LIVIVO - Search results -

Search results

Result 1 - 10 of total 76

Search options

Article ; Online: The complex associations between adiposity, fitness, mental wellbeing and neurocognitive function after exercise: A randomized crossover trial in preadolescent children.

Logan, Nicole E / Occidental, Nicole / Watrous, Jennifer N H / Lloyd, Katherine M / Raine, Lauren B / Kramer, Arthur F / Hillman, Charles H

Progress in brain research

2023 Volume 283, Page(s) 123–165

Abstract: The aim of the present study was to examine the associations of adiposity and fitness on the preadolescent brain's response to acute exercise. In a sample of 58 children (ages 8-10; 19 females), demographic measures of age, sex, IQ, puberty, and ... ...

Abstract	The aim of the present study was to examine the associations of adiposity and fitness on the preadolescent brain's response to acute exercise. In a sample of 58 children (ages 8-10; 19 females), demographic measures of age, sex, IQ, puberty, and socioeconomic status were considered. Children participated in a randomized crossover study, whereby they completed two different interventions; seated rest or treadmill walking, counterbalanced across participants. Associations between adiposity measures (standardized body mass index [BMI-Z], whole body percent fat [%Fat], visceral adipose tissue [VAT]), cardiorespiratory fitness measures (VO
MeSH term(s)	Child ; Female ; Humans ; Adiposity/physiology ; Body Mass Index ; Cross-Over Studies ; Exercise/physiology ; Obesity/psychology ; Male
Language	English
Publishing date	2023-12-19
Publishing country	Netherlands
Document type	Randomized Controlled Trial ; Journal Article
ISSN	1875-7855 ; 0079-6123
ISSN (online)	1875-7855
ISSN	0079-6123
DOI	10.1016/bs.pbr.2023.11.004
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Cross-sectional analysis reveals COVID-19 pandemic community lockdown was linked to dysregulated cortisol and salivary alpha amylase in children.

Lloyd, Katherine M / Gabard-Durnam, Laurel / Beaudry, Kayleigh / De Lisio, Michael / Raine, Lauren B / Bernard-Willis, Ysabeau / Watrous, Jennifer N H / Whitfield-Gabrieli, Susan / Kramer, Arthur F / Hillman, Charles H

Frontiers in public health

2023 Volume 11, Page(s) 1210122

Abstract: The COVID-19 pandemic altered everyday life starting in March 2020. These alterations extended to the lives of children as their normal routines were disrupted by community lockdowns, online learning, limited in-person social contact, increased screen ... ...

Abstract	The COVID-19 pandemic altered everyday life starting in March 2020. These alterations extended to the lives of children as their normal routines were disrupted by community lockdowns, online learning, limited in-person social contact, increased screen time, and reduced physical activity. Considerable research has investigated the physical health impact of COVID-19 infection, but far fewer studies have investigated the physiological impact of stressful pandemic-related changes to daily life, especially in children. The purpose of this study was to leverage an ongoing clinical trial to investigate physiological consequences associated with chronic stress of pandemic community lockdown on children. As a part of the clinical trial, children provided saliva samples. Saliva samples were analyzed for cortisol and salivary alpha amylase (sAA) content. This secondary cross-sectional analysis included 94 preadolescent children located within the Greater Boston, Massachusetts community. Children participated in the study either before, during, or following the pandemic community lockdown to form three groups for comparison. In response to chronic stress caused by the pandemic community lockdown, participants demonstrated dysregulation of fast-acting catecholamine response of the locus-coeruleus-norepinephrine system and slower-acting glucocorticoid response, resulting in an asymmetrical relationship of hypocortisolism (
MeSH term(s)	Child ; Humans ; Salivary alpha-Amylases/analysis ; Hydrocortisone/analysis ; Cross-Sectional Studies ; Pandemics ; COVID-19/epidemiology ; Stress, Psychological ; Communicable Disease Control
Chemical Substances	Salivary alpha-Amylases (EC 3.2.1.1) ; Hydrocortisone (WI4X0X7BPJ)
Language	English
Publishing date	2023-12-15
Publishing country	Switzerland
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1210122
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Aerobic Fitness, B-Vitamins, and Weight Status Are Related to Selective Attention in Children.

Raine, Lauren B / Watrous, Jennifer N H / McDonald, Katherine / Logan, Nicole E / Khan, Naiman A / Kramer, Arthur F / Hillman, Charles H

Nutrients

2021 Volume 14, Issue 1

Abstract: ... these behaviors to cognitive function. B-vitamins are thought to be particularly important in the neural ... regarding the role of B-vitamins during childhood. Given that preadolescent childhood is a critical period ... particularly B-vitamins, and related health factors (e.g., body mass, fitness) on selective attention ...

Abstract	There is an increasing prevalence of poor health behaviors during childhood, particularly in terms of physical activity and nutrition. This trend has occurred alongside a growing body of evidence linking these behaviors to cognitive function. B-vitamins are thought to be particularly important in the neural development that occurs during pregnancy, as well as in healthy cognitive aging. However, much less is known regarding the role of B-vitamins during childhood. Given that preadolescent childhood is a critical period for cognitive development, this study investigated the relationship between specific aspects of nutrition, particularly B-vitamins, and related health factors (e.g., body mass, fitness) on selective attention in children. Children (
MeSH term(s)	Attention/physiology ; Body Mass Index ; Body Weight/physiology ; Child ; Cognition/physiology ; Diet ; Female ; Health Behavior/physiology ; Humans ; Male ; Oxygen Consumption/physiology ; Physical Fitness/physiology ; Reaction Time ; Task Performance and Analysis ; Vitamin B Complex/administration & dosage ; Vitamin B Complex/physiology
Chemical Substances	Vitamin B Complex (12001-76-2)
Language	English
Publishing date	2021-12-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu14010201
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Cross-sectional analysis reveals COVID-19 pandemic community lockdown was linked to dysregulated cortisol and salivary alpha amylase in children

Katherine M. Lloyd / Laurel Gabard-Durnam / Kayleigh Beaudry / Michael De Lisio / Lauren B. Raine / Ysabeau Bernard-Willis / Jennifer N. H. Watrous / Susan Whitfield-Gabrieli / Arthur F. Kramer / Charles H. Hillman

Frontiers in Public Health, Vol

2023 Volume 11

Abstract	The COVID-19 pandemic altered everyday life starting in March 2020. These alterations extended to the lives of children as their normal routines were disrupted by community lockdowns, online learning, limited in-person social contact, increased screen time, and reduced physical activity. Considerable research has investigated the physical health impact of COVID-19 infection, but far fewer studies have investigated the physiological impact of stressful pandemic-related changes to daily life, especially in children. The purpose of this study was to leverage an ongoing clinical trial to investigate physiological consequences associated with chronic stress of pandemic community lockdown on children. As a part of the clinical trial, children provided saliva samples. Saliva samples were analyzed for cortisol and salivary alpha amylase (sAA) content. This secondary cross-sectional analysis included 94 preadolescent children located within the Greater Boston, Massachusetts community. Children participated in the study either before, during, or following the pandemic community lockdown to form three groups for comparison. In response to chronic stress caused by the pandemic community lockdown, participants demonstrated dysregulation of fast-acting catecholamine response of the locus-coeruleus-norepinephrine system and slower-acting glucocorticoid response, resulting in an asymmetrical relationship of hypocortisolism (M = 0.78 ± 0.19 μg/mL, p < 0.001) paired with higher sAA (M = 12.73 ± 4.06 U/mL, p = 0.01). Results suggest that the abrupt COVID-19 disruption to daily life, including the stressful experience of community lockdown, had physiological effects on typically developing children. Further research is required to investigate mental health outcomes of children following the chronic stress of the pandemic community lockdown.
Keywords	children ; cortisol ; salivary alpha amylase ; stress ; dysregulation ; COVID- 19 ; Public aspects of medicine ; RA1-1270
Subject code	360
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Cardiorespiratory fitness levels and body mass index of pre-adolescent children and older adults during the COVID-19 pandemic.

Raine, Lauren B / Erickson, Kirk I / Grove, George / Watrous, Jennifer N H / McDonald, Katherine / Kang, Chaeryon / Jakicic, John M / Forman, Daniel E / Kramer, Arthur F / Burns, Jeffrey M / Vidoni, Eric D / McAuley, Edward / Hillman, Charles H

Frontiers in public health

2023 Volume 10, Page(s) 1052389

Abstract: Introduction: The social and behavioral effects of the COVID-19 pandemic have impacted the health and physiology of most people, including those never diagnosed with COVID-19. While the impact of the pandemic has been felt across the lifespan, its ... ...

Abstract	Introduction: The social and behavioral effects of the COVID-19 pandemic have impacted the health and physiology of most people, including those never diagnosed with COVID-19. While the impact of the pandemic has been felt across the lifespan, its effects on cardiorespiratory fitness (commonly considered a reflection of total body health) of older adults and children may be particularly profound due to social distancing and stay-at-home advisories, as well as the closure of sport facilities and non-essential businesses. The objective of this investigation was to leverage baseline data from two ongoing clinical trials to determine if cardiorespiratory fitness and body mass index were different during COVID-19 relative to before COVID-19 in older adults and children. Methods: Healthy older individuals ( Results: Results revealed that older adults and children tested during COVID-19 had significantly lower cardiorespiratory fitness levels than those tested before COVID-19 shutdowns (older adults: 30% lower; children: 53% lower; Discussion: Results from this investigation indicate that the COVID-19 pandemic, and behavior changes taken to reduce potential exposure, may have led to lower cardiorespiratory fitness levels in older adults and children, as well as higher body mass index. These findings provide relevant public health information as lower cardiorespiratory fitness levels and higher body mass indexes recorded during the pandemic could have far-reaching and protracted health consequences. Public health guidance is needed to encourage physical activity to maintain cardiorespiratory fitness and healthy body composition. Clinical trial registration: Older adults: https://clinicaltrials.gov/ct2/show/NCT02875301, identifier: NCT02875301; Children: https://clinicaltrials.gov/ct2/show/NCT03592238, identifier: NCT03592238.
MeSH term(s)	Humans ; Child ; Adolescent ; Aged ; Body Mass Index ; Cardiorespiratory Fitness ; Physical Fitness/physiology ; Pandemics ; COVID-19/epidemiology
Language	English
Publishing date	2023-01-17
Publishing country	Switzerland
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.1052389
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The role of BMI on cognition following acute physical activity in preadolescent children.

Raine, Lauren B / Kao, Shih-Chun / Drollette, Eric S / Pontifex, Matthew B / Pindus, Dominika / Hunt, Jennifer / Kramer, Arthur F / Hillman, Charles H

Trends in neuroscience and education

2020 Volume 21, Page(s) 100143

Abstract: Background: There is an increasing prevalence of physical inactivity during childhood, concurrent with a rise in obesity rates, which is associated with a variety of health problems. However, the extent to which increased body mass index (BMI) ... ...

Abstract	Background: There is an increasing prevalence of physical inactivity during childhood, concurrent with a rise in obesity rates, which is associated with a variety of health problems. However, the extent to which increased body mass index (BMI) influences acute physical activity (PA) benefits on cognition in childhood remains unknown. The aim of this study was to examine whether BMI influences the effects of acute PA on inhibitory control task performance. Methods: In a sample of 116 children pooled from four prior studies (ages 8-11; 51 females), demographic measures of age, sex, IQ, socioeconomic status, and aerobic fitness were considered along with BMI. Children participated in a counterbalanced, randomized crossover study, whereby they completed two different interventions; 20 minutes of treadmill walking (60-70% heart rate max) and restful reading (non-exercise control). Following each intervention, children performed a modified flanker task that manipulates inhibitory control demands. Correlations were conducted to determine the influence of demographic variables, fitness, and BMI on inhibitory control following each intervention. Subsequent hierarchical regression analyses were performed with significant demographic factors in the first step, aerobic fitness in the second step when significant, and BMI in the final step. Results: Analyses indicated that children exhibited improved task performance (p's ≤ 0.001) and decreased interference (p = 0.04) following the walking intervention compared to the restful reading control condition, indicating greater benefits following acute PA across task condition, with selectively greater benefits for the task condition requiring greater inhibitory control. Regression analyses revealed that greater BMI was related to decreased performance following acute PA (p = 0.001); an association not observed following restful reading (p's ≥ 0.11). These results suggest that BMI negatively influences the effect of acute exercise on performance. Conclusion: Confirming previous studies, these findings indicate beneficial effects of acute PA on a flanker task that modulates inhibitory control requirements, but the effects are significantly greater for task conditions requiring greater amounts of inhibitory control. Further, these beneficial effects of PA appear to be blunted in children with higher BMI. These findings suggest that the acute benefits of PA on cognition may not be fully realized in children with higher BMI.
MeSH term(s)	Body Mass Index ; Child ; Cognition ; Cross-Over Studies ; Exercise ; Female ; Humans ; Physical Fitness
Language	English
Publishing date	2020-10-22
Publishing country	Germany
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural
ZDB-ID	2694503-4
ISSN	2211-9493 ; 2452-0837
ISSN (online)	2211-9493
ISSN	2452-0837
DOI	10.1016/j.tine.2020.100143
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Dynamic changes of adiposity during puberty: life may not be linear.

Hillman, Jennifer B / Biro, Frank M

The Journal of adolescent health : official publication of the Society for Adolescent Medicine

2010 Volume 47, Issue 4, Page(s) 322–323

MeSH term(s)	Adiposity/physiology ; Adolescent ; Adolescent Development/physiology ; Female ; Humans ; Male ; Puberty/physiology ; Sex Factors
Language	English
Publishing date	2010-09-20
Publishing country	United States
Document type	Comment ; Editorial
ZDB-ID	1063374-1
ISSN	1879-1972 ; 1054-139X
ISSN (online)	1879-1972
ISSN	1054-139X
DOI	10.1016/j.jadohealth.2010.06.023
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.B 2453: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Sympathetic Nervous System and Exercise Affects Cognition in Youth (SNEACY): study protocol for a randomized crossover trial.

Raine, Lauren B / McDonald, Katherine / Shigeta, Tatsuya T / Hsieh, Shu-Shih / Hunt, Jennifer / Chiarlitti, Nathan A / Lim, Michelle / Gebhardt, Kristen / Collins, Nina / De Lisio, Michael / Mullen, Sean P / Kramer, Arthur F / Hillman, Charles

Trials

2021 Volume 22, Issue 1, Page(s) 154

Abstract: Background: There is an increasing prevalence of physical inactivity during childhood, which is associated with a variety of health problems. However, the mechanisms by which acute exercise benefits cognition in childhood remains unknown. Here we ... ...

Abstract	Background: There is an increasing prevalence of physical inactivity during childhood, which is associated with a variety of health problems. However, the mechanisms by which acute exercise benefits cognition in childhood remains unknown. Here we describe the protocol for a randomized crossover trial called SNEACY (Sympathetic Nervous System & Exercise Affects Cognition in Youth), a study designed to better understand mechanisms linking acute exercise and cognition in 9-10-year-old healthy, cognitively normal children. Methods: Children from the Greater Boston, MA region will be recruited to participate in this single center study. A randomized crossover design will be utilized, such that participants will act as their own controls, through initial randomization to condition assignment and condition counterbalancing across participants. One hundred three children will participate in three randomized acute interventions: moderate intensity treadmill exercise (20 min, 70-75% of their maximal heart rate), seated rest (20 min), and a Trier Social Stress Test for Children (14 min). These visits will occur on 3 three separate days, approximately 5-8 days apart. Before and after each intervention, children complete a variety of cognitive tasks measuring attentional inhibition while their neuroelectric activity is recorded. Variables of interest include EEG data, accuracy and reaction time, academic achievement, and salivary alpha amylase. Academic achievement is also assessed following interventions. In addition, children provide passive drool samples throughout the interventions to measure various biomarkers that may explain the acute exercise benefit on cognition. Discussion: The results from this study could influence educational and public health recommendations to enhance cognition and learning in pre-adolescent children. Trial registration: ClinicalTrials.gov NCT03592238 . Registered on 19 July 2018.
MeSH term(s)	Adolescent ; Boston ; Child ; Cognition ; Cross-Over Studies ; Exercise ; Humans ; Randomized Controlled Trials as Topic ; Sympathetic Nervous System
Language	English
Publishing date	2021-02-18
Publishing country	England
Document type	Clinical Trial Protocol ; Journal Article
ZDB-ID	2040523-6
ISSN	1745-6215 ; 1468-6694 ; 1468-6708
ISSN (online)	1745-6215 ; 1468-6694
ISSN	1468-6708
DOI	10.1186/s13063-021-05096-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Successes and lessons learned in database development for national multi-site cancer care delivery research trials: the Alliance for Clinical Trials in Oncology experience.

Zahrieh, David / Hillman, Shauna L / Tan, Angelina D / Frank, Jennifer L / Dockter, Travis / Meyers, Bobbi Jo / Cherevko, Cassie L / Peil, Elizabeth S / McCue, Shaylene / Kour, Oudom / Gunn, Heather J / Neuman, Heather B / Chang, George J / Paskett, Electra D / Mandrekar, Sumithra J / Dueck, Amylou C

Trials

2022 Volume 23, Issue 1, Page(s) 645

Abstract: Introduction: Alliance for Clinical Trials in Oncology (Alliance) coordinated trials utilize Medidata Rave® (Rave) as the primary clinical data capture system. A growing number of innovative and complex cancer care delivery research (CCDR) trials are ... ...

Abstract	Introduction: Alliance for Clinical Trials in Oncology (Alliance) coordinated trials utilize Medidata Rave® (Rave) as the primary clinical data capture system. A growing number of innovative and complex cancer care delivery research (CCDR) trials are being conducted within the Alliance with the aims of studying and improving cancer-related care. Because these trials encompass patients, providers, practices, and their interactions, a defining characteristic of CCDR trials is multilevel data collection in pragmatic settings. Consequently, CCDR trials necessitated innovative strategies for database development, centralized data management, and data monitoring in the presence of these real-world multilevel relationships. Having real trial experience in working with community and academic centers, and having recently implemented five CCDR trials in Rave, we are committed to sharing our strategies and lessons learned in implementing such pragmatic trials in oncology. Methods: Five Alliance CCDR trials are used to describe our approach to analyzing the database development needs and the novel strategies applied to overcome the unanticipated challenges we encountered. The strategies applied are organized into 3 categories: multilevel (clinic, clinic stakeholder, patient) enrollment, multilevel quantitative and qualitative data capture, including nontraditional data capture mechanisms being applied, and multilevel data monitoring. Results: A notable lesson learned in each category was (1) to seek long-term solutions when developing the functionality to push patient and non-patient enrollments to their respective Rave study database that affords flexibility if new participant types are later added; (2) to be open to different data collection modalities, particularly if such modalities remove barriers to participation, recognizing that additional resources are needed to develop the infrastructure to exchange data between that modality and Rave; and (3) to facilitate multilevel data monitoring, orient site coordinators to the their trial's multiple study databases, each corresponding to a level in the hierarchy, and remind them to establish the link between patient and non-patient participants in the site-facing NCI web-based enrollment system. Conclusion: Although the challenges due to multilevel data collection in pragmatic settings were surmountable, our shared experience can inform and foster collaborations to collectively build on our past successes and improve on our past failures to address the gaps.
MeSH term(s)	Clinical Trials as Topic ; Data Management ; Databases, Factual ; Health Services Research ; Humans ; Medical Oncology ; Neoplasms/therapy
Language	English
Publishing date	2022-08-09
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2040523-6
ISSN	1745-6215 ; 1468-6694 ; 1745-6215
ISSN (online)	1745-6215
ISSN	1468-6694 ; 1745-6215
DOI	10.1186/s13063-022-06536-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Living with Low Vision: Strategies Supporting Daily Activity.

Smallfield, Stacy / Berger, Sue / Hillman, Brooke / Saltzgaber, Paige / Giger, Jarod / Kaldenberg, Jennifer

Occupational therapy in health care

2017 Volume 31, Issue 4, Page(s) 312–328

Abstract: ... the findings were summarized. Four major themes were identified: (a) device nonuse; (b) sensory strategies and ...

Abstract	The purpose of this research was to describe the strategies that older adults with low vision use to support daily living. A descriptive qualitative study of 10 older adults with low vision was conducted using semistructured, audio-recorded interviews. The data was coded and grouped into categories, and the findings were summarized. Four major themes were identified: (a) device nonuse; (b) sensory strategies and devices; (c) environmental strategies; and (d) resourcefulness. Older adults with low vision try many devices and strategies to find the ones that allow them to participate in meaningful activity within their physical and social environment. These findings support the use of a client-centered, multicomponent, problem-solving approach to low vision rehabilitation to maximize performance of daily activity despite declining vision.
MeSH term(s)	Activities of Daily Living ; Aged ; Aged, 80 and over ; Environment ; Female ; Humans ; Male ; Occupational Therapy ; Problem Solving ; Qualitative Research ; Social Environment ; Surveys and Questionnaires ; Vision, Low
Language	English
Publishing date	2017-10
Publishing country	England
Document type	Journal Article
ZDB-ID	639184-9
ISSN	1541-3098 ; 0738-0577
ISSN (online)	1541-3098
ISSN	0738-0577
DOI	10.1080/07380577.2017.1384969
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 3115: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito