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  1. Book ; Online ; E-Book: Grief and Prolonged Grief Disorder

    Reynolds, Charles F., III. / Cozza, Stephen J. / Maciejewski, Paul K. / Prigerson, Holly G. / Shear, M. Katherine / Simon, Naomi / Zisook, Sidney

    2023  

    Abstract: With the publication of DSM-5-TR and in the context of considerable scientific progress, prolonged grief disorder (PGD) was included as a formal diagnosis. This new handbook provides both clinical and non-clinical readers with a science-based approach to ...

    Abstract With the publication of DSM-5-TR and in the context of considerable scientific progress, prolonged grief disorder (PGD) was included as a formal diagnosis. This new handbook provides both clinical and non-clinical readers with a science-based approach to identifying and addressing PGD, along with what might be termed "normal" grief.
    MeSH term(s) Prolonged Grief Disorder ; Grief
    Subject code 155.9/37
    Language English
    Size 1 online resource (224 pages)
    Edition 1st ed.
    Publisher American Psychiatric Association Publishing
    Publishing place Washington, D.C
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-61537-464-7 ; 978-1-61537-464-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: On the Road to Zero Suicide.

    Zisook, Sidney

    Focus (American Psychiatric Publishing)

    2018  Volume 16, Issue 4, Page(s) 7s–8s

    Language English
    Publishing date 2018-10-18
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1541-4094
    ISSN 1541-4094
    DOI 10.1176/appi.focus.164S13
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Pharmacologic Approaches to Suicide Prevention.

    Zisook, Sidney / Domingues, Isabel / Compton, Jason

    Focus (American Psychiatric Publishing)

    2023  Volume 21, Issue 2, Page(s) 137–144

    Abstract: Suicide is a leading cause of death that is often preventable. This article reviews the role of medications in treating suicidal behavior and in preventing suicide. For an acute suicidal crisis, ketamine, and perhaps esketamine, are emerging as important ...

    Abstract Suicide is a leading cause of death that is often preventable. This article reviews the role of medications in treating suicidal behavior and in preventing suicide. For an acute suicidal crisis, ketamine, and perhaps esketamine, are emerging as important tools. For patients with chronic suicidality, clozapine remains the only U.S. Food and Drug Administration (FDA) approved antisuicidal medication, and its use is predominantly for patients with schizophrenia and schizoaffective disorder. An abundance of literature supports the use of lithium among patients with mood disorders, including those with major depressive disorder. Despite the black box warning regarding antidepressants and suicide risk among children, adolescents, and young adults, antidepressants are widely used and remain helpful in reducing suicidal thoughts and behaviors, primarily among patients with mood disorders. Treatment guidelines focus on the importance of optimizing treatment of the psychiatric conditions known to be associated with suicide risk. For patients with these conditions, the authors recommend focusing on suicide as an independent treatment target and using an enhanced medication management strategy that includes maintaining a supportive, nonjudgmental therapeutic relationship; flexibility; collaboration; measurement-based care; consideration of combining medications with nonpharmacologic, evidence-based strategies; and ongoing safety planning.
    Language English
    Publishing date 2023-04-14
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1541-4094
    ISSN 1541-4094
    DOI 10.1176/appi.focus.20220076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Loneliness Among Medical Students, Physician Trainees and Faculty Physicians.

    Keiner, Cathrine / Nestsiarovich, Anastasiya / Celebi, Julie / Zisook, Sidney

    Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

    2023  

    Abstract: Objective: Aims of this study were to explore 1) how often medical students, residents, fellows, and faculty physicians who completed a suicide screening questionnaire at a large US academic medical center endorsed intense loneliness and 2) the ... ...

    Abstract Objective: Aims of this study were to explore 1) how often medical students, residents, fellows, and faculty physicians who completed a suicide screening questionnaire at a large US academic medical center endorsed intense loneliness and 2) the relationships of loneliness with other negative mental health states.
    Methods: Between May 2009 and September 2001, all medical students, residents, fellows, and faculty physicians were invited to complete an anonymous online questionnaire as part of a screening program to identify and engage individuals in distress with mental health support. The questionnaire assessed intense loneliness, other affective states known to be associated with suicide risk, burnout, depressive symptoms, and suicidal thoughts and behaviors. Chi-square tests, independent sample t-tests, ANOVA, and correlation analysis were used to examine relationships between loneliness and these other signals of suicide risk.
    Results: The response rate was  ~ 20%. Overall, 364 of 2016 respondents (18.1%) endorsed intense. loneliness "a lot" or "most" of the time. This included 134/641 (20.9%) medical students, 170/703 (24.2%) residents and fellows and 60/664 (9.4%) faculty physicians. A greater odds of endorsing intense loneliness was seen in those under age 40 (OR = 0.35, p < 0.001), women (OR = 1.30, p = 0.030), and non-Whites (OR = 1.70, p < 0.001); and in those with burnout (OR = 3.14, p < 0.001), depression (OR = 12.34, p < 0.001), other intense affective states (OR = 4.34-8.34, p < 0.05), and suicidal ideation (OR = 3.47-13.00, p < 0.001).
    Conclusion: Interventions to mitigate loneliness in healthcare trainees and professionals may help decrease burnout, depression, and other suicide risk factors. A limitation of the study was the use of a single item to assess loneliness.
    Language English
    Publishing date 2023-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1045331-3
    ISSN 1545-7230 ; 1042-9670
    ISSN (online) 1545-7230
    ISSN 1042-9670
    DOI 10.1007/s40596-023-01780-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Associations Between Privacy-Related Constructs and Depression and Suicide Risk in Health Care Professionals, Trainees, and Students.

    Rubanovich, Caryn Kseniya / Zisook, Sidney / Bloss, Cinnamon S

    Academic medicine : journal of the Association of American Medical Colleges

    2022  Volume 97, Issue 2, Page(s) 239–246

    Abstract: Purpose: The University of California, San Diego screens health care professionals, trainees, and students for depression and suicide risk. Individuals complete a voluntary, anonymous online screening tool and choose whether to provide personal ... ...

    Abstract Purpose: The University of California, San Diego screens health care professionals, trainees, and students for depression and suicide risk. Individuals complete a voluntary, anonymous online screening tool and choose whether to provide personal demographic information. This study assessed the relationship between privacy-related constructs and self-rated depression and suicide risk.
    Method: The authors analyzed responses to the screening tool collected from January 2018 to December 2019. Measures of depression, suicidal ideation and behaviors, and worry about stigma for seeking mental health services (i.e., privacy-related concern) were gathered. The number of demographic item nonresponses (i.e., age, gender, ethnicity/race, professional position) was operationalized as privacy-related behavior. Linear and logistic regression models were used to determine associations between privacy-related constructs (concern and behavior) and depression and suicide measures.
    Results: A total of 1,224 respondents were included. On average, respondents reported mild depression (mean = 9.12, standard deviation = 5.94), but 43% (524/1,224) reported at least moderate depression. One in 5 respondents (248/1,224) reported worry about stigma for seeking mental health services, and more than 17% (212/1,224) skipped at least 1 demographic question. Privacy-related concern was statistically significantly and positively associated with recent depression and suicidal ideation and behaviors (odds ratios [ORs] = 3.13-7.02; 95% confidence interval [CI], 2.23-19.20; P's < .001) and with lifetime suicide attempts (OR = 1.76; 95% CI, 1.08-2.86; P = .02). Privacy-related behavior was statistically significantly and positively associated with suicide action (OR = 2.23; 95% CI, 1.24-4.02; P = .008).
    Conclusions: Privacy-related constructs may be meaningful correlates of mental health as respondents who endorsed these constructs had increased odds of worse depression and suicidal ideation and behaviors. Considering privacy-related constructs may be useful for identifying health care professionals, trainees, and students experiencing distress and in need of imminent mental health resources.
    MeSH term(s) California ; Confidentiality/standards ; Depression/epidemiology ; Female ; Health Personnel/statistics & numerical data ; Humans ; Internship and Residency/statistics & numerical data ; Male ; Risk Factors ; Students/statistics & numerical data ; Suicide/statistics & numerical data
    Language English
    Publishing date 2022-04-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 96192-9
    ISSN 1938-808X ; 1040-2446
    ISSN (online) 1938-808X
    ISSN 1040-2446
    DOI 10.1097/ACM.0000000000004513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: How do serotonergic psychedelics treat depression: The potential role of neuroplasticity.

    Artin, Hewa / Zisook, Sidney / Ramanathan, Dhakshin

    World journal of psychiatry

    2021  Volume 11, Issue 6, Page(s) 201–214

    Abstract: Depression is a common mental disorder and one of the leading causes of disability around the world. Monoaminergic antidepressants often take weeks to months to work and are not effective for all patients. This has led to a search for a better ... ...

    Abstract Depression is a common mental disorder and one of the leading causes of disability around the world. Monoaminergic antidepressants often take weeks to months to work and are not effective for all patients. This has led to a search for a better understanding of the pathogenesis of depression as well as to the development of novel antidepressants. One such novel antidepressant is ketamine, which has demonstrated both clinically promising results and contributed to new explanatory models of depression, including the potential role of neuroplasticity in depression. Early clinical trials are now showing promising results of serotonergic psychedelics for depression; however, their mechanism of action remains poorly understood. This paper seeks to review the effect of depression, classic antidepressants, ketamine, and serotonergic psychedelics on markers of neuroplasticity at a cellular, molecular, electrophysiological, functional, structural, and psychological level to explore the potential role that neuroplasticity plays in the treatment response of serotonergic psychedelics.
    Language English
    Publishing date 2021-06-19
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2220-3206
    ISSN 2220-3206
    DOI 10.5498/wjp.v11.i6.201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Suicidal behavior across a broad range of psychiatric disorders.

    Xu, Yingcheng E / Barron, Daniel A / Sudol, Katherin / Zisook, Sidney / Oquendo, Maria A

    Molecular psychiatry

    2023  Volume 28, Issue 7, Page(s) 2764–2810

    Abstract: Suicide is a leading cause of death worldwide. In 2020, some 12.2 million Americans seriously contemplated suicide, 3.2 million planned suicide attempts, and 1.2 million attempted suicide. Traditionally, the approach to treating suicidal behavior (SB) ... ...

    Abstract Suicide is a leading cause of death worldwide. In 2020, some 12.2 million Americans seriously contemplated suicide, 3.2 million planned suicide attempts, and 1.2 million attempted suicide. Traditionally, the approach to treating suicidal behavior (SB) has been to treat the "underlying" psychiatric disorder. However, the number of diagnoses associated with SB is considerable. We could find no studies describing the range of disorders reported to be comorbid with SB. This narrative review summarizes literature documenting the occurrence of SB across the lifespan and the full range of psychiatric diagnoses, not only BPD and those that comprise MDE, It also describes the relevance of these observations to clinical practice, research, and nosology. The literature searches contained the terms "suicid*" and each individual psychiatric diagnosis and identified 587 studies. We did not include case reports, case series, studies only addressing suicidal ideation or non-suicidal self-injury (NSSI), studies on self-harm, not distinguishing between SB and NSSI and studies that did not include any individuals that met criteria for a specific DSM-5 diagnosis (n = 366). We found that SB (suicide and/or suicide attempt) was reported to be associated with 72 out of 145 diagnoses, although data quality varied. Thus, SB is not exclusively germane to Major Depressive Episode (MDE) and Borderline Personality Disorder (BPD), the only conditions for which it is a diagnostic criterion. That SB co-occurs with so many diagnoses reinforces the need to assess current and past SB regardless of diagnosis, and supports the addition of charting codes to the DSM-5 to indicate current or past SB. It also comports with new data that specific genes are associated with SB independent of psychiatric diagnoses, and suggests that SB should be managed with specific suicide prevention interventions in addition to treatments indicated for co-occurring diagnoses. SB diagnostic codes would help researchers and clinicians document and measure SB's trajectory and response to treatment over time, and, ultimately, help develop secondary and tertiary prevention strategies. As a separate diagnosis, SB would preclude situations in which a potentially life-threatening behavior is not accounted for by a diagnosis, a problem that is particularly salient when no mental disorder is present, as is sometimes the case.
    MeSH term(s) Humans ; Suicidal Ideation ; Depressive Disorder, Major ; Suicide, Attempted/psychology ; Self-Injurious Behavior/epidemiology ; Self-Injurious Behavior/psychology ; Borderline Personality Disorder/epidemiology ; Risk Factors
    Language English
    Publishing date 2023-01-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1330655-8
    ISSN 1476-5578 ; 1359-4184
    ISSN (online) 1476-5578
    ISSN 1359-4184
    DOI 10.1038/s41380-022-01935-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Grief and bereavement

    Zisook, Sidney

    (The Psychiatric clinics of North America ; 10,3)

    1987  

    Author's details Sidney Zisook, guest ed
    Series title The Psychiatric clinics of North America ; 10,3
    Psychiatric clinics of North America
    Collection Psychiatric clinics of North America
    Keywords Bereavement ; Grief
    Size XIII S., S. 329 - 515 : graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT003065733
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: Healthcare provider distress before and since Covid-19.

    Zisook, Sidney / Doran, Neal / Downs, Nancy / Lee, Daniel / Nestsiarovich, Anastasiya / Davidson, Judy E

    General hospital psychiatry

    2022  Volume 79, Page(s) 180–182

    MeSH term(s) Humans ; COVID-19 ; Health Personnel
    Language English
    Publishing date 2022-08-31
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 392299-6
    ISSN 1873-7714 ; 0163-8343
    ISSN (online) 1873-7714
    ISSN 0163-8343
    DOI 10.1016/j.genhosppsych.2022.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Biopsychosocial aspects of bereavement

    Zisook, Sidney

    (Progress in psychiatry series ; [8])

    1987  

    Author's details ed. by Sidney Zisook
    Series title Progress in psychiatry series ; [8]
    Collection
    Keywords Adaptation, Psychological ; Grief ; Neurobiology ; Social Adjustment ; Todesfall ; Psychologie
    Subject Mensch ; Sterbefall ; Trauerfall
    Size XII, 189 S. : graph. Darst.
    Publisher American Psychiatric Pr
    Publishing place Washington, DC
    Publishing country United States
    Document type Book
    HBZ-ID HT003221632
    ISBN 0-88048-135-8 ; 978-0-88048-135-9
    Database Catalogue ZB MED Medicine, Health

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