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  1. Book: Endocrinology and the prostate

    Labrie, Fernand

    (Best practice & research : Clinical endocrinology & metabolism ; 22,2)

    2008  

    Author's details F. Labrie, guest ed
    Series title Best practice & research : Clinical endocrinology & metabolism ; 22,2
    Best practice & research
    Best practice & research ; Clinical endocrinology & metabolism
    Collection Best practice & research
    Best practice & research ; Clinical endocrinology & metabolism
    Language English
    Size IX S., S. 208 - 402 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT015540686
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 1075 -22,2- verfügbar in Königswinter Königswinter

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  2. Book ; Conference proceedings: Prostate cancer

    Labrie, Fernand

    understanding the pathophysiology and re-designing a therapeutic approach

    2004  

    Event/congress European Cancer Conference (12, 2003, Kopenhagen)
    Author's details ed. Fernand Labrie ... [ECCO meeting in September 2003 ... Copenhagen]
    Language English
    Size XII, 227 S. : Ill., graph. Darst.
    Publisher PMP, Paschalidis Med. Publ
    Publishing place Athens
    Publishing country Greece
    Document type Book ; Conference proceedings
    HBZ-ID HT014107219
    ISBN 960-399-195-3 ; 978-960-399-195-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 4593 order for loan Magazin

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  3. Article ; Online: The major role of androgens in prostate cancer and the need for more efficient blockade.

    Labrie, Fernand

    Expert review of endocrinology & metabolism

    2019  Volume 6, Issue 3, Page(s) 313–316

    Language English
    Publishing date 2019-02-12
    Publishing country England
    Document type Journal Article
    ISSN 1744-8417
    ISSN (online) 1744-8417
    DOI 10.1586/eem.11.5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Intracrinology and menopause: the science describing the cell-specific intracellular formation of estrogens and androgens from DHEA and their strictly local action and inactivation in peripheral tissues.

    Labrie, Fernand

    Menopause (New York, N.Y.)

    2018  Volume 26, Issue 2, Page(s) 220–224

    Abstract: The secretion of estrogens by the ovaries stops at menopause. Afterward, dehydroepiandrosterone (DHEA) becomes the only source of both estrogens and androgens during all the postmenopausal years. To maintain very low and biologically inactive ... ...

    Abstract The secretion of estrogens by the ovaries stops at menopause. Afterward, dehydroepiandrosterone (DHEA) becomes the only source of both estrogens and androgens during all the postmenopausal years. To maintain very low and biologically inactive concentrations of estrogens and androgens in the circulation, DHEA is transformed intracellularly into cell-specific small amounts of estrogens and androgens (except in the endometrium) which then act and are inactivated locally in the same cells, thus avoiding biologically significant systemic exposure to active sex steroids. The secretion of DHEA, however, mainly of adrenal origin, has already decreased by an average of 60% at the time of menopause and it continues to decrease thereafter with a parallel lowering in available intracellular estrogens and androgens. Consequently, after the arrest of estrogen secretion by the ovaries, the loss of DHEA becomes practically responsible for the symptoms and signs of menopause. Replacing what is missing, namely DHEA, at the right place, at the right time, and in the right amount, seems to be the logical and physiological approach for the treatment of menopausal symptoms and signs, as recently demonstrated for pain at sexual activity (dyspareunia), the most bothersome symptom of vulvovaginal atrophy due to menopause.
    MeSH term(s) Aged ; Androgens/metabolism ; Dehydroepiandrosterone/blood ; Endocrinology/methods ; Estradiol/blood ; Estrogens/metabolism ; Female ; Humans ; Hymen/metabolism ; Menopause/physiology ; Middle Aged ; Ovary/cytology ; Ovary/metabolism ; Testosterone/blood
    Chemical Substances Androgens ; Estrogens ; Testosterone (3XMK78S47O) ; Dehydroepiandrosterone (459AG36T1B) ; Estradiol (4TI98Z838E)
    Language English
    Publishing date 2018-08-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1205262-0
    ISSN 1530-0374 ; 1072-3714
    ISSN (online) 1530-0374
    ISSN 1072-3714
    DOI 10.1097/GME.0000000000001177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4111: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book: Localized prostate cancer

    Labrie, Fernand

    advances in diagnosis and treatment

    1996  

    Institution Society for Endocrinology
    Author's details Society of Endocrinology. Ed. by F. Labrie
    Keywords Prostatic Neoplasms / diagnosis / collected works ; Prostatic Neoplasms / therapy / collected works
    Language English
    Size S148 S. : Ill., graph. Darst.
    Publisher Soc. for Endocrinology
    Publishing place Bristol
    Publishing country Great Britain
    Document type Book
    Note Aus: Journal endocrine related cancer ; 3.1996
    HBZ-ID HT008063818
    ISBN 1-898099-11-1 ; 978-1-898099-11-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1998 A 324 order for loan Magazin

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  6. Book ; Conference proceedings: Program and abstracts / International Symposium on Recent Advances in Diagnosis and Treatment of Prostate Cancer

    Labrie, Fernand

    Québec City, September 21 - 23, 95

    1995  

    Institution International Symposium on Recent Advances in Diagnosis and Treatment of Prostate Cancer
    Author's details [international organizing committee Fernand Labrie ...]
    Language English
    Size 56 S. : Ill.
    Publishing place S.l.
    Publishing country Canada
    Document type Book ; Conference proceedings
    HBZ-ID HT013647106
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1996 A 8028 order for loan Magazin

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  7. Article ; Online: Each tissue becomes master of its sex steroid environment at menopause.

    Labrie, Fernand

    Climacteric : the journal of the International Menopause Society

    2015  Volume 18, Issue 5, Page(s) 764–765

    MeSH term(s) Animals ; Female ; Humans ; Menopause/physiology
    Language English
    Publishing date 2015-08-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1469153-x
    ISSN 1473-0804 ; 1369-7137
    ISSN (online) 1473-0804
    ISSN 1369-7137
    DOI 10.3109/13697137.2015.1070477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5245: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Prostate cancer: Bicalutamide dose increase in castration-resistant disease.

    Labrie, Fernand

    Nature reviews. Urology

    2015  Volume 12, Issue 3, Page(s) 132–133

    MeSH term(s) Androgen Antagonists/therapeutic use ; Anilides/therapeutic use ; Antineoplastic Agents/therapeutic use ; Humans ; Male ; Orchiectomy ; Prostatic Neoplasms/drug therapy
    Chemical Substances Androgen Antagonists ; Anilides ; Antineoplastic Agents
    Language English
    Publishing date 2015-03
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 2493737-X
    ISSN 1759-4820 ; 1759-4812
    ISSN (online) 1759-4820
    ISSN 1759-4812
    DOI 10.1038/nrurol.2014.334
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6030: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Postmenopausal cell and tissue sex-hormone metabolism: mechanisms of intracrinology.

    Labrie, Fernand

    Climacteric : the journal of the International Menopause Society

    2015  Volume 18, Issue 1, Page(s) 101–102

    MeSH term(s) Estrogens/biosynthesis ; Female ; Humans ; Menopause ; Ovary/metabolism ; Progesterone/biosynthesis ; Steroids/biosynthesis
    Chemical Substances Estrogens ; Steroids ; Progesterone (4G7DS2Q64Y)
    Language English
    Publishing date 2015-02
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 1469153-x
    ISSN 1473-0804 ; 1369-7137
    ISSN (online) 1473-0804
    ISSN 1369-7137
    DOI 10.3109/13697137.2015.993530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5245: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Book ; Conference proceedings: International Symposium: Advances in Diagnosis and Treatment of Early Stage Prostate Cancer

    Labrie, Fernand

    Québec City, Québec, May 29 - 30, 1993

    (Clinical and investigative medicine ; 16,6)

    1993  

    Title variant Advances in diagnosis and treatment of early stage prostate cancer
    Event/congress International Symposium Advances in Diagnosis and Treatment of Early Stage Prostate Cancer (1993, Québec)
    Author's details [symposium eds.: Fernand Labrie]
    Series title Clinical and investigative medicine ; 16,6
    Keywords Prostatic Neoplasms / diagnosis / congresses ; Prostatic Neoplasms / therapy / congresses
    Language English
    Size S. 407 - 538 : Ill., graph. Darst.
    Publisher Univ. of Toronto Pr
    Publishing place Toronto
    Publishing country Canada
    Document type Book ; Conference proceedings
    HBZ-ID HT006309316
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1389 -16- verfügbar in Königswinter Königswinter

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