LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 2367

Search options

  1. Article ; Online: Rates of Positive M-CHAT-R Screenings by Pandemic Birth and Prenatal SARS-CoV-2 Exposure

    Firestein, Morgan R. / Manessis, Angela Gigliotti / Warmingham, Jen / Hu, Yunzhe / Finkel, Morgan A. / Kyle, Margaret / Hussain, Maha / Ahmed, Imaal / Lavallée, Andréane / Solis, Ana / Chaves, Vitoria / Rodriguez, Cynthia / Goldman, Sylvie / Muhle, Rebecca A. / Lee, Seonjoo / Austin, Judy / Silver, Wendy G. / O’Reilly, Kally C. / Bain, Jennifer M. /
    Penn, Anna A. / Veenstra-VanderWeele, Jeremy / Stockwell, Melissa S. / Fifer, William P. / Marsh, Rachel / Monk, Catherine / Shuffrey, Lauren C. / Dumitriu, Dani

    medRxiv

    Abstract: ... in Toddlers-Revised (M-CHAT-R). Data were drawn from the COVID-19 Mother Baby Outcomes (COMBO) Initiative ... Participants completed the M-CHAT-R as part of routine clinical care (COMBO-EHR cohort) or for research ... hospitals between 2018-2023 and who had a valid M-CHAT-R score in their health record. The COMBO-RSCH cohort ...

    Abstract Maternal stress and viral illness during pregnancy are associated with neurodevelopmental conditions in offspring. Children born during the COVID-19 pandemic, including those exposed prenatally to maternal SARS-CoV-2 infections, are reaching the developmental age for the assessment of risk for neurodevelopmental conditions. We examined associations between birth during the COVID-19 pandemic, prenatal exposure to maternal SARS-CoV-2 infection, and rates of positive screenings on the Modified Checklist for Autism in Toddlers-Revised (M-CHAT-R). Data were drawn from the COVID-19 Mother Baby Outcomes (COMBO) Initiative. Participants completed the M-CHAT-R as part of routine clinical care (COMBO-EHR cohort) or for research purposes (COMBO-RSCH cohort). Maternal SARS-CoV-2 status during pregnancy was determined through electronic health records. The COMBO-EHR cohort includes n=1664 children (n=442 historical cohort, n=1222 pandemic cohort; n=997 SARS-CoV-2 unexposed prenatally, n=130 SARS-CoV-2 exposed prenatally) who were born at affiliated hospitals between 2018-2023 and who had a valid M-CHAT-R score in their health record. The COMBO-RSCH cohort consists of n=359 children (n=268 SARS-CoV-2 unexposed prenatally, n=91 SARS-CoV-2 exposed prenatally) born at the same hospitals who enrolled into a prospective cohort study that included administration of the M-CHAT-R at 18-months. Birth during the pandemic was not associated with greater likelihood of a positive M-CHAT-R screen in the COMBO-EHR cohort. Maternal SARS-CoV-2 was associated with lower likelihood of a positive M-CHAT-R screening in adjusted models in the COMBO-EHR cohort (OR=0.40, 95% CI=0.22 - 0.68, p=0.001), while analyses in the COMBO-RSCH cohort yielded similar but non-significant results (OR=0.67, 95% CI=0.31-1.37, p=0.29). These results suggest that children born during the first 18 months of the COVID-19 pandemic and those exposed prenatally to a maternal SARS-CoV-2 infection are not at greater risk for screening positive on the M-CHAT-R.
    Keywords covid19
    Language English
    Publishing date 2024-02-22
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2024.02.20.24302892
    Database COVID19

    Full text online

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Reply to F.M. Muggia.

    Chan, John K / Monk, Bradley J

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2016  Volume 34, Issue 8, Page(s) 882–883

    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Female ; Humans ; Neoplasms, Glandular and Epithelial/drug therapy ; Ovarian Neoplasms/drug therapy
    Language English
    Publishing date 2016-03-10
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.2015.63.4295
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1847: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 650: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases.

    Monk, Brian C / Keniya, Mikhail V

    Journal of fungi (Basel, Switzerland)

    2021  Volume 7, Issue 12

    Abstract: In the original publication, there was a mistake [ ... ]. ...

    Abstract In the original publication, there was a mistake [...].
    Language English
    Publishing date 2021-11-26
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof7121011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Genome-scale metabolic network reconstructions of diverse

    Monk, Jonathan M

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences

    2022  Volume 377, Issue 1861, Page(s) 20210236

    Abstract: Bottom-up approaches to systems biology rely on constructing a mechanistic basis for the biochemical and genetic processes that underlie cellular functions. Genome-scale network reconstructions of metabolism are built from all known metabolic reactions ... ...

    Abstract Bottom-up approaches to systems biology rely on constructing a mechanistic basis for the biochemical and genetic processes that underlie cellular functions. Genome-scale network reconstructions of metabolism are built from all known metabolic reactions and metabolic genes in a target organism. A network reconstruction can be converted into a mathematical format and thus lend itself to mathematical analysis. Genome-scale models (GEMs) of metabolism enable a systems approach to characterize the pan and core metabolic capabilities of the
    MeSH term(s) Escherichia coli/genetics ; Genome ; Genome, Bacterial ; Genomics/methods ; Metabolic Networks and Pathways ; Models, Biological ; Systems Biology/methods
    Language English
    Publishing date 2022-08-22
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 208382-6
    ISSN 1471-2970 ; 0080-4622 ; 0264-3839 ; 0962-8436
    ISSN (online) 1471-2970
    ISSN 0080-4622 ; 0264-3839 ; 0962-8436
    DOI 10.1098/rstb.2021.0236
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Einzelsignatur: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Docosahexaenoic acid.

    Richard, Caroline / Monk, Jennifer M

    Advances in nutrition (Bethesda, Md.)

    2023  Volume 15, Issue 1, Page(s) 100161

    MeSH term(s) Humans ; Docosahexaenoic Acids ; Eicosapentaenoic Acid ; Fatty Acids ; Fish Oils ; Dietary Supplements ; Fatty Acids, Omega-3
    Chemical Substances Docosahexaenoic Acids (25167-62-8) ; Eicosapentaenoic Acid (AAN7QOV9EA) ; Fatty Acids ; Fish Oils ; Fatty Acids, Omega-3
    Language English
    Publishing date 2023-12-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2583634-1
    ISSN 2156-5376 ; 2156-5376
    ISSN (online) 2156-5376
    ISSN 2156-5376
    DOI 10.1016/j.advnut.2023.100161
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Effect of Short-Chain Fatty Acids on Inflammatory and Metabolic Function in an Obese Skeletal Muscle Cell Culture Model.

    Van, Kelsey / Burns, Jessie L / Monk, Jennifer M

    Nutrients

    2024  Volume 16, Issue 4

    Abstract: The fermentation of non-digestible carbohydrates produces short-chain fatty acids (SCFAs), which have been shown to impact both skeletal muscle metabolic and inflammatory function; however, their effects within the obese skeletal muscle microenvironment ... ...

    Abstract The fermentation of non-digestible carbohydrates produces short-chain fatty acids (SCFAs), which have been shown to impact both skeletal muscle metabolic and inflammatory function; however, their effects within the obese skeletal muscle microenvironment are unknown. In this study, we developed a skeletal muscle in vitro model to mimic the critical features of the obese skeletal muscle microenvironment using L6 myotubes co-treated with 10 ng/mL lipopolysaccharide (LPS) and 500 µM palmitic acid (PA) for 24 h ± individual SCFAs, namely acetate, propionate and butyrate at 0.5 mM and 2.5 mM. At the lower SCFA concentration (0.5 mM), all three SCFA reduced the secreted protein level of RANTES, and only butyrate reduced IL-6 protein secretion and the intracellular protein levels of activated (i.e., ratio of phosphorylated-total) NFκB p65 and STAT3 (
    MeSH term(s) Humans ; Propionates/pharmacology ; Interleukin-6/metabolism ; Fatty Acids, Volatile/metabolism ; Obesity ; Butyrates ; Acetates ; Muscle Fibers, Skeletal/metabolism ; Insulin/pharmacology ; Muscle, Skeletal/metabolism ; Glucose/metabolism ; Cell Culture Techniques ; Inflammation Mediators
    Chemical Substances Propionates ; Interleukin-6 ; Fatty Acids, Volatile ; Butyrates ; Acetates ; Insulin ; Glucose (IY9XDZ35W2) ; Inflammation Mediators
    Language English
    Publishing date 2024-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16040500
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Book ; Thesis: Immunhistologische Untersuchung an Tumor- und Normalblasen über die Verteilung der Blutgruppen-Antigene A, B, H, des T-Antigens und des monoklonalen Antikörpers 486 p 3-12

    Mönk, Michael

    1993  

    Author's details vorgelegt von Michael Mönk
    Language German
    Size 31, [23] S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hamburg, Univ., Diss., 1994
    HBZ-ID HT006728917
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    95 D 2968 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Predicting Antimicrobial Resistance and Associated Genomic Features from Whole-Genome Sequencing.

    Monk, Jonathan M

    Journal of clinical microbiology

    2019  Volume 57, Issue 2

    Abstract: Thanks to the genomics revolution, thousands of strain-specific whole-genome sequences are now accessible for a wide range of pathogenic bacteria. This availability enables big data informatics approaches to be used to study the spread and acquisition of ...

    Abstract Thanks to the genomics revolution, thousands of strain-specific whole-genome sequences are now accessible for a wide range of pathogenic bacteria. This availability enables big data informatics approaches to be used to study the spread and acquisition of antimicrobial resistance (AMR). In this issue of the
    MeSH term(s) Anti-Bacterial Agents ; Drug Resistance, Bacterial/drug effects ; Genomics ; Machine Learning ; Salmonella/drug effects ; United States
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2019-01-30
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.01610-18
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1188: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: The Tolerance Model of Non-Inflammatory Immune Competence in Acute Pediatric Malnutrition: Origins, Evidence, Test of Fitness and Growth Potential.

    Woodward, Bill / Hillyer, Lyn M / Monk, Jennifer M

    Nutrients

    2023  Volume 15, Issue 23

    Abstract: The tolerance model rests on the thesis of a physiologically regulated, albeit unsustainable, systemic attempt to adapt to the catabolic challenge posed by acute prepubescent malnutrition even in its severe forms. The model centers on the immunological ... ...

    Abstract The tolerance model rests on the thesis of a physiologically regulated, albeit unsustainable, systemic attempt to adapt to the catabolic challenge posed by acute prepubescent malnutrition even in its severe forms. The model centers on the immunological component of the attempt, positing reorientation toward a non-inflammatory form of competence in place of the classic paradigm of immunological attrition and exhaustion. The foundation of the model was laid in 1990, and sixteen years later it was articulated formally on the basis of a body of evidence centered on T cell cytokines and interventions with cytokine and hormonal mediators. The benefit originally suggested was a reduced risk of autoimmune pathologies consequent to the catabolic release of self-antigens, hence the designation highlighting immune tolerance. Herein, the emergence of the tolerance model is traced from its roots in the recognition that acute malnutrition elicits an endocrine-based systemic adaptive attempt. Thereafter, the growth of the evidence base supporting the model is outlined, and its potential to shed new light on existing information is tested by application to the findings of a published clinical study of acutely malnourished children. Finally, some knowledge gaps pertinent to the model are identified and its potential for growth consonant with evolving perceptions of immunobiology is illustrated.
    MeSH term(s) Humans ; Child ; Malnutrition ; Cytokines ; Immune Tolerance ; T-Lymphocytes
    Chemical Substances Cytokines
    Language English
    Publishing date 2023-11-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15234922
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Physiotherapists' attitudes and beliefs about self-management as part of their management for low back pain.

    Monk, Celia / Sole, Gisela / Perry, Meredith

    Musculoskeletal science & practice

    2023  Volume 64, Page(s) 102727

    Abstract: Background: Perceptually, there is a discrepancy between research evidence and clinical physiotherapy practice for supporting self-management in people with low back pain (LBP).: Objective: This study aimed to explore physiotherapists' understanding ... ...

    Abstract Background: Perceptually, there is a discrepancy between research evidence and clinical physiotherapy practice for supporting self-management in people with low back pain (LBP).
    Objective: This study aimed to explore physiotherapists' understanding of LBP; ascertain their knowledge of self-management concepts; and explore their attitudes and beliefs about supporting self-management for LBP within present physiotherapy practice in private and hospital settings.
    Design: Interpretive Description qualitative methodology, involving in-depth data interpretation to clinical practice, was used.
    Methods: Semi-structured interviews with physiotherapists throughout New Zealand were conducted via video conferencing. Data was analysed and themes were defined.
    Results: Seventeen physiotherapists (24-65 years old), with between one and 40+ years of experience, participated. Four main themes were defined: 1) Evolving understanding of LBP, 2) apportioning responsibility, 3) self-management is important, 4) understanding self-management.
    Conclusion: Novel findings from this research demonstrate examples of attitudes and beliefs that determine when and how self-management for people with LBP is implemented. Due to these attitudes and beliefs, physiotherapists may not consistently provide supported self-management for people with LBP. Participants had good understanding of LBP but lacked a contemporary knowledge of the natural history and tended to apportion responsibility for persistent or recurrent episodes to the person with LBP. Physiotherapists should be encouraged to assimilate more contemporary research evidence into their expectations of recovery for LBP. Further education about the role of physiotherapists in supporting self-management, the core components of self-management, including engagement, and reflection upon individual unconscious bias should be encouraged.
    MeSH term(s) Humans ; Young Adult ; Adult ; Middle Aged ; Aged ; Physical Therapists ; Low Back Pain/therapy ; Self-Management ; Attitude of Health Personnel ; Health Knowledge, Attitudes, Practice
    Language English
    Publishing date 2023-02-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2888772-4
    ISSN 2468-7812
    ISSN (online) 2468-7812
    DOI 10.1016/j.msksp.2023.102727
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5783: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top