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  1. Book: Stem cell-based therapy for neurodegenerative diseases

    Han, Fabin / Lu, Pengzhe (Paul)

    (Advances in experimental medicine and biology ; 1266)

    2020  

    Author's details Fabin Han, Pengzhe (Paul) Lu editors
    Series title Advances in experimental medicine and biology ; 1266
    Collection
    Keywords Stem cells ; Neurosciences ; Neurology
    Subject code 571.6
    Language English
    Size V, 145 Seiten, Illustrationen
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book
    HBZ-ID HT020632752
    ISBN 978-981-15-4369-2 ; 9789811543708 ; 981-15-4369-0 ; 9811543704
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3192 -1266- not available for loan Zeitschriften-Lesesaal

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  2. Article: Combining neural progenitor cell transplant and rehabilitation for enhanced recovery after cervical spinal cord injury.

    Freria, Camila M / Lu, Paul

    Neural regeneration research

    2023  Volume 19, Issue 7, Page(s) 1433–1434

    Language English
    Publishing date 2023-11-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/1673-5374.387993
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Lithium, sodium and potassium enolate aggregates and monomers: syntheses and structures.

    Davison, Nathan / Hemingway, Jack M / Waddell, Paul G / Lu, Erli

    Dalton transactions (Cambridge, England : 2003)

    2024  Volume 53, Issue 10, Page(s) 4719–4728

    Abstract: ... In ... ...

    Abstract In this
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d4dt00211c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Identifying Vulnerabilities to NSAID Adverse Events in the U.S. Population: An Analysis of Preexisting Conditions and Sex.

    Rogers, Paul / Wang, Dong / Lu, Zhiyuan / Lyn-Cook, Beverly

    Journal of women's health (2002)

    2024  

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1139774-3
    ISSN 1931-843X ; 1059-7115 ; 1540-9996
    ISSN (online) 1931-843X
    ISSN 1059-7115 ; 1540-9996
    DOI 10.1089/jwh.2023.1039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3584: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Reduction of K

    Davison, Nathan / Waddell, Paul G / Lu, Erli

    Journal of the American Chemical Society

    2023  Volume 145, Issue 31, Page(s) 17007–17012

    Abstract: Given their very negative redox potential (e.g., ... ...

    Abstract Given their very negative redox potential (e.g., Li
    Language English
    Publishing date 2023-07-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c06066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  6. Article ; Online: Efficient Oxidative Decomposition of Jet-Fuel

    Biswas, Souvick / Paul, Dababrata / Dias, Nureshan / Lu, Wenchao / Ahmed, Musahid / Pantoya, Michelle L / Kaiser, Ralf I

    The journal of physical chemistry. A

    2024  Volume 128, Issue 9, Page(s) 1665–1684

    Abstract: The oxidation of gas- ... ...

    Abstract The oxidation of gas-phase
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.3c08125
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Editorial: Endocrinological factors for autism: prenatal biomarkers, early diagnosis and symptom treatment.

    Liang, Yujie / Zhong, Liyan / Lu, Jianping / Yao, Paul

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1298381

    MeSH term(s) Pregnancy ; Female ; Humans ; Autistic Disorder/diagnosis ; Autistic Disorder/therapy ; Autism Spectrum Disorder/diagnosis ; Autism Spectrum Disorder/therapy ; Vitamins ; Biomarkers ; Early Diagnosis
    Chemical Substances Vitamins ; Biomarkers
    Language English
    Publishing date 2023-11-09
    Publishing country Switzerland
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1298381
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Engineering, applications, and future perspectives of GPCR-based genetically encoded fluorescent indicators for neuromodulators.

    Rohner, Valentin Lu / Lamothe-Molina, Paul J / Patriarchi, Tommaso

    Journal of neurochemistry

    2024  Volume 168, Issue 3, Page(s) 163–184

    Abstract: This review explores the evolving landscape of G-protein-coupled receptor (GPCR)-based genetically encoded fluorescent indicators (GEFIs), with a focus on their development, structural components, engineering strategies, and applications. We highlight ... ...

    Abstract This review explores the evolving landscape of G-protein-coupled receptor (GPCR)-based genetically encoded fluorescent indicators (GEFIs), with a focus on their development, structural components, engineering strategies, and applications. We highlight the unique features of this indicator class, emphasizing the importance of both the sensing domain (GPCR structure and activation mechanism) and the reporting domain (circularly permuted fluorescent protein (cpFP) structure and fluorescence modulation). Further, we discuss indicator engineering approaches, including the selection of suitable cpFPs and expression systems. Additionally, we showcase the diversity and flexibility of their application by presenting a summary of studies where such indicators were used. Along with all the advantages, we also focus on the current limitations as well as common misconceptions that arise when using these indicators. Finally, we discuss future directions in indicator engineering, including strategies for screening with increased throughput, optimization of the ligand-binding properties, structural insights, and spectral diversity.
    MeSH term(s) Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism ; Cell Communication ; Fluorescence ; Coloring Agents ; Neurotransmitter Agents/metabolism
    Chemical Substances Receptors, G-Protein-Coupled ; Coloring Agents ; Neurotransmitter Agents
    Language English
    Publishing date 2024-01-30
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 80158-6
    ISSN 1471-4159 ; 0022-3042 ; 1474-1644
    ISSN (online) 1471-4159
    ISSN 0022-3042 ; 1474-1644
    DOI 10.1111/jnc.16045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.170: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Neural mechanisms of respiratory interoception.

    Chan, Pei-Ying Sarah / Lee, Lu-Yuan / Davenport, Paul W

    Autonomic neuroscience : basic & clinical

    2024  Volume 253, Page(s) 103181

    Abstract: Respiratory interoception is one of the internal bodily systems that is comprised of different types of somatic and visceral sensations elicited by different patterns of afferent input and respiratory motor drive mediating multiple respiratory modalities. ...

    Abstract Respiratory interoception is one of the internal bodily systems that is comprised of different types of somatic and visceral sensations elicited by different patterns of afferent input and respiratory motor drive mediating multiple respiratory modalities. Respiratory interoception is a complex system, having multiple afferents grouped into afferent clusters and projecting into both discriminative and affective centers that are directly related to the behavioral assessment of breathing. The multi-afferent system provides a spectrum of input that result in the ability to interpret the different types of respiratory interceptive sensations. This can result in a response, commonly reported as breathlessness or dyspnea. Dyspnea can be differentiated into specific modalities. These respiratory sensory modalities lead to a general sensation of an Urge-to-Breathe, driven by a need to compensate for the modulation of ventilation that has occurred due to factors that have affected breathing. The multiafferent system for respiratory interoception can also lead to interpretation of the sensory signals resulting in respiratory related sensory experiences, including the Urge-to-Cough and Urge-to-Swallow. These behaviors are modalities that can be driven through the differentiation and integration of multiple afferent input into the respiratory neural comparator. Respiratory sensations require neural somatic and visceral interoceptive elements that include gated attention and detection leading to respiratory modality discrimination with subsequent cognitive decision and behavioral compensation. Studies of brain areas mediating cortical and subcortical respiratory sensory pathways are summarized and used to develop a model of an integrated respiratory neural network mediating respiratory interoception.
    Language English
    Publishing date 2024-04-25
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2020105-9
    ISSN 1872-7484 ; 1566-0702
    ISSN (online) 1872-7484
    ISSN 1566-0702
    DOI 10.1016/j.autneu.2024.103181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1533: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Book ; Online: Instance-based Explanations for Gradient Boosting Machine Predictions with AXIL Weights

    Geertsema, Paul / Lu, Helen

    2023  

    Abstract: We show that regression predictions from linear and tree-based models can be represented as linear combinations of target instances in the training data. This also holds for models constructed as ensembles of trees, including Random Forests and Gradient ... ...

    Abstract We show that regression predictions from linear and tree-based models can be represented as linear combinations of target instances in the training data. This also holds for models constructed as ensembles of trees, including Random Forests and Gradient Boosting Machines. The weights used in these linear combinations are measures of instance importance, complementing existing measures of feature importance, such as SHAP and LIME. We refer to these measures as AXIL weights (Additive eXplanations with Instance Loadings). Since AXIL weights are additive across instances, they offer both local and global explanations. Our work contributes to the broader effort to make machine learning predictions more interpretable and explainable.
    Keywords Computer Science - Machine Learning ; Computer Science - Artificial Intelligence ; K.3.2
    Publishing date 2023-01-04
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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