LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 190

Search options

  1. Article ; Online: A review of acquired blepharoptosis: prevalence, diagnosis, and current treatment options.

    Bacharach, Jason / Lee, Wendy W / Harrison, Andrew R / Freddo, Thomas F

    Eye (London, England)

    2021  Volume 35, Issue 9, Page(s) 2468–2481

    Abstract: Blepharoptosis (ptosis) is among the most common disorders of the upper eyelid encountered in both optometric and ophthalmic practice. The unilateral or bilateral drooping of the upper eyelid that characterises ptosis can affect appearance and impair ... ...

    Abstract Blepharoptosis (ptosis) is among the most common disorders of the upper eyelid encountered in both optometric and ophthalmic practice. The unilateral or bilateral drooping of the upper eyelid that characterises ptosis can affect appearance and impair visual function, both of which can negatively impact quality of life. While there are several known forms of congenital ptosis, acquired ptosis (appearing later in life, due to a variety of causes) is the predominant form of the condition. This review summarises the prevalence, causes, identification, differential diagnosis, and treatment of acquired ptosis. Particular attention is paid to the differential diagnosis of acquired ptosis and emerging treatment options, including surgical and pharmacologic approaches.
    MeSH term(s) Blepharoplasty ; Blepharoptosis/diagnosis ; Blepharoptosis/epidemiology ; Blepharoptosis/etiology ; Eyelids/surgery ; Humans ; Prevalence ; Quality of Life
    Language English
    Publishing date 2021-04-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-021-01547-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 3010: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 603: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Active maintenance of CD8

    Russ, Brendan E / Tsyganov, Kirril / Quon, Sara / Yu, Bingfei / Li, Jasmine / Lee, Jason K C / Olshansky, Moshe / He, Zhaohren / Harrison, Paul F / Barugahare, Adele / See, Michael / Nussing, Simone / Morey, Alison E / Udupa, Vibha A / Bennett, Taylah J / Kallies, Axel / Murre, Cornelis / Collas, Phillipe / Powell, David /
    Goldrath, Ananda W / Turner, Stephen J

    bioRxiv : the preprint server for biology

    2023  

    Abstract: The differentiation of naïve ... ...

    Abstract The differentiation of naïve CD8
    Language English
    Publishing date 2023-02-27
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.02.26.530139
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Active maintenance of CD8

    Russ, Brendan E / Barugahare, Adele / Dakle, Pushkar / Tsyganov, Kirril / Quon, Sara / Yu, Bingfei / Li, Jasmine / Lee, Jason K C / Olshansky, Moshe / He, Zhaohren / Harrison, Paul F / See, Michael / Nussing, Simone / Morey, Alison E / Udupa, Vibha A / Bennett, Taylah J / Kallies, Axel / Murre, Cornelis / Collas, Phillipe /
    Powell, David / Goldrath, Ananda W / Turner, Stephen J

    Cell reports

    2023  Volume 42, Issue 10, Page(s) 113301

    Abstract: The differentiation of naive ... ...

    Abstract The differentiation of naive CD8
    MeSH term(s) CD8-Positive T-Lymphocytes ; Chromatin ; Cell Differentiation ; Transcription Factors/genetics ; Immunologic Memory/genetics
    Chemical Substances Chromatin ; Transcription Factors
    Language English
    Publishing date 2023-10-19
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2023.113301
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: New Strains for Tissue-Specific RNAi Studies in

    Watts, Jason S / Harrison, Henry F / Omi, Shizue / Guenthers, Quentin / Dalelio, James / Pujol, Nathalie / Watts, Jennifer L

    G3 (Bethesda, Md.)

    2020  Volume 10, Issue 11, Page(s) 4167–4176

    Abstract: RNA interference is a powerful tool for dissecting gene function. ... ...

    Abstract RNA interference is a powerful tool for dissecting gene function. In
    MeSH term(s) Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Germ Cells/metabolism ; RNA Interference ; RNA, Double-Stranded ; RNA-Dependent RNA Polymerase
    Chemical Substances Caenorhabditis elegans Proteins ; RNA, Double-Stranded ; RNA-Dependent RNA Polymerase (EC 2.7.7.48) ; RRF-1 protein, C elegans (EC 2.7.7.48)
    Language English
    Publishing date 2020-11-05
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2629978-1
    ISSN 2160-1836 ; 2160-1836
    ISSN (online) 2160-1836
    ISSN 2160-1836
    DOI 10.1534/g3.120.401749
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Tectal plate glioma: lessons learned from a patient with hydrocephalus, Chiari malformation-1 and concomitant aqueductal stenosis.

    Vega, Rafael A / Harrison, Jason F / Scott Graham, R

    Clinical neurology and neurosurgery

    2014  Volume 119, Page(s) 50–53

    MeSH term(s) Adult ; Arnold-Chiari Malformation/diagnosis ; Arnold-Chiari Malformation/etiology ; Arnold-Chiari Malformation/surgery ; Astrocytoma/complications ; Astrocytoma/diagnosis ; Brain Stem Neoplasms/complications ; Brain Stem Neoplasms/diagnosis ; Craniotomy ; Female ; Glioma/complications ; Glioma/diagnosis ; Humans ; Hydrocephalus/diagnosis ; Hydrocephalus/etiology ; Hydrocephalus/surgery ; Magnetic Resonance Imaging ; Tectum Mesencephali/pathology ; Ventriculoperitoneal Shunt
    Language English
    Publishing date 2014-04
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 193107-6
    ISSN 1872-6968 ; 0303-8467
    ISSN (online) 1872-6968
    ISSN 0303-8467
    DOI 10.1016/j.clineuro.2014.01.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui I Zs.53: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Evaluation of biological and economic efficiency of the All Heifer, No Cow beef production system using a system dynamics model based on 6 yr of demonstration herd data.

    Harrison, Meredith A / Sheehan, John J / Seidel, George E / Mooney, Dan F / Rhoades, Ryan D / Ahola, Jason K

    Journal of animal science

    2020  Volume 99, Issue 1

    Abstract: Alternative management strategies with no cows and all heifers may improve biological and economic efficiency of beef production. The All Heifer, No Cow (AHNC) beef production system involves insemination of nulliparous heifers with female sex-selected ... ...

    Abstract Alternative management strategies with no cows and all heifers may improve biological and economic efficiency of beef production. The All Heifer, No Cow (AHNC) beef production system involves insemination of nulliparous heifers with female sex-selected semen (FSS) to produce primarily female calves that are early weaned at 3 mo of age. Dams are finished on a high concentrate diet and harvested before 30 mo of age. The objectives of this research were to: 1) build a dynamic model of an AHNC beef production system to quantify system biological and economic efficiency; 2) compare effects of utilizing FSS vs. conventional semen on biological and economic efficiency; 3) evaluate what-if scenarios to determine the effects on biological and economic efficiency of changing variables ±5%, 10%, 15%, and 20% from initial observed values; and 4) evaluate the effects on biological and economic efficiency of changing variables ±10% from initial observed values. A model was built over a 21-yr horizon using Stella Architect. Biological parameter values in the model were based on the 6 yr of data collected from the management of an AHNC demonstration herd. In the model animal, total digestible nutrients (TDN) intake, hot carcass weight (HCW), and age at harvest were randomized. Feed, animal, and carcass prices included in the model were based on 10 yr of historical U.S. price data. Key response variables were biological and economic efficiency (mean ± SD). Biological efficiency was defined as the ratio of output (kilograms of HCW produced) to input (lifetime kilograms of feed TDN consumed), and economic efficiency was measured using a benefit-cost ratio (BCR) and unit variable cost (UVC). Over 40 simulation runs, the predicted mean biological efficiency was 0.0714 ± 0.0008. Economic efficiency was 0.95 ± 0.02 and US $445.41 ± 0.06 for BCR and UVC, respectively. Biological and economic efficiency was improved in the conventional semen scenario; biological efficiency was 0.0738 ± 0.0008, and BCR and UVC were 0.99 ± 0.04 and US $407.24 ± 0.006, respectively. Under this parameterization and market conditions, the AHNC beef production system failed to achieve profitability under any scenario that was evaluated. However, this review did not account for the potential increased genetic benefit from a decreased generation interval and the reduction in feed energy in comparison to a conventional cow/calf system.
    MeSH term(s) Animal Husbandry ; Animals ; Cattle ; Diet/veterinary ; Eating ; Energy Intake ; Female ; Semen ; Weaning
    Language English
    Publishing date 2020-12-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 390959-1
    ISSN 1525-3163 ; 0021-8812
    ISSN (online) 1525-3163
    ISSN 0021-8812
    DOI 10.1093/jas/skaa405
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1312: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Exome sequencing of hepatocellular carcinoma in lemurs identifies potential cancer drivers: A pilot study.

    Gunady, Ella F / Ware, Kathryn E / Hoskinson Plumlee, Sarah / Devos, Nicolas / Corcoran, David / Prinz, Joseph / Misetic, Hrvoje / Ciccarelli, Francesca D / Harrison, Tara M / Thorne, Jeffrey L / Schopler, Robert / Everitt, Jeffrey I / Eward, William C / Somarelli, Jason A

    Evolution, medicine, and public health

    2022  Volume 10, Issue 1, Page(s) 221–230

    Abstract: Background and objectives: Hepatocellular carcinoma occurs frequently in prosimians, but the cause of these liver cancers in this group is unknown. Characterizing the genetic changes associated with hepatocellular carcinoma in prosimians may point to ... ...

    Abstract Background and objectives: Hepatocellular carcinoma occurs frequently in prosimians, but the cause of these liver cancers in this group is unknown. Characterizing the genetic changes associated with hepatocellular carcinoma in prosimians may point to possible causes, treatments and methods of prevention, aiding conservation efforts that are particularly crucial to the survival of endangered lemurs. Although genomic studies of cancer in non-human primates have been hampered by a lack of tools, recent studies have demonstrated the efficacy of using human exome capture reagents across primates.
    Methodology: In this proof-of-principle study, we applied human exome capture reagents to tumor-normal pairs from five lemurs with hepatocellular carcinoma to characterize the mutational landscape of this disease in lemurs.
    Results: Several genes implicated in human hepatocellular carcinoma, including
    Conclusions and implications: Collectively, this pilot study suggests that human exome capture reagents are a promising tool for genomic studies of cancer in lemurs and other non-human primates.
    Lay summary: Hepatocellular carcinoma occurs frequently in prosimians, but the cause of these liver cancers is unknown. In this proof-of-principle study, we applied human DNA sequencing tools to tumor-normal pairs from five lemurs with hepatocellular carcinoma and compared the lemur mutation profiles to those of human hepatocellular carcinomas.
    Language English
    Publishing date 2022-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2684837-5
    ISSN 2050-6201
    ISSN 2050-6201
    DOI 10.1093/emph/eoac016
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Perspectives on the scientific legacy of J. Philip Grime

    Fridley, Jason D. / Liu, Xiaojuan / Pérez‐Harguindeguy, Natalia / Chapin, F. Stuart, III / Crawley, Mick / De Deyn, Gerlinde / Díaz, Sandra / Grace, James B. / Grubb, Peter / Harrison, Susan / Lavorel, Sandra / Liu, Zhimin / Pierce, Simon / Schmid, Bernhard / Stevens, Carly / Wardle, David A. / Westoby, M.

    Journal of Ecology. 2023 Sept., v. 111, no. 9 p.1814-1831

    2023  

    Abstract: Perhaps as much as any other scientist in the 20th century, J.P. Grime transformed the study of plant ecology and helped shepherd the field toward international prominence as a nexus of ideas related to global environmental change. Editors at the Journal ...

    Abstract Perhaps as much as any other scientist in the 20th century, J.P. Grime transformed the study of plant ecology and helped shepherd the field toward international prominence as a nexus of ideas related to global environmental change. Editors at the Journal of Ecology asked a group of senior plant ecologists to comment on Grime's scientific legacy. This commentary piece includes individual responses of 14 scientists from around the world attesting to Grime's foundational role in plant functional ecology, including his knack for sparking controversy, his unique approach to theory formulation involving clever experiments and standardized trait measurements of large numbers of species, and the continued impact of his work on ecological science and policy.
    Keywords global change ; issues and policy ; plant ecology ; scientists
    Language English
    Dates of publication 2023-09
    Size p. 1814-1831.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note REVIEW
    ZDB-ID 3023-5
    ISSN 0022-0477
    ISSN 0022-0477
    DOI 10.1111/1365-2745.14177
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 2005/720: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Perspectives on the scientific legacy of J. Philip Grime

    Fridley, Jason D. / Liu, Xiaojuan / Pérez-Harguindeguy, Natalia / Chapin, F.S. / Crawley, Mick / de Deyn, Gerlinde / Díaz, Sandra / Grace, James B. / Grubb, Peter / Harrison, Susan / Lavorel, Sandra / Liu, Zhimin / Pierce, Simon / Schmid, Bernhard / Stevens, Carly / Wardle, David A. / Westoby, Mark

    Journal of Ecology

    2023  Volume 111, Issue 9

    Abstract: Perhaps as much as any other scientist in the 20th century, J.P. Grime transformed the study of plant ecology and helped shepherd the field toward international prominence as a nexus of ideas related to global environmental change. Editors at the Journal ...

    Abstract Perhaps as much as any other scientist in the 20th century, J.P. Grime transformed the study of plant ecology and helped shepherd the field toward international prominence as a nexus of ideas related to global environmental change. Editors at the Journal of Ecology asked a group of senior plant ecologists to comment on Grime's scientific legacy. This commentary piece includes individual responses of 14 scientists from around the world attesting to Grime's foundational role in plant functional ecology, including his knack for sparking controversy, his unique approach to theory formulation involving clever experiments and standardized trait measurements of large numbers of species, and the continued impact of his work on ecological science and policy.
    Keywords Grime's triangle ; grasslands ; history of ecology ; plant functional traits ; plant strategy theory
    Language English
    Publishing country nl
    Document type Article ; Online
    ZDB-ID 3023-5
    ISSN 0022-0477
    ISSN 0022-0477
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 2005/720: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1.

    Muturi, Harrison T / Khuder, Saja S / Ghadieh, Hilda E / Esakov, Emily L / Noh, Hyelim / Kang, Heejoon / McInerney, Marcia F / Kim, Jason K / Lee, Abraham D / Najjar, Sonia M

    Cells

    2021  Volume 10, Issue 8

    Abstract: CEACAM1 regulates endothelial barrier integrity. Because insulin signaling in extrahepatic target tissues is regulated by insulin transport through the endothelium, we aimed at investigating the metabolic role of endothelial CEACAM1. To this end, we ... ...

    Abstract CEACAM1 regulates endothelial barrier integrity. Because insulin signaling in extrahepatic target tissues is regulated by insulin transport through the endothelium, we aimed at investigating the metabolic role of endothelial CEACAM1. To this end, we generated endothelial cell-specific
    MeSH term(s) Adipocytes/metabolism ; Animals ; Carcinoembryonic Antigen/genetics ; Carcinoembryonic Antigen/metabolism ; Endothelial Cells/metabolism ; Endothelium, Vascular/metabolism ; Fats/metabolism ; Glucose/metabolism ; Inflammation ; Insulin/metabolism ; Insulin Resistance/genetics ; Liver/cytology ; Liver/metabolism ; Mice ; Mice, Knockout ; NF-kappa B/metabolism ; Nitric Oxide/metabolism ; Signal Transduction
    Chemical Substances Carcinoembryonic Antigen ; Ceacam1 protein, mouse ; Fats ; Insulin ; NF-kappa B ; Nitric Oxide (31C4KY9ESH) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2021-08-14
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells10082093
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top