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  1. Book ; Online: Platons Patient

    Walker, Andreas

    ein Beitrag zur Archäologie des Arzt-Patienten-Verhältnisses

    (Schriftenreihe Medizin - Ethik - Recht ; 18)

    2010  

    Author's details Andreas Walker. Martin-Luther-Universität Halle-Wittenberg, Interdisziplinäres Zentrum Medizin-Ethik-Recht. Hrsg. von Hans Lilie
    Series title Schriftenreihe Medizin - Ethik - Recht ; 18
    Collection
    Subject code 610
    Language German
    Size 43 S.
    Publisher Martin-Luther-Universität Halle-Wittenberg, Interdisziplinäres Zentrum Medizin-Ethik-Recht
    Publishing place Halle (Saale)
    Publishing country Germany
    Document type Book ; Online
    HBZ-ID HT017125688
    ISBN 978-3-86829-235-0 ; 3-86829-235-7
    DOI 10.4126/38m-004406622
    Database Repository for Life Sciences

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  2. Article ; Online: Medical decision-making in hospices from the viewpoint of physicians: results from two qualitative studies.

    Walker, Andreas / Breitsameter, Christof

    BMC palliative care

    2022  Volume 21, Issue 1, Page(s) 158

    Abstract: Background: Physicians who practice in a hospice are responsible for working with patients and nursing staff to develop a medication plan, monitor symptoms and pain, and adjust medication if necessary. In inpatient hospices in Germany, physicians are ... ...

    Abstract Background: Physicians who practice in a hospice are responsible for working with patients and nursing staff to develop a medication plan, monitor symptoms and pain, and adjust medication if necessary. In inpatient hospices in Germany, physicians are part of a multi-professional approach, but not part of the hospice team itself. However, there is no, or hardly any, literature on medical practice in a hospice setting. Therefore, we wanted to know how physicians reflect upon their role in hospice within a multi-professional setting, how they communicate with patients, relatives, nursing staff and other physicians, and what the limitations of these communication processes are.
    Methods: By means of two qualitative studies we explored how physicians classify their activities as part of the hospice organization. The study design followed Grounded Theory procedures.
    Results: The physicians named an appropriate interpretation of the patient's wishes as the challenge of everyday practice which can lead to differences of perspective with those involved: with nursing staff, who would prefer an alternative form of medication, with relatives, who do not accept that the patient refuses nutrition, with other physicians, who have a different opinion about appropriate treatment. For physicians, this is all the more challenging as communication with the patient becomes increasingly uncertain due to the patient's illness. Again and again, medical measures have to be negotiated on several levels.
    Conclusion: Multi-professional organizations that have to deal with differences in perspective handle them by clearly distinguishing areas of responsibility, an aspect that physicians also claim for themselves. For physicians the question arises repeatedly whether they have correctly interpreted the wishes of the patient. They must continuously reassure themselves of the patient's wishes and this presents them with communication challenges not only with the patient, but also with the nursing staff and relatives and, more recently, with their colleagues.
    MeSH term(s) Clinical Decision-Making ; Hospice Care ; Hospices ; Humans ; Physicians ; Qualitative Research
    Language English
    Publishing date 2022-09-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091556-1
    ISSN 1472-684X ; 1472-684X
    ISSN (online) 1472-684X
    ISSN 1472-684X
    DOI 10.1186/s12904-022-00999-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Activity of amorolfine or ciclopirox in combination with terbinafine against pathogenic fungi in onychomycosis-Results of an in vitro investigation.

    Schaller, Martin / Walker, Birgit / Nabhani, Schafiq / Odon, Astrid / Riel, Simon / Jäckel, Andreas

    Mycoses

    2024  Volume 67, Issue 3, Page(s) e13710

    Abstract: Background: Onychomycoses are difficult-to-treat fungal infections with high relapse rates. Combining oral and topical antifungal drugs is associated with higher success rates. Additive or synergistic modes of action are expected to enhance treatment ... ...

    Abstract Background: Onychomycoses are difficult-to-treat fungal infections with high relapse rates. Combining oral and topical antifungal drugs is associated with higher success rates. Additive or synergistic modes of action are expected to enhance treatment success rates.
    Objectives: Investigation of the combined effects of antifungal drugs in vitro with different modes of action and application on clinical isolates from mycotic nails.
    Methods: Isolates of Trichophyton rubrum, Trichophyton interdigitale and Scopulariopsis brevicaulis were collected from infected toenail specimens of patients with onychomycosis. Susceptibility testing was performed in 96-well polystyrene plates using a standard stepwise microdilution protocol. Additive or synergistic activity at varying concentrations was investigated by the checkerboard method.
    Results: Combining terbinafine with amorolfine tended to be more effective than terbinafine in conjunction with ciclopirox. In most combinations, additive effects were observed. Synergy was detected in combinations with involving amorolfine in S. brevicaulis. These additive and synergistic interactions indicate that combined therapy with topical amorolfine and oral terbinafine is justified. Sublimation of amorolfine (and terbinafine) may enhance the penetration in and through the nail plate, and support treatment efficacy.
    Conclusions: These in vitro results support the notion that combining oral terbinafine and topical amorolfine is beneficial to patients with onychomycosis, particularly if the pathogen is a non-dermatophyte fungus such as S. brevicaulis.
    MeSH term(s) Humans ; Terbinafine/pharmacology ; Terbinafine/therapeutic use ; Onychomycosis/drug therapy ; Onychomycosis/microbiology ; Ciclopirox/pharmacology ; Ciclopirox/therapeutic use ; Antifungal Agents/therapeutic use ; Naphthalenes ; Morpholines
    Chemical Substances Terbinafine (G7RIW8S0XP) ; Ciclopirox (19W019ZDRJ) ; Antifungal Agents ; amorolfine (AB0BHP2FH0) ; Naphthalenes ; Morpholines
    Language English
    Publishing date 2024-02-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 392487-7
    ISSN 1439-0507 ; 0933-7407
    ISSN (online) 1439-0507
    ISSN 0933-7407
    DOI 10.1111/myc.13710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Neuroacanthocytosis Syndromes: The Clinical Perspective.

    Walker, Ruth H / Peikert, Kevin / Jung, Hans H / Hermann, Andreas / Danek, Adrian

    Contact (Thousand Oaks (Ventura County, Calif.))

    2023  Volume 6, Page(s) 25152564231210339

    Abstract: The two very rare neurodegenerative diseases historically known as the "neuroacanthocytosis syndromes" are due to mutations of ... ...

    Abstract The two very rare neurodegenerative diseases historically known as the "neuroacanthocytosis syndromes" are due to mutations of either
    Language English
    Publishing date 2023-12-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2964312-0
    ISSN 2515-2564 ; 2515-2564
    ISSN (online) 2515-2564
    ISSN 2515-2564
    DOI 10.1177/25152564231210339
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Zur Narrativierung des "guten" Sterbens

    Walker, Andreas

    Zeitschrift fuer Medizin-Ethik-Recht

    2017  Volume 8, Issue 1, Page(s) 89–100

    Title translation On narrativization of "good" dying
    Keywords attitudes to death ; death ; philosophy ; principle-based ethics ; morality ; terminal care ; palliative care ; hospices ; communication ; jesus christus ; socrates <philosophus> (v469 - v399)
    Subject code AN
    Language German
    Document type Article
    ZDB-ID 2671101-1
    ISSN 2194-377X ; 2194-3761
    ISSN (online) 2194-377X
    ISSN 2194-3761
    Database Ethics in Medicine (ETHMED)

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  6. Article ; Online: Exclusive Human Milk Diet for Extremely Premature Infants: A Novel Fortification Strategy That Enhances the Bioactive Properties of Fresh, Frozen, and Pasteurized Milk Specimens.

    Philip, Roy K / Romeih, Ehab / Bailie, Elizabeth / Daly, Mandy / McGourty, Kieran D / Grabrucker, Andreas M / Dunne, Colum P / Walker, Gavin

    Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine

    2023  Volume 18, Issue 4, Page(s) 279–290

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Infant, Newborn ; Infant ; Female ; Animals ; Cattle ; Humans ; Milk, Human/chemistry ; Infant, Extremely Premature ; Lactalbumin/analysis ; Lactoferrin/analysis ; Breast Feeding ; Diet
    Chemical Substances Lactalbumin (9013-90-5) ; Lactoferrin (EC 3.4.21.-)
    Language English
    Publishing date 2023-04-18
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 2234680-6
    ISSN 1556-8342 ; 1556-8253
    ISSN (online) 1556-8342
    ISSN 1556-8253
    DOI 10.1089/bfm.2022.0254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Neuroacanthocytosis Syndromes

    Ruth H. Walker / Kevin Peikert / Hans H. Jung / Andreas Hermann / Adrian Danek

    Contact, Vol

    The Clinical Perspective

    2023  Volume 6

    Abstract: The two very rare neurodegenerative diseases historically known as the “neuroacanthocytosis syndromes” are due to mutations of either VPS13A or XK. These are phenotypically similar disorders that affect primarily the basal ganglia and hence result in ... ...

    Abstract The two very rare neurodegenerative diseases historically known as the “neuroacanthocytosis syndromes” are due to mutations of either VPS13A or XK. These are phenotypically similar disorders that affect primarily the basal ganglia and hence result in involuntary abnormal movements as well as neuropsychiatric and cognitive alterations. There are other shared features such as abnormalities of red cell membranes which result in acanthocytes, whose relationship to neurodegeneration is not yet known. Recent insights into the functions of these two proteins suggest dysfunction of lipid processing and trafficking at the subcellular level and may provide a mechanism for neuronal dysfunction and death, and potentially a target for therapeutic interventions.
    Keywords Biology (General) ; QH301-705.5 ; Biochemistry ; QD415-436
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Bis(Iminophosphorano)-Substituted Pyridinium Ions and their Corresponding Bispyridinylidene Organic Electron Donors.

    Frenette, Brandon L / Arsenault, Nadine / Walker, Sarah L / Decken, Andreas / Dyker, C Adam

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2021  Volume 27, Issue 33, Page(s) 8528–8536

    Abstract: Optimized synthetic procedures for pyridinium ions featuring iminophosphorano (-N= ... ...

    Abstract Optimized synthetic procedures for pyridinium ions featuring iminophosphorano (-N=PR
    Language English
    Publishing date 2021-05-14
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202100318
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Early Mortality After Catheter Ablation of Atrial Fibrillation.

    Bollmann, Andreas / König, Sebastian / Basedow, Frederike / Hindricks, Gerhard / Walker, Jochen

    Journal of the American College of Cardiology

    2020  Volume 75, Issue 10, Page(s) 1243–1244

    MeSH term(s) Atrial Fibrillation/surgery ; Catheter Ablation ; Humans ; Stroke
    Language English
    Publishing date 2020-03-12
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2019.11.066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Differentielle Proteomanalyse in einem Modell der Epileptogenese

    Walker, Andreas Gerhard

    Regulation inflammations-assoziierter Proteine

    2016  

    Author's details von Andreas Gerhard Walker
    Language German
    Size 139 Seiten, Diagramme, Illustrationen
    Publisher Ludwig-Maximilians-Universität München
    Publishing place München
    Document type Book
    Database Special collection on veterinary medicine and general parasitology

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