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  1. Book ; Thesis: Myokarditis und dendritische Zellen

    Andreas, Elise / Schulze, Paul Christian / Heidecker, Bettina / Yilmaz, Atilla

    eine Studie zur Charakterisierung und Beeinflussbarkeit der Krankheitsaktivität am Mausmodell (EAM)

    2022  

    Title variant experimentelle Autoimmunmyokarditis
    Institution Friedrich-Schiller-Universität Jena
    Author's details von Elise Andreas
    Keywords Myokarditis ; Dendritische Zelle ; Tiermodell ; Hochschulschrift ; Dissertation
    Subject Doktorarbeit ; Dissertationen ; Herzmuskelentzündung ; Myocarditis
    Language German
    Size IV, 50, xvii Blätter, Illustrationen, Diagramme, 29,5 cm
    Publishing place Jena
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Friedrich-Schiller-Universität Jena, 2022
    Note Tag der Verteidigung: 01.03.2022
    HBZ-ID HT021864494
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Thesis: Genorganisation der Alpha-Untereinheit des Alpha 2 Beta 1 -Integrins

    Yilmaz, Atilla

    (Edition Wissenschaft : Reihe Humanmedizin ; 202)

    1998  

    Author's details Atilla Yilmaz
    Series title Edition Wissenschaft : Reihe Humanmedizin ; 202
    Edition Wissenschaft
    Edition Wissenschaft ; Reihe Humanmedizin
    Collection Edition Wissenschaft
    Edition Wissenschaft ; Reihe Humanmedizin
    Keywords Integrine ; Gen ; Defekt ; Pathomechanismus ; Mikroform
    Subject Erbanlage ; Erbeinheit ; Erbfaktor
    Language German
    Size 92 S.
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Gießen, Univ., Diss., 1998
    Note Mikrofiche-Ausg.: Marburg : Tectum-Verl., 1998. 1 Mikrofiche : 24x. (Edition Wissenschaft : Reihe Humanmedizin ; 202). ISBN 3-8288-0490-X
    HBZ-ID HT009814234
    ISBN 3-8288-0490-X ; 978-3-8288-0490-6
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Association of soluble ST2 Level with 6-month Mortality and/or Recurrent Cardiovascular-Related Hospitalization in Pulmonary Embolism.

    Gunes, Hakan / Gunes, Handan / Dagli, Musa / Kirişçi, Mehmet / Özbek, Meryem / Atilla, Nurhan / Yılmaz, Mehmet Birhan

    Arquivos brasileiros de cardiologia

    2024  Volume 121, Issue 2, Page(s) e20230040

    Abstract: Background: The association of soluble suppression of tumorigenesis-2 (sST2) levels with prognosis in pulmonary embolism (PE) is unknown.: Objective: This study aimed to investigate the relationship between sST2 levels in patients with acute PE and 6- ...

    Title translation Associação do Nível de ST2 Solúvel com Mortalidade em 6 Meses e/ou Hospitalização Recorrente Relacionada a Doenças Cardiovasculares em Embolia Pulmonar.
    Abstract Background: The association of soluble suppression of tumorigenesis-2 (sST2) levels with prognosis in pulmonary embolism (PE) is unknown.
    Objective: This study aimed to investigate the relationship between sST2 levels in patients with acute PE and 6-month mortality and recurrent hospitalizations.
    Methods: This prospective study included 100 patients with acute PE. Patients were classified into two groups according to 6-month mortality and the presence of recurrent Cardiovascular-Related hospitalizations. Two groups were compared. A p-value of 0.05 was considered statistically significant.
    Results: Soluble ST2 levels were significantly higher in the group with mortality and recurrent hospitalizations. (138.6 ng/mL (56.7-236.8) vs. 38 ng/mL (26.3-75.4); p<0.001) The best cut-off threshold for sST2 levels in the prediction of a composite outcome of 6-month mortality and/or recurrent Cardiovascular-Related hospitalization was found to be >89.9 with a specificity of 90.6% and a sensitivity of 65.2%, according to the receiver operating characteristic curve (area under the curve = 0.798; 95% CI, 0.705-0.891; p <0.0001). After adjusting for confounding factors that were either statistically significant in the univariate analysis or for the variables correlated with the sST2 levels, sST2 level (OR = 1.019, 95% CI: 1.009-1.028, p 0.001) and C-reactive protein (CRP ) (OR = 1.010, 95% CI: 1.001-1.021, p = 0.046) continued to be significant predictors of 6-month mortality and/or recurrent Cardiovascular-Related hospitalization in the multiple logistic regression model via backward stepwise method.
    Conclusion: Soluble ST2 level seems to be a biomarker to predict 6-month mortality and/or recurrent Cardiovascular-Related hospitalization in patients with acute PE.
    MeSH term(s) Humans ; Interleukin-1 Receptor-Like 1 Protein ; Prospective Studies ; Prognosis ; Biomarkers ; Pulmonary Embolism ; Acute Disease
    Chemical Substances Interleukin-1 Receptor-Like 1 Protein ; Biomarkers
    Language English
    Publishing date 2024-02-23
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20230040
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  4. Article ; Online: Does subthalamic nucleus deep brain stimulation affect the static balance at different frequencies?

    Oz, Fatma / Yucekeya, Bircan / Huzmeli, Irem / Yilmaz, Atilla

    Neurocirugia (English Edition)

    2023  Volume 34, Issue 2, Page(s) 60–66

    Abstract: Purpose: To investigate the effects of bilateral subthalamic nucleus deep brain stimulation (STN-DBS) with different stimulation frequencies on static balance.: Materials and methods: Twenty patients (15 males and 5 females), aged between 43 and 81 ( ... ...

    Abstract Purpose: To investigate the effects of bilateral subthalamic nucleus deep brain stimulation (STN-DBS) with different stimulation frequencies on static balance.
    Materials and methods: Twenty patients (15 males and 5 females), aged between 43 and 81 (mean: 60.05±7.4) years, who had been diagnosed with idiopathic Parkinson's disease (PD) and undergone STN-DBS surgery were included in the study. Static balance was assessed with TecnoBody Rehabilitation System at four different frequencies: 230, 130, 90 and 60Hz and off-stimulation. Static balance tests were 'stabilometric test, stabilometric compared bipedal closed/opened eye, stabilometric compared mono pedal (right/left foot)'. These tests reported the centre of pressure data 'ellipse area, perimeter, front/back and mediolateral standard deviations'.
    Results: There were no statically differences between the static balance test results at any frequency (p>0.05), but results were found better at 90Hz. Stabilometric compared bipedal opened eye forward-backward standard deviation result was significant between off-stimulation and 130Hz (p=0.04). Different frequency stimulation affected the static balance categories percentage with no statistical significance between off-stimulation and others (all p>0.05).
    Conclusion: This study showed that STN-DBS did not affect the static balance negatively. Low-frequency (LF) stimulation improved the static equilibrium. Posturography systems will give more precise and quantitative results in similar studies with wide frequency ranges.
    MeSH term(s) Male ; Female ; Humans ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Subthalamic Nucleus/physiology ; Deep Brain Stimulation/methods ; Parkinson Disease/therapy
    Language English
    Publishing date 2023-02-06
    Publishing country Spain
    Document type Journal Article
    ISSN 2529-8496
    ISSN (online) 2529-8496
    DOI 10.1016/j.neucie.2022.11.014
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  5. Article ; Online: Kemik Yaşı Tayininde Kullanılan Greulich-Pyle ve Tanner-Whitehouse Yöntemlerinin Karşılaştırılması

    Atilla Kaplan / Hakan Yılmaz

    Adli Tıp Bülteni, Vol 25, Iss

    2020  Volume 1

    Abstract: Amaç: Pediatrik dönemde tıbbi ve adli açıdan önemi nedeniyle kemik yaşı tayini için çekilen sol el bileği grafisini değerlendirmede en çok kullanılan Greulich-Pyle atlası ve Tanner-Whitehouse yöntemlerinin karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: ...

    Abstract Amaç: Pediatrik dönemde tıbbi ve adli açıdan önemi nedeniyle kemik yaşı tayini için çekilen sol el bileği grafisini değerlendirmede en çok kullanılan Greulich-Pyle atlası ve Tanner-Whitehouse yöntemlerinin karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: Bu çalışmada kronolojik yaşları 11-16 arasında değişen 150 kız olgu ve 11-18 arasında değişen 210 erkek olgu incelenmiştir. Toplamda 360 olgu yıllara ve cinsiyete göre 12 gruba ayrılmıştır. Tüm olguların sol el bilek grafileri retrospektif olarak değerlendirilmiştir. Olguların kemik yaşı tespiti GP atlası, TW2 ve TW3 yöntemlerine göre yapılmıştır. TW yönteminde en çok kabul gören RUS skorları kullanılmıştır. Yöntemler ile kronolojik yaş arasında ilişki, fark ve kullanılabilirlik araştırılmıştır. Bulgular: Genelde TW2 yöntemi olguların yaşını daha büyük, TW3 yöntemi ise küçük göstermektedir. Kronolojik yaş ile kemik yaşı arasındaki farklar ise GP yönteminde anlamlı bulunmamış, TW3 yönteminde anlamlı bulunmuştur. Sonuç: Çalışmaya dâhil edilen yaş gruplarında GP atlasının daha kullanılabilir olduğu görülmüştür.
    Keywords kronolojik yaş ; kemik yaşı ; el bilek radyografisi ; Greulich-Pyle atlası ; Tanner Whitehouse yöntemi ; Medicine (General) ; R5-920
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Adli Tıp Uzmanları Derneği
    Document type Article ; Online
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  6. Article ; Online: Kemik Yaşı Tayininde Kullanılan Greulich-Pyle ve Tanner-Whitehouse Yöntemlerinin Karşılaştırılması

    Atilla Kaplan / Hakan Yılmaz

    Adli Tıp Bülteni, Vol 25, Iss

    2020  Volume 1

    Abstract: Amaç: Pediatrik dönemde tıbbi ve adli açıdan önemi nedeniyle kemik yaşı tayini için çekilen sol el bileği grafisini değerlendirmede en çok kullanılan Greulich-Pyle atlası ve Tanner-Whitehouse yöntemlerinin karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: ...

    Abstract Amaç: Pediatrik dönemde tıbbi ve adli açıdan önemi nedeniyle kemik yaşı tayini için çekilen sol el bileği grafisini değerlendirmede en çok kullanılan Greulich-Pyle atlası ve Tanner-Whitehouse yöntemlerinin karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: Bu çalışmada kronolojik yaşları 11-16 arasında değişen 150 kız olgu ve 11-18 arasında değişen 210 erkek olgu incelenmiştir. Toplamda 360 olgu yıllara ve cinsiyete göre 12 gruba ayrılmıştır. Tüm olguların sol el bilek grafileri retrospektif olarak değerlendirilmiştir. Olguların kemik yaşı tespiti GP atlası, TW2 ve TW3 yöntemlerine göre yapılmıştır. TW yönteminde en çok kabul gören RUS skorları kullanılmıştır. Yöntemler ile kronolojik yaş arasında ilişki, fark ve kullanılabilirlik araştırılmıştır. Bulgular: Genelde TW2 yöntemi olguların yaşını daha büyük, TW3 yöntemi ise küçük göstermektedir. Kronolojik yaş ile kemik yaşı arasındaki farklar ise GP yönteminde anlamlı bulunmamış, TW3 yönteminde anlamlı bulunmuştur. Sonuç: Çalışmaya dâhil edilen yaş gruplarında GP atlasının daha kullanılabilir olduğu görülmüştür.
    Keywords kronolojik yaş ; kemik yaşı ; el bilek radyografisi ; Greulich-Pyle atlası ; Tanner Whitehouse yöntemi ; Medicine (General) ; R5-920
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Adli Tıp Uzmanları Derneği
    Document type Article ; Online
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  7. Article ; Online: Comparison of intestinal metaplasia and Helicobacter pylori positivity in patients from different age groups with antral gastritis

    Ugur Kesıcı / Gökmen Öztürk / Atilla Yılmaz / Sevgi Kesici

    Journal of Surgery and Medicine, Vol 5, Iss 3, Pp 226-

    2021  Volume 229

    Abstract: Background/Aim: Gastric carcinoma (GC) is the fourth most common cancer worldwide and the second most common cause of cancer death. Primary prevention for GC includes healthy diet, eradication of Helicobacter pylori (HP), chemoprevention and early ... ...

    Abstract Background/Aim: Gastric carcinoma (GC) is the fourth most common cancer worldwide and the second most common cause of cancer death. Primary prevention for GC includes healthy diet, eradication of Helicobacter pylori (HP), chemoprevention and early diagnosis. For this reason, finding out the HP incidence in patients with suspected antral gastritis in various age groups can lead to forming a treatment strategy to prevent development of GC. The aim of this study is to find out the HP incidence in patients with a proven antral gastritis diagnosis in various age groups and form different treatment strategies. Methods: This study included 1589 patients aged between 15-91 years who underwent diagnostic upper gastrointestinal endoscopy due to complaints of dyspepsia. The demographic characteristics, such as age and sex, and histopathological HP score (HPS) and IM score (IMS) were recorded. The patients were divided into three groups according to age: 15-29 years, 30-64 years, and 65 years and above. Results: In the 15–29-year age group, IM positivity was significantly lower and HP positivity was significantly higher compared to other age groups (P
    Keywords endoscopy ; gastrointestinal system ; intestinal metaplasia ; helicobacter pylori ; Medicine ; R ; Medicine (General) ; R5-920 ; Surgery ; RD1-811
    Subject code 610
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Journal of Surgery and Medicine
    Document type Article ; Online
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  8. Article ; Online: Antimicrobial effect of local anesthetics on Helicobacter pylori

    Mehmet Demirci / Ugur Kesıcı / Atilla Yılmaz

    Journal of Surgery and Medicine, Vol 5, Iss 3, Pp 230-

    2021  Volume 233

    Abstract: Background/Aim: Helicobacter pylori (HP) is a gram-negative bacillus, with a prevalence of 50% throughout the world. HP infection is considered the strongest etiological factor for gastric cancer (GC). Therefore, early diagnosis and treatment of HP can ... ...

    Abstract Background/Aim: Helicobacter pylori (HP) is a gram-negative bacillus, with a prevalence of 50% throughout the world. HP infection is considered the strongest etiological factor for gastric cancer (GC). Therefore, early diagnosis and treatment of HP can be considered as the primary prevention strategy for the development of GC. This study aimed to reveal the antimicrobial effect of commonly used local anesthetics (LAs) on HP. The literature review in English has revealed no study on this subject. Methods: This in vitro laboratory study was conducted in a University laboratory between 25 October 2019 and 1 November 2019. In the study, antimicrobial effect of 1 mL sterile saline, 20 mg/mL lidocaine, 1 mg/mL adrenaline, 10 mg/mL prilocaine, 50 mg/mL bupivacaine, and 20 mg+0.0125 mg/mL lidocaine plus adrenaline against H. pylori strain NCTC 11637 obtained from National Collection of Type Cultures (NCTC) were tested in vitro. The groups were designated as follows: Group C (Control), Group B (Bupivacaine), Group L (Lidocaine), Group A (Adrenaline), Group P (Prilocaine), and Group LA (Lidocaine plus adrenaline). HP strain NCTC 11637 was cultured in Mueller Hinton agar (Oxoid, UK) supplemented with 5% sheep blood plates at 37°C under microaerophilic conditions (5% oxygen, 10% carbon dioxide, and 85% nitrogen gas combination) for 72 hours. Results: Antimicrobial activity was observed in Group L and Group LA. No antimicrobial action against HP was observed in other groups. The comparison of groups in terms of inhibition zone diameters showed that there was a statistically significant inhibiting effect in Group L and Group LA compared to Group C (P=0.002 and P
    Keywords helicobacter pylori ; antimicrobial ; lidocaine ; adrenaline ; bupivacaine ; prilocaine ; Medicine ; R ; Medicine (General) ; R5-920 ; Surgery ; RD1-811
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Journal of Surgery and Medicine
    Document type Article ; Online
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  9. Article ; Online: Comment on: "Managing Diabetic Foot Ulcers: Pharmacotherapy for Wound Healing".

    Colak, Bayram / Orhan, Atilla / Ece, Ilhan / Yormaz, Serdar / Yilmaz, Huseyin / Sahin, Mustafa

    Drugs

    2022  Volume 82, Issue 4, Page(s) 485–486

    MeSH term(s) Diabetes Mellitus ; Diabetic Foot/drug therapy ; Humans ; Wound Healing
    Language English
    Publishing date 2022-02-17
    Publishing country New Zealand
    Document type Letter ; Comment
    ZDB-ID 120316-2
    ISSN 1179-1950 ; 0012-6667
    ISSN (online) 1179-1950
    ISSN 0012-6667
    DOI 10.1007/s40265-022-01673-8
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    Zs.A 762: Show issues Location:
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  10. Article ; Online: Deep brain stimulation for the abernethy malformation related tremor.

    Yalcin, Ahmet / Ceylan, Mustafa / Cakir, Murteza / Ceylan, Onur / Yilmaz, Atilla

    Clinical neurology and neurosurgery

    2022  Volume 224, Page(s) 107554

    Abstract: Deep brain stimulation (DBS) is introduced for the surgical treatment of movement disorders such as Parkinson's disease, tremor, dystonia, and tics. Electrostimulation of the ventral thalamus or subthalamic area has been found effective in different ... ...

    Abstract Deep brain stimulation (DBS) is introduced for the surgical treatment of movement disorders such as Parkinson's disease, tremor, dystonia, and tics. Electrostimulation of the ventral thalamus or subthalamic area has been found effective in different types of tremors that have different etiologies. Abernethy malformation is a rare congenital abnormality characterized by the presence of a congenital extrahepatic portosystemic shunt between the portal vein and systemic circulation. In this report, we present as a case of Abernethy malformation that caused hyperammonemia congenitally and presented as action and resting tremor in the hands and, treated with DBS.
    MeSH term(s) Humans ; Tremor/etiology ; Tremor/therapy ; Deep Brain Stimulation ; Portal Vein/abnormalities ; Parkinson Disease/therapy ; Dystonia/therapy
    Language English
    Publishing date 2022-12-06
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 193107-6
    ISSN 1872-6968 ; 0303-8467
    ISSN (online) 1872-6968
    ISSN 0303-8467
    DOI 10.1016/j.clineuro.2022.107554
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