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  1. Article: The Effect of Water Column Resonance on the Spectra of Secondary Microseism P Waves

    Meschede, Matthias / Stutzmann, Éléonore / Farra, Véronique / Schimmel, Martin / Ardhuin, Fabrice

    Journal of geophysical research. 2017 Oct., v. 122, no. 10

    2017  

    Abstract: We compile and analyze a data set of secondary microseismic P wave spectra that were observed ... by North American seismic arrays. Two distinct frequency bands, 0.13–0.15 Hz and 0.19–0.21 Hz, with enhanced P ... able to reproduce amplitude and shape of the observed spectra, but only if P wave resonance ...

    Abstract We compile and analyze a data set of secondary microseismic P wave spectra that were observed by North American seismic arrays. Two distinct frequency bands, 0.13–0.15 Hz and 0.19–0.21 Hz, with enhanced P wave energy characterize the data set. Cluster analysis allows to classify the spectra and to associate typical spectral shapes with geographical regions: Low‐frequency‐dominated spectra (0.13–0.15 Hz) are mostly detected in shallower regions of the North Atlantic and the South Pacific, as well as along the Central and South American Pacific coast. High‐frequency‐dominated spectra (0.19–0.21 Hz) are mostly detected in deeper regions of the northwestern Pacific and the South Pacific. For a selected subset of high‐quality sources, we compute synthetic spectra from an ocean wave hindcast. These synthetic spectra are able to reproduce amplitude and shape of the observed spectra, but only if P wave resonance in the water column at the source site is included in the model. Our data sets therefore indicate that the spectral peaks at 0.13–0.15 Hz and 0.19–0.21 Hz correspond to the first and second harmonics of P wave resonance in the water column that occur in shallower ocean depths (<3,000 m) and in the deep ocean (∼5,000 m), respectively. This article demonstrates the important effect of water column resonance on the amplitude and frequency of P waves that are generated by secondary microseisms and that the amplitude of high‐quality sources can be predicted from ocean wave hindcasts within a factor of 0.4–6.
    Keywords cluster analysis ; coasts ; data collection ; geophysics ; models ; research ; water power
    Language English
    Dates of publication 2017-10
    Size p. 8121-8142.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ISSN 2169-9313
    DOI 10.1002/2017JB014014
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: The Sustainable Development Goals in Scientific Literature

    Christine Meschede

    Sustainability, Vol 12, Iss 4461, p

    A Bibliometric Overview at the Meta-Level

    2020  Volume 4461

    Abstract: In 2015, the UN adopted the Sustainable Development Goals (SDGs), addressing social, environmental, and economic targets. Global partnerships, transnational, and interdisciplinary research are essential for achieving progress towards the SDGs. This study ...

    Abstract In 2015, the UN adopted the Sustainable Development Goals (SDGs), addressing social, environmental, and economic targets. Global partnerships, transnational, and interdisciplinary research are essential for achieving progress towards the SDGs. This study analyzes 4593 research articles at the meta-level, explicitly referring to the SDGs. This a comparably small amount of research items directly addressing the goals. However, comparisons with existing approaches using different queries are possible. Research that links to the SDGs through its title, keywords, or abstract facilitates knowledge sharing on the goals as it is easier to identify relevant work. Using scientometric means, we assessed the corresponding sources, research areas, affiliated countries, thematic foci, and the availability of funding acknowledgments. The results are useful for identifying research gaps and potential collaboration possibilities. The outcomes suggest that most research referring to the SDGs comes from the research areas Life Sciences & Biomedicine and Social Sciences. The most predominant SDG among the analyzed research articles is SDG 3 (“good health and well-being”). A relatively high share of open access articles contributes to the idea of knowledge sharing for the SDGs. Nearly 37% of all articles count as international publications, i.e., as being co-authored by authors from affiliations of multiple countries.
    Keywords sustainable development goals ; bibliometric study ; multidisciplinary research ; transnational cooperation ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 001
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Does structured obstetric management play a role in the delivery mode and neonatal outcome of twin pregnancies?

    Ge, Isabell / Meschede, Julia / Juhasz-Boess, Ingolf / Kunze, Mirjam / Markfeld-Erol, Filiz

    Archives of gynecology and obstetrics

    2023  Volume 309, Issue 4, Page(s) 1441–1452

    Abstract: ... cesarean deliveries (44.0% vs. 63.5%, p < 0.0001) and higher rates of vaginal deliveries (68% vs. 52.4%, p ...

    Abstract Purpose: While the optimal delivery method of twin pregnancies is debated, the rate of cesarean deliveries is increasing. This retrospective study evaluates delivery methods and neonatal outcome of twin pregnancies during two time periods and aims to identify predictive factors for the delivery outcome.
    Methods: 553 twin pregnancies were identified in the institutional database of the University Women's Hospital Freiburg, Germany. 230 and 323 deliveries occurred in period I (2009-2014) and period II (2015-2021), respectively. Cesarean births due to non-vertex position of the first fetus were excluded. In period II, the management of twin pregnancies was reviewed; adjusted and systematic training with standardized procedures was implemented.
    Results: Period II showed significantly lower rates of planned cesarean deliveries (44.0% vs. 63.5%, p < 0.0001) and higher rates of vaginal deliveries (68% vs. 52.4%, p = 0.02). Independent risk factors for primary cesarean delivery were period I, maternal age > 40 years, nulliparity, a history with a previous cesarean, gestational age < 37 completed weeks, monochorionicity and increasing birth weight difference (per 100 g or > 20%). Predictive factors for successful vaginal delivery were previous vaginal delivery gestational age between 34 and 36 weeks and vertex/vertex presentation of the fetuses. The neonatal outcomes of period I and II were not significantly different, but planned cesareans in general were associated with increased admission rates to the neonatal intensive care units. Inter-twin interval had no significant impact on neonatal outcome.
    Conclusion: Structured regular training of obstetrical procedures may significantly reduce high cesarean rates and increase the benefit-risk ratio of vaginal deliveries.
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; Infant ; Adult ; Pregnancy, Twin ; Retrospective Studies ; Delivery, Obstetric/methods ; Cesarean Section ; Parity ; Pregnancy Outcome/epidemiology
    Language English
    Publishing date 2023-04-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-023-07040-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Including Citizen Participation Formats for Drafting and Implementing Local Sustainable Development Strategies

    Christine Meschede / Agnes Mainka

    Urban Science, Vol 4, Iss 1, p

    2020  Volume 13

    Abstract: Since the publication of the United Nations’ Sustainable Development Goals, governance for sustainable development has grown and several national, regional and local sustainable development strategies have been adopted. A sustainable development strategy ...

    Abstract Since the publication of the United Nations’ Sustainable Development Goals, governance for sustainable development has grown and several national, regional and local sustainable development strategies have been adopted. A sustainable development strategy can serve as a political control instrument and management tool. For the development and implementation of such a strategy at the local level, municipalities might use citizen participation approaches. There exist manifold ways of consulting civil society, representing different levels of decision-making power. The analysis of this article is divided into two parts. First, we report on a case study of the pilot project “Global Sustainable Municipalities” located in North Rhine-Westphalia, Germany and assess the current status of the use of citizen participation formats for adopting a local sustainable development strategy. Second, we developed a model of citizen participation approaches during different phases of adopting a sustainable development strategy. The purpose of this model is to assess the potential decision-making power of citizens during the phases and to help municipalities to get an orientation on participation possibilities. The results show that most municipalities count on participation mainly in the implementation phase of the strategy, less during developing it. Our model, however, demonstrates participation possibilities for each of the phases.
    Keywords citizen participation ; decision-making ; germany ; smart sustainable municipalities ; sustainable development goals ; sustainable development strategy ; Geography. Anthropology. Recreation ; G ; Social Sciences ; H
    Subject code 710
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: New light on photoreceptor renewal.

    Burgoyne, T / Meschede, I P / Futter, C E

    Cell cycle (Georgetown, Tex.)

    2016  Volume 15, Issue 11, Page(s) 1389–1390

    MeSH term(s) Cell Membrane ; Humans ; Light ; Photoreceptor Cells, Vertebrate/physiology
    Language English
    Publishing date 2016-05-06
    Publishing country United States
    Document type Editorial
    ZDB-ID 2146183-1
    ISSN 1551-4005 ; 1538-4101 ; 1554-8627
    ISSN (online) 1551-4005
    ISSN 1538-4101 ; 1554-8627
    DOI 10.1080/15384101.2016.1164579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Reduction of

    Meschede, J / Holtrup, S / Deitmer, R / Mesu, A P / Kraft, C

    Heliyon

    2021  Volume 7, Issue 4, Page(s) e06714

    Abstract: ... ...

    Abstract Salmonella
    Language English
    Publishing date 2021-04-14
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2021.e06714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Conference proceedings: Interventionelle bronchoskopische Verfahren in der Diagnostik der Sarkoidose

    Terschluse, C / Agarwal, P / Feineis, M / Fähndrich, S / Meschede, W / Müller-Quernheim, J / Stolz, D / Frye, B

    Pneumologie

    2023  Volume 77, Issue S 01

    Event/congress 63. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V., Düsseldorf, 2023-03-29
    Language German
    Publishing date 2023-03-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 607630-0
    ISSN 1438-8790 ; 0934-8387
    ISSN (online) 1438-8790
    ISSN 0934-8387
    DOI 10.1055/s-0043-1761103
    Database Thieme publisher's database

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  8. Article ; Online: Chronically shortened rod outer segments accompany photoreceptor cell death in Choroideremia.

    Meschede, Ingrid P / Burgoyne, Thomas / Tolmachova, Tanya / Seabra, Miguel C / Futter, Clare E

    PloS one

    2020  Volume 15, Issue 11, Page(s) e0242284

    Abstract: X-linked choroideremia (CHM) is a disease characterized by gradual retinal degeneration caused by loss of the Rab Escort Protein, REP1. Despite partial compensation by REP2 the disease is characterized by prenylation defects in multiple members of the ... ...

    Abstract X-linked choroideremia (CHM) is a disease characterized by gradual retinal degeneration caused by loss of the Rab Escort Protein, REP1. Despite partial compensation by REP2 the disease is characterized by prenylation defects in multiple members of the Rab protein family that are master regulators of membrane traffic. Remarkably, the eye is the only organ affected in CHM patients, possibly because of the huge membrane traffic burden of the post mitotic photoreceptors, which synthesise outer segments, and the adjacent retinal pigment epithelium that degrades the spent portions each day. In this study, we aimed to identify defects in membrane traffic that might lead to photoreceptor cell death in CHM. In a heterozygous null female mouse model of CHM (Chmnull/WT), degeneration of the photoreceptor layer was clearly evident from increased numbers of TUNEL positive cells compared to age matched controls, small numbers of cells exhibiting signs of mitochondrial stress and greatly increased microglial infiltration. However, most rod photoreceptors exhibited remarkably normal morphology with well-formed outer segments and no discernible accumulation of transport vesicles in the inner segment. The major evidence of membrane trafficking defects was a shortening of rod outer segments that was evident at 2 months of age but remained constant over the period during which the cells die. A decrease in rhodopsin density found in the outer segment may underlie the outer segment shortening but does not lead to rhodopsin accumulation in the inner segment. Our data argue against defects in rhodopsin transport or outer segment renewal as triggers of cell death in CHM.
    MeSH term(s) Adaptor Proteins, Signal Transducing/deficiency ; Adaptor Proteins, Signal Transducing/genetics ; Animals ; Apoptosis ; Choroideremia/metabolism ; Choroideremia/pathology ; Disease Models, Animal ; Female ; Mice ; Mice, Knockout ; Microscopy, Electron, Transmission ; Mitochondria/metabolism ; Photoreceptor Cells, Vertebrate/metabolism ; Photoreceptor Cells, Vertebrate/ultrastructure ; Rhodopsin/metabolism ; Rod Cell Outer Segment/metabolism
    Chemical Substances Adaptor Proteins, Signal Transducing ; Chm protein, mouse ; Rhodopsin (9009-81-8)
    Language English
    Publishing date 2020-11-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0242284
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Reduction of Salmonella prevalence at slaughter in Lawsonia intracellularis co-infected swine herds by Enterisol® Ileitis vaccination

    J. Meschede / S. Holtrup / R. Deitmer / A.P. Mesu / C. Kraft

    Heliyon, Vol 7, Iss 4, Pp e06714- (2021)

    2021  

    Abstract: Salmonella spp. remains a wide-spread pathogen among pig herds and its control has major impact on food borne Salmonella infections in humans. The objective of the study was to investigate the influence of an Enterisol® Ileitis vaccination on Salmonella ... ...

    Abstract Salmonella spp. remains a wide-spread pathogen among pig herds and its control has major impact on food borne Salmonella infections in humans. The objective of the study was to investigate the influence of an Enterisol® Ileitis vaccination on Salmonella seroprevalence in Lawsonia intracellularis (L. intracellularis) and Salmonella spp. co-infected pig herds under field conditions.This study compared vaccinated and non-vaccinated pigs of consecutive piglet batches, housed on four different finishing units. Prior to study start, endemic field infections of L. intracellularis and Salmonella spp. were confirmed by serology in the nursery and in all finishing units. Field infection of L. intracellularis occurred at the middle of the nursery phase.In total twenty-five batches of finishing pigs were included in the study, pigs were investigated for four (non-vaccinated group, n = 9) or six months (vaccinated group, n = 16). The primary outcome parameter was Salmonella serology (antibody titers) at the end of fattening. Secondary parameters comprised serology for L. intracellularis and performance parameters, including average daily weight gain (g), duration of fattening period (days), feed conversion (kg/kg) and mortality (%).A total of 709 blood samples were assessed, deriving from vaccinated (n = 439) and non-vaccinated finishing pigs (n = 270). Evaluation of the antibody titers demonstrated that vaccination significantly reduced the Salmonella seroprevalence in the finishing pigs on all four farms. The average OD% values were reduced from 32.7% to 13.4% in addition to a reduced variability in the vaccinated pigs compared to the control group. The Salmonella category of all finishing farms improved by at least one category in accordance with the German Salmonella monitoring program. In addition, vaccination had a positive tendency on the average daily weight gain, fattening duration and reduced mortality.In conclusion, this study demonstrates that vaccination with Enterisol® Ileitis has a positive and direct impact on reduction of Salmonella infection in co-infected herds.
    Keywords Salmonella infection ; Co-infection ; Lawsonia intracellularis ; QS scheme ; Vaccination ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 630
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Synaptic and intrinsic mechanisms underlying development of cortical direction selectivity.

    Roy, Arani / Osik, Jason J / Meschede-Krasa, Benyamin / Alford, Wesley T / Leman, Daniel P / Van Hooser, Stephen D

    eLife

    2020  Volume 9

    Abstract: Modifications of synaptic inputs and cell-intrinsic properties both contribute to neuronal plasticity and development. To better understand these mechanisms, we undertook an intracellular analysis of the development of direction selectivity in the ferret ...

    Abstract Modifications of synaptic inputs and cell-intrinsic properties both contribute to neuronal plasticity and development. To better understand these mechanisms, we undertook an intracellular analysis of the development of direction selectivity in the ferret visual cortex, which occurs rapidly over a few days after eye opening. We found strong evidence of developmental changes in linear spatiotemporal receptive fields of simple cells, implying alterations in circuit inputs. Further, this receptive field plasticity was accompanied by increases in near-spike-threshold excitability and input-output gain that resulted in dramatically increased spiking responses in the experienced state. Increases in subthreshold membrane responses induced by the receptive field plasticity and the increased input-output spiking gain were both necessary to explain the elevated firing rates in experienced ferrets. These results demonstrate that cortical direction selectivity develops through a combination of plasticity in inputs and in cell-intrinsic properties.
    MeSH term(s) Animals ; Female ; Ferrets/growth & development ; Ferrets/physiology ; Neuronal Plasticity/physiology ; Visual Cortex/growth & development ; Visual Cortex/physiology
    Language English
    Publishing date 2020-07-23
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.58509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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