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  1. Article ; Online: Prostatic Artery Embolization in Patients with Refractory Lower Urinary Tract Symptoms after a Prior Minimally Invasive Surgical Treatment.

    Goyal, Piyush / Varadhan, Ajay K / Jenkins, Kimberly / Hohlastos, Elias / Salem, Riad / Mouli, Samdeep K

    Journal of vascular and interventional radiology : JVIR

    2024  Volume 35, Issue 5, Page(s) 744–750

    Abstract: The purpose of this study was to report on prostatic artery embolization (PAE) outcomes in patients with refractory or recurrent lower urinary tract symptoms (LUTSs) due to benign prostatic hyperplasia (BPH) who had previously undergone a minimally ... ...

    Abstract The purpose of this study was to report on prostatic artery embolization (PAE) outcomes in patients with refractory or recurrent lower urinary tract symptoms (LUTSs) due to benign prostatic hyperplasia (BPH) who had previously undergone a minimally invasive surgical technique (MIST). A single-center retrospective study identified 16 eligible patients. Baseline prostate volume at the time of PAE was 112.9 mL (SD ± 52.7). There were no adverse events throughout the follow-up period. There was significant improvement in International Prostate Symptom Score and quality of life from baseline of 23.5 (SD ± 5.1) and 4.9 (SD ± 0.9), respectively, to the last follow-up of 11.6 (SD ± 7.2) and 2 (SD ± 1.6), respectively. There was nonsignificant improvement in sexual function after PAE compared with baseline after MIST. PAE can be a safe and effective treatment in patients who have undergone prior MIST without negatively impacting erectile or ejaculatory function.
    MeSH term(s) Humans ; Male ; Embolization, Therapeutic/adverse effects ; Prostatic Hyperplasia/therapy ; Prostatic Hyperplasia/surgery ; Prostatic Hyperplasia/physiopathology ; Prostatic Hyperplasia/diagnostic imaging ; Prostatic Hyperplasia/complications ; Lower Urinary Tract Symptoms/etiology ; Lower Urinary Tract Symptoms/therapy ; Lower Urinary Tract Symptoms/physiopathology ; Retrospective Studies ; Aged ; Treatment Outcome ; Prostate/blood supply ; Middle Aged ; Quality of Life ; Minimally Invasive Surgical Procedures ; Time Factors ; Recurrence ; Recovery of Function ; Aged, 80 and over
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1137756-2
    ISSN 1535-7732 ; 1051-0443
    ISSN (online) 1535-7732
    ISSN 1051-0443
    DOI 10.1016/j.jvir.2024.01.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3720: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Identification of Astrovirus in the virome of the upper and lower respiratory tracts of calves with acute signs of bronchopneumonia.

    Gaudino, Maria / Salem, Elias / Ducatez, Mariette F / Meyer, Gilles

    Microbiology spectrum

    2023  Volume 11, Issue 6, Page(s) e0302623

    Abstract: Importance: Astroviruses (AstV) are known suspects of enteric disease in humans and livestock. Recently, AstV have been linked to encephalitis in immunocompromised patients and other animals, such as cattle, minks, and swine. In our study, we also ... ...

    Abstract Importance: Astroviruses (AstV) are known suspects of enteric disease in humans and livestock. Recently, AstV have been linked to encephalitis in immunocompromised patients and other animals, such as cattle, minks, and swine. In our study, we also identified AstV in the respiratory samples of calves with signs of bronchopneumonia, suggesting that their tropism could be even broader. We obtained one bovine AstV (BAstV) complete genome sequence by next-generation sequencing and showed that respiratory and enteric AstV from different species formed a divergent genetic cluster with AstV isolated from encephalitis cases, indicating that tropism might be strain-specific. These data provide further insight into understanding the biology of these understudied pathogens and suggest BAstV as a potential new candidate for bovine respiratory disease.
    MeSH term(s) Animals ; Cattle ; Humans ; Swine ; Astroviridae Infections/veterinary ; Bronchopneumonia/veterinary ; Virome ; Phylogeny ; Astroviridae/genetics ; Cattle Diseases/diagnosis ; Encephalitis ; Respiratory System ; Feces
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.03026-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Rectal adenocarcinoma in the eye: An unexpected destination.

    Lahham, Elias Edward / Alsahouri, Mohammad I / Alsalah, Qusai A / Billan, Salem / Atrash, Fadi

    SAGE open medical case reports

    2024  Volume 12, Page(s) 2050313X241242608

    Abstract: Colorectal cancer ranks third in cancer incidence in the United States, commonly metastasizing to the liver and lungs. Despite its high prevalence, colorectal cancer with intraocular metastasis is exceedingly rare, with only a few cases reported in the ... ...

    Abstract Colorectal cancer ranks third in cancer incidence in the United States, commonly metastasizing to the liver and lungs. Despite its high prevalence, colorectal cancer with intraocular metastasis is exceedingly rare, with only a few cases reported in the literature. This study presents a 58-year-old male, previously treated for rectal adenocarcinoma with liver and lung metastases, who developed choroidal metastasis causing visual impairment. Despite radiotherapy, moderate improvement was observed, and subsequent disease progression led to systemic chemotherapy. Intraocular metastasis, primarily affecting the choroid, is infrequent, often originating from breast and lung cancers. The presented case, originating from primary KRAS wild-type rectal cancer, adds to the limited gastrointestinal-tract-related occurrences. This report underscores the importance of recognizing intraocular metastasis in colorectal cancer, contributing valuable insights for improved understanding and potential guidance for future clinical decisions. Choroidal metastasis carries a poor prognosis, emphasizing the need for tailored management strategies.
    Language English
    Publishing date 2024-03-28
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X241242608
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  4. Article: Prostate Artery Embolization.

    Mouli, Samdeep / Hohlastos, Elias / Salem, Riad

    Seminars in interventional radiology

    2019  Volume 36, Issue 2, Page(s) 142–148

    Language English
    Publishing date 2019-05-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 848341-3
    ISSN 1098-8963 ; 0739-9529
    ISSN (online) 1098-8963
    ISSN 0739-9529
    DOI 10.1055/s-0039-1688431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Se 916: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: A late presentation of inguinoscrotal cutaneous squamous cell carcinoma (cSCC) masquerading as hidradenitis suppurativa-a case report.

    Lahham, Elias Edward / Billan, Salem / Atrash, Fadi / Fararja, Walid

    Journal of surgical case reports

    2023  Volume 2023, Issue 8, Page(s) rjad459

    Abstract: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that affects apocrine gland-bearing skin in intertriginous areas; it is characterized by persistent or recurrent abscesses that culminate in a purulent discharge, sinuses and scarring. ...

    Abstract Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that affects apocrine gland-bearing skin in intertriginous areas; it is characterized by persistent or recurrent abscesses that culminate in a purulent discharge, sinuses and scarring. Although it is a common condition, it is rarely associated with cutaneous squamous cell carcinoma (cSCC). Whereas the female-to-male ratio of HS is 3:1, SCC in HS has a female-to-male ratio of 1:5. In this study, we present a 50-year-old male patient with a late presentation of inguinoscrotal cSCC with extensive ulceration and erythema that was hidden by neglected HS and the presence of underlying human papillomavirus in the affected area. The histomorphologic and immunohistochemical findings support the diagnosis of cSCC. Timely detection is the key to improve prognosis, regular clinical examination and biopsy of any suspicious lesions in high-risk patients is highly recommended.
    Language English
    Publishing date 2023-08-09
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjad459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Spontaneous Coronary Artery Dissection Post Partum.

    Dahdouh, Ziad / Salem, Elias / Mohamed, Tahir

    The Journal of invasive cardiology

    2021  Volume 33, Issue 4, Page(s) E316

    Abstract: A previously healthy 30-year-old woman presented with intensive anterior myocardial infarction at day 6 post partum. Coronary angiogram demonstrated a proximal left anterior descending coronary artery dissection with an intimal flap starting at the ... ...

    Abstract A previously healthy 30-year-old woman presented with intensive anterior myocardial infarction at day 6 post partum. Coronary angiogram demonstrated a proximal left anterior descending coronary artery dissection with an intimal flap starting at the ostial segment and extending to the mid segment separating a large false lumen from a narrow true lumen. Percutaneous coronary intervention was successfully performed using a drug-eluting stent with good angiographic result. Optical coherence tomography showed a widely patent vessel with a crescent hypointense image spanning the stent struts, suggesting a subintimal hematoma. At 1 year, the patient was asymptomatic and imaging showed patency of the stent with no residual wall hematoma.
    MeSH term(s) Adult ; Coronary Angiography ; Coronary Vessel Anomalies/diagnosis ; Coronary Vessel Anomalies/surgery ; Coronary Vessels/diagnostic imaging ; Coronary Vessels/surgery ; Dissection ; Drug-Eluting Stents ; Female ; Humans ; Percutaneous Coronary Intervention ; Tomography, Optical Coherence ; Treatment Outcome
    Language English
    Publishing date 2021-03-30
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1154372-3
    ISSN 1557-2501 ; 1042-3931
    ISSN (online) 1557-2501
    ISSN 1042-3931
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3701: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 272: Show issues
    Zs.MG 31: Show issues

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  7. Article ; Online: Maintenance chemotherapy in advanced and metastatic pancreatic cancer, a narrative review and case series.

    Chehade, Laudy / Elias, Charbel / Mukherji, Deborah / Temraz, Sally / Salem, Ziad / Charafeddine, Maya / Darazi, Monita Al / Shamseddine, Ali

    Asia-Pacific journal of clinical oncology

    2022  Volume 19, Issue 4, Page(s) 419–426

    Abstract: Limited data exist on the management of patients with locally advanced (aPC) or metastatic pancreatic (mPC) cancer who achieve stable disease/response after first-line chemotherapy. In this setting, maintenance therapy is important to minimize toxicity ... ...

    Abstract Limited data exist on the management of patients with locally advanced (aPC) or metastatic pancreatic (mPC) cancer who achieve stable disease/response after first-line chemotherapy. In this setting, maintenance therapy is important to minimize toxicity while preserving survival benefits. The aim of this study is to conduct a narrative review of the evidence available on the topic and present the results of a retrospective case series of patients with aPC or mPC who received maintenance therapy following a good response to induction chemotherapy. Olaparib is the only drug approved for maintenance therapy in patients with metastatic pancreatic cancer and germline Breast Cancer gene mutation. Data from several trials, including the phase II PANOPTIMOX-PRODIGE35 trial, showed clinical benefit from the use of 5-fluorouracil (5-FU) as maintenance. We also conducted a case series including 12 patients who received FOLFIRINOX as induction chemotherapy for aPC or mPC followed by fluorouracil (5-FU) or FOLFIRI maintenance therapy. Median progression-free survival is 22.13 months which is higher than that reported in the literature, which ranges between 5 and 10.6 months. Although further conclusions cannot be drawn because of the small sample size, the results are promising and encourage further exploration of this topic in larger prospective trials.
    MeSH term(s) Humans ; Pancreatic Neoplasms/pathology ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Retrospective Studies ; Maintenance Chemotherapy ; Prospective Studies ; Fluorouracil/therapeutic use ; Leucovorin
    Chemical Substances Fluorouracil (U3P01618RT) ; Leucovorin (Q573I9DVLP)
    Language English
    Publishing date 2022-12-20
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 2187409-8
    ISSN 1743-7563 ; 1743-7555
    ISSN (online) 1743-7563
    ISSN 1743-7555
    DOI 10.1111/ajco.13912
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Massive hemoptysis as a sole presentation of left atrial myxoma.

    Giacaman, Narmeen / Marzouqa, Nizar / Saeed, Elias / Tos, Salem M / Emar, Ahmad / Nassr, Mohammad / Amr, Bajis / Marzouqa, Bisher

    Journal of surgical case reports

    2023  Volume 2023, Issue 5, Page(s) rjad301

    Abstract: Diagnosis of myxoma can be difficult given its variable presentation and while adopting common sense in diagnosing this condition, physicians should also be aware of atypical presentations. Herein we present a 47-year-old heavy smoker presented with ... ...

    Abstract Diagnosis of myxoma can be difficult given its variable presentation and while adopting common sense in diagnosing this condition, physicians should also be aware of atypical presentations. Herein we present a 47-year-old heavy smoker presented with massive blood-stained expectoration. He was later diagnosed with cardiac myxoma and managed accordingly.
    Language English
    Publishing date 2023-05-29
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjad301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Prostate Artery Embolization

    Mouli, Samdeep / Hohlastos, Elias / Salem, Riad

    Seminars in Interventional Radiology

    (Management of Complications in IR)

    2019  Volume 36, Issue 02, Page(s) 142–148

    Series title Management of Complications in IR
    Language English
    Publishing date 2019-05-22
    Publisher Thieme Medical Publishers
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 848341-3
    ISSN 1098-8963 ; 0739-9529
    ISSN (online) 1098-8963
    ISSN 0739-9529
    DOI 10.1055/s-0039-1688431
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

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  10. Article ; Online: Video-assisted reflection: improving OSCE feedback.

    Mitchell, Oliver / Cotton, Natalia / Leedham-Green, Kathleen / Elias, Salem / Bartholomew, Brent

    The clinical teacher

    2021  Volume 18, Issue 4, Page(s) 409–416

    Abstract: Background: Objective Structured Clinical Examinations (OSCEs) are commonly used to provide feedback to students on their performance in formative examinations. However, students are often unable to act independently on the feedback they receive. This ... ...

    Abstract Background: Objective Structured Clinical Examinations (OSCEs) are commonly used to provide feedback to students on their performance in formative examinations. However, students are often unable to act independently on the feedback they receive. This study explored how the use of video-assisted reflection in OSCEs can enhance students' ability to reflect and engage in sustainable feedback.
    Methods: Twenty-one students undertaking a mock-final OSCE consented to have one of their examination stations filmed. Participants completed a series of reflective forms immediately after the OSCE, after verbal feedback from an examiner and finally, after watching the video of their own performance. Students were asked to predict their overall grade as well as list areas for improvement. Pearson r correlations examined the relationship between the examiners' grades and the candidates' self-predicted grades. Wilcoxon signed-rank tests were used to compare the length of reflections at each stage. Semi-structured interviews were conducted to explore students' beliefs on self-efficacy and how the video-assisted reflection altered their ability to act on feedback.
    Results: The students' ability to self-assess and gauge their own performance improved significantly after undertaking the video-assisted reflection (p < 0.01). Furthermore, video-assisted reflection significantly increased the length of the student's reflections. In interviews, participants described multiple ways in which the video-assisted reflection improved their confidence and ability to act on feedback, highlighting a clear enhancement in self-efficacy.
    Discussion: Video-assisted reflection of recorded OSCE stations represents an effective approach to increase student self-efficacy and subsequently improve engagement in sustainable feedback practice.
    MeSH term(s) Clinical Competence ; Educational Measurement ; Feedback ; Humans ; Physical Examination ; Students, Medical
    Language English
    Publishing date 2021-05-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2151518-9
    ISSN 1743-498X ; 1743-4971
    ISSN (online) 1743-498X
    ISSN 1743-4971
    DOI 10.1111/tct.13354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6678: Show issues Location:
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