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  1. Article: Synergistic Anticandidal Effects of Six Essential Oils in Combination with Fluconazole or Amphotericin B against Four Clinically Isolated

    Soulaimani, Bouchra / Varoni, Elena / Iriti, Marcello / Mezrioui, Nour-Eddine / Hassani, Lahcen / Abbad, Abdelaziz

    Antibiotics (Basel, Switzerland)

    2021  Volume 10, Issue 9

    Abstract: The development of opportunistic ... ...

    Abstract The development of opportunistic pathogenic
    Language English
    Publishing date 2021-08-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics10091049
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  2. Article ; Online: Lack of Ser267Phe variant of sodium taurocholate cotransporting polypeptide among Moroccans regardless of hepatitis B virus infection status.

    Ezzikouri, Sayeh / Chihab, Hajar / Elhabazi, Abdellah / Wakrim, Lahcen / Benjelloun, Soumaya

    BMC infectious diseases

    2017  Volume 17, Issue 1, Page(s) 99

    Abstract: ... identified as a functional receptor for hepatitis B virus (HBV). The objective of this study was to determine ... in 286 chronic hepatitis B patients, 135 individuals with spontaneous clearance from HBV infection and ... 109 healthy controls negative for hepatitis B serological markers.: Results: In this cohort ...

    Abstract Background: The sodium taurocholate co-transporting polypeptide, encoded by SLC10A1, was identified as a functional receptor for hepatitis B virus (HBV). The objective of this study was to determine if there was an association of the Ser267Phe variant (rs2296651) with HBV infection status in Moroccan patients.
    Methods: Using a TaqMan 5' allelic discrimination assay, the Ser267Phe variant was genotyped in 286 chronic hepatitis B patients, 135 individuals with spontaneous clearance from HBV infection and 109 healthy controls negative for hepatitis B serological markers.
    Results: In this cohort, we detected only wild-type genotype (S267S) in all groups. This polymorphism was not associated with the HBV infection status in Moroccan patients.
    Conclusions: The S267F variant is absent among Moroccans regardless of chronic HBV infection status.
    MeSH term(s) Adult ; Aged ; Alleles ; European Continental Ancestry Group ; Female ; Hepatitis B virus/genetics ; Hepatitis B, Chronic/genetics ; Humans ; Male ; Middle Aged ; Morocco ; Organic Anion Transporters, Sodium-Dependent/genetics ; Polymorphism, Genetic ; Symporters/genetics ; Young Adult
    Chemical Substances Organic Anion Transporters, Sodium-Dependent ; Symporters ; sodium-bile acid cotransporter (145420-23-1)
    Language English
    Publishing date 2017-01-26
    Publishing country England
    Document type Journal Article
    ISSN 1471-2334
    ISSN (online) 1471-2334
    DOI 10.1186/s12879-017-2214-2
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  3. Article ; Online: Removal of the Rhodamine B Dye at Ti/Ru0.3Ti0.7O2 Anode Using Flow Cell System

    Ali Baddouh / Brahim El Ibrahimi / Elhassan Amaterz / M. Mohamed Rguiti / Lahcen Bazzi / Mustapha Hilali

    Journal of Chemistry, Vol

    2019  Volume 2019

    Abstract: The electrochemical oxidation of the Rhodamine B dye (Rh-B) was carried out using dimensionally ... electrolysis time, temperature, and initial concentration of Rh-B dye, were investigated. The UV-visible ... degradation of Rh-B. The best color removal achieved was found to be 98.3% after 10 min applying 3.9 mA·cm−2 ...

    Abstract The electrochemical oxidation of the Rhodamine B dye (Rh-B) was carried out using dimensionally stable type anode (DSA, Ti/Ru0.3Ti0.7O2). The work was performed using the electrochemical flow cell system. The effect of several operating factors, such as supporting electrolytes, current density, electrolysis time, temperature, and initial concentration of Rh-B dye, were investigated. The UV-visible spectroscopy and chemical oxygen demand (COD) measurements were conducted to monitor the removal and degradation of Rh-B. The best color removal achieved was found to be 98.3% after 10 min applying 3.9 mA·cm−2 as a current density using 0.07 mol·L−1 of NaCl. Meanwhile, the highest COD removal rate (93.0%) was obtained for an applied current density of 3.9 mA·cm−2 as the optimal operating condition after 180 min reaction time, with 2.98 kW h·m−3 as energy consumption. This shows that the best conditions for color removal are not certainly the same as those for the COD removal. The rises in the concentration of NaCl, and applied current increased the Rh-B color removal rate. The decline in Rh-B dye concentration followed pseudo-first-order kinetics. The obtained values of apparent rate constant were increased by increasing chloride ion concentration. It is concluded that the electro-oxidation on DSA electrode using a flow cell is a suitable process for the removal of Rh-B dye in aqueous solutions.
    Keywords Chemistry ; QD1-999
    Subject code 660
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
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  4. Article: Crystal structure of 2-amino-3-cyano-4-(4-meth-oxy-phen-yl)-4H-1-benzo-thieno[3,2-b]pyran.

    Bakhouch, Mohamed / El Yazidi, Mohamed / Kerbal, Abdelali / Saadi, Mohamed / El Ammari, Lahcen

    Acta crystallographica. Section E, Crystallographic communications

    2015  Volume 71, Issue Pt 12, Page(s) o1043–4

    Abstract: ... coplanar, with the maximum deviation from the mean plane being 0.060 (1) Å. This benzothieno[3,2-b]pyran ... along the b axis. The tapes are linked together by C-H⋯N and π-π inter-actions [centroid-centroid ...

    Abstract The three fused five- and six-membered rings in the title compound, C19H14N2O2S, are virtually coplanar, with the maximum deviation from the mean plane being 0.060 (1) Å. This benzothieno[3,2-b]pyran ring system is nearly perpendic-ular to the plane of the 4-meth-oxy-phenyl ring, forming a dihedral angle of 83.65 (5)°. In the crystal, mol-ecules are linked by pairs of N-H⋯N hydrogen bonds into inversion dimers. The dimeric units are further connected by an N-H⋯O hydrogen bond into a tape running along the b axis. The tapes are linked together by C-H⋯N and π-π inter-actions [centroid-centroid distance = 3.7743 (8) Å], forming a three-dimensional network.
    Language English
    Publishing date 2015-12-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 2056-9890 ; 1600-5368
    ISSN 2056-9890 ; 1600-5368
    DOI 10.1107/S2056989015023464
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  5. Article: Crystal structure of (Z)-2-benzyl-idene-4-methyl-2H-benzo[b][1,4]thia-zin-3(4H)-one.

    Ellouz, Mohamed / Sebbar, Nada Kheira / Essassi, El Mokhtar / Saadi, Mohamed / El Ammari, Lahcen

    Acta crystallographica. Section E, Crystallographic communications

    2015  Volume 71, Issue Pt 11, Page(s) o862–3

    Abstract: In the title compound, C16H13NOS, the 1,4-thia-zine ring displays a screw-boat conformation. The conformation about the ethene bond [1.344 (2) Å] is Z. The plane of the fused benzene ring makes a dihedral angle of 58.95 (9)° with the pendent phenyl ring, ...

    Abstract In the title compound, C16H13NOS, the 1,4-thia-zine ring displays a screw-boat conformation. The conformation about the ethene bond [1.344 (2) Å] is Z. The plane of the fused benzene ring makes a dihedral angle of 58.95 (9)° with the pendent phenyl ring, indicating a twisted conformation in the mol-ecule. In the crystal, mol-ecules are linked by pairs of C-H⋯O hydrogen bonds, forming inversion dimers.
    Language English
    Publishing date 2015-10-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 2056-9890 ; 1600-5368
    ISSN 2056-9890 ; 1600-5368
    DOI 10.1107/S2056989015019295
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  6. Article: Crystal structure of ethyl 2-amino-4-(4-chloro-phen-yl)-4H-1-benzothieno[3,2-b]pyran-3-carboxyl-ate.

    Bakhouch, Mohamed / Mahfoud, Asmae / El Yazidi, Mohamed / Saadi, Mohamed / El Ammari, Lahcen

    Acta crystallographica. Section E, Crystallographic communications

    2015  Volume 71, Issue Pt 8, Page(s) o619–20

    Abstract: The title compound, C20H16ClNO3S, is built up from three fused rings, one five- and two six-membered rings, linked to a 3-eth-oxy-carbonyl group and to a 4-chloro-phenyl ring. The hydropyran ring has a flattened envelope conformation, with the C atom ... ...

    Abstract The title compound, C20H16ClNO3S, is built up from three fused rings, one five- and two six-membered rings, linked to a 3-eth-oxy-carbonyl group and to a 4-chloro-phenyl ring. The hydropyran ring has a flattened envelope conformation, with the C atom substituted by the 4-chloro-phenyl ring as the flap (displaced by 0.077 (2) Å from the plane through the other atoms). The fused three-ring system is quasi-planar (r.m.s. deviation = 0.057 Å), with the largest deviation from the mean plane being 0.106 (1) Å for the C atom substituted by the 4-chloro-phenyl ring. The 4-chloro-phenyl ring is approximately perpendicular to the mean plane of the fused ring system, as indicated by the dihedral angle of 77.32 (6)° between their mean planes. There is an intra-molecular N-H⋯O hydrogen bond forming an S(6) ring motif. In the crystal, mol-ecules are linked by pairs of N-H⋯O hydrogen bonds, forming inversion dimers with an R 2 (2)(12) ring motif. There are also short inter-molecular Cl⋯O inter-actions present [3.1226 (12) Å] between neighbouring mol-ecules.
    Language English
    Publishing date 2015-07-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 2056-9890 ; 1600-5368
    ISSN 2056-9890 ; 1600-5368
    DOI 10.1107/S2056989015014085
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  7. Article: 3-Benzyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one.

    Kandri Rodi, Youssef / Haoudi, Amal / Capet, Frédéric / Mazzah, Ahmed / Essassi, El Mokhtar / El Ammari, Lahcen

    Acta crystallographica. Section E, Structure reports online

    2013  Volume 69, Issue Pt 6, Page(s) o962

    Abstract: The fused imidazole and pyridine rings in the title compound, C13H10BrN3O, are linked to a benzyl group. The fused ring system is essentially planar, the largest deviation from the mean plane being 0.006 (2) Å. The phenyl ring is not coplanar with the ... ...

    Abstract The fused imidazole and pyridine rings in the title compound, C13H10BrN3O, are linked to a benzyl group. The fused ring system is essentially planar, the largest deviation from the mean plane being 0.006 (2) Å. The phenyl ring is not coplanar with the fused ring system, as indicated by the dihedral angle of 67.04 (12)°. In the crystal, mol-ecules are linked by pairs of N-H⋯O hydrogen bonds, forming inversion dimers.
    Language English
    Publishing date 2013-05-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 1600-5368
    ISSN 1600-5368
    DOI 10.1107/S1600536813013780
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  8. Article ; Online: Crystal structure of 2-amino-3-cyano-4-(4-methoxyphenyl)-4H-1-benzothieno[3,2-b]pyran

    Mohamed Bakhouch / Mohamed El Yazidi / Abdelali Kerbal / Mohamed Saadi / Lahcen El Ammari

    Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 12, Pp o1043-o

    2015  Volume 1044

    Abstract: ... coplanar, with the maximum deviation from the mean plane being 0.060 (1) Å. This benzothieno[3,2-b]pyran ... dimers. The dimeric units are further connected by an N—H.O hydrogen bond into a tape running along the b ...

    Abstract The three fused five- and six-membered rings in the title compound, C19H14N2O2S, are virtually coplanar, with the maximum deviation from the mean plane being 0.060 (1) Å. This benzothieno[3,2-b]pyran ring system is nearly perpendicular to the plane of the 4-methoxyphenyl ring, forming a dihedral angle of 83.65 (5)°. In the crystal, molecules are linked by pairs of N—H.N hydrogen bonds into inversion dimers. The dimeric units are further connected by an N—H.O hydrogen bond into a tape running along the b axis. The tapes are linked together by C—H.N and π–π interactions [centroid–centroid distance = 3.7743 (8) Å], forming a three-dimensional network.
    Keywords crystal structure ; benzothino[3,2-b]pyran ; 2-amino-4-aryl-4H-pyran ; Chemistry ; QD1-999
    Language English
    Publishing date 2015-12-01T00:00:00Z
    Publisher International Union of Crystallography
    Document type Article ; Online
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  9. Article ; Online: Crystal structure of (Z)-2-benzylidene-4-methyl-2H-benzo[b][1,4]thiazin-3(4H)-one

    Mohamed Ellouz / Nada Kheira Sebbar / El Mokhtar Essassi / Mohamed Saadi / Lahcen El Ammari

    Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 11, Pp o862-o

    2015  Volume 863

    Abstract: In the title compound, C16H13NOS, the 1,4-thiazine ring displays a screw-boat conformation. The conformation about the ethene bond [1.344 (2) Å] is Z. The plane of the fused benzene ring makes a dihedral angle of 58.95 (9)° with the pendent phenyl ring, ... ...

    Abstract In the title compound, C16H13NOS, the 1,4-thiazine ring displays a screw-boat conformation. The conformation about the ethene bond [1.344 (2) Å] is Z. The plane of the fused benzene ring makes a dihedral angle of 58.95 (9)° with the pendent phenyl ring, indicating a twisted conformation in the molecule. In the crystal, molecules are linked by pairs of C—H.O hydrogen bonds, forming inversion dimers.
    Keywords crystal structure ; thiomorpholin-3-one derivative ; benzothiazine derivative ; hydrogen bonding ; Chemistry ; QD1-999
    Language English
    Publishing date 2015-11-01T00:00:00Z
    Publisher International Union of Crystallography
    Document type Article ; Online
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  10. Article: Ethyl 2-amino-4-(3-nitro-phen-yl)-4H-1-benzothieno[3,2-b]pyran-3-carboxyl-ate.

    Bakhouch, Mohamed / Al Houari, Ghali / El Yazidi, Mohamed / Saadi, Mohamed / El Ammari, Lahcen

    Acta crystallographica. Section E, Structure reports online

    2014  Volume 70, Issue Pt 5, Page(s) o587

    Abstract: The mol-ecule of the title compound, C20H16N2O5S, is built up by one fused five-membered and two fused six-membered rings linked to eth-oxy-carbonyl and 3-nitro-phenyl groups. The benzothieno-pyran ring system is nearly planar (r.m.s deviation = 0.0392 Å) ...

    Abstract The mol-ecule of the title compound, C20H16N2O5S, is built up by one fused five-membered and two fused six-membered rings linked to eth-oxy-carbonyl and 3-nitro-phenyl groups. The benzothieno-pyran ring system is nearly planar (r.m.s deviation = 0.0392 Å) and forms a dihedral angle of 86.90 (6)° with the aromatic ring of the nitro-benzene group. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds and by π-π inter-actions between the phenyl ring and the six-membered heterocyle [inter-centroid distance = 3.5819 (8) Å], forming a three-dimensional network.
    Language English
    Publishing date 2014-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 1600-5368
    ISSN 1600-5368
    DOI 10.1107/S1600536814008538
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