LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 151

Search options

  1. Article ; Online: Confronting the Negative Impact of Cigarette Smoking on Cancer Surgery.

    Choe, Se-In / Finley, Christian

    Current oncology (Toronto, Ont.)

    2022  Volume 29, Issue 8, Page(s) 5869–5874

    Abstract: Smoking is a common health risk behavior that has substantial effects on perioperative risk and postoperative surgical outcomes. Current smoking is clearly linked to an increased risk of perioperative cardiovascular, pulmonary and wound healing ... ...

    Abstract Smoking is a common health risk behavior that has substantial effects on perioperative risk and postoperative surgical outcomes. Current smoking is clearly linked to an increased risk of perioperative cardiovascular, pulmonary and wound healing complications. Accumulating evidence indicates that smoking cessation can reduce the higher perioperative complication risk that is observed in current smokers. In addition, continued smoking has a negative impact on the overall prognosis of cancer patients. Smoking cessation, on the other hand, can improve long-term outcomes after surgery. Smoking cessation services should be implemented in a comprehensive programmatic manner to ensure that all patients gain access to evidence-based care. Although the benefits of abstinence increase in proportion to the length of cessation, cessation should be recommended regardless of timing prior to surgery.
    MeSH term(s) Cigarette Smoking ; Humans ; Neoplasms/etiology ; Neoplasms/surgery ; Postoperative Period ; Prognosis ; Smoking Cessation
    Language English
    Publishing date 2022-08-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1236972-x
    ISSN 1718-7729 ; 1198-0052
    ISSN (online) 1718-7729
    ISSN 1198-0052
    DOI 10.3390/curroncol29080463
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: The effect of surgeon volume on procedure selection in non-small cell lung cancer surgeries.

    Finley, Christian

    The Journal of thoracic and cardiovascular surgery

    2016  Volume 151, Issue 4, Page(s) 1219

    MeSH term(s) Carcinoma, Non-Small-Cell Lung/surgery ; Delivery of Health Care/trends ; Female ; Hospitals, High-Volume/trends ; Hospitals, Low-Volume/trends ; Humans ; Lung Neoplasms/surgery ; Male ; Patient Selection ; Pneumonectomy/trends ; Surgeons/trends
    Language English
    Publishing date 2016-04
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 3104-5
    ISSN 1097-685X ; 0022-5223
    ISSN (online) 1097-685X
    ISSN 0022-5223
    DOI 10.1016/j.jtcvs.2016.01.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Current and Future Treatment Options in the Management of Stage III NSCLC.

    Li, Yuchen / Juergens, Rosalyn Anne / Finley, Christian / Swaminath, Anand

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2023  Volume 18, Issue 11, Page(s) 1478–1491

    Abstract: For much of the past two decades, the treatment options for patients with stage III NSCLC were mostly stagnant. In the past 5 years, ongoing innovations have dovetailed alongside advances in biomarker testing, novel therapeutics, precision surgery, and ... ...

    Abstract For much of the past two decades, the treatment options for patients with stage III NSCLC were mostly stagnant. In the past 5 years, ongoing innovations have dovetailed alongside advances in biomarker testing, novel therapeutics, precision surgery, and radiotherapy, all of which are leading to an increase in more personalized option for the treatment. This review article will focus on several completed and ongoing initiatives involving treatment of patients with stage III NSCLC. First, it will tackle the progress made in curative treatment of unresectable stage III NSCLC, starting with PACIFIC, and branching out into topics such as concurrent immunotherapy and chemoradiation, intensification of consolidative immunotherapy, dual immunotherapy consolidation, and a reflection on those subpopulations that may not benefit from consolidative immunotherapy. Second, there will be discussion of novel strategies in the setting of resectable stage III disease, most notably neoadjuvant therapy using combined chemoimmunotherapy and immunotherapy alone before surgical resection. Third, it will delve into recent data evaluating adjuvant immunotherapy for resectable stage III NSCLC, including adjuvant targeted therapy (for those harboring driver mutations) and postoperative radiotherapy. Finally, a look to future trials/initiatives will be interspersed throughout the review, to reveal the ongoing efforts being made to continue to improve outcomes in this group of patients.
    MeSH term(s) Humans ; Lung Neoplasms/pathology ; Neoplasm Staging ; Carcinoma, Non-Small-Cell Lung/pathology ; Combined Modality Therapy ; Neoadjuvant Therapy ; Immunotherapy
    Language English
    Publishing date 2023-08-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2023.08.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: When is the burden of responsibility over for the surgeon?

    Finley, Christian J

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2016  Volume 49, Issue 2, Page(s) 594–595

    MeSH term(s) Hospital Mortality ; Humans ; Surgeons
    Language English
    Publishing date 2016-02
    Publishing country Germany
    Document type Comment ; Editorial
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezv160
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Book: Christian faith and the contemporary arts

    Eversole, Finley

    1962  

    Author's details ed. by Finley Eversole
    Keywords Art and religion ; Art, Modern ; Christian civilization ; Music/Religious aspects
    Language English
    Size 255 S, Ill
    Publisher Abingdon Pr
    Publishing place New York u.a.
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

  6. Article ; Online: Pan-Canadian colorectal cancer surgery data: an opportunity for reflection and improvement.

    Moloo, Husein / Lacaille-Ranger, Ariane / MacLean, Anthony / Finley, Christian

    Canadian journal of surgery. Journal canadien de chirurgie

    2022  Volume 65, Issue 6, Page(s) E735–E738

    Abstract: Variation in data provides an opportunity for health care providers to assess how patient care can be improved. Pan-Canadian colorectal cancer data show that, although long-term survival is similar among provinces, differences exist in other important ... ...

    Abstract Variation in data provides an opportunity for health care providers to assess how patient care can be improved. Pan-Canadian colorectal cancer data show that, although long-term survival is similar among provinces, differences exist in other important aspects of care: length of stay, minimally invasive approach, readmission, and short-term mortality. Examining variation among stakeholders involved with colorectal cancer allows the opportunity to reflect on and optimize care.
    MeSH term(s) Humans ; Canada ; Digestive System Surgical Procedures ; Colorectal Neoplasms/surgery ; Length of Stay ; Minimally Invasive Surgical Procedures ; Retrospective Studies ; Postoperative Complications
    Language English
    Publishing date 2022-11-02
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 410651-9
    ISSN 1488-2310 ; 0008-428X
    ISSN (online) 1488-2310
    ISSN 0008-428X
    DOI 10.1503/cjs.000621
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: A trans-Canadian positive deviance seminar for paraesophageal hernia surgery: Reporting national postoperative outcomes and consensus recommendations.

    Tankel, James / Safieddine, Najib / Malthaner, Rick / French, Danny / Johnston, Brian / Finley, Christian / Darling, Gail / Ferri, Lorenzo / Seely, Andrew / Gowing, Stephen

    World journal of surgery

    2024  Volume 48, Issue 3, Page(s) 673–680

    Abstract: Background: The incidence of adverse events (AEs) and length of stay (LOS) varies significantly following paraesophageal hernia surgery. We performed a Canadian multicenter positive deviance (PD) seminar to review individual center and national level ... ...

    Abstract Background: The incidence of adverse events (AEs) and length of stay (LOS) varies significantly following paraesophageal hernia surgery. We performed a Canadian multicenter positive deviance (PD) seminar to review individual center and national level data and establish holistic perioperative practice recommendations.
    Methods: A national virtual PD seminar was performed in October 2021. Recent best evidence focusing on AEs and LOS was presented. Subsequently, anonymized center-level AE and LOS data collected between 01/2017 and 01/2021 from a prospective, web-based database that tracks postoperative outcomes was presented. The top two performing centers with regards to these metrics were chosen and surgeons from these hospitals discussed elements of their treatment pathways that contributed to these outcomes. Consensus recommendations were then identified with participants independently rating their level of agreement.
    Results: Twenty-eight surgeons form 8 centers took part in the seminar across 5 Canadian provinces. Of the 680 included patients included, Clavien-Dindo grade I and II/III/IV/V complications occurred in 121/39/12/2 patients (17.8%/5.7%/1.8%/0.3%). Respiratory complications were the most common (effusion 12/680, 1.7% and pneumonia 9/680, 1.3%). Esophageal and gastric perforation occurred in 7 and 4/680, (1.0% and 0.6% respectively). Median LOS varied significantly between institutions (1 day, range 1-3 vs. 7 days, 3-8, p < 0.001). A strong level of agreement was achieved for 10/12 of the consensus statements generated.
    Conclusion: PD seminars provide a supportive forum for centers to review best evidence and experience and generate recommendations based on expert opinion. Further research is ongoing to determine if this approach effectively accomplishes this objective.
    MeSH term(s) Humans ; Hernia, Hiatal/surgery ; Hernia, Hiatal/complications ; Prospective Studies ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Canada ; Length of Stay ; Laparoscopy/adverse effects
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1002/wjs.12087
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Users' Guide to the Surgical Literature: How to Appraise ERAS Guidelines.

    Uhlman, Kathryn / Sardiwalla, Yaeesh / Chin, Brian / Murphy, Jessica / Finley, Christian / Thoma, Achilles

    Journal of cardiothoracic and vascular anesthesia

    2022  Volume 36, Issue 8 Pt B, Page(s) 2857–2863

    Language English
    Publishing date 2022-05-05
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2022.04.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: The dependence of timing jitter of superconducting nanowire single-photon detectors on the multi-layer sample design and slew rate.

    Flaschmann, Rasmus / Zugliani, Lucio / Schmid, Christian / Spedicato, Simone / Strohauer, Stefan / Wietschorke, Fabian / Flassig, Fabian / Finley, Jonathan J / Müller, Kai

    Nanoscale

    2023  Volume 15, Issue 3, Page(s) 1086–1091

    Abstract: We investigated the timing jitter of superconducting nanowire single-photon detectors (SNSPDs) and found a strong dependence on the detector response. By varying the multi-layer structure, we observed changes in pulse shape which are attributed to ... ...

    Abstract We investigated the timing jitter of superconducting nanowire single-photon detectors (SNSPDs) and found a strong dependence on the detector response. By varying the multi-layer structure, we observed changes in pulse shape which are attributed to capacitive behaviour affecting the pulse heights, rise times and consequently timing jitter. Moreover, we developed a technique to predict the timing jitter of a single device within certain limits by capturing only a single detector pulse, eliminating the need for detailed jitter measurement using a pulsed laser when a rough estimate of the timing jitter is sufficient.
    Language English
    Publishing date 2023-01-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d2nr04494c
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Evaluation of Factors Associated With Unmet Needs in Adult Cancer Survivors in Canada.

    Shakeel, Saad / Tung, Jasmine / Rahal, Rami / Finley, Christian

    JAMA network open

    2020  Volume 3, Issue 3, Page(s) e200506

    Abstract: Importance: Understanding the challenges faced by an increasing number of cancer survivors can guide the development and implementation of effective survivorship care models.: Objective: To identify the physical, emotional, and practical concerns and ...

    Abstract Importance: Understanding the challenges faced by an increasing number of cancer survivors can guide the development and implementation of effective survivorship care models.
    Objective: To identify the physical, emotional, and practical concerns and associated unmet needs reported by cancer survivors.
    Design, setting, and participants: This cross-sectional survey study obtained data from the Experiences of Cancer Patients in Transitions Study of the Canadian Partnership Against Cancer, in collaboration with cancer agencies in the 10 Canadian provinces, that was disseminated in 2016. This analysis included only adult survivors aged 30 years or older who underwent chemotherapy, radiation therapy, surgical treatment, or a combination of these therapies for breast, prostate, colorectal, melanoma, or hematological cancer within the past 1 to 3 years. Data synthesis and quality assessment were conducted in 2017. Data analysis was completed in July 2019.
    Main outcomes and measures: The outcomes were the (1) quantification of the magnitude and multiplicity of the physical, emotional, and practical concerns of adult survivors of breast, colorectal, prostate, melanoma, or hematological cancer; (2) exploration of the magnitude of associated unmet needs; and (3) identification of patient-, treatment-, and cancer-specific factors associated with the reporting of unmet needs.
    Results: Overall, 10 717 adult respondents were included (5660 [53%] female and 6367 [60%] aged ≥65 years). The median number of concerns per respondent was 6 (interquartile range [IQR], 3-10). Among respondents with concerns, help was sought for a median of 2 (IQR, 0-4) concerns. Unmet needs were reported for a median of 4 (IQR, 2-7) concerns. Emotional concerns were reported by 8330 respondents (78%), physical concerns by 9236 respondents (86%), and practical concerns by 4668 respondents (44%). At least 1 unmet need was reported by 7033 survivors (84%) with emotional concerns, 7475 (81%) with physical concerns, and 3459 (74%) with practical concerns. Age, sex, annual income, marital status, geographic location, language, and treatment type were significant factors associated with unmet needs. Survivors of melanoma cancer had a significantly higher likelihood of reporting unmet emotional needs (odds ratio [OR], 1.75; 95% CI, 1.17-2.61; P = .01), whereas survivors of prostate (OR, 0.60; 95% CI, 0.43-0.84; P < .001) and hematological (OR, 0.70; 95% CI, 0.50-0.99; P = .04) cancers were significantly less likely to report unmet needs for physical concerns when compared with breast cancer survivors. Involvement of the general practitioner combined with the oncologist in providing care was associated with a significantly lower likelihood of reporting unmet emotional (OR, 0.78; 95% CI, 0.62-1.00; P = .05) and practical (OR, 0.72; 95% CI, 0.55-0.94; P = .01) needs.
    Conclusions and relevance: The extent of unmet needs among cancer survivors found in this study suggests the need for enhancements in survivorship care, including better awareness of the realities of survivorship, earlier interventions for emerging concerns among survivors, and greater integration of cancer programs and primary care for more seamless transitions.
    MeSH term(s) Adult ; Aged ; Canada ; Cancer Survivors/psychology ; Cross-Sectional Studies ; Emotions ; Female ; Health Services Needs and Demand ; Humans ; Male ; Middle Aged ; Needs Assessment ; Neoplasms/complications ; Neoplasms/psychology ; Neoplasms/therapy ; Quality of Life ; Surveys and Questionnaires
    Language English
    Publishing date 2020-03-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2020.0506
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top