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  1. Article ; Online: Burkholderia cepacia outbreak in immunocompetent children in a tertiary hospital in Turkey

    Ceren Cetin / Ugurgul Arslan

    Asian Pacific Journal of Tropical Medicine, Vol 15, Iss 8, Pp 374-

    A case series

    2022  Volume 378

    Abstract: Objective: To report an outbreak of Burkholderia (B.) cepacia related to contaminated surface cleaner in the pediatric ward of a tertiary hospital in Turkey. Methods: This study retrospectively reported the outbreak occurred between January 16, 2018 and ... ...

    Abstract Objective: To report an outbreak of Burkholderia (B.) cepacia related to contaminated surface cleaner in the pediatric ward of a tertiary hospital in Turkey. Methods: This study retrospectively reported the outbreak occurred between January 16, 2018 and January 23, 2018. Twelve immunocompetent patients who developed a bloodstream infection a few days after the hospitalization and who were positive for B. cepacia were included. Environmental samples were collected from various areas in the hospital to find the source of the outbreak. Results: All patients had clinical and biochemical evidence of sepsis. None of the patients had an underlying disease or had a central venous catheter as a risk factor. B. cepacia was isolated from the samples taken from the surface cleaners. The antibiotic susceptibilities of B. cepacia isolates were identical in the surface cleaners with the isolates from the patients’ blood cultures. The outbreak was controlled after removing the surface cleaners from use. None of the infected patients died during the outbreak. Conclusions: Nosocomial B. cepacia outbreak may occur in immunocompetent children as well. Rapid identification of the outbreak, defining the source and taking appropriate measures to control the outbreak are the key points in the management.
    Keywords burkholderia cepacia ; bacteremia ; immunocompetent ; outbreak ; infection control ; Arctic medicine. Tropical medicine ; RC955-962
    Subject code 610
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Global surveillance, travel, and trade during a pandemic

    Çetin, Ceren / Kara, Ateş

    Turkish journal of medical sciences

    2020  Volume 50, Issue SI-1, Page(s) 527–533

    Abstract: Pandemics have had very important consequences in human history. Lots of people lost their lives and countries have been intensively affected in terms of socioeconomic problems. Unfortunately, avoidance of pandemics and limiting the spread are still ... ...

    Abstract Pandemics have had very important consequences in human history. Lots of people lost their lives and countries have been intensively affected in terms of socioeconomic problems. Unfortunately, avoidance of pandemics and limiting the spread are still currently not always possible. Maybe the most important factor for this is the increasing frequency of traveling. Increasing airline traveling rate also increases the rate of spread. Global organizations like the World Health Organization and United Nations are trying to play a supreme role over the countries. Pandemics do not have borders; therefore, efforts should be given globally, definition of pandemic should be established as soon as possible, and protective measures should be shared with countries. If these are not done, severe health consequences and serious economic problems are inevitable.
    MeSH term(s) Global Health ; Humans ; Influenza, Human/epidemiology ; Pandemics ; Population Surveillance/methods ; Seasons ; Travel/trends
    Keywords covid19
    Language English
    Publishing date 2020-04-21
    Publishing country Turkey
    Document type Journal Article ; Review
    ZDB-ID 1183461-4
    ISSN 1303-6165 ; 1300-0144
    ISSN (online) 1303-6165
    ISSN 1300-0144
    DOI 10.3906/sag-2004-175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Intraocular Lens Elongation Technique with Haptic Modification for Sulcus Implantation.

    Baykara, Mehmet / Uçan Gündüz, Gamze / Çetin Efe, Ayşe / Yurttaş, Ceren

    Turkish journal of ophthalmology

    2022  Volume 52, Issue 4, Page(s) 223–227

    Abstract: Objectives: To define a haptic modification technique to increase the overall length of the intraocular lens (IOL) and evaluate the postoperative outcomes of patients in whom this technique was applied.: Materials and methods: The preoperative and ... ...

    Abstract Objectives: To define a haptic modification technique to increase the overall length of the intraocular lens (IOL) and evaluate the postoperative outcomes of patients in whom this technique was applied.
    Materials and methods: The preoperative and postoperative characteristics of patients who underwent modified IOL implantation into the sulcus between May 2019 and December 2019 were evaluated. Modified Sensar AR40e lenses with hydrophobic acrylic optic and polymethylmethacrylate haptics were implanted to all eyes. Before implanting the IOL, the haptics were grasped with two toothless forceps and bent to elongate the total diameter of the IOL from 13.0 mm to 14.5 mm.
    Results: The study included 11 eyes of 11 patients who underwent modified three-piece IOL implantation into the sulcus due to insufficient capsular support. The mean age of the patients was 53.9±12.2 years. The mean axial length was 24.13±1.93 mm. Sulcus implantation was required due to aphakia in 9 eyes and IOL dislocation in 2 eyes. No haptic breakage occurred during the IOL modification technique or implantation. The mean preoperative best corrected visual acuity (BCVA) was 0.88±1.1 logMAR, while postoperative BCVA was 0.28±0.30 logMAR. No IOL dislocation or decentration was observed during 6-month postoperative follow-up.
    Conclusion: The larger diameter lenses obtained with this inexpensive and easily applicable technique may allow a more stable sulcus implantation in eyes with inadequate capsular support.
    MeSH term(s) Adult ; Aged ; Humans ; Lens Implantation, Intraocular/adverse effects ; Lens Implantation, Intraocular/methods ; Lenses, Intraocular ; Middle Aged ; Postoperative Complications/etiology ; Visual Acuity
    Language English
    Publishing date 2022-08-25
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2586160-8
    ISSN 2149-8709 ; 2147-2661 ; 2149-8709 ; 1300-0659
    ISSN (online) 2149-8709
    ISSN 2147-2661 ; 2149-8709 ; 1300-0659
    DOI 10.4274/tjo.galenos.2021.38275
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Intraocular Lens Elongation Technique with Haptic Modification for Sulcus Implantation

    Mehmet Baykara / Gamze Uçan Gündüz / Ayşe Çetin Efe / Ceren Yurttaş

    Türk Oftalmoloji Dergisi, Vol 52, Iss 4, Pp 223-

    2022  Volume 227

    Abstract: Objectives:To define a haptic modification technique to increase the overall length of the intraocular lens (IOL) and evaluate the postoperative outcomes of patients in whom this technique was applied.Materials and Methods:The preoperative and ... ...

    Abstract Objectives:To define a haptic modification technique to increase the overall length of the intraocular lens (IOL) and evaluate the postoperative outcomes of patients in whom this technique was applied.Materials and Methods:The preoperative and postoperative characteristics of patients who underwent modified IOL implantation into the sulcus between May 2019 and December 2019 were evaluated. Modified Sensar AR40e lenses with hydrophobic acrylic optic and polymethylmethacrylate haptics were implanted to all eyes. Before implanting the IOL, the haptics were grasped with two toothless forceps and bent to elongate the total diameter of the IOL from 13.0 mm to 14.5 mm.Results:The study included 11 eyes of 11 patients who underwent modified three-piece IOL implantation into the sulcus due to insufficient capsular support. The mean age of the patients was 53.9±12.2 years. The mean axial length was 24.13±1.93 mm. Sulcus implantation was required due to aphakia in 9 eyes and IOL dislocation in 2 eyes. No haptic breakage occurred during the IOL modification technique or implantation. The mean preoperative best corrected visual acuity (BCVA) was 0.88±1.1 logMAR, while postoperative BCVA was 0.28±0.30 logMAR. No IOL dislocation or decentration was observed during 6-month postoperative follow-up.Conclusion:The larger diameter lenses obtained with this inexpensive and easily applicable technique may allow a more stable sulcus implantation in eyes with inadequate capsular support.
    Keywords aphakia ; intraocular lens implantation ; lens dislocation ; ciliary sulcus ; Medicine ; R ; Ophthalmology ; RE1-994
    Subject code 600
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher Galenos Yayinevi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Effects of noopept on ocular, pancreatic and renal histopathology in streptozotocin induced prepubertal diabetic rats.

    Gurbuz, Perihan / Duzova, Halil / Taslidere, Asli Cetin / Gul, Cemile Ceren

    Biotechnic & histochemistry : official publication of the Biological Stain Commission

    2023  Volume 98, Issue 5, Page(s) 314–325

    Abstract: Diabetes mellitus (DM) is a chronic disease at all ages including childhood and puberty. Failure to treat DM can cause retinopathy, nephropathy and neuropathy. Endocrine and metabolic changes during the pubertal period complicate management of DM. ... ...

    Abstract Diabetes mellitus (DM) is a chronic disease at all ages including childhood and puberty. Failure to treat DM can cause retinopathy, nephropathy and neuropathy. Endocrine and metabolic changes during the pubertal period complicate management of DM. Noopept is a cognitive enhancer that exhibits antidiabetic properties. We investigated the effect of noopept on the histopathology of the cornea, retina, kidney and pancreas in pubertal diabetic rats. We allocated 60 prepubertal male rats randomly into six groups of 10: untreated control (C), DM control (DC), noopept control (NC), DM + noopept (D + N), DM + insulin (D + I) and DM + insulin + noopept (D + I + N). DM was induced by streptozotocin in the DC, D + N, D + I and D + I + N groups. Noopept was administered to the NC, D + N and D + I + N groups; insulin was administered to the D + I and D + I + N groups for 14 days. On day 18 of the experiment, animals were sacrificed and eyes, kidneys and pancreata were excised for histological investigation. Renal tubule diameter and corneal and retinal thickness were increased significantly in DC groups compared to the control group. The D + I, D + N and D + I + N groups exhibited fewer DM induced pathological changes than the DC group. The D + I + N group exhibited no significant differences in renal tubule diameter and corneal and retinal thickness compared to the DC group. Our findings suggest that noopept is protective against DM end organ complications in streptozotocin induced diabetic pubertal rats.
    MeSH term(s) Rats ; Male ; Animals ; Diabetes Mellitus, Experimental/metabolism ; Streptozocin/pharmacology ; Sexual Maturation ; Kidney ; Insulin/pharmacology ; Insulin/metabolism ; Pancreas
    Chemical Substances ethyl phenylacetyl-Pro-Gly (4QBJ98683M) ; Streptozocin (5W494URQ81) ; Insulin
    Language English
    Publishing date 2023-03-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1069349-x
    ISSN 1473-7760 ; 1052-0295
    ISSN (online) 1473-7760
    ISSN 1052-0295
    DOI 10.1080/10520295.2023.2187460
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Evaluation of chronotype and sleep quality in infertile population and comparison with fertile population: a cross-sectional study.

    Özçelik, Ceren / Varlı, Bulut / Gökçe, Ali / Takmaz, Taha / Çetin, Çağlar / Özcan, Pınar

    Journal of psychosomatic obstetrics and gynaecology

    2022  Volume 44, Issue 1, Page(s) 2148523

    Abstract: Purpose: Infertility is a stressful condition for couples and can affect patients' circadian rhythm and sleep quality. The goal of this study is to assess differences in chronotype and sleep quality between infertile and fertile people.: Methods: A ... ...

    Abstract Purpose: Infertility is a stressful condition for couples and can affect patients' circadian rhythm and sleep quality. The goal of this study is to assess differences in chronotype and sleep quality between infertile and fertile people.
    Methods: A cross-sectional study was conducted. The infertile patient population consisted study group. Primiparous patients without any known gynecological disease who presented for routine cervical cancer screening follow-up were included in the control group. The Turkish version of the Morningness-Eveningness Questionnaire (MEQ) and Pittsburg Sleep Quality Index (PSQI) scores were evaluated between groups.
    Results: A total of 227 patients were assessed. There were 110 patients in the study (infertile) group and 117 patients in the control (fertile) group. The evening chronotype proportion (23.6
    Conclusions: In this study, we found significantly worse sleep quality, and more evening chronotype in the patients with infertility.
    MeSH term(s) Female ; Humans ; Cross-Sectional Studies ; Chronotype ; Early Detection of Cancer ; Sleep Quality ; Uterine Cervical Neoplasms
    Language English
    Publishing date 2022-12-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 604816-x
    ISSN 1743-8942 ; 0167-482X
    ISSN (online) 1743-8942
    ISSN 0167-482X
    DOI 10.1080/0167482X.2022.2148523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Non-invasive Screening of Metabolic Associated Fatty Liver Disease and Affecting Factors in Primary Care.

    Balci, Idil Ceren / Haciagaoglu, Nazli / Oner, Can / Cetin, Huseyin / Simsek, Engin Ersin

    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

    2023  Volume 33, Issue 4, Page(s) 390–395

    Abstract: Objective: To identify the presence of MAFLD (metabolic associated fatty liver disease) with some non-invasive screening methods and the factors affecting in patients with metabolic dysfunction.: Study design: A cross-sectional study. Place and ... ...

    Abstract Objective: To identify the presence of MAFLD (metabolic associated fatty liver disease) with some non-invasive screening methods and the factors affecting in patients with metabolic dysfunction.
    Study design: A cross-sectional study. Place and Duration of the Study: University of Health Sciences, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkiye, from March to June 2021.
    Methodology: This study included 233 participants with metabolic disease over the age of 18 who applied to family medicine clinics. The participants' sociodemographic data, chronic disease status, biochemical parameters, waist circumference, weight, height, body mass index, and presence of steatosis by ultrasonography were recorded. The risk of developing hepatic fibrosis and steatosis was calculated with the non-alcoholic fatty liver disease liver fat score (NAFLD-LFS), hepatic steatosis index (HSI), fatty liver index (FLI), fibrosis-4 index (FIB-4), NAFLD fibrosis score (NAFLD-FS), and aspartate aminotransaminase to platelet ratio index (APRI). The conclusions were evaluated with SPSS.
    Results: According to the diagnostic criteria, MAFLD was detected in 58.4% of the participants. Statistically significant difference was found between FLI, HSI, NAFLD-LFS and MAFLD (p<0.001). According to the steatosis index risk groups of the participants, 64.4% - 89.7% were found to be high-risk. Steatosis was confirmed by ultrasonography in 63.6% - 77.8% of those at high-risk for index steatosis. The statistically significant difference was found between hypertension, diabetes mellitus, hyperlipidemia, metabolic syndrome, obesity, and MAFLD (p=0.039, p<0.001, p<0.001, p<0.001, and p=0.011, respectively).
    Conclusion: Using non-invasive screening methods for steatosis can be clinically useful in detecting patients at risk for steatosis, and these methods are applicable in predicting MAFLD.
    Key words: NAFLD, Fatty liver ındex, Hepatic steatosis index, MAFLD, Steatosis.
    MeSH term(s) Humans ; Adult ; Middle Aged ; Non-alcoholic Fatty Liver Disease/diagnostic imaging ; Non-alcoholic Fatty Liver Disease/epidemiology ; Cross-Sectional Studies ; Risk Factors ; Liver Cirrhosis/diagnostic imaging ; Liver Cirrhosis/complications ; Primary Health Care
    Language English
    Publishing date 2023-05-16
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 2276646-7
    ISSN 1681-7168 ; 1022-386X
    ISSN (online) 1681-7168
    ISSN 1022-386X
    DOI 10.29271/jcpsp.2023.04.390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The Efficacy of Chest Computed Tomography in Pediatric Patients With Suspected COVID-19.

    Rona, Günay / Voyvoda, Nuray / Arifoğlu, Meral / Karaaslan, Ayşe / Çetin, Ceren

    Journal of computer assisted tomography

    2021  Volume 45, Issue 2, Page(s) 337–341

    Abstract: Objective: The aim of the study was to investigate chest computed tomography (CT) findings and the value of CT in the diagnosis in children with suspected coronavirus disease 2019 (COVID-19).: Materials and methods: Chest CT images of pediatric ... ...

    Abstract Objective: The aim of the study was to investigate chest computed tomography (CT) findings and the value of CT in the diagnosis in children with suspected coronavirus disease 2019 (COVID-19).
    Materials and methods: Chest CT images of pediatric patients with suspected COVID-19 were retrospectively evaluated. Computed tomography findings were divided into 3 groups: normal, consistent, and inconsistent with COVID-19. The sensitivity and specificity of CT were calculated by reference to reverse transcriptase polymerase chain reaction.
    Results: The study included patients with a mean age of 11.1 years (1 month-17 years). Of the patients, 43 (40.19%) had normal CT, 34 (31.77%) had CT findings consistent with COVID-19, and 30 (28.04%) had CT findings inconsistent with COVID-19. The sensitivity, specificity, positive predictive value, and negative predictive value of CT were 47.92%, 81.36%, 67.65%, and 65.75%, respectively.
    Conclusions: Because the sensitivity of CT in the pediatric age group is low, it should be used cautiously for the evaluation of COVID-19 in the pediatric age group.
    MeSH term(s) Adolescent ; COVID-19/diagnostic imaging ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Lung/diagnostic imaging ; Male ; Reproducibility of Results ; SARS-CoV-2 ; Sensitivity and Specificity ; Tomography, X-Ray Computed/methods
    Keywords covid19
    Language English
    Publishing date 2021-03-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80392-3
    ISSN 1532-3145 ; 0363-8715
    ISSN (online) 1532-3145
    ISSN 0363-8715
    DOI 10.1097/RCT.0000000000001127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Global surveillance, travel, and trade during a pandemic

    Çetin, Ceren / Kara, Ates

    Turk J Med Sci

    Abstract: Pandemics have had very important consequences in human history. Lots of people lost their lives and countries have been intensively affected in terms of socioeconomic problems. Unfortunately, avoidance of pandemics and limiting the spread are still ... ...

    Abstract Pandemics have had very important consequences in human history. Lots of people lost their lives and countries have been intensively affected in terms of socioeconomic problems. Unfortunately, avoidance of pandemics and limiting the spread are still currently not always possible. Maybe the most important factor for this is the increasing frequency of traveling. Increasing airline traveling rate also increases the rate of spread. Global organizations like the World Health Organization and United Nations are trying to play a supreme role over the countries. Pandemics do not have borders; therefore, efforts should be given globally, definition of pandemic should be established as soon as possible, and protective measures should be shared with countries. If these are not done, severe health consequences and serious economic problems are inevitable.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #71830
    Database COVID19

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