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  1. Article ; Online: Study on the outdoor thermal comfort of college students under different activity intensities in a high-altitude climate zone.

    Zhang, Yingzi / Zhang, Xiaobo / Han, Jiaqin / Liu, Xinxing

    Frontiers in public health

    2024  Volume 12, Page(s) 1365470

    Abstract: Introduction: Research on the outdoor thermal comfort (OTC) of a university campus is beneficial to the physical and mental health of college students.: Methods: In this study, the OTC of students attending Tibet University in Lhasa, which ... ...

    Abstract Introduction: Research on the outdoor thermal comfort (OTC) of a university campus is beneficial to the physical and mental health of college students.
    Methods: In this study, the OTC of students attending Tibet University in Lhasa, which experiences high-altitude cold climate conditions, under different activity intensities was studied using field measurements and a questionnaire survey.
    Results: With the increase in activity intensity, the comfort physiologically equivalent temperature (PET) value gradually increased in summer, while the comfortable PET value gradually decreased in winter. The most comfortable PET value is 17.6°C in summer and 11.5°C in winter. The neutral PET of Tibetan college students during outdoor activities in summer was 16.3°C, and the neutral PET of outdoor activities in winter was 12.1°C. Gender and ethnicity had different effects on thermal sensation under different activity intensities. Under vigorous-intensity activities, PET in winter and summer had the greatest influence on thermal sensation. The situation was different under moderate-intensity activity. PET had the greatest influence on thermal sensation in summer, and Tmrt had the greatest influence on thermal sensation in winter.
    Discussion: These findings provide a basis for an improved design of the outdoor environment under different outdoor activity intensities in high-altitude areas.
    MeSH term(s) Humans ; Altitude ; Climate ; Seasons ; Temperature ; Surveys and Questionnaires
    Language English
    Publishing date 2024-03-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2024.1365470
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 3 Expression and Its Correlation with Prognosis and Growth of Serous Ovarian Cancer: Correlation of DYRK3 with Ovarian Cancer Survival.

    Sun, Jia / Zhang, Yingzi / Li, Aijie / Yu, Hao

    International journal of genomics

    2024  Volume 2024, Page(s) 6683202

    Abstract: Background: Epithelial ovarian cancer, primarily serous ovarian cancer (SOC), stands as a predominant cause of cancer-related mortality among women globally, emphasizing the urgent need for comprehensive research into its molecular underpinnings. Within ...

    Abstract Background: Epithelial ovarian cancer, primarily serous ovarian cancer (SOC), stands as a predominant cause of cancer-related mortality among women globally, emphasizing the urgent need for comprehensive research into its molecular underpinnings. Within this context, the dual-specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3) has emerged as a potential key player with implications for prognosis and tumor progression.
    Methods: This study conducted a meticulous retrospective analysis of 254 SOC cases from our medical center to unravel the prognostic significance of DYRK3. Survival analyses underscored DYRK3 as an independent adverse prognostic factor in SOC, with a hazard ratio of 2.60 (95% CI 1.67-4.07,
    Results: Our findings collectively illuminate DYRK3 as a pivotal tumor-promoting oncogene in SOC. Beyond its adverse prognostic implications, DYRK3 knockdown exhibited promising therapeutic potential by impeding cancer progression and potentially influencing the tumor immune microenvironment.
    Conclusions: This study establishes a compelling foundation for further research into DYRK3's intricate role and therapeutic potential in ovarian cancer treatment. As we unravel the complexities surrounding DYRK3, our work not only contributes to the understanding of SOC pathogenesis but also unveils new prospects for targeted therapeutic interventions, holding promise for improved outcomes in ovarian cancer management.
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2711883-6
    ISSN 2314-4378 ; 2314-436X
    ISSN (online) 2314-4378
    ISSN 2314-436X
    DOI 10.1155/2024/6683202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Spatiotemporal patterns and drivers of the urban air pollution island effect for 2273 cities in China.

    Niu, Lu / Zhang, Zhengfeng / Liang, Yingzi / van Vliet, Jasper

    Environment international

    2024  Volume 184, Page(s) 108455

    Abstract: Air pollution levels tend to be higher in urban areas than in surrounding rural areas, and this air pollution has a negative effect on human health. However, the spatiotemporal patterns of urban-rural air pollution differences and the determinants of ... ...

    Abstract Air pollution levels tend to be higher in urban areas than in surrounding rural areas, and this air pollution has a negative effect on human health. However, the spatiotemporal patterns of urban-rural air pollution differences and the determinants of these differences remain unclear. Here, we calculate the Urban Air Pollution Island (UAPI) intensity for PM
    MeSH term(s) Humans ; Cities ; Air Pollutants/analysis ; Particulate Matter/analysis ; Air Pollution/analysis ; China ; Environmental Monitoring/methods
    Chemical Substances Air Pollutants ; Particulate Matter
    Language English
    Publishing date 2024-01-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 554791-x
    ISSN 1873-6750 ; 0160-4120
    ISSN (online) 1873-6750
    ISSN 0160-4120
    DOI 10.1016/j.envint.2024.108455
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3131: Show issues Location:
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  4. Article ; Online: Spectroscopic studies of the role of dissolved organic matter in acenaphthene photodegradation in liquid water and ice.

    Xue, Shuang / Jiang, Caihong / Lin, Yingzi / Zhang, Zhaohong / Liu, Jiyang

    Environmental pollution (Barking, Essex : 1987)

    2024  Volume 347, Page(s) 123805

    Abstract: The effect of concentration and origin of dissolved organic matter (DOM) on acenaphthene (Ace) photodegradation in liquid water and ice was investigated, and the components in DOM which were involved in Ace photodegradation were identified. The DOM ... ...

    Abstract The effect of concentration and origin of dissolved organic matter (DOM) on acenaphthene (Ace) photodegradation in liquid water and ice was investigated, and the components in DOM which were involved in Ace photodegradation were identified. The DOM samples included Suwannee River fulvic acid (SRFA), Elliott soil humic acid (ESHA), and an effluent organic matter (EfOM) sample. Due to the production of hydroxyl radical (
    MeSH term(s) Water ; Photolysis ; Ice/analysis ; Dissolved Organic Matter ; Acenaphthenes ; Soil ; Humic Substances/analysis ; Water Pollutants, Chemical/chemistry
    Chemical Substances Water (059QF0KO0R) ; Ice ; Dissolved Organic Matter ; acenaphthene (V8UT1GAC5Y) ; Acenaphthenes ; Soil ; Humic Substances ; Water Pollutants, Chemical
    Language English
    Publishing date 2024-03-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2024.123805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2599: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article ; Online: CoGT

    Yingzi Bu / Ruoxi Gao / Bohan Zhang / Luchen Zhang / Duxin Sun

    ACS Omega, Vol 8, Iss 14, Pp 13232-

    Ensemble Machine Learning Method and Its Application on JAK Inhibitor Discovery

    2023  Volume 13242

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Probiotics treatment ameliorated mycophenolic acid-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis in mice.

    Zhang, Pengpeng / Chen, Jinwen / Ming, Yingzi / Niu, Ying

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1153188

    Abstract: Background: Mycophenolic acid (MPA)-induced colitis was still a severe side effect and challenge faced by solid transplant recipients. We aimed to explore the function and mechanism of probiotics in the treatment of MPA-induced colitis.: Methods: In ... ...

    Abstract Background: Mycophenolic acid (MPA)-induced colitis was still a severe side effect and challenge faced by solid transplant recipients. We aimed to explore the function and mechanism of probiotics in the treatment of MPA-induced colitis.
    Methods: In this study, 15 mice (C57BL/6) were randomly assigned into three groups: control (CNTL) group (
    Results: Compared with the CNTL group, the mice in MPA group showed a significantly decreased body weight, increased stool scores, shortened colon length and severe colon inflammation. However, probiotics treated MPA mice reversed the disease severity, indicating that probiotics ameliorated MPA-induced colitis in mice. Mechanistically, probiotics improved the intestinal barrier function by up-regulating the expression of sIgA, ZO-1 and Occludin. Moreover, MPA-induced colitis led to intestinal microbiota dysbiosis, including the change of
    Conclusion: Probiotics treatment ameliorated MPA-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis.
    Language English
    Publishing date 2023-07-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1153188
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  7. Article: Effect of mycophenolate mofetil alleviates carbon tetrachloride-induced liver fibrosis in mice.

    Ding, Peng / Zhang, Pengpeng / Li, Hao / Ming, Yingzi

    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences

    2023  Volume 48, Issue 6, Page(s) 821–828

    Abstract: Objectives: Hepatic fibrosis is a serious pathological consequence of chronic liver disease. Mycophenolate mofetil (MMF) is a commonly used immunosuppressant after organ transplant. However, the relationship between MMF and hepatic fibrosis remains ... ...

    Title translation 吗替麦考酚酯减轻四氯化碳诱导的小鼠肝纤维化.
    Abstract Objectives: Hepatic fibrosis is a serious pathological consequence of chronic liver disease. Mycophenolate mofetil (MMF) is a commonly used immunosuppressant after organ transplant. However, the relationship between MMF and hepatic fibrosis remains unclear. This study aims to explore the effect of MMF on hepatic fibrosis in mice and the potential mechanism.
    Methods: A total of 24 mice (male, 8-week old, C57BL/6) were randomly divided into a control group, a MMF group, a carbon tetrachloride (CCl
    Results: Compared with the CCl
    Conclusions: MMF could reduce CCl
    MeSH term(s) Male ; Animals ; Mice ; Mice, Inbred C57BL ; Mycophenolic Acid/therapeutic use ; Carbon Tetrachloride/toxicity ; Transforming Growth Factor beta1/genetics ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/drug therapy ; RNA, Messenger
    Chemical Substances Mycophenolic Acid (HU9DX48N0T) ; Carbon Tetrachloride (CL2T97X0V0) ; Transforming Growth Factor beta1 ; RNA, Messenger
    Language Chinese
    Publishing date 2023-08-07
    Publishing country China
    Document type Journal Article
    ZDB-ID 2168533-2
    ISSN 1672-7347
    ISSN 1672-7347
    DOI 10.11817/j.issn.1672-7347.2023.220542
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2681: Show issues Location:
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  8. Article ; Online: Clinical characteristics of patients with COVID-19 in Huangshi, China.

    Zhang, Xiwen / Xie, Jianfeng / Lu, Xiang / Ha, Weichao / Huang, Yingzi

    Journal of intensive medicine

    2022  Volume 2, Issue 3, Page(s) 195–196

    Language English
    Publishing date 2022-06-13
    Publishing country China
    Document type Journal Article
    ISSN 2667-100X
    ISSN (online) 2667-100X
    DOI 10.1016/j.jointm.2022.05.002
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  9. Article ; Online: Family functioning in the context of an adult family member with illness: A concept analysis.

    Zhang, Yingzi

    Journal of clinical nursing

    2018  Volume 27, Issue 15-16, Page(s) 3205–3224

    Abstract: Aim: To describe and explain how the concept of family functioning has been used in the targeted sample of health literature on adult family members with illness.: Background: Understanding the influence of illness on family functioning is central to ...

    Abstract Aim: To describe and explain how the concept of family functioning has been used in the targeted sample of health literature on adult family members with illness.
    Background: Understanding the influence of illness on family functioning is central to the provision of patient- and family-centred care. There is lack of consistency in utilising family functioning which creates confusion about the concept and can interfere with theory development in nursing science. A clear conceptual definition of attributes of family functioning based on concept analysis could act as a guide in the development of instruments to assess family functioning, the design of family-based interventions and their application in clinical practice.
    Design: Concept analysis.
    Data sources: Academic Search Premier, ProQuest Research Library, Family & Society Studies Worldwide, PsycINFO, SocINDEX, PubMed and CINAHL databases were searched within the last 20 years (1997-Dec. 2016) using the terms "family function*" and "patient." Studies of paediatric patients and non-English articles were excluded.
    Method: Rodgers' evolutionary perspective.
    Results: The findings suggest that family functioning in the context of illness is defined as family members' ability to maintain cohesive relationships with one another, fulfil family roles, cope with family problems, adjust to new family routines and procedures and effectively communicate with each other.
    Conclusion: Further research is needed to inform nurses' practice when assessing families or providing patient- and family-centred interventions to support family functioning across different sociocultural and political contexts, and further identification and evaluation of antecedents and consequences regarding family functioning from a nursing perspective.
    Relevance to clinical practice: Having a comprehensive understanding of the attributes, antecedents and consequences of ineffective family functioning can facilitate healthcare providers' ability to identify strengths and potential targets to improve family functioning among their clients.
    MeSH term(s) Adaptation, Psychological ; Adult ; Attitude to Health ; Chronic Disease/psychology ; Chronic Disease/therapy ; Family/psychology ; Family Relations/psychology ; Humans
    Language English
    Publishing date 2018-05-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1159483-4
    ISSN 1365-2702 ; 0962-1067 ; 1752-9816
    ISSN (online) 1365-2702
    ISSN 0962-1067 ; 1752-9816
    DOI 10.1111/jocn.14500
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3764: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article: Plant-microorganism-soil interaction under long-term low-dose ionizing radiation.

    Zeng, Guoqiang / Wen, Yingzi / Luo, Chuyang / Zhang, Yihong / Li, Fei / Xiong, Chao

    Frontiers in microbiology

    2024  Volume 14, Page(s) 1331477

    Abstract: As the environmental nuclear radiation pollution caused by nuclear-contaminated water discharge and other factors intensifies, more plant-microorganism-soil systems will be under long-term low-dose ionizing radiation (LLR). However, the regulatory ... ...

    Abstract As the environmental nuclear radiation pollution caused by nuclear-contaminated water discharge and other factors intensifies, more plant-microorganism-soil systems will be under long-term low-dose ionizing radiation (LLR). However, the regulatory mechanisms of the plant-microorganism-soil system under LLR are still unclear. In this study, we study a system that has been stably exposed to low-dose ionizing radiation for 10 years and investigate the response of the plant-microorganism-soil system to LLR based on the decay of the absorbed dose rate with distance. The results show that LLR affects the carbon and nitrogen migration process between plant-microorganism-soil through the "symbiotic microbial effect." The increase in the intensity of ionizing radiation led to a significant increase in the relative abundance of symbiotic fungi, such as Ectomycorrhizal fungi and Rhizobiales, which is accompanied by a significant increase in soil lignin peroxidase (LiP) activity, the C/N ratio, and C%. Meanwhile, enhanced radiation intensity causes adaptive changes in the plant functional traits. This study demonstrates that the "symbiotic microbial effect" of plant-microorganism-soil systems is an important process in terrestrial ecosystems in response to LLR.
    Language English
    Publishing date 2024-01-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1331477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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