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  1. Article ; Online: Septic shock due to invasive pulmonary aspergillosis without conventional risk factors.

    Shin, Kyung Eun / Park, Shinhee / Baek, Ae-Rin

    Acute and critical care

    2023  Volume 38, Issue 2, Page(s) 238–241

    Language English
    Publishing date 2023-05-25
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3003021-3
    ISSN 2586-6060 ; 2586-6052
    ISSN (online) 2586-6060
    ISSN 2586-6052
    DOI 10.4266/acc.2023.00437
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Complete chloroplast genome sequence of the liverwort,

    Lee, Shin Ae / Park, Seung-Jin / Seo, Hyemin / Kim, Changkyun / Lee, Kyung Jun

    Mitochondrial DNA. Part B, Resources

    2023  Volume 8, Issue 6, Page(s) 695–698

    Abstract: ... Porella ... ...

    Abstract Porella grandiloba
    Language English
    Publishing date 2023-06-26
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2023.2225655
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  3. Article ; Online: Optimizing the Hospital Blood Bank Stock in Korea: A Comparative Analysis of the Uniform 5-Day Stock Index and a Novel Blood Stock Index.

    Park, Seo-Jin / Lim, Young Ae / Kim, Kyung-Hee

    Annals of laboratory medicine

    2023  Volume 44, Issue 3, Page(s) 262–270

    Abstract: Background: Maintaining optimal blood inventory levels in hospitals is important to prevent blood shortage and wastage. We aimed to provide an efficient blood inventory management strategy for hospital blood banks nation-wide by comparing the current ... ...

    Abstract Background: Maintaining optimal blood inventory levels in hospitals is important to prevent blood shortage and wastage. We aimed to provide an efficient blood inventory management strategy for hospital blood banks nation-wide by comparing the current use of 5-day issuable stock (IS) with Lim's IS as a novel target IS.
    Methods: The average and CV of daily usage (DU) were calculated from information entered into Korea's Blood Management System by 194 participating hospitals in 2019 and 2020. Using these data, Lim's IS was calculated by determining the simulated annual average blood shortage day nearest to 1 for each blood group in each hospital. The 5-day IS (5IS) was estimated by multiplying the average DU in 2018 by five to count the shortage days in 2019.
    Results: The average DU (0.3-231.3 units) and corresponding CV (0.33-7.14) in the participating hospitals were inversely proportional (r=-0.699 to -0.695). The hypothetical averages of 5IS and Lim's IS were 27.0±41.2 and 24.7±20.8, respectively (
    Conclusions: While 5IS was unacceptable for universal application, Lim's IS remained near one shortage day and is considered more efficient than 5IS. Hospitals should implement indicators that consider DU and its variations. This is the first study to introduce Lim's IS as an indicator of optimal blood inventory, and the data are expected to provide guidance for effective blood inventory management nationwide, particularly during blood shortages.
    MeSH term(s) Humans ; Blood Banks ; Hospitals ; Republic of Korea
    Language English
    Publishing date 2023-12-15
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2677441-0
    ISSN 2234-3814 ; 2234-3814
    ISSN (online) 2234-3814
    ISSN 2234-3814
    DOI 10.3343/alm.2023.0242
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  4. Article ; Online: Incidence of harmful algal blooms in pristine subtropical ocean

    Min-Sun Lee / Kyung-Ae Park / Guebuem Kim

    Frontiers in Marine Science, Vol

    a satellite remote sensing approach (Jeju Island)

    2023  Volume 10

    Abstract: Despite the increasing numbers of red tide events in the pristine subtropical ocean, a paucity of previous observations has limited understanding of harmful algae in the seas around the Korean Peninsula. Therefore, using six years (2012–2017) of ... ...

    Abstract Despite the increasing numbers of red tide events in the pristine subtropical ocean, a paucity of previous observations has limited understanding of harmful algae in the seas around the Korean Peninsula. Therefore, using six years (2012–2017) of Geostationary Ocean Color Imager (GOCI) satellite data, we characterized the red tides around Jeju Island, a volcanic island located near the paths of the Jeju Warm Current and Tsushima Warm Current, using the Normalized Red Tide Index (NRTI) method. The seawater around Jeju Island has for a long time been considered to be very clear, with relatively low suspended particulate matter concentrations and few harmful algae. Nonetheless, the satellite-based NRTI detection method used in this study detected and supported the existence of red tides in the coastal region around Jeju Island. Analysis of the red tide distribution showed that red tide first began to appear near the western coast of Jeju Island, then developed in the northern and eastern coastal regions, and finally vanished in the eastern coastal region. The monthly averages of the NRTI demonstrated a bloom event from April to May in every year. Additional fall blooms were detected in August–September, particularly in 2013 and 2016. The NRTI revealed strong interannual variations. The longest blooms occurred in 2015, and the most comprehensive and strongest event occurred in the spring of 2016. The latter three years (2015–2017) had much higher NRTI than the former three years (2012–2014). The probability of red tide occurrence at a given point during the 6-year study period revealed spatial differences. Relatively high probability of 0.3–0.5 was determined along the northern coastal region, whereas low probability of less than 0.2 was found along the southern region. Ground truth data also showed more frequent observations and higher red tide cell densities along the northern coast. Changes in NRTI in spring are positively correlated with changes in ENSO indices in winter. This study is the first to use a ...
    Keywords red tide ; Geostationary Ocean Color Imager (GOCI) ; ocean color ; red tide index ; Jeju Island ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
    Subject code 551
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Molecular Activity of Inflammation and Epithelial-Mesenchymal Transition in the Microenvironment of Ulcerative Colitis.

    Jun, Yu Kyung / Kim, Nayoung / Yoon, Hyuk / Park, Ji Hyun / Kim, Hyung Kyung / Choi, Yonghoon / Lee, Ji Ae / Shin, Cheol Min / Park, Young Soo / Lee, Dong Ho

    Gut and liver

    2024  

    Abstract: Background/aims: : The genetic expression in the active inflammatory regions is increased in ulcerative colitis (UC) with endoscopic activity. The aim of this study was to investigate the molecular activity of inflammation and tissue remodeling markers ... ...

    Abstract Background/aims: : The genetic expression in the active inflammatory regions is increased in ulcerative colitis (UC) with endoscopic activity. The aim of this study was to investigate the molecular activity of inflammation and tissue remodeling markers in endoscopically inflamed and uninflamed regions of UC.
    Methods: : Patients with UC (n=47) and controls (n=20) were prospectively enrolled at the Seoul National University Bundang Hospital. Inflamed tissue was obtained at the most active lesion, and uninflamed tissue was collected from approximately 15 cm above the upper end of the active lesion via colonoscopic biopsies. The messenger RNA expression levels of transforming growth factor β (
    Results: : The messenger RNA expressions of
    Conclusions: : Endoscopic activity in UC suggests inflammation and tissue remodeling of uninflamed regions similar to inflamed regions (ClinicalTrials.gov, NCT05653011).
    Language English
    Publishing date 2024-02-22
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2399010-7
    ISSN 2005-1212 ; 1976-2283
    ISSN (online) 2005-1212
    ISSN 1976-2283
    DOI 10.5009/gnl230283
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  6. Article ; Online: Cephalosporin-induced encephalopathy in patients with hematologic malignancies: a significant concern.

    Park, Young Seob / Kim, Min Kyoung / Lee, Kyung Hee / Koh, Sung Ae / Jung, Ji Yoon / Jang, Byeong Il / Lee, Se-Jin

    Journal of Yeungnam medical science

    2023  Volume 40, Issue Suppl, Page(s) S137–S141

    Language English
    Publishing date 2023-11-14
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2799-8010
    ISSN (online) 2799-8010
    DOI 10.12701/jyms.2023.00864
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  7. Article ; Online: Application of Non-stationary Extreme Value Analysis to Satellite-Observed Sea Surface Temperature Data for Past Decades

    Eun-Young Lee / Kyung-Ae Park

    Frontiers in Marine Science, Vol

    2022  Volume 8

    Abstract: Extreme value analysis (EVA) has been extensively used to understand and predict long-term return extreme values. This study provides the first approach to EVA using satellite-observed sea surface temperature (SST) data over the past decades. ... ...

    Abstract Extreme value analysis (EVA) has been extensively used to understand and predict long-term return extreme values. This study provides the first approach to EVA using satellite-observed sea surface temperature (SST) data over the past decades. Representative EVA methods were compared to select an appropriate method to derive SST extremes of the East/Japan Sea (EJS). As a result, the peaks-over-threshold (POT) method showed better performance than the other methods. The Optimum Interpolation Sea Surface Temperature (OISST) database was used to calculate the 100-year-return SST values in the EJS. The calculated SST extremes were 1.60–3.44°C higher than the average value of the upper 5th-percentile satellite-observed SSTs over the past decades (1982–2018). The monthly distribution of the SST extremes was similar to the known seasonal variation of SSTs in the EJS, but enhanced extreme SSTs exceeding 2°C appeared in early summer and late autumn. The calculated 100-year-return SSTs were compared with the simulation results of the Coupled Model Intercomparison Project 5 (CMIP5) climate model. As a result, the extreme SSTs were slightly smaller than the maximum SSTs of the model data with a negative bias of –0.36°C. This study suggests that the POT method can improve our understanding of future oceanic warming based on statistical approaches using SSTs observed by satellites over the past decades.
    Keywords sea surface temperature (SST) ; extreme value ; peaks-over-threshold (POT) method ; satellite data ; East/Japan Sea (EJS) ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
    Subject code 551
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Estimation of hazardous and noxious substance (toluene) thickness using hyperspectral remote sensing

    Jae-Jin Park / Kyung-Ae Park / Pierre-Yves Foucher / Tae-Sung Kim / Moonjin Lee

    Frontiers in Environmental Science, Vol

    2023  Volume 11

    Abstract: A hazardous noxious substance (HNS) spill accident is one of the most devastating maritime disasters as it is accompanied by toxicity, fire, and explosions in the ocean. To monitor an HNS spill, it is necessary to develop a remote sensing–based HNS ... ...

    Abstract A hazardous noxious substance (HNS) spill accident is one of the most devastating maritime disasters as it is accompanied by toxicity, fire, and explosions in the ocean. To monitor an HNS spill, it is necessary to develop a remote sensing–based HNS monitoring technique that can observe a wide area with high resolution. We designed and performed a ground HNS spill experiment using a hyperspectral sensor to detect HNS spill areas and estimate the spill volume. HNS images were obtained by pouring 1 L of toluene into an outdoor marine pool and observing it with a hyperspectral sensor capable of measuring the shortwave infrared channel installed at a height of approximately 12 m. The pure endmember spectra of toluene and seawater were extracted using principal component analysis and N-FINDR, and a Gaussian mixture model was applied to the toluene abundance fraction. Consequently, a toluene spill area of approximately 2.4317 m2 was detected according to the 36% criteria suitable for HNS detection. The HNS thickness estimation was based on a three-layer two-beam interference theory model. Because toluene has a maximum extinction coefficient of 1.3055 mm at a wavelength of 1,678 nm, the closest 1,676.5 nm toluene reflectance image was used for thickness estimation. Considering the detection area and ground resolution, the amount of leaked toluene was estimated to be 0.9336 L. As the amount of toluene used in the actual ground experiment was 1 L, the accuracy of our estimation is approximately 93.36%. Previous studies on HNS monitoring based on remote sensing are lacking in comparison to those on oil spills. This study is expected to contribute to the establishment of maritime HNS spill response strategies in the near future based on the novel hyperspectral HNS experiment.
    Keywords hazardous noxious substance (HNS) ; toluene ; hyperspectral ; detection ; thickness ; Environmental sciences ; GE1-350
    Subject code 333
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Validation of Image Qualities of a Novel Four-Mice Bed PET System as an Oncological and Neurological Analysis Tool.

    Kang, Kyung Jun / Oh, Se Jong / Nam, Kyung Rok / Ahn, Heesu / Park, Ji-Ae / Lee, Kyo Chul / Choi, Jae Yong

    Journal of imaging

    2021  Volume 7, Issue 3

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2021-02-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2824270-1
    ISSN 2313-433X ; 2313-433X
    ISSN (online) 2313-433X
    ISSN 2313-433X
    DOI 10.3390/jimaging7030043
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  10. Article ; Online: Trichinella spiralis nurse cell formation is regulated via CCR7

    Park, Mi-Kyung / Kang, Shin Ae / Cho, Min-Kyoung / Yu, Hak Sun

    Parasite immunology

    2022  Volume 44, Issue 9, Page(s) e12938

    Abstract: The chemokine receptor CCR7 is a well-established homing receptor for dendritic cells (DCs) and T-cells. Interaction with the CCL19 and CCL21 ligands promotes priming of immune responses in lymphoid tissues; however, the mechanism underlying CCR7-induced ...

    Abstract The chemokine receptor CCR7 is a well-established homing receptor for dendritic cells (DCs) and T-cells. Interaction with the CCL19 and CCL21 ligands promotes priming of immune responses in lymphoid tissues; however, the mechanism underlying CCR7-induced immune responses against helminth parasite infection remains unknown. Thus, we examined the role of CCR7 in generating protective immune responses against intracellular Trichinella spiralis infection. The results showed significantly increased CCR7, CCL19 and CCL21 expression in the muscle tissue compared to that in the intestinal tissue in T. spiralis-infected mice. The CCR7-expressing DC population increased in the mesenteric and peripheral lymph nodes (PLNs) during T. spiralis infection. Notably, the number of CCR7-expressing cells in PLNs increased by more than 30% at 28 days post-infection; however, this increase was significantly inhibited in CCR7-blocked mice treated with CCR7-specific antibodies. T helper 2 (Th2)-and regulatory T (T
    MeSH term(s) Animals ; Cytokines/metabolism ; Dendritic Cells ; Mice ; Receptors, CCR7/metabolism ; Trichinella spiralis ; Trichinellosis
    Chemical Substances Ccr7 protein, mouse ; Cytokines ; Receptors, CCR7
    Language English
    Publishing date 2022-06-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 424444-8
    ISSN 1365-3024 ; 0141-9838
    ISSN (online) 1365-3024
    ISSN 0141-9838
    DOI 10.1111/pim.12938
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    In stock of ZB MED Cologne/Königswinter

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