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Article ; Online: Pulmonary Artery Diameter Measurement and Semiquantitative Visual Scoring with Q-SPECT-CT in Acute Pulmonary Embolism.

Silov, Guler / Ayan, Asli

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

2023 Volume 33, Issue 11, Page(s) 1229–1234

Abstract: Objective: To investigate whether pulmonary artery diameters obtained from lung perfusion single-photon emission computed tomography-computed tomography (SPECT-CT) images and semiquantitative visual scoring (SVS) could serve as predictors of chronic ... ...

Abstract	Objective: To investigate whether pulmonary artery diameters obtained from lung perfusion single-photon emission computed tomography-computed tomography (SPECT-CT) images and semiquantitative visual scoring (SVS) could serve as predictors of chronic pulmonary thromboembolic disease (CPTED) in acute pulmonary embolism patients (APE). Study design: Observational study. Place and Duration of the Study: Department of Nuclear Medicine, Samsun Provincial Health Directorate, Gazi State Hospital, Samsun, Turkey, from January 2016 to March 2021. Methodology: A total of 142 patients undergoing lung perfusion SPECT-CT were included in this study. Patients were classified as APE (+) (n=42) and APE (-) (n=100) based on laboratory and radiological findings, clinical diagnosis, and treatment protocol. Non-contrast CT images were used to determine the diameters (mm) of the main (MPA), right (RPA), and left (LPA) pulmonary arteries and the main pulmonary artery/aorta (PA/AO) ratio. All perfusion defects were scored using SVS for the PE (+) group. Seventeen patients with a diagnosis of CPTED were followed up. The scores and arterial diameters of recovered APE and follow-up patients were compared. Results: The mean diameters (mm) of MPA, RPA, and LPA and PA/AO ratio were 29.74±5.51, 21.73±4.11, 22.74±4.16, and 0.83±0.16 in the APE (+) group and 26.18±4.99, 19.35±3.84, 19.49±4.15, and 0.77±0.15 in the APE (-) group, respectively (p<0.001). Mean MPA diameter (mm), total defect (TD), right visual defect (RVD), and PA/AO ratio were 31.67±15.65, 29.88±15.59, 17.65±10.51, and 0.91±0.18 in the CPTED group and 28.06±4.59, 18.92±13.30, 10.4±7.41, and 0.78±0.15 in the recovered APE group, respectively (p<0.05). Conclusion: Assessment of pulmonary artery diameter and PA/AO ratio may indicate APE, but TD and RVD scores may be predictive factors for CPTED when included in the assessment along with MPA dilatation and PA/AO ratio. Key words: Acute pulmonary embolism, Pulmonary artery diameter, Lung SPECT-CT, Chronic pulmonary thromboembolic disease, Semi-quantitative visual scoring.
MeSH term(s)	Humans ; Animals ; Pulmonary Artery/diagnostic imaging ; Pulmonary Embolism/diagnostic imaging ; Acute Disease ; Lung Diseases ; Tomography, X-Ray Computed/methods ; Tomography, Emission-Computed, Single-Photon/methods ; Hominidae ; Retrospective Studies
Language	English
Publishing date	2023-11-06
Publishing country	Pakistan
Document type	Observational Study ; Journal Article
ZDB-ID	2276646-7
ISSN	1681-7168 ; 1022-386X
ISSN (online)	1681-7168
ISSN	1022-386X
DOI	10.29271/jcpsp.2023.11.1229
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Article ; Online: An unusual metastasis of prostate cancer detected with

Asli Ayan, H / Zor, M / Yildiz, B / Bedir, S

Revista espanola de medicina nuclear e imagen molecular

2019 Volume 38, Issue 4, Page(s) 256–257

Title translation	Metástasis inusual del cáncer de próstata en el cuerpo esponjoso del pene detectada mediante PET/TC con
MeSH term(s)	Aged ; Humans ; Male ; Membrane Glycoproteins ; Organometallic Compounds ; Penile Neoplasms/diagnostic imaging ; Penile Neoplasms/secondary ; Positron Emission Tomography Computed Tomography/methods ; Prostatic Neoplasms/pathology ; Radiopharmaceuticals
Chemical Substances	Membrane Glycoproteins ; Organometallic Compounds ; Radiopharmaceuticals ; gallium 68 PSMA-11
Language	Spanish
Publishing date	2019-01-17
Publishing country	Spain
Document type	Case Reports ; Journal Article
ISSN	2253-8089
ISSN (online)	2253-8089
DOI	10.1016/j.remn.2018.09.008
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Article: Guide for Nuclear Medicine Applications During the COVID-19 Outbreak

Ayan, Asli / Kiraç, F Suna

Mol Imaging Radionucl Ther

Abstract: A viral pneumonia rapidly spread from Wuhan, China to all countries in late 2019. In February 2020, WHO named as Coronavirus Disease 2019 (COVID-19) and declared the pandemic on March 11, 2020. To prevent the spread of COVID-19, Ministry of Health of ... ...

Abstract	A viral pneumonia rapidly spread from Wuhan, China to all countries in late 2019. In February 2020, WHO named as Coronavirus Disease 2019 (COVID-19) and declared the pandemic on March 11, 2020. To prevent the spread of COVID-19, Ministry of Health of Republic of Turkey and international institutions have published documents defining hygiene rules. After the lung computerized tomography (CT) findings which are important in the diagnosis of COVID-19 are described, protection measures against infection were defined in radiology departments. There is no publication involving protection measures for diagnostic and therapeutic procedures in nuclear medicine (NM) (appointment, patient acceptance, imaging and treatment procedures, disinfection etc). There are two reports on CT findings suggesting COVID-19 in 18F-fluorodeoxyglucose positron emission tomography/CT scan. These lung findings detected in hybrid images will be helpful in the early diagnosis of pulmonary involvement. Infected cases may be asymptomatic and can unintentionally disseminate the virus to surrounding people. This advisory guide has been prepared to avoid infection risk in NM clinics. During the COVID-19 outbreak, staff must use proper personal protective equipment and patients should be evaluated as the elective case according to clinical status. A questionnaire should be made for COVID-19. In cancer cases requiring urgent treatment, radionuclide treatment (RNT) should be planned according to the COVID-19 test result. If the result is negative, RNT can be applied; but if not or if the symptoms are present, RNT must be postponed. Following imaging procedures, scanners and room surfaces should be cleaned by personnel with proper disinfection training.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32368875
Database	COVID19

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Article ; Online: Bilateral Tibial Stress Injuries in Recreational Athletes of Army

Aslı Ayan / Aydan Örsçelik

Spor Hekimligi Dergisi, Vol 55, Iss 1, Pp 14-

2020 Volume 20

Abstract: Objective: Lower extremity stress injuries cause moderate to severe functional restrictions that frequently preclude attendance in sports, recreational and occupational activities involving vigorous, repetitive lower limb training. The purpose of this ... ...

Abstract	Objective: Lower extremity stress injuries cause moderate to severe functional restrictions that frequently preclude attendance in sports, recreational and occupational activities involving vigorous, repetitive lower limb training. The purpose of this study is to evaluate the relation between diagnosis and symptom duration and exercise periods in cases with bilateral stress injuries diagnosed by physical examination and radionuclide imaging. Materials and Methods: Twenty-five patients pre-diagnosed with bilateral stress injuries, aged between 19 and 35 years (3 female, 22 male) were enrolled in this study. Patient anamnesis, demographic information, the time span of painful period, duration of exercise per week, bones scans and SPECT/CT findings were evaluated. Stress injury groups were identified as bilateral shin splints (SS), bilateral stress fractures (SF), shin splint and stress fractures (SS+SF) according to their uptake properties on three phase bone scan (TPBS) and SPECT/CT images and physical examination findings. Results: There were no statistically significant differences between the groups according to age, and duration of symptoms (χ2 = 3,327, p=0,344). Conclusion: Bilateral stress injury is a rare condition in military personnel and athletes. Duration of exercise seems to be the major risk factor for the stress injury development.
Keywords	stress fractures ; medial tibial stress syndrome ; recreational athlete ; Sports ; GV557-1198.995 ; Sports medicine ; RC1200-1245
Subject code	796
Language	English
Publishing date	2020-03-01T00:00:00Z
Publisher	Turkish Sports Medicine Association
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Guide for Nuclear Medicine Applications During the COVID-19 Outbreak

Aslı Ayan / F. Suna Kıraç

Molecular Imaging and Radionuclide Therapy, Vol 29, Iss 2, Pp 49-

2020 Volume 58

Abstract	A viral pneumonia rapidly spread from Wuhan, China to all countries in late 2019. In February 2020, WHO named as Coronavirus Disease 2019 (COVID-19) and declared the pandemic on March 11, 2020. To prevent the spread of COVID-19, Ministry of Health of Republic of Turkey and international institutions have published documents defining hygiene rules. After the lung computerized tomography (CT) findings which are important in the diagnosis of COVID-19 are described, protection measures against infection were defined in radiology departments. There is no publication involving protection measures for diagnostic and therapeutic procedures in nuclear medicine (NM) (appointment, patient acceptance, imaging and treatment procedures, disinfection etc). There are two reports on CT findings suggesting COVID-19 in 18F--fluorodeoxyglucose positron emission tomography/CT scan. These lung findings detected in hybrid images will be helpful in the early diagnosis of pulmonary involvement. Infected cases may be asymptomatic and can unintentionally disseminate the virus to surrounding people. This advisory guide has been prepared to avoid infection risk in NM clinics. During the COVID-19 outbreak, staff must use proper personal protective equipment and patients should be evaluated as the elective case according to clinical status. A questionnaire should be made for COVID-19. In cancer cases requiring urgent treatment, radionuclide treatment (RNT) should be planned according to the COVID-19 test result. If the result is negative, RNT can be applied; but if not or if the symptoms are present, RNT must be postponed. Following imaging procedures, scanners and room surfaces should be cleaned by personnel with proper disinfection training.
Keywords	coronavirus ; covid-19 outbreak ; nuclear medicine staff ; positron emission tomography/computerized tomography ; infection protection rules ; disinfection ; Medicine ; R ; Medicine (General) ; R5-920 ; Medical physics. Medical radiology. Nuclear medicine ; R895-920 ; covid19
Subject code	610
Language	English
Publishing date	2020-06-01T00:00:00Z
Publisher	Galenos Yayinevi
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Primary Diffuse Leptomeningeal Melanomatosis of Spine: 18F-FDG PET Findings.

Ayan, Asli / Akbulut, Aylin / Deveci, Guzin / Koca, Gokhan

Clinical nuclear medicine

2018 Volume 44, Issue 2, Page(s) 137–139

Abstract: Primary diffuse leptomeningeal melanomatosis is a rare variant of malignant melanoma of the central nervous system, arising from melanocytes of leptomeninges. It may involve leptomeninges and may invade brain superficially. The diagnosis of the disease ... ...

Abstract	Primary diffuse leptomeningeal melanomatosis is a rare variant of malignant melanoma of the central nervous system, arising from melanocytes of leptomeninges. It may involve leptomeninges and may invade brain superficially. The diagnosis of the disease with conventional imaging techniques is quite difficult. This case demonstrates the F-FDG uptake of primary diffuse leptomeningeal melanomatosis matching with MRI contrast enhancement regions particularly in the lower thoracic and superior lumbar region.
MeSH term(s)	Adult ; Fluorodeoxyglucose F18 ; Humans ; Male ; Melanoma/diagnostic imaging ; Melanoma/pathology ; Meningeal Neoplasms/diagnostic imaging ; Meningeal Neoplasms/pathology ; Positron Emission Tomography Computed Tomography ; Spine/diagnostic imaging ; Spine/pathology
Chemical Substances	Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2018-12-05
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	197628-x
ISSN	1536-0229 ; 0363-9762
ISSN (online)	1536-0229
ISSN	0363-9762
DOI	10.1097/RLU.0000000000002384
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Article: Guide for Nuclear Medicine Applications During the COVID-19 Outbreak.

Ayan, Aslı / Kıraç, F Suna

Molecular imaging and radionuclide therapy

2019 Volume 29, Issue 2, Page(s) 49–58

Abstract	A viral pneumonia rapidly spread from Wuhan, China to all countries in late 2019. In February 2020, WHO named as Coronavirus Disease 2019 (COVID-19) and declared the pandemic on March 11, 2020. To prevent the spread of COVID-19, Ministry of Health of Republic of Turkey and international institutions have published documents defining hygiene rules. After the lung computerized tomography (CT) findings which are important in the diagnosis of COVID-19 are described, protection measures against infection were defined in radiology departments. There is no publication involving protection measures for diagnostic and therapeutic procedures in nuclear medicine (NM) (appointment, patient acceptance, imaging and treatment procedures, disinfection etc). There are two reports on CT findings suggesting COVID-19 in
Keywords	covid19
Language	English
Publishing date	2019-05-09
Publishing country	Turkey
Document type	Journal Article
ISSN	2146-1414
ISSN	2146-1414
DOI	10.4274/mirt.galenos.2020.33600
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Article ; Online: Pyrolysis of grape bagasse: effect of pyrolysis conditions on the product yields and characterization of the liquid product.

Demiral, Ilknur / Ayan, Emine Asli

Bioresource technology

2011 Volume 102, Issue 4, Page(s) 3946–3951

Abstract: In this study, pyrolysis of grape bagasse was investigated with the aim to study the product distribution and their chemical compositions and to identify optimum process conditions for maximizing the bio-oil yield. Particular investigated process ... ...

Abstract	In this study, pyrolysis of grape bagasse was investigated with the aim to study the product distribution and their chemical compositions and to identify optimum process conditions for maximizing the bio-oil yield. Particular investigated process variables were temperature (350-600°C), heating rate (10-50°C/min) and nitrogen gas flow rate (50-200 cm(3)/min). The maximum oil yield of 27.60% was obtained at the final pyrolysis temperature of 550°C, sweeping gas flow rate of 100 cm(3)/min and heating rate of 50°C/min in a fixed-bed reactor. The elemental analysis and heating value of the bio-oils were determined, and then the chemical composition of the bio-oil was investigated using chromatographic and spectroscopic techniques such as column chromatography, (1)H NMR and FTIR. The fuel properties of the bio-oil such as flash point, viscosity and density were also determined. The bio-oils obtained from grape bagasse were presented as an environmentally friendly feedstock candidate for bio-fuels.
MeSH term(s)	Biotechnology/methods ; Carbon/chemistry ; Cellulose/chemistry ; Chromatography/methods ; Hot Temperature ; Magnetic Resonance Spectroscopy/methods ; Oils/chemistry ; Spectrophotometry/methods ; Spectroscopy, Fourier Transform Infrared/methods ; Temperature ; Vitis/chemistry
Chemical Substances	Oils ; Carbon (7440-44-0) ; Cellulose (9004-34-6) ; bagasse (9006-97-7)
Language	English
Publishing date	2011-02
Publishing country	England
Document type	Journal Article
ZDB-ID	1065195-0
ISSN	1873-2976 ; 0960-8524
ISSN (online)	1873-2976
ISSN	0960-8524
DOI	10.1016/j.biortech.2010.11.077
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Article: Impact of tall cell variant histology on predicting relapse and changing the management of papillary thyroid carcinoma patients.

Gunalp, Bengul / Okuyucu, Kursat / Ince, Semra / Ayan, Aslı / Alagoz, Engin

Hellenic journal of nuclear medicine

2017 Volume 20, Issue 2, Page(s) 122–127

Abstract: Objective: There has been much discussion recently about the risk category of tall cell variant (TVC) histology and its effects on the management of papillary thyroid carcinoma (PTC). We, therefore, undertook a retrospective study to compare stage- ... ...

Abstract	Objective: There has been much discussion recently about the risk category of tall cell variant (TVC) histology and its effects on the management of papillary thyroid carcinoma (PTC). We, therefore, undertook a retrospective study to compare stage-matched risk factors and recurrence rates between classical PTC (cPTC) patients and patients with TCV histology. Subjects and methods: A total of 3128 well-differentiated thyroid carcinoma patients who were treated and followed-up for more than 5 years in our clinic from 1995 to 2016 were included in this study. There were 2783 PTC (89%) patients, 1113 (40%) of them were cPTC and 56 (2%) of them were TCV patients. Results: In all stages, the stage-matched incidence of extrathyroidal extension (ETE), lymphovascular invasion and initial lymph node metastases were significantly higher in TCV patients than in cPTC patients (P<0.001). Recurrence was in 10 of 27 patients (37%) with TCV and in 91 of 890 (10%) patients with cPTC diagnosed in stage I (odds ratio (OR)=5.16); in 4 of 6 patients with TCV and 18 of 84 (21%) patients with cPTC in stage II (OR=7.33); in 5 of 6 patients with TCV and 11 of 46 (23%) patients with cPTC in stage III (OR=15.90); and in 13 of 17 patients with TCV and 31 of 93 (33%) patients with cPTC in stage IV (OR=6.50). Stage-matched recurrence rates were found significantly higher in all stages of TCV patients than in cPTC patients (OR=8.49, P<0.001). Recurrence with distant metastases was seen more frequently in TCV patients than in cPTC patients (P<0.001) and treatment of metastatic disease was more difficult in TCV patients. Conclusion: Tall cell variant was an independent poor prognostic factor in papillary thyroid carcinoma patients even if they were diagnosed at early stages of the disease. Patients with tall cell variant histology required more aggressive therapeutic approach and closer follow-up than classical patients.
MeSH term(s)	Aged ; Carcinoma/epidemiology ; Carcinoma/pathology ; Carcinoma, Papillary ; Female ; Follow-Up Studies ; Humans ; Incidence ; Longitudinal Studies ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging ; Prevalence ; Prognosis ; Reproducibility of Results ; Retrospective Studies ; Risk Factors ; Sensitivity and Specificity ; Sex Distribution ; Thyroid Cancer, Papillary ; Thyroid Neoplasms/epidemiology ; Thyroid Neoplasms/pathology ; Tumor Burden ; Turkey/epidemiology
Language	English
Publishing date	2017-07-12
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2186026-9
ISSN	1790-5427 ; 1108-1430
ISSN	1790-5427 ; 1108-1430
DOI	10.1967/s002449910552
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Zs.A 6058: Show issues

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Article ; Online: Thyroid hemiagenesis and Graves' disease in a child.

Serdengeçti, Mustafa / Ayan, Asli / Sari, Oktay

Clinical nuclear medicine

2009 Volume 34, Issue 12, Page(s) 884–885

Abstract: Hemiagenesis of the thyroid is a rare malformation and Graves' disease with ophthalmopathy is reported quite rarely in adult patients but is not seen in children. This is a report of an 8-year-old girl with congenital absence of the left thyroid lobe, or ...

Abstract	Hemiagenesis of the thyroid is a rare malformation and Graves' disease with ophthalmopathy is reported quite rarely in adult patients but is not seen in children. This is a report of an 8-year-old girl with congenital absence of the left thyroid lobe, or hemiagenesis.
MeSH term(s)	Child ; Female ; Graves Disease/complications ; Graves Disease/diagnostic imaging ; Humans ; Radionuclide Imaging ; Thyroid Dysgenesis/complications ; Thyroid Dysgenesis/diagnostic imaging ; Ultrasonography
Language	English
Publishing date	2009-12
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	197628-x
ISSN	1536-0229 ; 0363-9762
ISSN (online)	1536-0229
ISSN	0363-9762
DOI	10.1097/RLU.0b013e3181bed120
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