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  1. Book ; Online ; Conference proceedings ; E-Book: Advances in medical physics and healthcare engineering

    Mukherjee, Moumita

    proceedings of AMPHE 2020

    (Lecture Notes in Bioengineering)

    2021  

    Author's details Moumita Mukherjee [and four others] editors
    Series title Lecture Notes in Bioengineering
    Keywords Biomedical engineering ; Biophysics
    Subject code 610.28
    Language English
    Size 1 online resource (586 pages)
    Publisher Springer
    Publishing place Singapore
    Document type Book ; Online ; Conference proceedings ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-336-915-9 ; 981-336-914-0 ; 978-981-336-915-3 ; 978-981-336-914-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Silicon Carbide

    Mukherjee, Moumita

    Materials, Processing and Applications in Electronic Devices

    2011  

    Keywords Circuits & components
    Language English
    Size 1 electronic resource (560 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030644803
    ISBN 9789535144199 ; 9535144197
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Advanced Microwave and Millimeter Wave Technologies : Semiconductor Devices Circuits and Systems

    Mukherjee, Moumita

    2010  

    Keywords Robotics ; Microwave technology
    Size 1 electronic resource (654 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021044991
    ISBN 9789535158851 ; 9535158856
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: First-principles Calculations Reveal Frictional Advantage for C

    Mukherjee, Moumita / Mandal, Sucharita / Datta, Ayan

    Chemistry, an Asian journal

    2023  Volume 18, Issue 17, Page(s) e202300525

    Abstract: Friction at the atomic scale is determined for three different carbon nitride structures namely ... ...

    Abstract Friction at the atomic scale is determined for three different carbon nitride structures namely C
    Language English
    Publishing date 2023-08-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202300525
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Identification of Key Deregulated RNA-Binding Proteins in Pancreatic Cancer by Meta-Analysis and Prediction of Their Role as Modulators of Oncogenesis

    Moumita Mukherjee / Srikanta Goswami

    Frontiers in Cell and Developmental Biology, Vol

    2021  Volume 9

    Abstract: RNA-binding proteins (RBPs) play a significant role in multiple cellular processes with their deregulations strongly associated with cancer. However, there are not adequate evidences regarding global alteration and functions of RBPs in pancreatic cancer, ...

    Abstract RNA-binding proteins (RBPs) play a significant role in multiple cellular processes with their deregulations strongly associated with cancer. However, there are not adequate evidences regarding global alteration and functions of RBPs in pancreatic cancer, interrogated in a systematic manner. In this study, we have prepared an exhaustive list of RBPs from multiple sources, downloaded gene expression microarray data from a total of 241 pancreatic tumors and 124 normal pancreatic tissues, performed a meta-analysis, and obtained differentially expressed RBPs (DE-RBPs) using the Limma package of R Bioconductor. The results were validated in microarray datasets and the Cancer Genome Atlas (TCGA) RNA sequencing dataset for pancreatic adenocarcinoma (PAAD). Pathway enrichment analysis was performed using DE-RBPs, and we also constructed the protein–protein interaction (PPI) network to detect key modules and hub-RBPs. Coding and noncoding targets for top altered and hub RBPs were identified, and altered pathways modulated by these targets were also investigated. Our meta-analysis identified 45 upregulated and 15 downregulated RBPs as differentially expressed in pancreatic cancer, and pathway enrichment analysis demonstrated their important contribution in tumor development. As a result of PPI network analysis, 26 hub RBPs were detected and coding and noncoding targets for all these RBPs were categorized. Functional exploration characterized the pathways related to epithelial-to-mesenchymal transition (EMT), cell migration, and metastasis to emerge as major pathways interfered by the targets of these RBPs. Our study identified a unique meta-signature of 26 hub-RBPs to primarily modulate pancreatic tumor cell migration and metastasis in pancreatic cancer. IGF2BP3, ISG20, NIP7, PRDX1, RCC2, RUVBL1, SNRPD1, PAIP2B, and SIDT2 were found to play the most prominent role in the regulation of EMT in the process. The findings not only contribute to understand the biology of RBPs in pancreatic cancer but also to evaluate their ...
    Keywords RNA-binding protein ; pancreatic cancer ; meta-analysis ; epithelial-to-mesenchymal transition ; target RNAs ; Biology (General) ; QH301-705.5
    Subject code 500
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Synergistic Augmentation of Beta-Lactams: Exploring Quinoline-Derived Amphipathic Small Molecules as Antimicrobial Potentiators against Methicillin-Resistant

    Ghosh, Surojit / Sen, Samya / Jash, Moumita / Ghosh, Satyajit / Jana, Aniket / Roy, Rajsekhar / Mukherjee, Nabanita / Mukherjee, Dipro / Sarkar, Jayita / Ghosh, Surajit

    ACS infectious diseases

    2024  Volume 10, Issue 4, Page(s) 1267–1285

    Abstract: The escalation of bacterial resistance against existing therapeutic antimicrobials has reached a critical peak, leading to the rapid emergence of multidrug-resistant strains. Stringent pathways in novel drug discovery hinder our progress in this survival ...

    Abstract The escalation of bacterial resistance against existing therapeutic antimicrobials has reached a critical peak, leading to the rapid emergence of multidrug-resistant strains. Stringent pathways in novel drug discovery hinder our progress in this survival race. A promising approach to combat emerging antibiotic resistance involves enhancing conventional ineffective antimicrobials using low-toxicity small molecule adjuvants. Recent research interest lies in weak membrane-perturbing agents with unique cyclic hydrophobic components, addressing a significant gap in antimicrobial drug exploration. Our study demonstrates that quinoline-based amphipathic small molecules, SG-B-52 and SG-B-22, significantly reduce MICs of selected beta-lactam antibiotics (ampicillin and amoxicillin) against lethal methicillin-resistant
    MeSH term(s) Methicillin-Resistant Staphylococcus aureus ; beta-Lactams/pharmacology ; beta-Lactams/therapeutic use ; Drug Synergism ; Anti-Infective Agents/pharmacology ; Quinolines/pharmacology
    Chemical Substances beta-Lactams ; Anti-Infective Agents ; Quinolines
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Journal Article
    ISSN 2373-8227
    ISSN (online) 2373-8227
    DOI 10.1021/acsinfecdis.3c00696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Identification of Key Deregulated RNA-Binding Proteins in Pancreatic Cancer by Meta-Analysis and Prediction of Their Role as Modulators of Oncogenesis.

    Mukherjee, Moumita / Goswami, Srikanta

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 713852

    Abstract: RNA-binding proteins (RBPs) play a significant role in multiple cellular processes with their deregulations strongly associated with cancer. However, there are not adequate evidences regarding global alteration and functions of RBPs in pancreatic cancer, ...

    Abstract RNA-binding proteins (RBPs) play a significant role in multiple cellular processes with their deregulations strongly associated with cancer. However, there are not adequate evidences regarding global alteration and functions of RBPs in pancreatic cancer, interrogated in a systematic manner. In this study, we have prepared an exhaustive list of RBPs from multiple sources, downloaded gene expression microarray data from a total of 241 pancreatic tumors and 124 normal pancreatic tissues, performed a meta-analysis, and obtained differentially expressed RBPs (DE-RBPs) using the Limma package of R Bioconductor. The results were validated in microarray datasets and the Cancer Genome Atlas (TCGA) RNA sequencing dataset for pancreatic adenocarcinoma (PAAD). Pathway enrichment analysis was performed using DE-RBPs, and we also constructed the protein-protein interaction (PPI) network to detect key modules and hub-RBPs. Coding and noncoding targets for top altered and hub RBPs were identified, and altered pathways modulated by these targets were also investigated. Our meta-analysis identified 45 upregulated and 15 downregulated RBPs as differentially expressed in pancreatic cancer, and pathway enrichment analysis demonstrated their important contribution in tumor development. As a result of PPI network analysis, 26 hub RBPs were detected and coding and noncoding targets for all these RBPs were categorized. Functional exploration characterized the pathways related to epithelial-to-mesenchymal transition (EMT), cell migration, and metastasis to emerge as major pathways interfered by the targets of these RBPs. Our study identified a unique meta-signature of 26 hub-RBPs to primarily modulate pancreatic tumor cell migration and metastasis in pancreatic cancer. IGF2BP3, ISG20, NIP7, PRDX1, RCC2, RUVBL1, SNRPD1, PAIP2B, and SIDT2 were found to play the most prominent role in the regulation of EMT in the process. The findings not only contribute to understand the biology of RBPs in pancreatic cancer but also to evaluate their candidature as possible therapeutic targets.
    Language English
    Publishing date 2021-11-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.713852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effectiveness of metal and metal oxide nanoparticles against bacterial biofilms: Perspectives and limitations.

    Mukherjee, Dipro / Sil, Moumita / Goswami, Arunava / Lahiri, Dibyajit / Nag, Moupriya

    Journal of basic microbiology

    2023  Volume 63, Issue 9, Page(s) 971–985

    Abstract: In the last few years, there has been a necessary demand in the pharmaceutical industries for finding a treatment against biofilms formed by different bacterial species. We are aware of the fact that classical processes, which are already there for the ... ...

    Abstract In the last few years, there has been a necessary demand in the pharmaceutical industries for finding a treatment against biofilms formed by different bacterial species. We are aware of the fact that classical processes, which are already there for the removal of bacterial biofilms gives a very low efficiency and consequently antimicrobial resistance makes it even worse. To cope up with the cited problems, scientists from the past few years are inclining toward various types of nanoparticle based treatment procedures as a pharmaceutical agent against bacterial biofilms. Nanoparticles are known for their extremely efficient antimicrobial properties. The current review gives a description of different types of metal oxide nanoparticles and their antibiofilm properties. It also shows a comparative analysis of the nanoparticles and depicts the efficiency rates of biofilm degradation in each of them. It explains the mechanism of the nanoparticles through which the disintegration of bacterial biofilm is carried out. Lastly, the review throws light upon the limitations of different nanoparticles, their safety issues, the mutagenicity, genotoxicity concerns, and toxicity hazards caused by them.
    MeSH term(s) Oxides/pharmacology ; Anti-Bacterial Agents/pharmacology ; Metal Nanoparticles ; Nanoparticles ; Bacteria ; Anti-Infective Agents ; Biofilms ; Metals/pharmacology
    Chemical Substances Oxides ; Anti-Bacterial Agents ; Anti-Infective Agents ; Metals
    Language English
    Publishing date 2023-05-08
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 632513-0
    ISSN 1521-4028 ; 0233-111X
    ISSN (online) 1521-4028
    ISSN 0233-111X
    DOI 10.1002/jobm.202300013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 824: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Investigating the interference of single nucleotide polymorphisms with miRNA mediated gene regulation in pancreatic ductal adenocarcinoma: An in silico approach

    Mukherjee, Moumita / Ghosh, Satyajit / Goswami, Srikanta

    Gene. 2022 Apr. 20, v. 819

    2022  

    Abstract: Pancreatic ductal adenocarcinoma (PDAC) has a strong genetic component and single nucleotide polymorphisms (SNPs) in key genes have been found to modulate the susceptibility of the individuals to the disease. SNPs in 3′-UTR of the target genes or in ... ...

    Abstract Pancreatic ductal adenocarcinoma (PDAC) has a strong genetic component and single nucleotide polymorphisms (SNPs) in key genes have been found to modulate the susceptibility of the individuals to the disease. SNPs in 3′-UTR of the target genes or in miRNA seed region has gained much importance as this may lead to impairment of miRNA-mRNA interaction. Not much information about this phenomenon is available with respect to PDAC and we wanted to predict such SNPs which could affect miRNA function in the disease using bioinformatics tools. After identifying the deregulated miRNAs and genes in PDAC, we determined how many of those altered genes are among experimentally validated targets of those miRNAs. Subsequently, SNPs which could alter these miRNA-mRNA interactions were detected using multiple webtools following high stringent conditions. Disease relevance of the SNPs were also evaluated. We identified a total of 2492 experimentally validated target genes for 303 miRNAs deregulated in PDAC. Our meta-analysis from 363 PDAC patients and 162 control individuals resulted in a set of differentially expressed genes in pancreatic cancer, which was further compared with the miRNA target genes to get targets differentially expressed in pancreatic cancer. We further detected SNPs either in ‘seed’ region of miRNAs or ‘seed-match’ sequence of mRNAs either having disruption or creation of miRNA binding site, correlated the expression for each miRNA-SNP-mRNA interaction. Selected SNPs were found to be in LD with important GWAS identified SNPs. Our study, hereby, explores the probable effects of SNPs on miRNA-target mRNA interactions. Through stringent analytical methods, we have identified 3 common variants and 13other rare variants possibly interfering with miRNA mediated gene regulation in PDAC.
    Keywords adenocarcinoma ; bioinformatics ; computer simulation ; gene expression regulation ; genes ; meta-analysis ; microRNA ; pancreatic neoplasms
    Language English
    Dates of publication 2022-0420
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 391792-7
    ISSN 1879-0038 ; 0378-1119
    ISSN (online) 1879-0038
    ISSN 0378-1119
    DOI 10.1016/j.gene.2022.146259
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 79/715: Show issues

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  10. Article ; Online: Effectiveness of metal and metal oxide nanoparticles against bacterial biofilms: Perspectives and limitations

    Mukherjee, Dipro / Sil, Moumita / Goswami, Arunava / Lahiri, Dibyajit / Nag, Moupriya

    Journal of Basic Microbiology. 2023 Sept., v. 63, no. 9 p.971-985

    2023  

    Abstract: In the last few years, there has been a necessary demand in the pharmaceutical industries for finding a treatment against biofilms formed by different bacterial species. We are aware of the fact that classical processes, which are already there for the ... ...

    Abstract In the last few years, there has been a necessary demand in the pharmaceutical industries for finding a treatment against biofilms formed by different bacterial species. We are aware of the fact that classical processes, which are already there for the removal of bacterial biofilms gives a very low efficiency and consequently antimicrobial resistance makes it even worse. To cope up with the cited problems, scientists from the past few years are inclining toward various types of nanoparticle based treatment procedures as a pharmaceutical agent against bacterial biofilms. Nanoparticles are known for their extremely efficient antimicrobial properties. The current review gives a description of different types of metal oxide nanoparticles and their antibiofilm properties. It also shows a comparative analysis of the nanoparticles and depicts the efficiency rates of biofilm degradation in each of them. It explains the mechanism of the nanoparticles through which the disintegration of bacterial biofilm is carried out. Lastly, the review throws light upon the limitations of different nanoparticles, their safety issues, the mutagenicity, genotoxicity concerns, and toxicity hazards caused by them.
    Keywords antibiotic resistance ; biofilm ; genotoxicity ; microbiology ; mutagenicity ; nanoparticles
    Language English
    Dates of publication 2023-09
    Size p. 971-985.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note REVIEW
    ZDB-ID 632513-0
    ISSN 1521-4028 ; 0233-111X
    ISSN (online) 1521-4028
    ISSN 0233-111X
    DOI 10.1002/jobm.202300013
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 824: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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