LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 301

Search options

  1. Article ; Online: Hirami lemon (

    Tsai, Po-Heng / Wu, Pei-Chen / Li, Hui-Ru / Senthil Kumar, K J / Wang, Sheng-Yang

    Food & function

    2023  Volume 14, Issue 16, Page(s) 7535–7549

    Abstract: ... Citrus ... ...

    Abstract Citrus reticulata
    Language English
    Publishing date 2023-08-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d3fo01301d
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 7872: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Limonene protects human skin keratinocytes against UVB-induced photodamage and photoaging by activating the Nrf2-dependent antioxidant defense system.

    Kumar, K J Senthil / Vani, M Gokila / Wang, Sheng-Yang

    Environmental toxicology

    2022  Volume 37, Issue 12, Page(s) 2897–2909

    Abstract: Long term exposure to solar ultraviolet B (UVB) radiation is one of the primary factors of premature skin aging and is referred to as photoaging. Also, mammalian skin exposed to UVB triggers an increase in production of α-melanocyte-stimulating hormone ( ... ...

    Abstract Long term exposure to solar ultraviolet B (UVB) radiation is one of the primary factors of premature skin aging and is referred to as photoaging. Also, mammalian skin exposed to UVB triggers an increase in production of α-melanocyte-stimulating hormone (α-MSH), which is critically involved in the pathogenesis of hyperpigmentary skin diseases. This study investigated the protective effect of limonene on UVB-induced photodamage and photoaging in immortalized human skin keratinocytes (HaCaT) in vitro. Initially, we determined cell viability and levels of reactive oxygen species (ROS) in UVB-irradiated HaCaT cells. Pretreatment with limonene increased cell viability followed by inhibition of intracellular ROS generation in UVB-irradiated HaCaT cells. Interestingly, the antioxidative activity of limonene was directly correlated with an increase in expression of endogenous antioxidants, including heme oxygenase 1 (HO-1), NAD(P)H:quinone oxidoreductase 1 (NQO-1), and γ-glutamylcysteine synthetase (γ-GCLC), which was associated with enhanced nuclear translocation and activation of NF-E2-related factor-2 (Nrf2). Indeed, Nrf2 knockdown reduced limonene's protective effects. Additionally, we observed that limonene treatment inhibited UVB-induced α-MSH secretion followed by inhibition of proopiomelanocortin (POMC) via suppression of p53 transcriptional activation. Moreover, limonene prevented UVB-mediated depletion of tight junction regulatory proteins, including occludin and zonula occludens-1. On the other hand, limonene treatment significantly decreased matrix metalloproteinase-2 levels in UVB-irradiated HaCaT cells. Based on these results, limonene may have a dermato-protective effect in skin cells by activating the Nrf2-dependent cellular antioxidant defense system.
    MeSH term(s) Humans ; alpha-MSH/metabolism ; Antioxidants/metabolism ; Keratinocytes ; Limonene/pharmacology ; Matrix Metalloproteinase 2/metabolism ; NF-E2-Related Factor 2/metabolism ; Reactive Oxygen Species/metabolism ; Skin Aging ; Skin Diseases ; Ultraviolet Rays/adverse effects ; HaCaT Cells
    Chemical Substances alpha-MSH (581-05-5) ; Antioxidants ; Limonene (9MC3I34447) ; Matrix Metalloproteinase 2 (EC 3.4.24.24) ; NF-E2-Related Factor 2 ; Reactive Oxygen Species
    Language English
    Publishing date 2022-09-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1463449-1
    ISSN 1522-7278 ; 1520-4081
    ISSN (online) 1522-7278
    ISSN 1520-4081
    DOI 10.1002/tox.23646
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2676: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Antcin-B, a phytosterol-like compound from Taiwanofungus camphoratus inhibits SARS-CoV-2 3-chymotrypsin-like protease (3CL

    Dakpa, Gyaltsen / Kumar, K J Senthil / Nelen, Jochem / Pérez-Sánchez, Horacio / Wang, Sheng-Yang

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 17106

    Abstract: Despite the remarkable development of highly effective vaccines, including mRNA-based vaccines, within a limited timeframe, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not been entirely ... ...

    Abstract Despite the remarkable development of highly effective vaccines, including mRNA-based vaccines, within a limited timeframe, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not been entirely eradicated. Thus, it is crucial to identify new effective anti-3CL
    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19 ; Chymases ; Protease Inhibitors/chemistry ; Vaccines ; Molecular Docking Simulation ; Antiviral Agents/therapeutic use ; Molecular Dynamics Simulation
    Chemical Substances Chymases (EC 3.4.21.39) ; Protease Inhibitors ; Vaccines ; Antiviral Agents
    Language English
    Publishing date 2023-10-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-44476-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: New analytical strategies amplified with carbon-based nanomaterial for sensing food pollutants.

    J, Mary Isabella Sonali / S, Subhashree / Senthil Kumar, P / K, Veena Gayathri

    Chemosphere

    2022  Volume 295, Page(s) 133847

    Abstract: The most significant topic currently under the moonlight is Nanobiotechnology and engineered nanomaterials. The novel characteristics displayed by engineered Nanomaterials, especially carbon-based nanomaterials, have spurred interest in its potential ... ...

    Abstract The most significant topic currently under the moonlight is Nanobiotechnology and engineered nanomaterials. The novel characteristics displayed by engineered Nanomaterials, especially carbon-based nanomaterials, have spurred interest in its potential application in the food industry. It has provided opportunities for finding solutions to the long-standing challenges in the food industry to assess food safety, maintain food quality, extend the shelf life of produce, and efficiently deliver nutrients. Nanomaterials can be incorporated in food sensors facilitating efficient monitoring of crop maturity and detecting biological and chemical contaminants. When integrated into food packages, nanomaterials could aid in assessing the freshness and improving the quality of packaged foods. In addition, more efficient delivery of nutrients could be possible in foods fortified using nano compounds. The initial section of this review gives an overview of the broad application of nanotechnology in the food industry and carbon-based nanomaterials. The latter part focuses on nanotechnology in biosensors for food safety and quality monitoring.
    MeSH term(s) Carbon ; Environmental Pollutants ; Food Safety ; Nanostructures/chemistry ; Nanotechnology
    Chemical Substances Environmental Pollutants ; Carbon (7440-44-0)
    Language English
    Publishing date 2022-02-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2022.133847
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2540: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Redox-Active Green Electrode: Plant-Based Betanin Immobilized on Carbon Black for Drift-Free Voltammetric and Potentiometric pH Sensor Applications.

    Meena, Jayaprakash / Santhakumar, Kannappan / Senthil Kumar, Annamalai

    ACS omega

    2023  Volume 8, Issue 48, Page(s) 45787–45800

    Abstract: The development of eco-friendly chemicals and material-based electrode systems with a reduced carbon footprint is a novel initiative for future technological applications. While electrochemical systems based on plant phytochemicals meet the requirements, ...

    Abstract The development of eco-friendly chemicals and material-based electrode systems with a reduced carbon footprint is a novel initiative for future technological applications. While electrochemical systems based on plant phytochemicals meet the requirements, comprehending the fundamental electron-transfer reactions and preparing stable surface-confined redox systems pose significant research challenges. In this study, we have demonstrated an in situ electrochemical reaction-assisted entrapment of redox-active betanin molecular species from native beetroot plants on a carbon black-modified glassy carbon surface (GCE/CB@Betn-Redox, where Betn-Redox stands for redox-active betanin molecular species) in a pH 2.2 KCl-HCl solution. In general, direct access to native plant phytochemicals is a formidable task due to the matrix effect. Isolating the desired phytochemicals necessitates a series of time-consuming chemical separation steps. Unlike previous literature reports on the unstable nature of Betn, GCE/CB@Betn-Redox exhibited a stable and well-defined proton-coupled electron-transfer peak at an apparent electrode potential,
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c06453
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Essential Oil from

    Lin, Wan-Teng / He, Yen-Hua / Lo, Yun-Hsin / Chiang, Yu-Ting / Wang, Sheng-Yang / Bezirganoglu, Ismail / Kumar, K J Senthil

    Plants (Basel, Switzerland)

    2023  Volume 12, Issue 6

    Abstract: Glossogyne ... ...

    Abstract Glossogyne tenuifolia
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants12061241
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Potato protein hydrolysate inhibits RANKL-induced osteoclast development by inhibiting osteoclastogenic genes via the NF-κB/MAPKs signaling pathways.

    Chen, Yi-Ju / He, Yen-Hua / Lo, Yun-Hsin / Yang, Hong-Siang / Abomughaid, Mosleh Mohammad / Kumar, K J Senthil / Lin, Wan-Teng

    Environmental toxicology

    2024  

    Abstract: In recent times, there has been growing attention towards exploring the nutritional and functional aspects of potato protein, along with its diverse applications. In the present study, we examined the anti-osteoclast properties of potato protein ... ...

    Abstract In recent times, there has been growing attention towards exploring the nutritional and functional aspects of potato protein, along with its diverse applications. In the present study, we examined the anti-osteoclast properties of potato protein hydrolysate (PP902) in vitro. Murine macrophages (RAW264.7) were differentiated into osteoclasts by receptor activator of nuclear factor-κB ligand (RANKL), and PP902 was examined for its inhibitory effect. Initially, treatment with PP902 was found to significantly prevent RANKL-induced morphological changes in macrophage cells, as determined by tartrate-resistant acid phosphatase (TRAP) staining analysis. This notion was further supported by F-actin analysis using a confocal microscope. Furthermore, PP902 treatment effectively and dose-dependently down-regulated the expression of RANKL-induced osteoclastogenic marker genes, including TRAP, CTR, RANK, NFATc1, OC-STAMP, and c-Fos. These inhibitory effects were associated with suppressing NF-κB transcriptional activation and subsequent reduced nuclear translocation. The decrease in NF-κB activity resulted from reduced activation of its upstream kinases, including I-κBα and IKKα. Moreover, PP902 significantly inhibited RANKL-induced p38MAPK and ERK1/2 activities. Nevertheless, PP902 treatment prevents RANKL-induced intracellular reactive oxygen species generation via increased HO-1 activity. The combined antioxidant and anti-inflammatory effects of PP902 resulted in significant suppression of osteoclastogenesis, suggesting its potential as an adjuvant therapy for osteoclast-related diseases.
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1463449-1
    ISSN 1522-7278 ; 1520-4081
    ISSN (online) 1522-7278
    ISSN 1520-4081
    DOI 10.1002/tox.24251
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2676: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Antcins from

    Senthil Kumar, K J / Gokila Vani, M / Hsieh, Han-Wen / Lin, Chin-Chung / Wang, Sheng-Yang

    Plants (Basel, Switzerland)

    2021  Volume 10, Issue 8

    Abstract: Antcins are newly identified steroid-like compounds from Taiwan's endemic medicinal ... ...

    Abstract Antcins are newly identified steroid-like compounds from Taiwan's endemic medicinal mushrooms
    Language English
    Publishing date 2021-08-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants10081736
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: An efficient lab-scale soil bioreactor for the removal of chromium (Cr) and arsenic (As) contaminated soil using co-culture

    J, Kamalasini / Gayathri, K. Veena / Kumar, P. Senthil / S., Rajalakshmi

    International Journal of Environmental Analytical Chemistry. 2023 Aug. 09, v. 103, no. 10 p.2318-2337

    2023  

    Abstract: Heavy metal pollution has become a serious global threat in recent times which are mostly caused by anthropogenic activities. Bioremediation is cost-effective and eco-friendly technique. In the present study, bioremediation of the co-metal was performed ... ...

    Abstract Heavy metal pollution has become a serious global threat in recent times which are mostly caused by anthropogenic activities. Bioremediation is cost-effective and eco-friendly technique. In the present study, bioremediation of the co-metal was performed by isolating chromium (Cr) and arsenic (As) resistant bacterial strains and its optimisation of different environmental parameters such as pH, temperature, carbon sources, nitrogen sources and vari+ous concentrations of chromium and arsenic were studied. The isolated co-culture bacterial strains were identified with biochemical and molecular identification using 16s RNA sequencing. Further, a lab-scale soil bioreactor was set up and mineralisation of chromium and arsenic was observed using different heavy metal contaminated soil samples. About 51.1% Chromium was mineralised by the co-culture, 26.7% in cycle 2, 22% in cycle 3 and 34.2% in cycle 4 respectively. The Arsenic mineralisation was 16.7%,23.7%,35.4% and 35.8% at the end of 4 cycles. The final mineralised concentration was analysed by Inductively coupled plasma optical emission Mass spectrometry (ICP-MS) resulting in 29.9 of Chromium and Arsenic 0.083 mg/L respectively. The physico-chemical parameters, such as pH, temperature, TS, TDS, BOD and COD were monitored for the mineralisation study in the soil slurry bioreactor. The study proved that there was effective mineralisation of the co-metals with the cocultures of the isolated bacterial strains from the metal contaminated site.
    Keywords RNA ; analytical chemistry ; arsenic ; bioreactors ; bioremediation ; carbon ; chromium ; coculture ; cost effectiveness ; heavy metals ; mass spectrometry ; mineralization ; nitrogen ; pH ; polluted soils ; pollution ; slurries ; sustainable technology ; temperature ; toxic pollutants ; mineralisation ; soil-bioreactor
    Language English
    Dates of publication 2023-0809
    Size p. 2318-2337.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 120480-4
    ISSN 1029-0397 ; 0306-7319 ; 0092-9085
    ISSN (online) 1029-0397
    ISSN 0306-7319 ; 0092-9085
    DOI 10.1080/03067319.2021.1892664
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 81/708: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Feasibility of magnetic nano adsorbent impregnated with activated carbon from animal bone waste: Application for the chromium (VI) removal.

    Prabu, D / Kumar, P Senthil / Rathi, B Senthil / Sathish, S / Anand, K Vijai / Kumar, J Aravind / Mohammed, Osama B / Silambarasan, P

    Environmental research

    2021  Volume 203, Page(s) 111813

    Abstract: Chromium is the heavy metal which existing in the effluents cause extensive discomfort to the environmental components. Bone waste is widely generated in food processing industries and restaurants. It is now used by switching into activated carbon. By co- ...

    Abstract Chromium is the heavy metal which existing in the effluents cause extensive discomfort to the environmental components. Bone waste is widely generated in food processing industries and restaurants. It is now used by switching into activated carbon. By co-precipitation procedure, the activated carbon is coated with a nano adsorbent. The Fe
    MeSH term(s) Adsorption ; Animals ; Charcoal ; Chromium/analysis ; Feasibility Studies ; Hydrogen-Ion Concentration ; Kinetics ; Magnetic Phenomena ; Water Pollutants, Chemical/analysis ; Water Purification
    Chemical Substances Water Pollutants, Chemical ; Chromium (0R0008Q3JB) ; Charcoal (16291-96-6) ; chromium hexavalent ion (18540-29-9)
    Language English
    Publishing date 2021-08-03
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2021.111813
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 726: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top