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  1. Article ; Online: Mycoplasma hominis

    Mendoza Cediel, Pablo / Garcia Teruel, David / Viedma Moreno, Esther / Perez Pomata, Maria Teresa

    BMJ case reports

    2024  Volume 17, Issue 4

    Abstract: We report the case of a young, immunocompetent, non-pregnant woman diagnosed with acute abdomen 3 weeks after an ultrasound-guided transvaginal oocyte retrieval (TVOR). Peritoneal fluid, obtained during exploratory laparoscopy, ... ...

    Abstract We report the case of a young, immunocompetent, non-pregnant woman diagnosed with acute abdomen 3 weeks after an ultrasound-guided transvaginal oocyte retrieval (TVOR). Peritoneal fluid, obtained during exploratory laparoscopy, yielded
    MeSH term(s) Female ; Humans ; Mycoplasma hominis ; Oocyte Donation ; Doxycycline ; Clindamycin/therapeutic use ; Peritonitis/drug therapy ; Peritonitis/etiology ; Mycoplasma Infections/diagnosis ; Mycoplasma Infections/drug therapy
    Chemical Substances Doxycycline (N12000U13O) ; Clindamycin (3U02EL437C)
    Language English
    Publishing date 2024-04-16
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-257835
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  2. Article ; Online: Rapid screening of SARS-CoV-2 variants, a key tool for pandemic surveillance.

    Muñoz-Gallego, Irene / Meléndez Carmona, María Ángeles / Martín Higuera, Carmen / Viedma, Esther / Delgado, Rafael / Folgueira, María Dolores

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 11094

    Abstract: The utility of reverse transcription-polymerase chain reaction (RT-PCR) in analysis SARS-COV-2 variants was evaluated. RT-PCR tests were used to analyse the majority of new SARS-CoV-2 cases (n = 9315) in a tertiary hospital (Madrid, Spain) throughout ... ...

    Abstract The utility of reverse transcription-polymerase chain reaction (RT-PCR) in analysis SARS-COV-2 variants was evaluated. RT-PCR tests were used to analyse the majority of new SARS-CoV-2 cases (n = 9315) in a tertiary hospital (Madrid, Spain) throughout 2021. Subsequently, whole genome sequencing (WGS) was conducted on 10.8% of these samples (n = 1002). Notably, the Delta and Omicron variants emerged rapidly. There were no discrepancies between RT-PCR and WGS results. Continuous surveillance of SARS-CoV-2 variants is essential, and RT-PCR is a highly useful method, specially during periods of high COVID-19 incidence. This feasible technique can be implemented in all SARS-CoV-2 laboratories. However, WGS remains the gold standard method for comprehensive detection of all existing SARS-CoV-2 variants.
    MeSH term(s) Humans ; SARS-CoV-2/genetics ; COVID-19/diagnosis ; COVID-19/epidemiology ; Pandemics ; Laboratories
    Language English
    Publishing date 2023-07-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-37866-8
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  3. Article ; Online: Dissemination of a single ST11 clone of OXA-48-producing

    Lázaro-Perona, Fernando / Dahdouh, Elias / Sotillo, Alma / Pérez-Blanco, Verónica / Villa, Jennifer / Viedma, Esther / Ruiz-Carrascoso, Guillermo / Mingorance, Jesús

    Microbial genomics

    2022  Volume 8, Issue 4

    MeSH term(s) Clone Cells ; Hospitals ; Humans ; Klebsiella Infections/epidemiology ; Klebsiella Infections/genetics ; Klebsiella pneumoniae/genetics ; beta-Lactamases/genetics
    Chemical Substances beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2022-09-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2835258-0
    ISSN 2057-5858 ; 2057-5858
    ISSN (online) 2057-5858
    ISSN 2057-5858
    DOI 10.1099/mgen.0.000808
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  4. Article: Microbiological and Molecular Features Associated with Persistent and Relapsing

    Muñoz-Gallego, Irene / Meléndez-Carmona, María Ángeles / Lora-Tamayo, Jaime / Garrido-Allepuz, Carlos / Chaves, Fernando / Sebastián, Virginia / Viedma, Esther

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 8

    Abstract: Background: Persistent and relapsing prosthetic joint infection (PJI) due to : Methods: Initial and second : Results: Recurrent : Conclusions: S. ... ...

    Abstract Background: Persistent and relapsing prosthetic joint infection (PJI) due to
    Methods: Initial and second
    Results: Recurrent
    Conclusions: S. aureus
    Language English
    Publishing date 2022-08-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11081119
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  5. Article ; Online: Rapid screening of SARS-CoV-2 variants, a key tool for pandemic surveillance

    Irene Muñoz-Gallego / María Ángeles Meléndez Carmona / Carmen Martín Higuera / Esther Viedma / Rafael Delgado / María Dolores Folgueira

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Volume 5

    Abstract: Abstract The utility of reverse transcription-polymerase chain reaction (RT-PCR) in analysis SARS-COV-2 variants was evaluated. RT-PCR tests were used to analyse the majority of new SARS-CoV-2 cases (n = 9315) in a tertiary hospital (Madrid, Spain) ... ...

    Abstract Abstract The utility of reverse transcription-polymerase chain reaction (RT-PCR) in analysis SARS-COV-2 variants was evaluated. RT-PCR tests were used to analyse the majority of new SARS-CoV-2 cases (n = 9315) in a tertiary hospital (Madrid, Spain) throughout 2021. Subsequently, whole genome sequencing (WGS) was conducted on 10.8% of these samples (n = 1002). Notably, the Delta and Omicron variants emerged rapidly. There were no discrepancies between RT-PCR and WGS results. Continuous surveillance of SARS-CoV-2 variants is essential, and RT-PCR is a highly useful method, specially during periods of high COVID-19 incidence. This feasible technique can be implemented in all SARS-CoV-2 laboratories. However, WGS remains the gold standard method for comprehensive detection of all existing SARS-CoV-2 variants.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Carbapenemase-Producing

    Cañada-García, Javier E / Ramírez de Arellano, Eva / Jiménez-Orellana, Miguel / Viedma, Esther / Sánchez, Aida / Alhambra, Almudena / Villa, Jennifer / Delgado-Iribarren, Alberto / Bautista, Verónica / Lara, Noelia / García-Cobos, Silvia / Aracil, Belén / Cercenado, Emilia / Pérez-Vázquez, María / Oteo-Iglesias, Jesús

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 1

    Abstract: During the COVID-19 pandemic, intensive care units (ICUs) operated at or above capacity, and the number of ICU patients coinfected by nosocomial microorganisms increased. Here, we characterize the population structure and resistance mechanisms of ... ...

    Abstract During the COVID-19 pandemic, intensive care units (ICUs) operated at or above capacity, and the number of ICU patients coinfected by nosocomial microorganisms increased. Here, we characterize the population structure and resistance mechanisms of carbapenemase-producing
    Language English
    Publishing date 2023-01-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12010107
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  7. Article: Genomic Analysis of Ceftazidime/Avibactam-Resistant GES-Producing Sequence Type 235

    Recio, Raúl / Villa, Jennifer / González-Bodí, Sara / Brañas, Patricia / Orellana, María Ángeles / Mancheño-Losa, Mikel / Lora-Tamayo, Jaime / Chaves, Fernando / Viedma, Esther

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 7

    Abstract: The emergence of ceftazidime/avibactam (CZA) resistance among Guiana extended- ... ...

    Abstract The emergence of ceftazidime/avibactam (CZA) resistance among Guiana extended-spectrum
    Language English
    Publishing date 2022-06-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11070871
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  8. Article ; Online: Clinical and bacterial characteristics of Pseudomonas aeruginosa affecting the outcome of patients with bacteraemic pneumonia.

    Recio, Raúl / Viedma, Esther / González-Bodí, Sara / Villa, Jennifer / Orellana, María Ángeles / Mancheño-Losa, Mikel / Lora-Tamayo, Jaime / Chaves, Fernando

    International journal of antimicrobial agents

    2021  Volume 58, Issue 6, Page(s) 106450

    Abstract: Few studies have assessed the clinical and bacterial characteristics of Pseudomonas aeruginosa (PA) bacteraemic pneumonia (BP) episodes. This study analysed all non-duplicate PA-BP episodes from a tertiary hospital in 2013-2017. Epidemiology, clinical ... ...

    Abstract Few studies have assessed the clinical and bacterial characteristics of Pseudomonas aeruginosa (PA) bacteraemic pneumonia (BP) episodes. This study analysed all non-duplicate PA-BP episodes from a tertiary hospital in 2013-2017. Epidemiology, clinical data, antimicrobial therapy and outcomes were recorded. Whole-genome sequencing was performed on PA blood isolates. The impact on early and late overall mortality of host, antimicrobial treatment and pathogen factors was assessed by multivariate logistic regression analysis. Of 55 PA-BP episodes, 32 (58.2%) were caused by extensively drug-resistant (XDR) PA. ST175 (32.7%) and ST235 (25.5%) were the most frequent high-risk clones. β-Lactamases/carbapenemases were detected in 29 isolates, including bla
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bacteremia/drug therapy ; Bacteremia/microbiology ; Bacteremia/mortality ; Bacterial Proteins/genetics ; Drug Resistance, Multiple, Bacterial/genetics ; Female ; Genome, Bacterial/genetics ; Humans ; Male ; Microbial Sensitivity Tests ; Middle Aged ; Molecular Epidemiology ; O Antigens/genetics ; Pneumonia, Bacterial/drug therapy ; Pneumonia, Bacterial/microbiology ; Pneumonia, Bacterial/mortality ; Pseudomonas Infections/drug therapy ; Pseudomonas Infections/epidemiology ; Pseudomonas Infections/mortality ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/genetics ; Pseudomonas aeruginosa/pathogenicity ; Tertiary Care Centers ; Whole Genome Sequencing ; beta-Lactamases/genetics
    Chemical Substances Anti-Bacterial Agents ; Bacterial Proteins ; O Antigens ; beta-Lactamases (EC 3.5.2.6) ; carbapenemase (EC 3.5.2.6)
    Language English
    Publishing date 2021-10-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1093977-5
    ISSN 1872-7913 ; 0924-8579
    ISSN (online) 1872-7913
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2021.106450
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    Zs.A 3368: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  9. Article ; Online: Intraosteoblastic activity of levofloxacin and rifampin alone and in combination against clinical isolates of meticillin-susceptible Staphylococcus aureus causing prosthetic joint infection.

    Meléndez-Carmona, María Ángeles / Muñoz-Gallego, Irene / Viedma, Esther / Lora-Tamayo, Jaime / Chaves, Fernando

    International journal of antimicrobial agents

    2019  Volume 54, Issue 3, Page(s) 356–360

    Abstract: Background: Staphylococcus aureus may invade and persist intracellularly in prosthetic joint infections (PJIs). Despite optimized treatments with levofloxacin plus rifampin, the intracellular reservoir may lead to infection relapse. This study assessed ... ...

    Abstract Background: Staphylococcus aureus may invade and persist intracellularly in prosthetic joint infections (PJIs). Despite optimized treatments with levofloxacin plus rifampin, the intracellular reservoir may lead to infection relapse. This study assessed the intracellular activity of levofloxacin and rifampin in an in-vitro model of human osteoblastic infection.
    Methods: Ten meticillin-susceptible S. aureus strains were used to infect osteoblastic MG63 cells. Osteoblasts were challenged with rifampin and levofloxacin at cortical and cancellous bone concentrations. Efficacy was measured as the intracellular counts of colony-forming units (log
    Results: All regimes led to a significant decrease in CFU count compared with controls (1-2 log
    Conclusions: Levofloxacin plus rifampin had good intracellular activity against S. aureus. However, from the intracellular perspective, the addition of rifampin to levofloxacin showed no benefit but could account for an increased number of SCVs.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Cell Line ; Colony Count, Microbial ; Humans ; Levofloxacin/pharmacology ; Microbial Sensitivity Tests ; Microbial Viability/drug effects ; Models, Theoretical ; Osteoarthritis/microbiology ; Osteoblasts/microbiology ; Prosthesis-Related Infections/microbiology ; Rifampin/pharmacology ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/drug effects
    Chemical Substances Anti-Bacterial Agents ; Levofloxacin (6GNT3Y5LMF) ; Rifampin (VJT6J7R4TR)
    Language English
    Publishing date 2019-06-26
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1093977-5
    ISSN 1872-7913 ; 0924-8579
    ISSN (online) 1872-7913
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2019.06.018
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  10. Article ; Online: Predictors of Mortality in Bloodstream Infections Caused by Pseudomonas aeruginosa and Impact of Antimicrobial Resistance and Bacterial Virulence.

    Recio, Raúl / Mancheño, Mikel / Viedma, Esther / Villa, Jennifer / Orellana, María Ángeles / Lora-Tamayo, Jaime / Chaves, Fernando

    Antimicrobial agents and chemotherapy

    2020  Volume 64, Issue 2

    Abstract: Whether multidrug resistance (MDR) is associated with mortality in patients ... ...

    Abstract Whether multidrug resistance (MDR) is associated with mortality in patients with
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Bacteremia/drug therapy ; Bacteremia/microbiology ; Bacteremia/mortality ; Drug Resistance, Bacterial ; Female ; Humans ; Male ; Pseudomonas Infections/drug therapy ; Pseudomonas Infections/microbiology ; Pseudomonas Infections/mortality ; Pseudomonas aeruginosa/drug effects
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2020-01-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/AAC.01759-19
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    Einzelsignatur: Show issues

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