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Article ; Online: Samples in randomized clinical trials with interim analysis.

Saaibi Meléndez, Michelle / Botero-Rodríguez, Felipe / Rincón Rodríguez, Carlos Javier

Revista peruana de medicina experimental y salud publica

2024 Volume 40, Issue 2, Page(s) 220–228

Abstract: Objectives.: This article introduces randomized clinical trials and basic concepts of statistical inference. We present methods for calculating the sample size by outcome type and the hypothesis to be tested, together with the code in the R programming ... ...

Title translation	La muestra en ensayos clínicos aleatorizados con análisis interino.
Abstract	Objectives.: This article introduces randomized clinical trials and basic concepts of statistical inference. We present methods for calculating the sample size by outcome type and the hypothesis to be tested, together with the code in the R programming language. We describe four methods for adjusting the original sample size for interim analyses. We sought to introduce these topics in a simple and concrete way, considering the mathematical expressions that support the results and their implementation in available statistical programs; therefore, bringing health students closer to statistics and the use of statistical programs, which are aspects that are rarely considered during their training.
MeSH term(s)	Humans ; Randomized Controlled Trials as Topic ; Sample Size ; Research Design
Language	English
Publishing date	2024-01-15
Publishing country	Peru
Document type	Journal Article
ZDB-ID	2120092-0
ISSN	1726-4642 ; 1726-4642
ISSN (online)	1726-4642
ISSN	1726-4642
DOI	10.17843/rpmesp.2023.402.12217
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Corruption and its relation to prevalence and death due to noncommunicable diseases and risk factors: a global perspective.

Botero-Rodríguez, Felipe / Pantoja-Ruiz, Camila / Rosselli, Diego

Revista panamericana de salud publica = Pan American journal of public health

2022 Volume 46, Page(s) e10

Abstract: Objective: To describe the relation between corruption indicators and statistics on noncommunicable diseases and their risk factors by continent.: Methods: An ecological study was conducted to examine the relation of the GINI coefficient, the Country ...

Abstract	Objective: To describe the relation between corruption indicators and statistics on noncommunicable diseases and their risk factors by continent. Methods: An ecological study was conducted to examine the relation of the GINI coefficient, the Country Policy and Institutional Assessment (CPIA), and the Corruption Perception Index (CPI) with noncommunicable diseases, using the Spearman's rank correlation test. Results: There is a moderate and positive correlation between Corruption Perception Index and cause of death due to noncommunicable diseases and risk factors for these diseases ( Conclusions: This study indicates a correlation between corruption and noncommunicable diseases and their risk factors. This suggests that the high prevalence of noncommunicable diseases and risk factors could be related with political practices that negatively impact the population. Further research should study the weight of these associations, to take action on the way corruption is impacting on the health of societies.
Language	English
Publishing date	2022-03-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	1376934-0
ISSN	1680-5348 ; 1020-4989
ISSN (online)	1680-5348
ISSN	1020-4989
DOI	10.26633/RPSP.2022.10
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Article ; Online: Corruption and its relation to prevalence and death due to noncommunicable diseases and risk factors

Felipe Botero-Rodríguez / Camila Pantoja-Ruiz / Diego Rosselli

Revista Panamericana de Salud Pública, Vol 46, Iss 10, Pp 1-

a global perspective

2022 Volume 9

Abstract: Objective. To describe the relation between corruption indicators and statistics on noncommunicable diseases and their risk factors by continent. Methods. An ecological study was conducted to examine the relation of the GINI coefficient, the Country ... ...

Abstract	Objective. To describe the relation between corruption indicators and statistics on noncommunicable diseases and their risk factors by continent. Methods. An ecological study was conducted to examine the relation of the GINI coefficient, the Country Policy and Institutional Assessment (CPIA), and the Corruption Perception Index (CPI) with noncommunicable diseases, using the Spearmans rank correlation test. Results. There is a moderate and positive correlation between Corruption Perception Index and cause of death due to noncommunicable diseases and risk factors for these diseases (r = 0.532), prevalence of schizophrenia (r = 0.526), bipolar disorder (r = 0.520), and eating disorders (r = 0.677). There is a moderate negative association between the GINI index and cause of death due to noncommunicable diseases (r = 0.571) and smoking prevalence (r = 0.502), and between the Corruption Perception Index and mortality caused by cardiovascular diseases, cancer, diabetes, or chronic respiratory diseases between the exact ages of 30 and 70 years (r = 0.577) and malnutrition prevalence (r = 0.602). Conclusions. This study indicates a correlation between corruption and noncommunicable diseases and their risk factors. This suggests that the high prevalence of noncommunicable diseases and risk factors could be related with political practices that negatively impact the population. Further research should study the weight of these associations, to take action on the way corruption is impacting on the health of societies.
Keywords	corruption ; noncommunicable diseases ; chronic disease ; global health strategies ; delivery of health care ; politics ; Medicine ; R ; Arctic medicine. Tropical medicine ; RC955-962 ; Public aspects of medicine ; RA1-1270
Subject code	610
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	Pan American Health Organization
Document type	Article ; Online
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Article ; Online: Pandemic's glossary: The ABC of coronavirus concepts

Botero-Rodríguez, Felipe / Franco, Oscar / Carlos

Biomedica : revista del Instituto Nacional de Salud

2020 Volume 40, Issue Supl. 2, Page(s) 16–26

Title translation	Glosario para una pandemia: el ABC de los conceptos sobre el coronavirus.
MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Keywords	covid19
Language	Spanish
Publishing date	2020-10-30
Publishing country	Colombia
Document type	Dictionary
ZDB-ID	2059952-3
ISSN	2590-7379 ; 2590-7379
ISSN (online)	2590-7379
ISSN	2590-7379
DOI	10.7705/biomedica.5605
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Article: Glosario para una pandemia: el ABC de los conceptos sobre el coronavirus./ Glosario para una pandemia: el ABC de los conceptos sobre el coronavirus./ Pandemic's glossary: The ABC of coronavirus concepts

Botero-Rodríguez, Felipe / Franco, Oscar

Biomedica

Abstract: Currently, the world is facing the pandemic generated by SARS-CoV-2. There are no no pharmacological measures for the prevention or treatment of this infection and, so far, it has caused more than 4´880.000 confirmed cases and 322.000 deaths. The ... ...

Abstract	Currently, the world is facing the pandemic generated by SARS-CoV-2. There are no no pharmacological measures for the prevention or treatment of this infection and, so far, it has caused more than 4´880.000 confirmed cases and 322.000 deaths. The different strategies for the control of the disease that have been proposed involve the participation of different actors. Such participation, guided by legal guidelines based on public health measures, include containment, mitigation, physical isolation, and quarantine. As this is a populationbased problem, information plays a primary role; however, the many new terms hat have arisen and their misuse confuse and, therefore, misinform thus limiting citizen participation. For this reason, we conducted a review of the terms used in epidemics and pandemics of infectious diseases, particularly COVID-19. We considered and differentiated the relevant terms to facilitate the understanding of pathogen's behavior and epidemic and pandemic cycles, as well as the criteria for public health decision-making for the general public. This glossary should facilitate the use of the terms and standardize the information.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #914756
Database	COVID19

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Article ; Online: Neuropsychiatric Symptoms in Patients with Neurocognitive Disorder and Their Performance Between Mild and Major Stages.

Botero-Rodríguez, Felipe / Córdoba Sastoque, Ana Melisa / Santacruz Escudero, José Manuel / Santamaría-García, Hernando

Journal of Alzheimer's disease : JAD

2021 Volume 85, Issue 4, Page(s) 1735–1744

Abstract: Background: The neuropsychiatric symptoms (NPS) in patients with neurocognitive disorders (NCD) increases the risk of exhibiting significant cognitive and functional decline. However, to the best of our knowledge, few studies have evaluated to what ... ...

Abstract	Background: The neuropsychiatric symptoms (NPS) in patients with neurocognitive disorders (NCD) increases the risk of exhibiting significant cognitive and functional decline. However, to the best of our knowledge, few studies have evaluated to what extent the presence of chronic and early NPS impacts cognition and functionality in patients with minor or major stages of NCD. Objective: We aimed to assess the interplay between early and chronic NPS and cognitive and functional presentation of patients with mild and major forms of NCD. Methods: We used two NPS tools tracking early and late NPS and assessed to what extent they determine cognitive and functional outcomes in patients with mild and major forms of NCD. Results: We found an inverse relationship between the presence of NPS, as measured by the Neuropsychiatric Inventory and Mild Behavioral Impairment Checklist (MBI-C), and cognitive and functional variables in major forms of NCD. In contrast, the minor stage of NCD was associated with increased MBI-C scores. Conclusion: Our results revealed that NPS are associated with cognitive and functional outcomes in mild and chronic forms of NCD. Crucially our results suggest that NPS could be considered as a pathological marker of the clinical course of dementia. Additionally, our study calls to study early and late forms of NPS as both impact cognition and functionality of NCD.
MeSH term(s)	Aged ; Checklist ; Cognitive Dysfunction/complications ; Dementia/diagnosis ; Female ; Humans ; Male ; Neurocognitive Disorders/diagnosis ; Neuropsychological Tests/statistics & numerical data ; Symptom Assessment
Language	English
Publishing date	2021-12-27
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1440127-7
ISSN	1875-8908 ; 1387-2877
ISSN (online)	1875-8908
ISSN	1387-2877
DOI	10.3233/JAD-215283
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Article ; Online: Glosario para una pandemia

Felipe Botero-Rodríguez / Oscar Franco / Carlos Gómez Restrepo

Biomédica: revista del Instituto Nacional de Salud, Vol 40, Iss Supl. 2, Pp 16-

el ABC de los conceptos sobre el coronavirus

2020 Volume 26

Abstract: Actualmente, el mundo se enfrenta a la pandemia generada por el SARS-CoV-2, infección para la cual no hay medidas farmacológicas de prevención ni tratamiento. Hasta el momento, ha dejado más de 4´880.000 casos confirmados y 322.000 muertes. Se han ... ...

Abstract	Actualmente, el mundo se enfrenta a la pandemia generada por el SARS-CoV-2, infección para la cual no hay medidas farmacológicas de prevención ni tratamiento. Hasta el momento, ha dejado más de 4´880.000 casos confirmados y 322.000 muertes. Se han propuesto diferentes estrategias para el control de la enfermedad que implican la participación de diferentes sectores de la sociedad con acciones guiadas por lineamientos jurídicos y basados en medidas de salud pública, entre ellas, la contención, la mitigación, el aislamiento físico y la cuarentena. Dado que se trata de una situación de dimensión poblacional, la información tiene un papel fundamental; sin embargo, la proliferación de términos nuevos, muchas veces usados erróneamente, causa confusión y desinformacion y, en consecuencia, limitan la participacion ciudana. En ese contexto, en el presente documento se hizo una revisión de los términos utilizados en epidemias y pandemias de enfermedades infecciosas, con énfasis en la COVID-19, para facilitar al público general la comprensión de los términos relevantes sobre el comportamiento de los agentes patógenos y de su ciclo epidémico y pandémico, así como los criterios para la adopción de las decisiones pertinentes en salud pública. Se aspira a que el glosario resultante ayude al uso correcto de los términos y a homogenizar la información.
Keywords	pandemia ; infecciones por coronavirus ; virus del sras ; prevención y mitigación ; descriptores de las ciencias de la salud ; Medicine ; R ; Arctic medicine. Tropical medicine ; RC955-962
Language	English
Publishing date	2020-10-01T00:00:00Z
Publisher	Instituto Nacional de Salud
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Pandemic's glossary

Botero-Rodríguez, Felipe / Franco, Oscar / Gómez Restrepo, Carlos

Biomedica; Vol. 40 No. Supl.; 16-26 ; Biomédica; Vol. 40 Núm. Supl. 2 (2020): SARS-CoV-2 y COVID-19; 16-26 ; 2590-7379 ; 0120-4157

The ABC of coronavirus concepts ; Glosario para una pandemia: el ABC de los conceptos sobre el coronavirus

2020 Volume 2, Issue : SARS-CoV-2 y COVID-19

Abstract	Currently, the world is facing the pandemic generated by SARS-CoV-2. There are no no pharmacological measures for the prevention or treatment of this infection and, so far, it has caused more than 4´880.000 confirmed cases and 322.000 deaths. The different strategies for the control of the disease that have been proposed involve the participation of different actors. Such participation, guided by legal guidelines based on public health measures, include containment, mitigation, physical isolation, and quarantine. As this is a populationbased problem, information plays a primary role; however, the many new terms hat have arisen and their misuse confuse and, therefore, misinform thus limiting citizen participation.For this reason, we conducted a review of the terms used in epidemics and pandemics of infectious diseases, particularly COVID-19. We considered and differentiated the relevant terms to facilitate the understanding of pathogen’s behavior and epidemic and pandemic cycles, as well as the criteria for public health decision-making for the general public. This glossary should facilitate the use of the terms and standardize the information. Actualmente, el mundo se enfrenta a la pandemia generada por el SARS-CoV-2, infección para la cual no hay medidas farmacológicas de prevención ni tratamiento. Hasta el momento, ha dejado más de 4´880.000 casos confirmados y 322.000 muertes. Se han propuesto diferentes estrategias para el control de la enfermedad que implican la participación de diferentes sectores de la sociedad con acciones guiadas por lineamientos jurídicos y basados en medidas de salud pública, entre ellas, la contención, la mitigación, el aislamiento físico y la cuarentena. Dado que se trata de una situación de dimensión poblacional, la información tiene un papel fundamental; sin embargo, la proliferación de términos nuevos, muchas veces usados erróneamente, causa confusión y desinformacion y, en consecuencia, limitan la participacion ciudana.En ese contexto, en el presente documento se hizo una revisión de los términos utilizados en epidemias y pandemias de enfermedades infecciosas, con énfasis en la COVID-19, para facilitar al público general la comprensión de los términos relevantes sobre el comportamiento de los agentes patógenos y de su ciclo epidémico y pandémico, así como los criterios para la adopción de las decisiones pertinentes en salud pública. Se aspira a que el glosario resultante ayude al uso correcto de los términos y a homogenizar la información.
Keywords	Pandemics ; coronavirus infections ; SARS virus ; prevention and mitigation ; medical subject headings ; pandemia ; infecciones por coronavirus ; virus del SRAS ; prevención y mitigación ; descriptores de las ciencias de la salud ; covid19
Language	Spanish
Publishing date	2020-10-30
Publisher	Instituto Nacional de Salud
Publishing country	co
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Analysis of perceptions and emotional repercussions in Twitter users in Colombia during the COVID-19 pandemic.

Botero-Rodríguez, Felipe / Mosquera-Quiñónez, Melizza / Martínez Torres, Liz Mariana / Bolívar-Moná, Santiago / Jovel T, Gabriela / Vargas C, Laura / Franco, Oscar H / Gómez-Restrepo, Carlos

Revista Colombiana de psiquiatria (English ed.)

2023 Volume 52, Issue 3, Page(s) 206–212

Abstract: Introduction: The COVID-19 pandemic has negatively impacted mental health. Up to a quarter of the population has reported mental health disorders. This has been studied mainly from a nosological perspective, according to diagnostic criteria. ... ...

Abstract	Introduction: The COVID-19 pandemic has negatively impacted mental health. Up to a quarter of the population has reported mental health disorders. This has been studied mainly from a nosological perspective, according to diagnostic criteria. Nevertheless, we did not find studies that have explored the daily expressions of the population. Our objective was to evaluate the perceptions of the COVID-19 pandemic and its repercussions on the emotional well-being of the Colombian population. Methods: We performed a Twitter metrics and trend analysis. Initially, in the trend analysis, we calculated the average duration in hours of the 20 most popular trending topics of the day in Colombia and we grouped them into trends related to COVID-19 and unrelated trends. Subsequently, we identified dates of events associated with the pandemic relevant to the country, and they were related to the behaviour of the trends studied. Additionally, we did an exploratory analysis of these, selected the tweets with the greatest reach and categorised them in an inductive way to analyse them qualitatively. Results: Issues not related to COVID-19 were more far-reaching than those related to coronavirus. However, a rise in these issues was seen on some dates consistent with important events in Colombia. We found expressions of approval and disapproval, solidarity and accusation. Inductively, we identified categories of informative tweets, humour, fear, stigma and discrimination, politics and entities, citizen complaints, and self-care and optimism. Conclusions: The impact of the COVID-19 pandemic generates different reactions in the population, which increasingly have more tools to express themselves and know the opinions of others. Social networks play a fundamental role in the communication of the population, so this content could serve as a public health surveillance tool and a useful and accessible means of communication in the management of health crises.
MeSH term(s)	Humans ; COVID-19/psychology ; Pandemics ; Colombia ; SARS-CoV-2 ; Social Media
Language	Spanish
Publishing date	2023-10-20
Publishing country	Spain
Document type	Journal Article
ISSN	2530-3120
ISSN (online)	2530-3120
DOI	10.1016/j.rcpeng.2021.05.008
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Article ; Online: The Dark Side of the Moon: Global challenges in the distribution of vaccines and implementation of vaccination plans against COVID-19.

Mesa-Vieira, Cristina / Botero-Rodríguez, Felipe / Padilla-Muñoz, Andrea / Franco, Oscar H / Gómez-Restrepo, Carlos

Maturitas

2021 Volume 149, Page(s) 37–39

Language	English
Publishing date	2021-05-26
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	80460-5
ISSN	1873-4111 ; 0378-5122
ISSN (online)	1873-4111
ISSN	0378-5122
DOI	10.1016/j.maturitas.2021.05.003
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