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  1. Article: The Future Path To China's Poverty Reduction-Dynamic Decomposition Analysis With The Evolution Of China's Poverty Reduction Policies.

    Fang, Yingfeng / Zhang, Fen

    Social indicators research

    2021  Volume 158, Issue 2, Page(s) 507–538

    Abstract: The paper uses the Shapley method to decompose poverty changes by income source and growth-distribution-cost according to the history of China's poverty elimination policies in the last forty years. The analysis shows that economic growth contributed to ... ...

    Abstract The paper uses the Shapley method to decompose poverty changes by income source and growth-distribution-cost according to the history of China's poverty elimination policies in the last forty years. The analysis shows that economic growth contributed to most of the reduction in all periods. Increasing inequality has adverse effects on poverty elimination in that it makes people vulnerable to poverty, which bodes ill for future poverty alleviation. Wages explain most of poverty change for both the urban and rural areas in recent years and are the main reason for increasing inequality in rural areas. Agricultural income played a significant role in reducing rural poverty and inequality in early periods when China experienced many agricultural reforms. In the future, pro-poor growth, reducing inequality and building a relatively integrated urban-rural poverty alleviation system will be most important jobs for China's poverty reduction.
    Language English
    Publishing date 2021-05-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2018687-3
    ISSN 1573-0921 ; 0303-8300
    ISSN (online) 1573-0921
    ISSN 0303-8300
    DOI 10.1007/s11205-021-02716-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Governance Capability of the Public Health System

    Yingfeng Fang / Fen Zhang / Chenyu Zhou / Ming Chen

    International Journal of Environmental Research and Public Health, Vol 18, Iss 4210, p

    A Comparative Analysis of the Control of COVID-19 in the Different Provinces of China

    2021  Volume 4210

    Abstract: At the beginning of 2020, the global outbreak of the novel coronavirus COVID-19 posed a huge challenge to the governance capabilities of public health in various countries. In this paper, the SEIR model is used to fit the number of confirmed cases in ... ...

    Abstract At the beginning of 2020, the global outbreak of the novel coronavirus COVID-19 posed a huge challenge to the governance capabilities of public health in various countries. In this paper, the SEIR model is used to fit the number of confirmed cases in each province in China, and the reduction rate of the basic reproduction number is used to measure the actual score of the control effect of COVID-19. The potential capacity of prevention and control of epidemics, in theory, is constructed, and we use the difference between theoretical ability and actual score to measure the ability of governance of public health. We found that there were significant differences between actual effect and theoretical ability in various regions, and governance capabilities were an important reason leading to this difference, which was not consistent with the level of economic development. The balance of multiple objectives, the guiding ideology of emphasizing medical treatment over prevention, the fragmentation of the public health system, and the insufficiency of prevention and control ability in primary public health systems seriously affected the government’s ability to respond to public health emergencies.
    Keywords public health ; epidemic control ; SEIR model ; governance capability ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Toward the bioactive potential of myricitrin in food production: state-of-the-art green extraction and trends in biosynthesis.

    Geng, Yaqian / Xie, Yingfeng / Li, Wei / Mou, Yao / Chen, Fang / Xiao, Jianbo / Liao, Xiaojun / Hu, Xiaosong / Ji, Junfu / Ma, Lingjun

    Critical reviews in food science and nutrition

    2023  , Page(s) 1–27

    Abstract: Myricitrin is a member of flavonols, natural phenolic compounds extracted from plant resources. It has gained great attention for various biological activities, such as anti-inflammatory, anti-cancer, anti-diabetic, as well as cardio-/neuro-/ ... ...

    Abstract Myricitrin is a member of flavonols, natural phenolic compounds extracted from plant resources. It has gained great attention for various biological activities, such as anti-inflammatory, anti-cancer, anti-diabetic, as well as cardio-/neuro-/hepatoprotective activities. These effects have been demonstrated in both
    Language English
    Publishing date 2023-07-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1037504-1
    ISSN 1549-7852 ; 1040-8398
    ISSN (online) 1549-7852
    ISSN 1040-8398
    DOI 10.1080/10408398.2023.2227262
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Governance Capability of the Public Health System: A Comparative Analysis of the Control of COVID-19 in the Different Provinces of China.

    Fang, Yingfeng / Zhang, Fen / Zhou, Chenyu / Chen, Ming

    International journal of environmental research and public health

    2021  Volume 18, Issue 8

    Abstract: At the beginning of 2020, the global outbreak of the novel coronavirus COVID-19 posed a huge challenge to the governance capabilities of public health in various countries. In this paper, the SEIR model is used to fit the number of confirmed cases in ... ...

    Abstract At the beginning of 2020, the global outbreak of the novel coronavirus COVID-19 posed a huge challenge to the governance capabilities of public health in various countries. In this paper, the SEIR model is used to fit the number of confirmed cases in each province in China, and the reduction rate of the basic reproduction number is used to measure the actual score of the control effect of COVID-19. The potential capacity of prevention and control of epidemics, in theory, is constructed, and we use the difference between theoretical ability and actual score to measure the ability of governance of public health. We found that there were significant differences between actual effect and theoretical ability in various regions, and governance capabilities were an important reason leading to this difference, which was not consistent with the level of economic development. The balance of multiple objectives, the guiding ideology of emphasizing medical treatment over prevention, the fragmentation of the public health system, and the insufficiency of prevention and control ability in primary public health systems seriously affected the government's ability to respond to public health emergencies.
    MeSH term(s) Basic Reproduction Number ; COVID-19 ; China ; Humans ; Public Health ; SARS-CoV-2
    Language English
    Publishing date 2021-04-15
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph18084210
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: N-nitrosamines in processed meats

    Yingfeng Xie / Yaqian Geng / Jinbo Yao / Junfu Ji / Fang Chen / Jianbo Xiao / Xiaosong Hu / Lingjun Ma

    Journal of Agriculture and Food Research, Vol 13, Iss , Pp 100645- (2023)

    Exposure, formation and mitigation strategies

    2023  

    Abstract: Nitrite and nitrate have been widely used in the preservation of meat products for the effective antimicrobial action against several pathogenic bacteria such as Clostridium botulinum, Salmonella and mesophilic bacteria. However, they can further react ... ...

    Abstract Nitrite and nitrate have been widely used in the preservation of meat products for the effective antimicrobial action against several pathogenic bacteria such as Clostridium botulinum, Salmonella and mesophilic bacteria. However, they can further react with secondary amines in meat products and produce noxious compounds called nitrosamines during thermal processing. N-nitrosamines are divided into volatile N-nitrosamines and non-volatile N-nitrosamines, among which volatile N-nitrosamines are a group of highly hazardous chemical carcinogens whose carcinogenicity and teratogenicity have led to widespread concern. Owing to their occurrence in daily diet, it is of great significance to suppress their formation and toxicity on human health without causing adverse effects on food flavors. In this paper, the formation mechanism and toxicity of nitrosamines are provided. Potential mitigations can be carried out from the perspectives of precursors in raw materials, processing conditions as well as exogenous additives. Moreover, promoting the degradation of nitrosamines is an effective approach. The potential health risks associated with nitrosamines are described. Different intervention substances, such as polyphenols, vitamins and various plant extracts are summarized, discussing their impact on various toxicity of nitrosamines. The purpose of this review is to provide theoretical guidance on the control of nitrosamines generation and deleterious effects, so as to promote the development of meat processing and practical production.
    Keywords Nitrosamines ; Formation ; Mitigation ; Toxicity ; Intervention ; Agriculture (General) ; S1-972 ; Nutrition. Foods and food supply ; TX341-641
    Subject code 590
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study.

    Yu, Huai / Dai, Jiannan / Tang, Hao / Fang, Chao / Jiang, Senqing / Xu, Xueming / Yu, Bo / Tu, Yingfeng

    The international journal of cardiovascular imaging

    2023  Volume 39, Issue 7, Page(s) 1357–1366

    Abstract: Coronary artery ectasia (CAE) in adults is often caused by atherosclerotic plaques. CAE can affect atherosclerotic plaques through hemodynamic changes. However, no study has evaluated the characteristics of CAE with atherosclerotic plaques. Therefore, we ...

    Abstract Coronary artery ectasia (CAE) in adults is often caused by atherosclerotic plaques. CAE can affect atherosclerotic plaques through hemodynamic changes. However, no study has evaluated the characteristics of CAE with atherosclerotic plaques. Therefore, we aimed to disclose the characteristics of atherosclerotic plaques in patients with CAE using optical coherence tomography (OCT). We evaluated patients with CAE, confirmed by coronary angiography, who underwent pre-intervention OCT between April 2015 and April 2021. Each millimeter of the OCT images was analyzed to assess the characteristics of CAEs, plaque phenotypes, and plaque vulnerability. A total of 286 patients (344 coronary vessels) met our criteria, 82.87% of whom were men. Right coronary artery lesions were the most common, comprising 44.48% (n = 153) of the total. We found 329 CAE vessels with plaques, accounting for 95.64% of the coronary vessels. After grouping CAEs and plaques by their relative positions, we found that the length of plaques within CAE lesions was longer than that of plaques in other sites (P < 0.001). Plaques within CAE lesions had greater maximum lipid angles and lipid indexes (P = 0.007, P = 0.004, respectively) than those on other sites. This study revealed the most common vascular and morphological characteristics of CAE. While the accompanying plaques were not affected by the location or morphology of the CAE vessels, they were affected by their position relative to the CAE lesion.
    MeSH term(s) Humans ; Plaque, Atherosclerotic/pathology ; Tomography, Optical Coherence/methods ; Coronary Vessels/diagnostic imaging ; Coronary Vessels/pathology ; Dilatation, Pathologic ; Predictive Value of Tests ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/pathology ; Coronary Angiography/methods ; Vascular Diseases ; Coronary Aneurysm/pathology ; Lipids
    Chemical Substances Lipids
    Language English
    Publishing date 2023-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2055311-0
    ISSN 1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
    ISSN (online) 1875-8312 ; 1573-0743
    ISSN 1569-5794 ; 0167-9899
    DOI 10.1007/s10554-023-02835-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Plasma Exosomal CXCL7 is a Potential Biomarker for Lung Adenocarcinoma.

    Fang, Wenting / You, Jianbin / Xu, Qifeng / Jiang, Yingfeng / Hu, Haizhou / Chen, Falin / Chen, Liangyuan

    Clinical laboratory

    2022  Volume 68, Issue 10

    Abstract: Background: Lung cancer is a leading cause of cancer-related death, with lung adenocarcinoma (LUAD) representing the most common subtype. Recently, exosome-based biomarkers have provided new diagnostic approaches for malignancies.: Methods: The ... ...

    Abstract Background: Lung cancer is a leading cause of cancer-related death, with lung adenocarcinoma (LUAD) representing the most common subtype. Recently, exosome-based biomarkers have provided new diagnostic approaches for malignancies.
    Methods: The differential expression profile of plasma exosomal mRNA was established by high-throughput sequencing, and the expression and diagnostic value of plasma exosomal CXCL7 mRNA and protein in LUAD were studied to evaluate their diagnostic value as tumor biomarkers.
    Results: The expression of plasma exosomal CXCL7 mRNA in patients with LUAD was significantly increased (p < 0.01), which had no significant correlation with age, gender, and stage. ROC was used to evaluate the diagnostic value of plasma exosomal CXCL7 mRNA in LUAD patients with AUC = 0.7171. Further analysis signified that the CXCL7 protein of plasma exosomes in LUAD patients was overexpressed, and it was positively correlated with TNM stage and age. The diagnostic value of plasma exosomal CXCL7 in LUAD is better than serum CEA, with an AUC of 0.785, which has higher sensitivity and specificity.
    Conclusions: This research suggests that plasma exosomal CXCL7 may become an effective biomarker for early diagnosis of LUAD.
    MeSH term(s) Adenocarcinoma of Lung/diagnosis ; Biomarkers, Tumor/genetics ; Exosomes/metabolism ; Humans ; Lung Neoplasms/pathology ; RNA, Messenger/genetics
    Chemical Substances Biomarkers, Tumor ; RNA, Messenger
    Language English
    Publishing date 2022-06-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1307629-2
    ISSN 1433-6510 ; 0941-2131
    ISSN 1433-6510 ; 0941-2131
    DOI 10.7754/Clin.Lab.2022.220128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Highly efficient and robust π-FISH rainbow for multiplexed in situ detection of diverse biomolecules

    Yingfeng Tao / Xiaoliu Zhou / Leqiang Sun / Da Lin / Huaiyuan Cai / Xi Chen / Wei Zhou / Bing Yang / Zhe Hu / Jing Yu / Jing Zhang / Xiaoqing Yang / Fang Yang / Bang Shen / Wenbao Qi / Zhenfang Fu / Jinxia Dai / Gang Cao

    Nature Communications, Vol 14, Iss 1, Pp 1-

    2023  Volume 15

    Abstract: Fluorescence in situ hybridization (FISH) methods with high sensitivity are needed. Here the authors develop multiplex πFISH rainbow to detect a range of biomolecules; they also combine this with the hybridization chain reaction to develop πFISH+ ... ...

    Abstract Fluorescence in situ hybridization (FISH) methods with high sensitivity are needed. Here the authors develop multiplex πFISH rainbow to detect a range of biomolecules; they also combine this with the hybridization chain reaction to develop πFISH+ technology for short nucleic acid fragment detection.
    Keywords Science ; Q
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Identification of hub genes and discovery of promising compounds in gastric cancer based on bioinformatics analysis.

    Huang, Jiani / Wen, Fang / Huang, Wenjie / Bai, Yingfeng / Lu, Xiaona / Shu, Peng

    Biomarkers in medicine

    2020  Volume 14, Issue 12, Page(s) 1069–1084

    Abstract: Aim: ...

    Abstract Aim:
    MeSH term(s) Amiodarone/chemistry ; Cell Cycle Proteins/genetics ; Clomipramine/chemistry ; Collagen Type I/genetics ; Databases, Genetic ; Datasets as Topic ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Genes, Neoplasm ; Humans ; Ki-67 Antigen/genetics ; Levallorphan/chemistry ; Microtubule-Associated Proteins/genetics ; Neoplasm Proteins/genetics ; Osteopontin/genetics ; Piroxicam/chemistry ; Procaine/chemistry ; Procaine/pharmacology ; Procaine/therapeutic use ; Protein Serine-Threonine Kinases/genetics ; Proto-Oncogene Proteins/genetics ; Resveratrol/chemistry ; Resveratrol/pharmacology ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Small Molecule Libraries/therapeutic use ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/genetics ; Ursodeoxycholic Acid/chemistry ; Vorinostat/chemistry ; Polo-Like Kinase 1
    Chemical Substances Cell Cycle Proteins ; Collagen Type I ; Ki-67 Antigen ; Microtubule-Associated Proteins ; Neoplasm Proteins ; Proto-Oncogene Proteins ; SPP1 protein, human ; Small Molecule Libraries ; TPX2 protein, human ; Osteopontin (106441-73-0) ; Piroxicam (13T4O6VMAM) ; Levallorphan (353613BU4U) ; Procaine (4Z8Y51M438) ; Vorinostat (58IFB293JI) ; Ursodeoxycholic Acid (724L30Y2QR) ; Protein Serine-Threonine Kinases (EC 2.7.11.1) ; Amiodarone (N3RQ532IUT) ; Clomipramine (NUV44L116D) ; Resveratrol (Q369O8926L)
    Language English
    Publishing date 2020-09-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2481014-9
    ISSN 1752-0371 ; 1752-0363
    ISSN (online) 1752-0371
    ISSN 1752-0363
    DOI 10.2217/bmm-2019-0608
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Highly efficient and robust π-FISH rainbow for multiplexed in situ detection of diverse biomolecules.

    Tao, Yingfeng / Zhou, Xiaoliu / Sun, Leqiang / Lin, Da / Cai, Huaiyuan / Chen, Xi / Zhou, Wei / Yang, Bing / Hu, Zhe / Yu, Jing / Zhang, Jing / Yang, Xiaoqing / Yang, Fang / Shen, Bang / Qi, Wenbao / Fu, Zhenfang / Dai, Jinxia / Cao, Gang

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 443

    Abstract: In the unprecedented single-cell sequencing and spatial multiomics era of biology, fluorescence in situ hybridization (FISH) technologies with higher sensitivity and robustness, especially for detecting short RNAs and other biomolecules, are greatly ... ...

    Abstract In the unprecedented single-cell sequencing and spatial multiomics era of biology, fluorescence in situ hybridization (FISH) technologies with higher sensitivity and robustness, especially for detecting short RNAs and other biomolecules, are greatly desired. Here, we develop the robust multiplex π-FISH rainbow method to detect diverse biomolecules (DNA, RNA, proteins, and neurotransmitters) individually or simultaneously with high efficiency. This versatile method is successfully applied to detect gene expression in different species, from microorganisms to plants and animals. Furthermore, we delineate the landscape of diverse neuron subclusters by decoding the spatial distribution of 21 marker genes via only two rounds of hybridization. Significantly, we combine π-FISH rainbow with hybridization chain reaction to develop π-FISH+ technology for short nucleic acid fragments, such as microRNA and prostate cancer anti-androgen therapy-resistant marker ARV7 splicing variant in circulating tumour cells from patients. Our study provides a robust biomolecule in situ detection technology for spatial multiomics investigation and clinical diagnosis.
    MeSH term(s) Humans ; Male ; Animals ; In Situ Hybridization, Fluorescence/methods ; MicroRNAs/genetics ; Prostatic Neoplasms/diagnosis ; Prostatic Neoplasms/genetics ; Nucleic Acids
    Chemical Substances MicroRNAs ; Nucleic Acids
    Language English
    Publishing date 2023-01-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-36137-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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