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  1. Article ; Online: Healthcare Resource Utilization Following Single-lead Electrocardiogram Screening for Atrial Fibrillation in Older Individuals at Primary Care Visits.

    Atlas, Steven J / Borowsky, Leila H / Chang, Yuchiao / Ashburner, Jeffrey M / Ellinor, Patrick T / Lubitz, Steven A / Singer, Daniel E

    Journal of general internal medicine

    2024  

    Language English
    Publishing date 2024-04-02
    Publishing country United States
    Document type Letter
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-024-08733-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2205: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  2. Article ; Online: Ventricular arrhythmia management in patients with genetic cardiomyopathies.

    Sharif, Zain I / Lubitz, Steven A

    Heart rhythm O2

    2021  Volume 2, Issue 6Part B, Page(s) 819–831

    Abstract: Genetic cardiomyopathies are associated with increased risk for cardiac arrhythmias and sudden cardiac death. The management of ventricular arrhythmias (VAs) in patients with these conditions can be nuanced due to particular disease-based considerations, ...

    Abstract Genetic cardiomyopathies are associated with increased risk for cardiac arrhythmias and sudden cardiac death. The management of ventricular arrhythmias (VAs) in patients with these conditions can be nuanced due to particular disease-based considerations, yet data specifically addressing management in these patients are limited. Here we describe the current evidence-based approach to the management of ventricular rhythm disorders in patients with genetic forms of cardiomyopathy, namely, hypertrophic cardiomyopathy, arrhythmogenic cardiomyopathy, left ventricular noncompaction, and Brugada syndrome, including recommendations from consensus guideline statements when available.
    Language English
    Publishing date 2021-12-17
    Publishing country United States
    Document type Journal Article
    ISSN 2666-5018
    ISSN (online) 2666-5018
    DOI 10.1016/j.hroo.2021.10.009
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  3. Article ; Online: Clockwork and Arrhythmias in Catecholaminergic Polymorphic Ventricular Tachycardia.

    Lubitz, Steven A

    JACC. Clinical electrophysiology

    2017  Volume 3, Issue 11, Page(s) 1318–1320

    MeSH term(s) Arrhythmias, Cardiac ; Humans ; Tachycardia, Ventricular
    Language English
    Publishing date 2017-09-27
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2017.08.010
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  4. Article ; Online: Clinical and genetic evaluation after sudden cardiac arrest.

    Harris, Stephanie L / Lubitz, Steven A

    Journal of cardiovascular electrophysiology

    2020  Volume 31, Issue 2, Page(s) 570–578

    Abstract: Sudden cardiac arrest (SCA) and sudden cardiac death (SCD) can be attributed to cardiac, respiratory, metabolic, and toxicologic etiologies. Most cases of SCD are caused by coronary artery disease and approximately 40% of cardiac arrests are unexplained. ...

    Abstract Sudden cardiac arrest (SCA) and sudden cardiac death (SCD) can be attributed to cardiac, respiratory, metabolic, and toxicologic etiologies. Most cases of SCD are caused by coronary artery disease and approximately 40% of cardiac arrests are unexplained. Inherited arrythmias and cardiomyopathies are important contributors to SCA and SCD. Identifying an inherited condition after such an event not only has important ramifications for the individual, but also for relatives who may be at risk for the familial condition. This review will provide an overview of inherited cardiovascular disorders than can predispose to SCA/SCD, review the diagnostic evaluation for an individual and/or family after an SCA/SCD, and discuss the role of genetic testing.
    MeSH term(s) Arrhythmias, Cardiac/complications ; Arrhythmias, Cardiac/genetics ; Arrhythmias, Cardiac/physiopathology ; Arrhythmias, Cardiac/therapy ; Cardiomyopathies/complications ; Cardiomyopathies/genetics ; Cardiomyopathies/physiopathology ; Cardiomyopathies/therapy ; DNA Mutational Analysis ; Death, Sudden, Cardiac/etiology ; Death, Sudden, Cardiac/prevention & control ; Electrocardiography ; Female ; Genetic Predisposition to Disease ; Heredity ; Humans ; Male ; Middle Aged ; Mutation ; Pedigree ; Phenotype ; Predictive Value of Tests ; Prognosis ; Risk Assessment ; Risk Factors ; Young Adult
    Language English
    Publishing date 2020-01-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.14333
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    Zs.A 2863: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Article ; Online: Genetics, Exercise, and Early-Onset Arrhythmogenic Right Ventricular Cardiomyopathy.

    Lubitz, Steven A

    JACC. Clinical electrophysiology

    2015  Volume 1, Issue 6, Page(s) 561–562

    Language English
    Publishing date 2015-12
    Publishing country United States
    Document type Editorial
    ISSN 2405-5018
    ISSN (online) 2405-5018
    DOI 10.1016/j.jacep.2015.09.006
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  6. Article ; Online: Prevalence and Incidence of Atrial Fibrillation Among Older Primary Care Patients.

    Khurshid, Shaan / Ashburner, Jeffrey M / Ellinor, Patrick T / McManus, David D / Atlas, Steven J / Singer, Daniel E / Lubitz, Steven A

    JAMA network open

    2023  Volume 6, Issue 2, Page(s) e2255838

    MeSH term(s) Humans ; Atrial Fibrillation/epidemiology ; Incidence ; Prevalence ; Risk Factors ; Primary Health Care
    Language English
    Publishing date 2023-02-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2022.55838
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  7. Article ; Online: ECG monitoring after acute ischemic stroke: Does patient selection matter?

    Katan, Mira / Lubitz, Steven A

    Neurology

    2018  Volume 92, Issue 2, Page(s) 65–66

    MeSH term(s) Atrial Fibrillation ; Brain Ischemia ; Electrocardiography ; Humans ; Patient Selection ; Stroke
    Language English
    Publishing date 2018-12-07
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000006719
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    Ui II Zs.153: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 18: Show issues
    Zs.MO 374: Show issues

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  8. Article ; Online: Point-of-care screening for atrial fibrillation: Where are we, and where do we go next?

    Ashburner, Jeffrey M / Khurshid, Shaan / Atlas, Steven J / Singer, Daniel E / Lubitz, Steven A

    Cardiovascular digital health journal

    2021  Volume 2, Issue 6, Page(s) 294–297

    Language English
    Publishing date 2021-10-08
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6936
    ISSN (online) 2666-6936
    DOI 10.1016/j.cvdhj.2021.10.001
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  9. Article ; Online: Cross-modal autoencoder framework learns holistic representations of cardiovascular state.

    Radhakrishnan, Adityanarayanan / Friedman, Sam F / Khurshid, Shaan / Ng, Kenney / Batra, Puneet / Lubitz, Steven A / Philippakis, Anthony A / Uhler, Caroline

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 2436

    Abstract: A fundamental challenge in diagnostics is integrating multiple modalities to develop a joint characterization of physiological state. Using the heart as a model system, we develop a cross-modal autoencoder framework for integrating distinct data ... ...

    Abstract A fundamental challenge in diagnostics is integrating multiple modalities to develop a joint characterization of physiological state. Using the heart as a model system, we develop a cross-modal autoencoder framework for integrating distinct data modalities and constructing a holistic representation of cardiovascular state. In particular, we use our framework to construct such cross-modal representations from cardiac magnetic resonance images (MRIs), containing structural information, and electrocardiograms (ECGs), containing myoelectric information. We leverage the learned cross-modal representation to (1) improve phenotype prediction from a single, accessible phenotype such as ECGs; (2) enable imputation of hard-to-acquire cardiac MRIs from easy-to-acquire ECGs; and (3) develop a framework for performing genome-wide association studies in an unsupervised manner. Our results systematically integrate distinct diagnostic modalities into a common representation that better characterizes physiologic state.
    MeSH term(s) Genome-Wide Association Study ; Heart/diagnostic imaging ; Cardiovascular System/diagnostic imaging ; Electrocardiography ; Learning
    Language English
    Publishing date 2023-04-28
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-38125-0
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  10. Article ; Online: Adjusting for common variant polygenic scores improves yield in rare variant association analyses.

    Jurgens, Sean J / Pirruccello, James P / Choi, Seung Hoan / Morrill, Valerie N / Chaffin, Mark / Lubitz, Steven A / Lunetta, Kathryn L / Ellinor, Patrick T

    Nature genetics

    2023  Volume 55, Issue 4, Page(s) 544–548

    Abstract: With the emergence of large-scale sequencing data, methods for improving power in rare variant association tests are needed. Here we show that adjusting for common variant polygenic scores improves yield in gene-based rare variant association tests ... ...

    Abstract With the emergence of large-scale sequencing data, methods for improving power in rare variant association tests are needed. Here we show that adjusting for common variant polygenic scores improves yield in gene-based rare variant association tests across 65 quantitative traits in the UK Biobank (up to 20% increase at α = 2.6 × 10
    MeSH term(s) Multifactorial Inheritance/genetics ; Phenotype ; Quantitative Trait Loci ; Polymorphism, Single Nucleotide/genetics ; Models, Genetic ; Genome-Wide Association Study
    Language English
    Publishing date 2023-03-23
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1108734-1
    ISSN 1546-1718 ; 1061-4036
    ISSN (online) 1546-1718
    ISSN 1061-4036
    DOI 10.1038/s41588-023-01342-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3613: Show issues Location:
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    Zs.MG 46: Show issues

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