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  1. Article ; Online: Frost-resistant nanocellulose-based organohydrogel with high mechanical strength and transparency.

    Yan, Zifei / Jiang, Shan / Xi, Jianfeng / Ye, Wenjie / Meng, Liucheng / Xiao, Huining / Wu, Weibing

    Journal of colloid and interface science

    2024  Volume 661, Page(s) 879–887

    Abstract: ... method in a new binary solvent system of N, N-dimethylformamide and water (DMF-H ...

    Abstract Improving mechanical strength and frost-resistance is an important research direction in the field of hydrogel materials. Herein, using bacterial nanocellulose (BC) as a reinforcing agent and polyvinyl alcohol (PVA) as a polymer matrix, a frost-resistant organohydrogel was constructed via the freezing-thawing method in a new binary solvent system of N, N-dimethylformamide and water (DMF-H
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2024.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Smoothness-Adaptive Dynamic Pricing with Nonparametric Demand Learning

    Ye, Zeqi / Jiang, Hansheng

    2023  

    Abstract: We study the dynamic pricing problem where the demand function is nonparametric and H\"older smooth ... and we focus on adaptivity to the unknown H\"older smoothness parameter $\beta$ of the demand function ...

    Abstract We study the dynamic pricing problem where the demand function is nonparametric and H\"older smooth, and we focus on adaptivity to the unknown H\"older smoothness parameter $\beta$ of the demand function. Traditionally the optimal dynamic pricing algorithm heavily relies on the knowledge of $\beta$ to achieve a minimax optimal regret of $\widetilde{O}(T^{\frac{\beta+1}{2\beta+1}})$. However, we highlight the challenge of adaptivity in this dynamic pricing problem by proving that no pricing policy can adaptively achieve this minimax optimal regret without knowledge of $\beta$. Motivated by the impossibility result, we propose a self-similarity condition to enable adaptivity. Importantly, we show that the self-similarity condition does not compromise the problem's inherent complexity since it preserves the regret lower bound $\Omega(T^{\frac{\beta+1}{2\beta+1}})$. Furthermore, we develop a smoothness-adaptive dynamic pricing algorithm and theoretically prove that the algorithm achieves this minimax optimal regret bound without the prior knowledge $\beta$.

    Comment: Minor typo errors corrected in the latest version
    Keywords Statistics - Machine Learning ; Computer Science - Machine Learning ; Economics - Econometrics
    Subject code 330
    Publishing date 2023-10-11
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Structural performance of detachable precast concrete column-column joint.

    Zhan, H / Ye, M / Jiang, J / Gao, Y / Zheng, C W / Duan, S C

    Heliyon

    2024  Volume 10, Issue 5, Page(s) e27308

    Abstract: A novel type of detachable precast concrete column-column joint (DPC) is proposed in this study to solve the problems in current column-column dry connections including complex load path, uncertainty of structural stiffness of beam-column joints and ... ...

    Abstract A novel type of detachable precast concrete column-column joint (DPC) is proposed in this study to solve the problems in current column-column dry connections including complex load path, uncertainty of structural stiffness of beam-column joints and inconvenience for disassembly. The dry connection technology is applied by composing of steel plate and concrete. Finite element models of DPC were created to study its structural performance including hysteresis curve, skeleton curve, ductility, and energy dissipation capacity. The benchmark models are firstly established and validated against the test data and after that a small-scale parametric study is prepared. The effect of axial pressure ratio and eccentricity distance size on the seismic performance of DPC was studied. Results indict that the optimal value of axial pressure ratio ranges from 0.5 to 0.7. With increase of the axial pressure ratio, the ductility coefficient shows a decreasing trend in general. The eccentricity has little effect on the energy dissipation capacity of the joint.
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e27308
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  4. Article: Assessment of sepsis-associated encephalopathy by quantitative magnetic resonance spectroscopy in a rat model of cecal ligation and puncture.

    Liu, Siqi / Liu, Zhifeng / Wu, Gongfa / Ye, Haoyi / Wu, Zhihua / Yang, Zhengfei / Jiang, Shanping

    Heliyon

    2024  Volume 10, Issue 5, Page(s) e26836

    Abstract: ... performed on the animals in the subgroup O and subgroup N at 24 h, 48 h, and 72 h. The animals in the subgroup M were ... examined by magnetic resonance imaging (MRI) at 12 h after CLP. Compared with the sham group, the ratio ...

    Abstract Proton magnetic resonance spectroscopy (1H-MRS) is the only non-invasive technique to quantify neurometabolic compounds in the living brain. We used 1H-MRS to evaluate the brain metabolites in a rat model of Sepsis-associated encephalopathy (SAE) established by cecal ligation and puncture (CLP). 36 male Sprague-Dawley rats were randomly divided into sham and CLP groups. Each group was further divided into three subgroups: subgroup O, subgroup M, and subgroup N. Neurological function assessments were performed on the animals in the subgroup O and subgroup N at 24 h, 48 h, and 72 h. The animals in the subgroup M were examined by magnetic resonance imaging (MRI) at 12 h after CLP. Compared with the sham group, the ratio of N-acetylaspartate (NAA) to creatine (Cr) in the hippocampus was significantly lower in the CLP group. The respective ratios of lactate (Lac), myo-inositol (mIns), glutamate and glutamine (Glx), lipid (Lip), and choline (Cho) to Cr in the CLP group were clearly higher than those in the sham group. Cytochrome
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e26836
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  5. Article: [Prevalence of medicare antiviral drugs use and related factors in HIV-infected people in Ningbo].

    Ye, Z H / Jiang, H B / Tan, S W / Shi, H B / Chu, K / Zhang, D D

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2024  Volume 45, Issue 1, Page(s) 123–127

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Aged ; United States/epidemiology ; Humans ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; HIV Infections/diagnosis ; Retrospective Studies ; Prevalence ; Medicare ; Substance-Related Disorders ; Antiviral Agents/therapeutic use
    Chemical Substances Antiviral Agents
    Language Chinese
    Publishing date 2024-01-17
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20230606-00353
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  6. Article ; Online: Disturbance of mitochondrial dynamics in myocardium of broilers with pulmonary hypertension syndrome.

    Zhang, W / Li, M / Ye, X / Jiang, M / Wu, X / Tang, Z / Hu, L / Zhang, H / Li, Y / Pan, J

    British poultry science

    2024  Volume 65, Issue 2, Page(s) 154–164

    Abstract: 1. The following study investigated the relationship between pulmonary hypertension syndrome (PHS) and mitochondrial dynamics in broiler cardiomyocytes.2. An animal model for PHS was established by injecting broiler chickens with CM-32 cellulose ... ...

    Abstract 1. The following study investigated the relationship between pulmonary hypertension syndrome (PHS) and mitochondrial dynamics in broiler cardiomyocytes.2. An animal model for PHS was established by injecting broiler chickens with CM-32 cellulose particles. Broiler myocardial cells were cultured under hypoxic conditions to establish an
    MeSH term(s) Animals ; Hypertension, Pulmonary/etiology ; Hypertension, Pulmonary/veterinary ; Chickens ; Mitochondrial Dynamics ; Mitochondria ; Myocytes, Cardiac
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 956653-3
    ISSN 1466-1799 ; 0007-1668
    ISSN (online) 1466-1799
    ISSN 0007-1668
    DOI 10.1080/00071668.2024.2308277
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  7. Article: Ultraflexible PEDOT:PSS/IrO

    Wang, Xueying / Jiang, Wanqi / Yang, Huiran / Ye, Yifei / Zhou, Zhitao / Sun, Liuyang / Nie, Yanyan / Tao, Tiger H / Wei, Xiaoling

    Micromachines

    2024  Volume 15, Issue 4

    Abstract: Recent advancements in neural probe technology have become pivotal in both neuroscience research and the clinical management of neurological disorders. State-of-the-art developments have led to the advent of multichannel, high-density bidirectional ... ...

    Abstract Recent advancements in neural probe technology have become pivotal in both neuroscience research and the clinical management of neurological disorders. State-of-the-art developments have led to the advent of multichannel, high-density bidirectional neural interfaces that are adept at both recording and modulating neuronal activity within the central nervous system. Despite this progress, extant bidirectional probes designed for simultaneous recording and stimulation are beset with limitations, including elicitation of inflammatory responses and insufficient charge injection capacity. In this paper, we delineate the design and application of an innovative ultraflexible bidirectional neural probe engineered from polyimide. This probe is distinguished by its ability to facilitate high-resolution recordings and precise stimulation control in deep brain regions. Electrodes enhanced with a PEDOT:PSS/IrO
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi15040447
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  8. Article ; Online: MOCS, a novel classifier system integrated multimoics analysis refining molecular subtypes and prognosis for skin melanoma.

    Ye, Juelan / Liu, Fuchun / Zhang, Luoshen / Wu, Chunbiao / Jiang, Aimin / Xie, Tianying / Jiang, Hao / Li, Zhenxi / Luo, Peng / Jiao, Jian / Xiao, Jianru

    Journal of biomolecular structure & dynamics

    2024  , Page(s) 1–17

    Abstract: ... Communicated by Ramaswamy H. Sarma. ...

    Abstract Purpose: The present investigation focuses on Skin Cutaneous Melanoma (SKCM), a melanocytic carcinoma characterized by marked aggression, significant heterogeneity, and a complex etiological background, factors which collectively contribute to the challenge in prognostic determinations. We defined a novel classifier system specifically tailored for SKCM based on multiomics.
    Methods: We collected 423 SKCM samples with multi omics datasets to perform a consensus cluster analysis using 10 machine learning algorithms and verified in 2 independent cohorts. Clinical features, biological characteristics, immune infiltration pattern, therapeutic response and mutation landscape were compared between subtypes.
    Results: Based on consensus clustering algorithms, we identified two Multi-Omics-Based-Cancer-Subtypes (MOCS) in SKCM in TCGA project and validated in GSE19234 and GSE65904 cohorts. MOCS2 emerged as a subtype with poor prognosis, characterized by a complex immune microenvironment, dysfunctional anti-tumor immune state, high cancer stemness index, and genomic instability. MOCS2 exhibited resistance to chemotherapy agents like erlotinib and sunitinib while sensitive to rapamycin, NSC87877, MG132, and FH355. Additionally, ELSPBP1 was identified as the target involving in glycolysis and M2 macrophage infiltration in SKCM.
    Conclusions: MOCS classification could stably predict prognosis of SKCM; patients with a high cancer stemness index combined with genomic instability may be predisposed to an immune exhaustion state.Communicated by Ramaswamy H. Sarma.
    Language English
    Publishing date 2024-03-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2024.2329305
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  9. Article ; Online: Structural insight into TIPE1 functioning as a lipid transfer protein.

    Cao, Sujian / Zhang, Ye / Jiang, Haoqian / Hou, Xuben / Wang, Wei

    Journal of biomolecular structure & dynamics

    2023  Volume 41, Issue 23, Page(s) 14049–14062

    Abstract: ... signaling pathways.Communicated by Ramaswamy H. Sarma. ...

    Abstract As a member of the tumor necrosis factor-α-induced protein 8 (TNFAIP8/TIPE) family, TIPE1 has been found to be associated with many cellular signaling pathways in regulating apoptosis, autophagy, and tumorigenesis. However, the position of TIPE1 in the signaling network remains elusive. Here we present the crystal structure of zebrafish TIPE1 in complex with phosphatidylethanolamine (PE) at a resolution of 1.38 Å. By comparison with structures of other three TIPE family proteins, a universal phospholipid-binding mode was proposed. Namely, the hydrophobic cavity binds to fatty acid tails, while 'X-R-R' triad nearby the entrance of cavity recognizes the phosphate group head. Using molecular dynamics (MD) simulations, we further elaborated the mechanism of how the lysine-rich N-terminal domain assisting TIPE1 to favorably bind to phosphatidylinositol (PI). Beside small molecule substrate, we identified Gαi3 as a direct-binding partner of TIPE1 using GST pull-down assay and size-exclusion chromatography. Analyses of key-residue mutations and predicted complex structure revealed that the binding mode of TIPE1 to Gαi3 could be non-canonical. In summary, our findings narrowed down TIPE1's position in Gαi3-related and PI-inducing signaling pathways.Communicated by Ramaswamy H. Sarma.
    MeSH term(s) Animals ; Intracellular Signaling Peptides and Proteins ; Zebrafish/metabolism ; Carcinogenesis ; Apoptosis Regulatory Proteins/metabolism
    Chemical Substances lipid transfer protein ; Intracellular Signaling Peptides and Proteins ; Apoptosis Regulatory Proteins
    Language English
    Publishing date 2023-03-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2023.2187641
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  10. Article ; Online: The Use of Dynamic Navigation Systems as a Component of Digital Dentistry.

    Tang, W L / Chao, X Y / Ye, Z / Liu, M W / Jiang, H

    Journal of dental research

    2023  Volume 103, Issue 2, Page(s) 119–128

    Abstract: The development of dynamic navigation system (DNS) has facilitated the development of modern digital medicine. In the field of dentistry, the cutting-edge technology is garnering widespread recognition. Based on the principles of 3-dimensional ... ...

    Abstract The development of dynamic navigation system (DNS) has facilitated the development of modern digital medicine. In the field of dentistry, the cutting-edge technology is garnering widespread recognition. Based on the principles of 3-dimensional visualization, virtual design, and precise motion tracking, DNS is mainly composed of a computer, a tracking system, specialized tracer instruments, and navigation software. DNS employs a workflow that begins with preoperative data acquisition and imaging data reconstruction, followed by surgical instrument calibration and spatial registration, culminating in real-time guided operations. Currently, the system has been applied in a broad spectrum of dental procedures, encompassing dental implants, oral and maxillofacial surgery (such as tooth extraction, the treatment of maxillofacial fractures, tumors, and foreign bodies, orthognathic surgery, and temporomandibular joint ankylosis surgery), intraosseous anesthesia, and endodontic treatment (including root canal therapy and endodontic surgery). These applications benefit from its enhancements in direct visualization, treatment precision, efficiency, safety, and procedural adaptability. However, the adoption of DNS is not without substantial upfront costs, required comprehensive training, additional preparatory time, and increased radiation exposure. Despite challenges, the ongoing advancements in DNS are poised to broaden its utility and substantially strengthen digital dentistry.
    MeSH term(s) Surgery, Computer-Assisted/methods ; Software ; Facial Bones ; Image Processing, Computer-Assisted ; Surgery, Oral
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80207-4
    ISSN 1544-0591 ; 0022-0345
    ISSN (online) 1544-0591
    ISSN 0022-0345
    DOI 10.1177/00220345231212811
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