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Article ; Online: A retrospective study on the effects of dry period length on milk yield and postpartum health in Holstein dairy cows.

Koyama, Takeshi / Tanigawa, Tamako / Sugimoto, Masahito / Osaka, Ikuo

Animal science journal = Nihon chikusan Gakkaiho

2024 Volume 95, Issue 1, Page(s) e13912

Abstract: We retrospectively analyzed the effects of dry period length (DPL) on milk yield and postpartum health using 152 commercial dairy farm data, including 46,228 dairy cows in Hokkaido, Japan, and examined the optimal DPL. The DPL was divided into eight ... ...

Abstract	We retrospectively analyzed the effects of dry period length (DPL) on milk yield and postpartum health using 152 commercial dairy farm data, including 46,228 dairy cows in Hokkaido, Japan, and examined the optimal DPL. The DPL was divided into eight categories: ≤25, 26-35, 36-45, 46-55, 56-65 (reference), 66-75, 76-85, and ≥86 d. The total milk yields (the sum of milk yield during the 55 d before and the 305 d milk yield after calving) of cows with DPL of ≤55 d did not differ from the reference group. Cows with DPL of ≤55 d had lower odds ratios (OR) of a displaced abomasum (DA), ketosis, milk fever (MF), and abnormal milk fat-to-protein ratio but had higher puerperal fever (PF) and stillbirth ORs than the reference group. Cows with a DPL of 46-55 d had the lowest PF and stillbirth ORs among the short DPL categories. The extremely short (≤25 d) and long (≥86 d) DPL increased the ORs of mastitis and abnormal liner score of somatic cell counts (SCCs) compared with the reference group. We conclude that shortening DPL can reduce postpartum health problems without reducing milk yield and that the optimal DPL is 46-55 d.
MeSH term(s)	Pregnancy ; Female ; Cattle ; Animals ; Milk ; Lactation ; Retrospective Studies ; Stillbirth/veterinary ; Postpartum Period ; Milk Proteins ; Cattle Diseases/epidemiology
Chemical Substances	Milk Proteins
Language	English
Publishing date	2024-01-30
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2095161-9
ISSN	1740-0929 ; 1344-3941
ISSN (online)	1740-0929
ISSN	1344-3941
DOI	10.1111/asj.13912
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Quantum Chemical Study of the Cycloaddition Reaction of Tropone with 1,1-Diethoxyethene Catalyzed by B(C

Sakata, Ken / Suzuki, Sarina / Sugimoto, Tsubasa / Yoshikawa, Takeshi

ACS omega

2023 Volume 8, Issue 33, Page(s) 30410–30420

Abstract: Cycloaddition reaction of tropone with 1,1-diethoxyethene catalyzed by Lewis acid (LA), B( ... ...

Abstract	Cycloaddition reaction of tropone with 1,1-diethoxyethene catalyzed by Lewis acid (LA), B(C
Language	English
Publishing date	2023-08-08
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.3c03560
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Disappearance of Atypical Gastric Mucosal Bleeding due to Heyde's Syndrome after Transcatheter Aortic Valve Implantation.

Sugimoto, Shinya / Takamura, Takeshi

Case reports in gastroenterology

2022 Volume 16, Issue 1, Page(s) 165–170

Abstract: An 82-year-old man was admitted to our hospital due to dyspnea on exertion. Blood tests showed iron deficiency anemia, and echocardiography revealed severe aortic stenosis (AS). Considering the possibility of Heyde's syndrome, esophagogastroduodenoscopy ... ...

Abstract	An 82-year-old man was admitted to our hospital due to dyspnea on exertion. Blood tests showed iron deficiency anemia, and echocardiography revealed severe aortic stenosis (AS). Considering the possibility of Heyde's syndrome, esophagogastroduodenoscopy was performed to confirm the presence or absence of gastrointestinal angiodysplasia. Endoscopy revealed multiple sites of mucosal bleeding in the stomach without angiodysplasia or mucosal erosion. Although it was an atypical endoscopic finding, we diagnosed gastric mucosal bleeding associated with Heyde's syndrome. Since no atypical blood vessels could be found, endoscopic treatment was not performed, and only transcatheter aortic valve implantation (TAVI) for aortic valve stenosis was performed. TAVI immediately improved the dyspnea on exertion, and follow-up endoscopy 4 months after TAVI showed the disappearance of the multifocal mucosal bleeding in the stomach. Heyde's syndrome is characterized by AS, acquired deficiency or dysfunction of von Willebrand factor, and gastrointestinal angiodysplasia; however, the exact diagnostic criteria have not been established. This is a case of mucosal bleeding due to Heyde's syndrome, without the typical endoscopic image of angiodysplasia. Cardiologists and gastroenterologists need to consider the possibility of Heyde's syndrome in AS patients with atypical gastrointestinal bleeding on endoscopy.
Language	English
Publishing date	2022-03-28
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2440540-1
ISSN	1662-0631
ISSN	1662-0631
DOI	10.1159/000522640
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The lactate response to a second bout of exercise is not reduced in a concurrent lower-limb exercise program.

Tsukamoto, Hayato / Suga, Tadashi / Dora, Kento / Sugimoto, Takeshi / Tomoo, Keigo / Isaka, Tadao / Hashimoto, Takeshi

Scientific reports

2023 Volume 13, Issue 1, Page(s) 21337

Abstract: We aimed to evaluate the blood lactate level in response to two bouts of exercise. First, we hypothesized that blood lactate elevation in response to moderate-intensity aerobic exercise (MIAE) would be lower at the end of the second bout of MIAE than the ...

Abstract	We aimed to evaluate the blood lactate level in response to two bouts of exercise. First, we hypothesized that blood lactate elevation in response to moderate-intensity aerobic exercise (MIAE) would be lower at the end of the second bout of MIAE than the first bout of MIAE. In this context, we also hypothesized that lactate accumulation at the end of resistance exercise (RE) would be reduced if MIAE is performed before RE (i.e., concurrent exercise; CE). If so, we hypothesized that the order of the CE (i.e., RE + MIAE vs. MIAE + RE) influences blood lactate kinetics. To test the hypotheses, forty-three healthy men participated in three studies. In study 1, 20 men (age 21 ± 2 years) performed two bouts of a 20-min MIAE separated by a 20-min rest interval. In study 2, 11 men (age 22 ± 1 years) performed RE only and CE (MIAE + RE; AR
MeSH term(s)	Humans ; Male ; Young Adult ; Exercise/physiology ; Exercise Test ; Exercise Therapy ; Lactic Acid ; Lower Extremity ; Oxygen Consumption/physiology ; Cross-Over Studies
Chemical Substances	Lactic Acid (33X04XA5AT)
Language	English
Publishing date	2023-12-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-48670-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Investigating the Combined Effects of Mechanical Stress and Nutrition on Muscle Hypertrophic Signals Using Contractile 3D-Engineered Muscle (3D-EM).

Yi, Dong / Sugimoto, Takeshi / Matsumura, Teppei / Yokoyama, Sho / Fujisato, Toshia / Nakamura, Tomohiro / Hashimoto, Takeshi

Nutrients

2023 Volume 15, Issue 18

Abstract: Since 3D-EM closely resembles in vivo muscles, the aim of this study was to investigate the effects of exercise (electrical pulse stimulation (EPS)) and nutrition (maca), which contains triterpenes, on muscle hypertrophy by using 3D-EM for the first time. ...

Abstract	Since 3D-EM closely resembles in vivo muscles, the aim of this study was to investigate the effects of exercise (electrical pulse stimulation (EPS)) and nutrition (maca), which contains triterpenes, on muscle hypertrophy by using 3D-EM for the first time. The 3D-EM was composed of C2C12 cells and type 1 collagen gel, was differentiated for 14 days, and was divided into four groups: control, maca, EPS, and maca + EPS. The medium was replaced every two days before each EPS intervention, and the concentration of maca in the culture solution was 1 mg/mL. The intervention conditions of the EPS were 30 V, 1 Hz, and 2 ms (24 h on, 24 h off, for one week). The expression levels of proteins were examined by Western blotting. The intervention of maca and EPS upregulated the expression of MHC-fast/slow (both
MeSH term(s)	Humans ; Stress, Mechanical ; Muscles ; Muscle Contraction ; Nutritional Status ; Hypertrophy
Language	English
Publishing date	2023-09-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15184083
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Treatment of sick sinus syndrome in a patient with cardiac lymphoma via chemotherapy without pacemaker implantation: A case report.

Hirakawa, Yuri / Tsuda, Shigeyasu / Sugimoto, Takeshi

Clinical case reports

2022 Volume 10, Issue 4, Page(s) e05649

Abstract: Successful treatment of the acute phase of bradycardia in patients with cardiac lymphoma via medical therapy alone has not been reported. This case report describes the successful treatment of sick sinus syndrome in an 84-year-old man with cardiac ... ...

Abstract	Successful treatment of the acute phase of bradycardia in patients with cardiac lymphoma via medical therapy alone has not been reported. This case report describes the successful treatment of sick sinus syndrome in an 84-year-old man with cardiac lymphoma via chemotherapy without pacemaker implantation.
Language	English
Publishing date	2022-04-04
Publishing country	England
Document type	Case Reports
ZDB-ID	2740234-4
ISSN	2050-0904
ISSN	2050-0904
DOI	10.1002/ccr3.5649
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Article ; Online: The age-related required number of zygotes estimated from prior clinical studies of preimplantation genetic testing for aneuploidy (PGT-A).

Mariya, Tasuku / Sugimoto, Takeshi / Kato, Takema / Endo, Toshiaki / Kurahashi, Hiroki

Systems biology in reproductive medicine

2023 Volume 69, Issue 1, Page(s) 50–56

Abstract: Women who are undergoing preimplantation genetic testing for aneuploidy (PGT-A) often wish to know how many eggs will be required to optimize the chances of a live birth. However, no precise data on this can yet be provided during genetic counseling for ... ...

Abstract	Women who are undergoing preimplantation genetic testing for aneuploidy (PGT-A) often wish to know how many eggs will be required to optimize the chances of a live birth. However, no precise data on this can yet be provided during genetic counseling for this procedure. On the basis of PGT-A data from related studies and current databases, we have estimated that the number of zygotes required for a 50% chance of a live birth is 8 at age 40 but increases markedly to 21 at age 43. PGT-A markedly reduces the miscarriage rate per embryo transfer but does not alleviate the extremely high number of zygotes required for a live birth in women of an advanced maternal age. Detailed genetic counseling will therefore be desirable prior to undergoing this procedure.
MeSH term(s)	Pregnancy ; Female ; Humans ; Adult ; Preimplantation Diagnosis/methods ; Zygote ; Genetic Testing/methods ; Abortion, Spontaneous/genetics ; Aneuploidy ; Retrospective Studies ; Blastocyst ; Fertilization in Vitro/methods
Language	English
Publishing date	2023-01-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2417234-0
ISSN	1939-6376 ; 1939-6368
ISSN (online)	1939-6376
ISSN	1939-6368
DOI	10.1080/19396368.2022.2151387
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Recurrent Fever due to

Takenaka, Kei / Sugimoto, Takeshi / Kawamura, Kohei / Fukumoto, Takeshi / Onuma, Kenichiro / Naito, Takuya / Oka, Masahiro

Case reports in oncology

2021 Volume 14, Issue 3, Page(s) 1315–1322

Abstract: Fever due ... ...

Abstract	Fever due to
Language	English
Publishing date	2021-09-16
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2458961-5
ISSN	1662-6575
ISSN	1662-6575
DOI	10.1159/000518685
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Article ; Online: The lactate response to a second bout of exercise is not reduced in a concurrent lower-limb exercise program

Hayato Tsukamoto / Tadashi Suga / Kento Dora / Takeshi Sugimoto / Keigo Tomoo / Tadao Isaka / Takeshi Hashimoto

Scientific Reports, Vol 13, Iss 1, Pp 1-

2023 Volume 9

Abstract: Abstract We aimed to evaluate the blood lactate level in response to two bouts of exercise. First, we hypothesized that blood lactate elevation in response to moderate-intensity aerobic exercise (MIAE) would be lower at the end of the second bout of MIAE ...

Abstract	Abstract We aimed to evaluate the blood lactate level in response to two bouts of exercise. First, we hypothesized that blood lactate elevation in response to moderate-intensity aerobic exercise (MIAE) would be lower at the end of the second bout of MIAE than the first bout of MIAE. In this context, we also hypothesized that lactate accumulation at the end of resistance exercise (RE) would be reduced if MIAE is performed before RE (i.e., concurrent exercise; CE). If so, we hypothesized that the order of the CE (i.e., RE + MIAE vs. MIAE + RE) influences blood lactate kinetics. To test the hypotheses, forty-three healthy men participated in three studies. In study 1, 20 men (age 21 ± 2 years) performed two bouts of a 20-min MIAE separated by a 20-min rest interval. In study 2, 11 men (age 22 ± 1 years) performed RE only and CE (MIAE + RE; ARCE) with a 20-min rest interval in a crossover design. In study 3, 12 men (age 21 ± 2 years) performed both CEs, which were ARCE and RE + MIAE (RACE), with a 20-min rest interval in a crossover design. We measured blood lactate before and at the end of each exercise session. In study 1, the blood lactate response to the second bout of MIAE was lower than that of the first bout (P < 0.001, r = 0.68). However, the blood lactate response to the ARCE trial was not lower than the response to the RE trial in study 2 (P = 0.475, r = 0.22). The results of study 3 showed that the RACE and ARCE trials induced a similar lactate response (MIAE P = 0.423, r = 0.28; RE P = 0.766, d = 0.03). These observations indicate that whereas lactate accumulation might be diminished by a second bout of MIAE, a different type of exercise (i.e., aerobic/resistance) did not result in a diminished lactate accumulation in response to a second bout of exercise.
Keywords	Medicine ; R ; Science ; Q
Subject code	796
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Relationship between Urinary Metabolomic Profiles and Depressive Episode in Antarctica.

Kasuya, Kazuhiko / Imura, Satoshi / Ishikawa, Takashi / Sugimoto, Masahiro / Inoue, Takeshi

International journal of molecular sciences

2023 Volume 24, Issue 2

Abstract: Antarctic expeditions have a high risk of participant depression owing to long stays and isolated environments. By quantifying the stress state and changes in biomolecules over time before the onset of depressive symptoms, predictive markers of ... ...

Abstract	Antarctic expeditions have a high risk of participant depression owing to long stays and isolated environments. By quantifying the stress state and changes in biomolecules over time before the onset of depressive symptoms, predictive markers of depression can be explored. Here, we evaluated the psychological changes in 30 participants in the Japanese Antarctic Research Expedition using the Patient Health Questionnaire-9 (PHQ-9). Urinary samples were collected every three months for a year, and comprehensive urinary metabolomic profiles were quantified using liquid chromatography time-of-flight mass spectrometry. Five participants showed major depressive episodes (PHQ-9 ≥ 10) at 12 months. The urinary metabolites between these participants and the 25 unaffected participants were compared at individual metabolite and pathway levels. The individual comparisons showed the most significant differences at 12 months in 14 metabolites, including ornithine and beta-alanine. Data from shorter stays showed less significant differences. In contrast, pathway and enrichment analyses showed the most significant difference at three months and a less significant difference at longer stays. These time transitions of urinary metabolites could help in the development of urinary biomarkers to detect subjects with depressive episodes at an early stage.
MeSH term(s)	Humans ; Antarctic Regions ; Depressive Disorder, Major ; Metabolomics/methods ; Mass Spectrometry/methods ; Chromatography, Liquid/methods
Language	English
Publishing date	2023-01-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24020943
Database	MEDical Literature Analysis and Retrieval System OnLINE

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