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Article ; Online: Identification rate of

Ito, Akihiro / Ishida, Tadashi / Tachibana, Hiromasa / Nakanishi, Yosuke / Kawataki, Masanori / Yamazaki, Akio / Washio, Yasuyoshi

Journal of clinical microbiology

2024 Volume 62, Issue 4, Page(s) e0166523

Abstract: ... ...

Abstract	Many
MeSH term(s)	Humans ; Legionella ; Sputum ; Legionnaires' Disease/diagnosis ; Legionella pneumophila ; Pneumonia
Language	English
Publishing date	2024-03-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	390499-4
ISSN	1098-660X ; 0095-1137
ISSN (online)	1098-660X
ISSN	0095-1137
DOI	10.1128/jcm.01665-23
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Article ; Online: First Measurements on Triple Oxygen Isotopes of Dissolved Inorganic Phosphate in the Hydrosphere.

Sambuichi, Takashi / Tsunogai, Urumu / Ito, Masanori / Nakagawa, Fumiko

Environmental science & technology

2023 Volume 57, Issue 8, Page(s) 3415–3424

Abstract: Although dissolved inorganic phosphate (DIP) is an important nutrient in the hydrosphere, it is difficult to quantitatively clarify the dynamics of DIP in the hydrosphere using the ... ...

Abstract	Although dissolved inorganic phosphate (DIP) is an important nutrient in the hydrosphere, it is difficult to quantitatively clarify the dynamics of DIP in the hydrosphere using the δ
MeSH term(s)	Oxygen Isotopes/chemistry ; Phosphates/chemistry ; Fertilizers
Chemical Substances	Oxygen Isotopes ; Phosphates ; Fertilizers
Language	English
Publishing date	2023-02-14
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1520-5851
ISSN (online)	1520-5851
DOI	10.1021/acs.est.2c08520
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Observation of Histone H2AX Phosphorylation by Radiation-Induced Bystander Response Using Titanium Characteristic X-ray Microbeam.

Tomita, Masanori / Torigata, Masaya / Ohchi, Tadayuki / Ito, Atsushi

Biology

2023 Volume 12, Issue 5

Abstract: Radiation-induced bystander response (RIBR) is a response induced in non-irradiated cells that receive bystander signals from directly irradiated cells. X-ray microbeams are useful tools for elucidating the mechanisms underlying RIBR. However, previous X- ...

Abstract	Radiation-induced bystander response (RIBR) is a response induced in non-irradiated cells that receive bystander signals from directly irradiated cells. X-ray microbeams are useful tools for elucidating the mechanisms underlying RIBR. However, previous X-ray microbeams used low-energy soft X-rays with higher biological effects, such as aluminum characteristic X-rays, and the difference from conventional X-rays and γ-rays has often been discussed. The microbeam X-ray cell irradiation system at the Central Research Institute of Electric Power Industry has been upgraded to generate higher energy titanium characteristic X-rays (Ti
Language	English
Publishing date	2023-05-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2661517-4
ISSN	2079-7737
ISSN	2079-7737
DOI	10.3390/biology12050734
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Article ; Online: Nano-displacement sensing by phase-diversity optical digital coherent detection utilizing alternating quadrature phase-modulated reference light.

Wang, Xiaoyan / Kondo, Mitsuki / Ito, Ayumi / Hanawa, Masanori

Optics letters

2023 Volume 48, Issue 24, Page(s) 6512–6515

Abstract: We have introduced a nanometer-scale non-contact displacement sensing method that relies on phase-diversity optical digital coherent detection. In our prior work, we used a conventional setup involving a 90°optical hybrid, two balanced amplified ... ...

Abstract	We have introduced a nanometer-scale non-contact displacement sensing method that relies on phase-diversity optical digital coherent detection. In our prior work, we used a conventional setup involving a 90°optical hybrid, two balanced amplified photodetectors (BAPs), and a narrow-linewidth (NLW) laser, which is complex and costly. However, in this paper, we have streamlined the system configuration by employing alternating quadrature phase modulation (AQPM) reference light, implemented using a phase modulator and a BAP. Moreover, we've employed an economical distributed feedback (DFB) laser, enabling us to achieve displacement sensing at 1.6 nm with a resolution of 0.6 nm. It is notable that there is some degradation in the performance due to the phase noise compared to the NLW laser, which achieves a displacement sensing down to 0.6 nm with a 0.2 nm resolution. Nevertheless, the DFB-AQPM system holds a significant potential for cost-effective, high-resolution nanometer-scale sensing applications.
Language	English
Publishing date	2023-12-15
Publishing country	United States
Document type	Journal Article
ISSN	1539-4794
ISSN (online)	1539-4794
DOI	10.1364/OL.509587
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Article ; Online: A path integral molecular dynamics study on the muoniated xanthene-thione molecule.

Kuwahata, Kazuaki / Ito, Shigekazu / Tachikawa, Masanori

The Journal of chemical physics

2023 Volume 159, Issue 10

Abstract: A positive Mu is a useful tool for investigating the spin density of radical species. The theoretical estimation of its behavior in a molecule requires the inclusion of a quantum effect due to the small mass of muonium. Herein, we performed ab initio a ... ...

Abstract	A positive Mu is a useful tool for investigating the spin density of radical species. The theoretical estimation of its behavior in a molecule requires the inclusion of a quantum effect due to the small mass of muonium. Herein, we performed ab initio a path integral molecular dynamics (PIMD) simulation, which accurately included a multi-dimensional quantum effect, for muoniated 9H-xanthene-9-thione (μXT). Our results showed that the quantum effect significantly increased the hyperfine coupling constant (HFCC) value of μXT, which qualitatively improved the calculated HFCC value, compared to the experimental one. In the PIMD simulation, the bond length between muonium and sulfur in μXT is longer than that between hydrogen and sulfur in a hydrogenated 9H-xanthene-9-thione (HXT), leading to a spin density transfer from XT (9H-xanthene-9-thione) to muonium due to neutral dissociations. Additionally, we found that the S-Mu bond in μXT prefers a structure perpendicular to the molecular plane, where the interaction between Mu and the singly occupied molecular orbital of μXT is the strongest. These structural changes resulted in a larger HFCC value in the PIMD simulation of μXT.
Language	English
Publishing date	2023-09-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	3113-6
ISSN	1089-7690 ; 0021-9606
ISSN (online)	1089-7690
ISSN	0021-9606
DOI	10.1063/5.0159207
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Article ; Online: In situ hybridization analysis of olfactory receptor expression in the sea turtle olfactory organ.

Nakamuta, Shoko / Mori, Masanori / Ito, Miho / Kurita, Masanori / Miyazaki, Masao / Yamamoto, Yoshio / Nakamuta, Nobuaki

Cell and tissue research

2023 Volume 393, Issue 2, Page(s) 253–264

Abstract: The olfactory organ of turtles consists of an upper chamber epithelium (UCE) with associated glands, and a lower chamber epithelium (LCE) devoid of glands. The UCE and LCE are referred to as the air-nose and the water-nose, respectively, because the UCE ... ...

Abstract	The olfactory organ of turtles consists of an upper chamber epithelium (UCE) with associated glands, and a lower chamber epithelium (LCE) devoid of glands. The UCE and LCE are referred to as the air-nose and the water-nose, respectively, because the UCE is thought to detect airborne odorants, while the LCE detects waterborne odorants. However, it is not clear how the two are used in the olfactory organ. Odorant receptors (ORs) are the major olfactory receptors in turtles; they are classified as class I and II ORs, distinguished by their primary structure. Class I ORs are suggested to be receptive to water-soluble ligands and class II ORs to volatile ligands. This study analyzed the expression of class I and II ORs in hatchlings of the green sea turtle, Chelonia mydas, through in situ hybridization, to determine the localization of OR-expressing cells in the olfactory organ. Class I OR-expressing cells were distributed mainly in the LCE, implying that the LCE is receptive to waterborne odorants. Class II OR-expressing cells were distributed in both the UCE and LCE, implying that the entire olfactory organ is receptive to airborne odorants. The widespread expression of class II ORs may increase opportunities for sea turtles to sense airborne odorants.
MeSH term(s)	Animals ; Receptors, Odorant/genetics ; Receptors, Odorant/metabolism ; Turtles ; Ligands ; Olfactory Receptor Neurons/metabolism ; Smell ; Water ; Olfactory Mucosa/metabolism
Chemical Substances	Receptors, Odorant ; Ligands ; Water (059QF0KO0R)
Language	English
Publishing date	2023-06-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	125067-x
ISSN	1432-0878 ; 0302-766X
ISSN (online)	1432-0878
ISSN	0302-766X
DOI	10.1007/s00441-023-03782-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Author Correction: Induction of functional tissue-engineered skeletal muscle constructs by defined electrical stimulation.

Ito, Akira / Yamamoto, Yasunori / Sato, Masanori / Ikeda, Kazushi / Yamamoto, Masahiro / Fujita, Hideaki / Nagamori, Eiji / Kawabe, Yoshinori / Kamihira, Masamichi

Scientific reports

2024 Volume 14, Issue 1, Page(s) 7409

Language	English
Publishing date	2024-03-28
Publishing country	England
Document type	Published Erratum
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-57466-4
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Article ; Online: Factors Involved in Higher Knee Extension Torque Induced by Repetitive Peripheral Magnetic Stimulation.

Kamiue, Masanori / Ito, Tomotaka / Tsubahara, Akio / Kishimoto, Tomoya

American journal of physical medicine & rehabilitation

2023 Volume 103, Issue 1, Page(s) 24–30

Abstract: Objective: The study aimed to determine the relationship between knee extension torque induced by repetitive peripheral magnetic stimulation and the characteristics of the participants.: Design: This was a basic study with noninvasive intervention. ... ...

Abstract	Objective: The study aimed to determine the relationship between knee extension torque induced by repetitive peripheral magnetic stimulation and the characteristics of the participants. Design: This was a basic study with noninvasive intervention. Knee extension torque induced by repetitive peripheral magnetic stimulation (repetitive peripheral magnetic stimulation-induced torque) and maximum voluntary contraction were measured. Stepwise method of multiple regression was performed to determine the factors affecting repetitive peripheral magnetic stimulation-induced torque at 100% intensity and repetitive peripheral magnetic stimulation-induced torque divided by maximum voluntary contraction (percent maximum voluntary contraction). Subcutaneous fat thickness, vastus lateralis muscle thickness measured by ultrasound, maximum voluntary contraction, and mean power frequency of electromyography during maximum voluntary contraction were selected as independent variables. Results: Repetitive peripheral magnetic stimulation was applied to the right vastus lateralis of 30 young healthy adults (average age, 21.1 ± 0.3 yrs). In the multiple regression analysis, repetitive peripheral magnetic stimulation-induced torque ( P < 0.001) was shown to be independently and significantly associated with maximum voluntary contraction (β = 0.510), subcutaneous fat thickness (β = -0.358), and vastus lateralis muscle thickness (β = 0.208), while percent maximum voluntary contraction value ( P < 0.05) was independently and significantly associated with vastus lateralis muscle thickness (β = 1.059). Conclusions: Repetitive peripheral magnetic stimulation-induced torque decreases with thicker subcutaneous fat and increases with stronger maximum voluntary contraction or with thicker muscle.
MeSH term(s)	Adult ; Humans ; Young Adult ; Torque ; Isometric Contraction/physiology ; Knee ; Knee Joint/physiology ; Electromyography/methods ; Quadriceps Muscle/physiology ; Magnetic Phenomena ; Muscle, Skeletal/physiology ; Muscle Contraction/physiology
Language	English
Publishing date	2023-08-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	219390-5
ISSN	1537-7385 ; 0002-9491 ; 0894-9115
ISSN (online)	1537-7385
ISSN	0002-9491 ; 0894-9115
DOI	10.1097/PHM.0000000000002299
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Article ; Online: Gender difference of geographic distribution of physicians in Japan: three-point analysis of 1994, 2004 and 2014.

Kimura, Kazuki / Inoue, Kazuo / Ando, Takahito / Ito, Masanori

BMC health services research

2023 Volume 23, Issue 1, Page(s) 1404

Abstract: Background: Japan's medical education system produces 9,000 graduates annually. Despite the government's implementation of several strategies, including increasing the number of doctors trained, the country still struggles with a shortage of physicians ... ...

Abstract	Background: Japan's medical education system produces 9,000 graduates annually. Despite the government's implementation of several strategies, including increasing the number of doctors trained, the country still struggles with a shortage of physicians in rural areas. This study examined this issue, focusing on gender and considering years of physician experience, demographic and geographic factors. Methods: We analyzed the Physician Census from 1994, 2004, and 2014, examining data on physicians' gender and the number of years since licensure. To correct the impact of municipal mergers, the analysis was aligned with the number of municipalities in 2014 (1741). We examined data from each physician (gender and years of medical experience) and analyzed the demographic and geographic distribution trend using Spearman correlation coefficients. We then used the Gini coefficient to evaluate the distribution change of physicians based on gender and years of experience. Results: The number of physicians increased 1.29-fold over the 20-year observation period (1.23-fold for male physicians and 2.17-fold for female physicians), and the percentage of female physicians increased from 13.4% to 20.4%. We found that 87.7% of physicians were concentrated in the top 1/3 municipalities in terms of population. The number of female physicians was higher at 91.8% compared to 86.8% for male physicians. The Gini coefficients were lower for veteran physicians of both sexes than for younger physicians. The Gini coefficient for all physicians was 0.315-0.298-0.298 (male physicians: 0.311-0.289-0.283, female physicians: 0.394-0.385-0.395) The Gini coefficients for female compared to male physicians were higher in all age groups, showing that The distribution of female physicians is skewed toward urban areas. Conclusion: Female physicians are less distributed in rural areas than male physicians. In addition, despite the fact that the number of female physicians has increased more than male physicians over the past 20 years, the geographic ubiquity of female physicians has not improved. Since the trend of increasing the number of female physicians is expected to continue in the future, it is necessary to take some measures, such as providing a work-life balance suitable for female physicians.
MeSH term(s)	Humans ; Male ; Female ; Japan/epidemiology ; Sex Factors ; Physicians ; Physicians, Women ; Education, Medical
Language	English
Publishing date	2023-12-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2050434-2
ISSN	1472-6963 ; 1472-6963
ISSN (online)	1472-6963
ISSN	1472-6963
DOI	10.1186/s12913-023-10258-4
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Article ; Online: Gender difference of geographic distribution of physicians in Japan

Kazuki Kimura / Kazuo Inoue / Takahito Ando / Masanori Ito

BMC Health Services Research, Vol 23, Iss 1, Pp 1-

three-point analysis of 1994, 2004 and 2014

2023 Volume 10

Abstract: Abstract Background Japan's medical education system produces 9,000 graduates annually. Despite the government's implementation of several strategies, including increasing the number of doctors trained, the country still struggles with a shortage of ... ...

Abstract	Abstract Background Japan's medical education system produces 9,000 graduates annually. Despite the government's implementation of several strategies, including increasing the number of doctors trained, the country still struggles with a shortage of physicians in rural areas. This study examined this issue, focusing on gender and considering years of physician experience, demographic and geographic factors. Methods We analyzed the Physician Census from 1994, 2004, and 2014, examining data on physicians’ gender and the number of years since licensure. To correct the impact of municipal mergers, the analysis was aligned with the number of municipalities in 2014 (1741). We examined data from each physician (gender and years of medical experience) and analyzed the demographic and geographic distribution trend using Spearman correlation coefficients. We then used the Gini coefficient to evaluate the distribution change of physicians based on gender and years of experience. Results The number of physicians increased 1.29-fold over the 20-year observation period (1.23-fold for male physicians and 2.17-fold for female physicians), and the percentage of female physicians increased from 13.4% to 20.4%. We found that 87.7% of physicians were concentrated in the top 1/3 municipalities in terms of population. The number of female physicians was higher at 91.8% compared to 86.8% for male physicians. The Gini coefficients were lower for veteran physicians of both sexes than for younger physicians. The Gini coefficient for all physicians was 0.315–0.298–0.298 (male physicians: 0.311–0.289–0.283, female physicians: 0.394–0.385–0.395) The Gini coefficients for female compared to male physicians were higher in all age groups, showing that The distribution of female physicians is skewed toward urban areas. Conclusion Female physicians are less distributed in rural areas than male physicians. In addition, despite the fact that the number of female physicians has increased more than male physicians over the past 20 years, the ...
Keywords	Physician ; Gender difference ; Geographic distribution ; Year of experience ; Japan ; Public aspects of medicine ; RA1-1270
Subject code	303
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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