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Article ; Online: Projected burden and duration of the 2022 Monkeypox outbreaks in non-endemic countries.

Bisanzio, Donal / Reithinger, Richard

The Lancet. Microbe

2022 Volume 3, Issue 9, Page(s) e643

MeSH term(s)	Disease Outbreaks/prevention & control ; Humans ; Mpox (monkeypox)/epidemiology ; Monkeypox virus
Language	English
Publishing date	2022-06-23
Publishing country	England
Document type	Letter
ISSN	2666-5247
ISSN (online)	2666-5247
DOI	10.1016/S2666-5247(22)00183-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Progress towards the implementation of control programmes for strongyloidiasis in endemic areas: estimation of number of adults in need of ivermectin for strongyloidiasis.

Buonfrate, Dora / Montresor, Antonio / Bisoffi, Zeno / Tamarozzi, Francesca / Bisanzio, Donal

Philosophical transactions of the Royal Society of London. Series B, Biological sciences

2023 Volume 379, Issue 1894, Page(s) 20220433

Abstract: The World Health Organization has started a process to issue guidelines for the control of strongyloidiasis. The guidelines might recommend to implement preventive chemotherapy (PC) at community level (i.e. to all individuals above 5 years of age), over ... ...

Abstract	The World Health Organization has started a process to issue guidelines for the control of strongyloidiasis. The guidelines might recommend to implement preventive chemotherapy (PC) at community level (i.e. to all individuals above 5 years of age), over a defined prevalence threshold. We previously estimated the number of school-age children (SAC) who would need PC. Here we estimate the number of people above 15 years of age who might be included in PC for strongyloidiasis. Based on previous
MeSH term(s)	Child ; Adult ; Humans ; Ivermectin/therapeutic use ; Strongyloidiasis/drug therapy ; Strongyloidiasis/epidemiology ; Strongyloidiasis/prevention & control ; Onchocerciasis/drug therapy ; Onchocerciasis/epidemiology ; Elephantiasis, Filarial/drug therapy ; Elephantiasis, Filarial/epidemiology ; Elephantiasis, Filarial/prevention & control ; Prevalence
Chemical Substances	Ivermectin (70288-86-7)
Language	English
Publishing date	2023-11-27
Publishing country	England
Document type	Journal Article
ZDB-ID	208382-6
ISSN	1471-2970 ; 0080-4622 ; 0264-3839 ; 0962-8436
ISSN (online)	1471-2970
ISSN	0080-4622 ; 0264-3839 ; 0962-8436
DOI	10.1098/rstb.2022.0433
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Article: Living with obstetric fistula: learnings from nine African countries.

Ngongo, Carrie J / Raassen, Thomas J I P / Mahendeka, Marietta / Bisanzio, Donal / Lombard, Ladeisha / Bann, Carla

BMJ global health

2023 Volume 8, Issue 5

MeSH term(s)	Pregnancy ; Female ; Humans ; Obstetric Labor Complications ; Africa ; Fistula
Language	English
Publishing date	2023-05-17
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2059-7908
ISSN	2059-7908
DOI	10.1136/bmjgh-2023-012509
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Article: Non-household environments make a major contribution to dengue transmission: Implications for vector control.

Peña-García, Victor Hugo / Desiree LaBeaud, A / Ndenga, Bryson A / Mutuku, Francis M / Bisanzio, Donal A / Mordecai, Erin A / Andrews, Jason R

medRxiv : the preprint server for health sciences

2024

Abstract: Aedes-borne pathogens have been increasing in incidence in recent decades despite vector control activities implemented in endemic settings. Vector control ... ...

Abstract	Aedes-borne pathogens have been increasing in incidence in recent decades despite vector control activities implemented in endemic settings. Vector control for
Language	English
Publishing date	2024-01-10
Publishing country	United States
Document type	Preprint
DOI	10.1101/2024.01.08.24301016
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Article ; Online: Antioxidant Effect of a Dietary Supplement Containing Fermentative S-Acetyl-Glutathione and Silybin in Dogs with Liver Disease.

Martello, Elisa / Perondi, Francesca / Bisanzio, Donal / Lippi, Ilaria / Meineri, Giorgia / Gabriele, Valeria

Veterinary sciences

2023 Volume 10, Issue 2

Abstract: Oxidative stress is often involved in liver disease progression. Liver is the primary site for the synthesis of glutathione (GSH), the major intracellular antioxidant. GSH erythrocyte concentration can decrease in case of liver damage. So, the use of ... ...

Abstract	Oxidative stress is often involved in liver disease progression. Liver is the primary site for the synthesis of glutathione (GSH), the major intracellular antioxidant. GSH erythrocyte concentration can decrease in case of liver damage. So, the use of food supplements with antioxidant capacity has been reported in the veterinary literature. In this case-control study, we tested a new supplement containing S-acetyl-glutathione (SAG), silybin, and other antioxidant ingredients in dogs affected by liver disease. After two weeks of supplement administration, we were able to report a significant increase in the level of erythrocyte GSH in the treated (TRT) group, nearly reaching the physiological limit at the end of the study. In addition, most of the key liver parameters are significantly reduced in the TRT group by the end of the trial. The results of this study support the effectiveness of the tested complementary feed, which may be helpful in managing dogs with liver conditions.
Language	English
Publishing date	2023-02-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2768971-2
ISSN	2306-7381 ; 2306-7381
ISSN (online)	2306-7381
ISSN	2306-7381
DOI	10.3390/vetsci10020131
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Article ; Online: The epidemiology of diphtheria in Haiti, December 2014-June 2021: A spatial modeling analysis.

Ikejezie, Juniorcaius / Langley, Tessa / Lewis, Sarah / Bisanzio, Donal / Phalkey, Revati

PloS one

2022 Volume 17, Issue 8, Page(s) e0273398

Abstract: Background: Haiti has been experiencing a resurgence of diphtheria since December 2014. Little is known about the factors contributing to the spread and persistence of the disease in the country. Geographic information systems (GIS) and spatial analysis ...

Abstract	Background: Haiti has been experiencing a resurgence of diphtheria since December 2014. Little is known about the factors contributing to the spread and persistence of the disease in the country. Geographic information systems (GIS) and spatial analysis were used to characterize the epidemiology of diphtheria in Haiti between December 2014 and June 2021. Methods: Data for the study were collected from official and open-source databases. Choropleth maps were developed to understand spatial trends of diphtheria incidence in Haiti at the commune level, the third administrative division of the country. Spatial autocorrelation was assessed using the global Moran's I. Local indicators of spatial association (LISA) were employed to detect areas with spatial dependence. Ordinary least squares (OLS) and geographically weighted regression (GWR) models were built to identify factors associated with diphtheria incidence. The performance and fit of the models were compared using the adjusted r-squared (R2) and the corrected Akaike information criterion (AICc). Results: From December 2014 to June 2021, the average annual incidence of confirmed diphtheria was 0.39 cases per 100,000 (range of annual incidence = 0.04-0.74 per 100,000). During the study period, diphtheria incidence presented weak but significant spatial autocorrelation (I = 0.18, p<0.001). Although diphtheria cases occurred throughout Haiti, nine communes were classified as disease hotspots. In the regression analyses, diphtheria incidence was positively associated with health facility density (number of facilities per 100,000 population) and degree of urbanization (proportion of urban population). Incidence was negatively associated with female literacy. The GWR model considerably improved model performance and fit compared to the OLS model, as indicated by the higher adjusted R2 value (0.28 v 0.15) and lower AICc score (261.97 v 267.13). Conclusion: This study demonstrates that GIS and spatial analysis can support the investigation of epidemiological patterns. Furthermore, it shows that diphtheria incidence exhibited spatial variability in Haiti. The disease hotspots and potential risk factors identified in this analysis could provide a basis for future public health interventions aimed at preventing and controlling diphtheria transmission.
MeSH term(s)	Diphtheria/epidemiology ; Female ; Haiti/epidemiology ; Humans ; Least-Squares Analysis ; Spatial Analysis ; Spatial Regression
Language	English
Publishing date	2022-08-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0273398
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The epidemiology of diphtheria in Haiti, December 2014-June 2021

Juniorcaius Ikejezie / Tessa Langley / Sarah Lewis / Donal Bisanzio / Revati Phalkey

PLoS ONE, Vol 17, Iss 8, p e

A spatial modeling analysis.

2022 Volume 0273398

Abstract: Background Haiti has been experiencing a resurgence of diphtheria since December 2014. Little is known about the factors contributing to the spread and persistence of the disease in the country. Geographic information systems (GIS) and spatial analysis ... ...

Abstract	Background Haiti has been experiencing a resurgence of diphtheria since December 2014. Little is known about the factors contributing to the spread and persistence of the disease in the country. Geographic information systems (GIS) and spatial analysis were used to characterize the epidemiology of diphtheria in Haiti between December 2014 and June 2021. Methods Data for the study were collected from official and open-source databases. Choropleth maps were developed to understand spatial trends of diphtheria incidence in Haiti at the commune level, the third administrative division of the country. Spatial autocorrelation was assessed using the global Moran's I. Local indicators of spatial association (LISA) were employed to detect areas with spatial dependence. Ordinary least squares (OLS) and geographically weighted regression (GWR) models were built to identify factors associated with diphtheria incidence. The performance and fit of the models were compared using the adjusted r-squared (R2) and the corrected Akaike information criterion (AICc). Results From December 2014 to June 2021, the average annual incidence of confirmed diphtheria was 0.39 cases per 100,000 (range of annual incidence = 0.04-0.74 per 100,000). During the study period, diphtheria incidence presented weak but significant spatial autocorrelation (I = 0.18, p<0.001). Although diphtheria cases occurred throughout Haiti, nine communes were classified as disease hotspots. In the regression analyses, diphtheria incidence was positively associated with health facility density (number of facilities per 100,000 population) and degree of urbanization (proportion of urban population). Incidence was negatively associated with female literacy. The GWR model considerably improved model performance and fit compared to the OLS model, as indicated by the higher adjusted R2 value (0.28 v 0.15) and lower AICc score (261.97 v 267.13). Conclusion This study demonstrates that GIS and spatial analysis can support the investigation of epidemiological patterns. ...
Keywords	Medicine ; R ; Science ; Q
Subject code	910
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Long-term effects of a diet supplement containing

Gabriele, Valeria / Bisanzio, Donal / Riva, Antonella / Meineri, Giorgia / Adami, Raffaella / Martello, Elisa

Natural product research

2022 Volume 37, Issue 11, Page(s) 1782–1786

Abstract: Dogs are commonly affected by Osteoarthritis (OA). Different approaches can be used to alleviate animals' symptoms. In this randomised, placebo-controlled and double-blind clinical trial, we performed a three months follow-up study assessing the efficacy ...

Abstract	Dogs are commonly affected by Osteoarthritis (OA). Different approaches can be used to alleviate animals' symptoms. In this randomised, placebo-controlled and double-blind clinical trial, we performed a three months follow-up study assessing the efficacy of a food supplement containing natural ingredients (
MeSH term(s)	Animals ; Dogs ; Boswellia ; Cannabis ; Diet ; Dietary Supplements ; Double-Blind Method ; Follow-Up Studies ; Glutathione ; Osteoarthritis/drug therapy ; Osteoarthritis/veterinary ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use
Chemical Substances	Glutathione (GAN16C9B8O) ; Plant Extracts
Language	English
Publishing date	2022-09-06
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial, Veterinary
ZDB-ID	2185747-7
ISSN	1478-6427 ; 1478-6419
ISSN (online)	1478-6427
ISSN	1478-6419
DOI	10.1080/14786419.2022.2119967
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Article ; Online: Long-term effects of a diet supplement containing Cannabis sativa oil and Boswellia serrata in dogs with osteoarthritis following physiotherapy treatments: a randomised, placebo-controlled and double-blind clinical trial

Gabriele, Valeria / Bisanzio, Donal / Riva, Antonella / Meineri, Giorgia / Adami, Raffaella / Martello, Elisa

Natural Product Research. 2023 June 3, v. 37, no. 11 p.1782-1786

2023

Abstract: Dogs are commonly affected by Osteoarthritis (OA). Different approaches can be used to alleviate animals’ symptoms. In this randomised, placebo-controlled and double-blind clinical trial, we performed a three months follow-up study assessing the efficacy ...

Abstract	Dogs are commonly affected by Osteoarthritis (OA). Different approaches can be used to alleviate animals’ symptoms. In this randomised, placebo-controlled and double-blind clinical trial, we performed a three months follow-up study assessing the efficacy of a food supplement containing natural ingredients (Cannabis sativa oil, Boswellia serrata Roxb. Phytosome® and Zingiber officinale extract) in dogs with OA after the interruption of physiotherapy that was performed during the previous three months. Inflammation and oxidative stress were reduced in the treated group (higher glutathione (GSH) and lower C-reactive protein [CRP] levels in blood) as well as chronic pain.
Keywords	Boswellia serrata ; C-reactive protein ; Cannabis sativa ; blood ; clinical trials ; dietary supplements ; glutathione ; inflammation ; oils ; osteoarthritis ; oxidative stress ; pain ; physical therapy ; research ; chronic pain ; clinical trial
Language	English
Dates of publication	2023-0603
Size	p. 1782-1786.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	2185747-7
ISSN	1478-6427 ; 1478-6419
ISSN (online)	1478-6427
ISSN	1478-6419
DOI	10.1080/14786419.2022.2119967
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Living with obstetric fistula

Donal Bisanzio / Carla Bann / Carrie J Ngongo / Thomas J I P Raassen / Marietta Mahendeka / Ladeisha Lombard

BMJ Global Health, Vol 8, Iss

learnings from nine African countries

2023 Volume 5

Keywords	Medicine (General) ; R5-920 ; Infectious and parasitic diseases ; RC109-216
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	BMJ Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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