2213-1582 ; 2213-1582
ISSN (online)	2213-1582
ISSN	2213-1582
DOI	10.1016/j.nicl.2019.101846
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: A Review of Clinical Practice Guidelines and Treatment Recommendations for Cancer Care in the COVID-19 Pandemic.

Zaniboni, Alberto / Ghidini, Michele / Grossi, Francesco / Indini, Alice / Trevisan, Francesca / Iaculli, Alessandro / Dottorini, Lorenzo / Moleri, Giovanna / Russo, Alessandro / Vavassori, Ivano / Brevi, Alessandra / Rausa, Emanuele / Boni, Luigi / Dondossola, Daniele / Valeri, Nicola / Ghidini, Antonio / Tomasello, Gianluca / Petrelli, Fausto

Cancers

2020 Volume 12, Issue 9

Abstract: The COVID-19 pandemic has inevitably caused those involved in cancer care to change clinical practice in order to minimize the risk of infection while maintaining cancer treatment as a priority. General advice during the pandemic suggests that most ... ...

Abstract	The COVID-19 pandemic has inevitably caused those involved in cancer care to change clinical practice in order to minimize the risk of infection while maintaining cancer treatment as a priority. General advice during the pandemic suggests that most patients continue with ongoing therapies or planned surgeries, while follow-up visits may instead be delayed until the resolution of the outbreak. We conducted a literature search using PubMed to identify articles published in English language that reported on care recommendations for cancer patients during the COVID-19 pandemic from its inception up to 1st June 2020, using the terms "(cancer or tumor) AND (COVID 19)". Articles were selected for relevance and split into five categories: (1) personal recommendations of single or multiple authors, (2) recommendations of single authoritative centers, (3) recommendations of panels of experts or of multiple regional comprehensive centers, (4) recommendations of multicenter cooperative groups, (5) official guidelines or recommendations of health authorities. Of the 97 included studies, 10 were personal recommendations of single or multiple independent authors, 16 were practice recommendations of single authoritative cancer centers, 35 were recommendations provided by panel of experts or of multiple regional comprehensive centers, 19 were cooperative group position papers, and finally, 17 were official guidelines statements. The COVID-19 pandemic is a global emergency, and has rapidly modified our clinical practice. Delaying unnecessary treatment, minimizing toxicity, and identifying care priorities for surgery, radiotherapy, and systemic therapies must be viewed as basic priorities in the COVID-19 era.
Keywords	covid19
Language	English
Publishing date	2020-08-29
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers12092452
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito