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Article ; Online: Reply to Yubo Yang, Xin Wei, and Ping Han's Letter to the Editor re: Roger Li, Philippe E. Spiess, Scott M. Gilbert, Andrea Necchi. Towards Personalized Neoadjuvant Therapy for Muscle-invasive Bladder Cancer. Eur Urol 2019;76:4-6.

Li, Roger / Spiess, Philippe E / Gilbert, Scott M / Necchi, Andrea

2019 Volume 76, Issue 2, Page(s) e34

MeSH term(s)	Humans ; Neoadjuvant Therapy ; Urinary Bladder Neoplasms
Language	English
Publishing date	2019-05-02
Publishing country	Switzerland
Document type	Letter ; Comment
ZDB-ID	193790-x
ISSN	1873-7560 ; 1421-993X ; 0302-2838
ISSN (online)	1873-7560 ; 1421-993X
ISSN	0302-2838
DOI	10.1016/j.eururo.2019.04.030
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Article ; Online: Frederic E. Mohs, M.D. (1910-2002): physician and innovator.

Ross, Nicholas A / Saedi, Nazanin / Yeo, Charles J / Cowan, Scott

The American surgeon

2015 Volume 81, Issue 5, Page(s) 433–437

MeSH term(s)	General Surgery/history ; History, 20th Century ; History, 21st Century ; Inventions/history ; Physicians/history ; Wisconsin
Language	English
Publishing date	2015-05-12
Publishing country	United States
Document type	Biography ; Historical Article ; Journal Article ; Portrait
ZDB-ID	202465-2
ISSN	1555-9823 ; 0003-1348
ISSN (online)	1555-9823
ISSN	0003-1348
DOI	10.1177/000313481508100520
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Article ; Online: A Rapid Assessment Procedure to Develop A Non-Communicable Disease Prevention Pilot Health Communications Project Using E- and M-Health Communications in Pohnpei State, Federated States of Micronesia.

Sy, Angela / Marriott, Jahron / Tannis, Candace / Demment, Margaret / McIntosh, Scott / Hadley, Johnny / Albert, Pertina / Buenconsejo-Lum, Lee / Dye, Timothy

Hawai'i journal of health & social welfare

2020 Volume 79, Issue 6 Suppl 2, Page(s) 58–63

Abstract: ... heart disease, and cancer are a concern. Over 73% of Pohnpei's population is overweight or obese. E- and m ... identified through snowball sampling for interviews and group discussions about e-health readiness and NCD ...

Abstract	Pohnpei State of the Federated States of Micronesia, located in the Northwestern Pacific Ocean, has limited health research infrastructure; chronic non-communicable diseases (NCD) such as diabetes, heart disease, and cancer are a concern. Over 73% of Pohnpei's population is overweight or obese. E- and m- (mobile) health interventions are becoming more popular in low and middle income countries. A Rapid Assessment Procedure was conducted for formative research to identify the enabling factors and challenges related to health communication and technology in Pohnpei to address NCD prevention. Thirty-seven local stakeholders were identified through snowball sampling for interviews and group discussions about e-health readiness and NCD priorities, held in local settings. Interviews were audio recorded, with field notes taken. Data were iteratively coded using DEDOOSE. Diabetes emerged as the most serious NCD issue because both the health system and local community are having to deal with the complications and consequences. Stakeholders recommended that prevention should be integrated with diabetes treatment. Local health workers' teaching evidence-based diabetes prevention and other health promotion education were through handheld (mobile devices) was identified. The ability to readily access evidence-based health education materials and modules is compatible with community approaches providing tailored, individual and small group education and social support. This approach may serve as a key component of local NCD prevention communications initiatives integral to prevent diabetes and its complications as remote Small Island Nations face burgeoning NCD epidemics and dramatic shifts in diet and activity.
MeSH term(s)	Food Quality ; Health Promotion/methods ; Health Services Needs and Demand/statistics & numerical data ; Humans ; Micronesia/epidemiology ; Noncommunicable Diseases/epidemiology ; Noncommunicable Diseases/prevention & control ; Program Development/methods ; Risk Factors ; Telemedicine/instrumentation ; Telemedicine/methods ; Telemedicine/trends
Language	English
Publishing date	2020-06-25
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Review
ZDB-ID	2983566-5
ISSN	2641-5224 ; 2641-5216
ISSN (online)	2641-5224
ISSN	2641-5216
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Article: E.M. van Zinderen Bakker (1907–2002) and the study of African Quaternary palaeoenvironments

Neumann, Frank H / Louis Scott

Quaternary international. 2018 Nov. 30, v. 495

2018

Abstract: The scientific contributions of E.M. van Zinderen Bakker (1907–2002) included the introduction ...

Abstract	The scientific contributions of E.M. van Zinderen Bakker (1907–2002) included the introduction of pollen analysis to Quaternary studies in South Africa. His palaeoecological theories evolved while performing palynological research in Southern Africa (the Maluti Mountains, Florisbad, Aliwal North, the Namib Desert), East Africa (Kalambo Falls, Mount Kenya, Cherangani Hills) and on the subantarctic islands (Marion and Prince Edward Islands). He was involved in the first radiocarbon dating from South Africa at Florisbad. Due to quantitative palynological studies he abandoned Wayland's (1929) Pluvial Theory that was generally accepted in the 1960s. He correlated observations of climate changes in Africa to data from marine borehole-cores and climatic fluctuations in the Northern Hemisphere. His observations led to the proposal that global temperature fluctuations are the primary cause of palaeoenvironmental changes. His studies culminated in a conceptual paleoecological model for the Last Glacial Maximum (LGM). Initially he based the model on symmetrical contraction of climatic belts about the equator that shifted the mid-latitude westerly wind system northward to increase the area receiving winter rainfall but later adjusted this by proposing a mechanism of westerly wind system intensification. He suggested that at this time grasslands had spread over wider areas in Southern Africa and that the tropical rain forests in the equatorial region fragmented. For interglacial periods he suggested that a southward shift of the Intertropical Convergence Zone (ITCZ) resulted in widespread humidity in the Congo Basin while large areas of the interior of Southern Africa became arid. Some of his ideas, especially his conceptual models of Quaternary vegetation and climate, are still relevant to the explanation of recent discoveries.
Keywords	basins ; climate ; climate change ; grasslands ; humidity ; islands ; latitude ; models ; mountains ; paleoecology ; palynology ; pollen analysis ; radiocarbon dating ; rain ; temperature ; tropical rain forests ; wind direction ; winter ; Kenya ; South Africa
Language	English
Dates of publication	2018-1130
Size	p. 153-168.
Publishing place	Elsevier Ltd
Document type	Article
ISSN	1040-6182
DOI	10.1016/j.quaint.2018.04.017
Database	NAL-Catalogue (AGRICOLA)

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Article: Experimental and theoretical comparison of actinide and lanthanide bonding in M[N(EPR(2))(2)](3) complexes (M = U, Pu, La, Ce; E = S, Se, Te; R = Ph, iPr, H).

Gaunt, Andrew J / Reilly, Sean D / Enriquez, Alejandro E / Scott, Brian L / Ibers, James A / Sekar, Perumal / Ingram, Kieran I M / Kaltsoyannis, Nikolas / Neu, Mary P

Inorganic chemistry

2008 Volume 47, Issue 1, Page(s) 29–41

Abstract: Treatment of M[N(SiMe3)2]3 (M = U, Pu (An); La, Ce (Ln)) with NH(EPPh2)2 and NH(EPiPr2)2 (E = S, Se ... that the enhanced covalency in the M-E bond as group 16 is descended arises mostly from increased metal d-orbital ... afforded the neutral complexes M[N(EPR2)2]3 (R = Ph, iPr). Tellurium donor complexes were synthesized ...

Abstract	Treatment of M[N(SiMe3)2]3 (M = U, Pu (An); La, Ce (Ln)) with NH(EPPh2)2 and NH(EPiPr2)2 (E = S, Se), afforded the neutral complexes M[N(EPR2)2]3 (R = Ph, iPr). Tellurium donor complexes were synthesized by treatment of MI3(sol)4 (M = U, Pu; sol = py and M = La, Ce; sol = thf) with Na(tmeda)[N(TePiPr2)2]. The complexes have been structurally and spectroscopically characterized with concomitant computational modeling through density functional theory (DFT) calculations. The An-E bond lengths are shorter than the Ln-E bond lengths for metal ions of similar ionic radii, consistent with an increase in covalent interactions in the actinide bonding relative to the lanthanide bonding. In addition, the magnitude of the differences in the bonding is slightly greater with increasing softness of the chalcogen donor atom. The DFT calculations for the model systems correlate well with experimentally determined metrical parameters. They indicate that the enhanced covalency in the M-E bond as group 16 is descended arises mostly from increased metal d-orbital participation. Conversely, an increase in f-orbital participation is responsible for the enhancement of covalency in An-E bonds compared to Ln-E bonds. The fundamental and practical importance of such studies of the role of the valence d and f orbitals in the bonding of the f elements is emphasized.
MeSH term(s)	Actinoid Series Elements/chemistry ; Binding Sites ; Computer Simulation ; Crystallography, X-Ray ; Lanthanoid Series Elements/chemistry ; Ligands ; Models, Chemical ; Models, Molecular ; Organometallic Compounds/chemical synthesis ; Organometallic Compounds/chemistry ; Quantum Theory
Chemical Substances	Actinoid Series Elements ; Lanthanoid Series Elements ; Ligands ; Organometallic Compounds
Language	English
Publishing date	2008-01-07
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1484438-2
ISSN	1520-510X ; 0020-1669
ISSN (online)	1520-510X
ISSN	0020-1669
DOI	10.1021/ic701618a
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Article ; Online: Molecular epidemiological analysis of Escherichia coli sequence type ST131 (O25:H4) and blaCTX-M-15 among extended-spectrum-β-lactamase-producing E. coli from the United States, 2000 to 2009.

Johnson, James R / Urban, Carl / Weissman, Scott J / Jorgensen, James H / Lewis, James S / Hansen, Glen / Edelstein, Paul H / Robicsek, Ari / Cleary, Timothy / Adachi, Javier / Paterson, David / Quinn, John / Hanson, Nancy D / Johnston, Brian D / Clabots, Connie / Kuskowski, Michael A

Antimicrobial agents and chemotherapy

2012 Volume 56, Issue 5, Page(s) 2364–2370

Abstract: ... and ST131 with fluoroquinolone resistance. Thus, E. coli ST131 and bla(CTX-M-15) are emergent, widely ... spectrum-β-lactamase (ESBL) gene bla(CTX-M-15), is an emerging globally disseminated pathogen that has ... producing E. coli isolates from 15 U.S. centers (collected in 2000 to 2009) underwent PCR-based phylotyping ...

Abstract	Escherichia coli sequence type ST131 (from phylogenetic group B2), often carrying the extended-spectrum-β-lactamase (ESBL) gene bla(CTX-M-15), is an emerging globally disseminated pathogen that has received comparatively little attention in the United States. Accordingly, a convenience sample of 351 ESBL-producing E. coli isolates from 15 U.S. centers (collected in 2000 to 2009) underwent PCR-based phylotyping and detection of ST131 and bla(CTX-M-15). A total of 200 isolates, comprising 4 groups of 50 isolates each that were (i) bla(CTX-M-15) negative non-ST131, (ii) bla(CTX-M-15) positive non-ST131, (iii) bla(CTX-M-15) negative ST131, or (iv) bla(CTX-M-15) positive ST131, also underwent virulence genotyping, antimicrobial susceptibility testing, and pulsed-field gel electrophoresis (PFGE). Overall, 201 (57%) isolates exhibited bla(CTX-M-15), whereas 165 (47%) were ST131. ST131 accounted for 56% of bla(CTX-M-15)-positive- versus 35% of bla(CTX-M-15)-negative isolates (P < 0.001). Whereas ST131 accounted for 94% of the 175 total group B2 isolates, non-ST131 isolates were phylogenetically distributed by bla(CTX-M-15) status, with groups A (bla(CTX-M-15)-positive isolates) and D (bla(CTX-M-15)-negative isolates) predominating. Both bla(CTX-M-15) and ST131 occurred at all participating centers, were recovered from children and adults, increased significantly in prevalence post-2003, and were associated with molecularly inferred virulence. Compared with non-ST131 isolates, ST131 isolates had higher virulence scores, distinctive virulence profiles, and more-homogeneous PFGE profiles. bla(CTX-M-15) was associated with extensive antimicrobial resistance and ST131 with fluoroquinolone resistance. Thus, E. coli ST131 and bla(CTX-M-15) are emergent, widely distributed, and predominant among ESBL-positive E. coli strains in the United States, among children and adults alike. Enhanced virulence and antimicrobial resistance have likely promoted the epidemiological success of these emerging public health threats.
MeSH term(s)	Adult ; Bacterial Typing Techniques ; Child ; Child, Preschool ; Drug Resistance, Bacterial/genetics ; Electrophoresis, Gel, Pulsed-Field ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Escherichia coli/isolation & purification ; Escherichia coli/pathogenicity ; Escherichia coli Infections/epidemiology ; Escherichia coli Infections/microbiology ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Humans ; Longitudinal Studies ; Microbial Sensitivity Tests ; Molecular Epidemiology ; Phylogeny ; Polymerase Chain Reaction ; Sequence Analysis, DNA ; United States/epidemiology ; Virulence ; beta-Lactamases/genetics ; beta-Lactamases/metabolism
Chemical Substances	Escherichia coli Proteins ; beta-Lactamases (EC 3.5.2.6)
Language	English
Publishing date	2012-02-21
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	217602-6
ISSN	1098-6596 ; 0066-4804
ISSN (online)	1098-6596
ISSN	0066-4804
DOI	10.1128/AAC.05824-11
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Article ; Online: Re: Effectiveness of antibiotics given to asymptomatic men for an increased prostate specific antigen. S. Baltaci, E. Suer, A. H. Haliloglu, M. I. Gokce, A. H. Elhan and Y. Beduk. J Urol 2009; 181: 128-132.

Eggener, Scott E / Raman, Jay D

The Journal of urology

2009 Volume 182, Issue 1, Page(s) 396–397

MeSH term(s)	Anti-Bacterial Agents/administration & dosage ; Humans ; Male ; Monitoring, Physiologic/methods ; Neoplasm Staging ; Prognosis ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms/blood ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms/pathology ; Risk Assessment ; Severity of Illness Index ; Treatment Outcome
Chemical Substances	Anti-Bacterial Agents ; Prostate-Specific Antigen (EC 3.4.21.77)
Language	English
Publishing date	2009-07
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	3176-8
ISSN	1527-3792 ; 0022-5347
ISSN (online)	1527-3792
ISSN	0022-5347
DOI	10.1016/j.juro.2009.02.143
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Article: Clinical and epidemiological relevance of quantitating hepatitis E virus-specific immunoglobulin M.

Seriwatana, Jitvimol / Shrestha, Mrigendra P / Scott, Robert M / Tsarev, Sergei A / Vaughn, David W / Myint, Khin Saw Aye / Innis, Bruce L

Clinical and diagnostic laboratory immunology

2001 Volume 9, Issue 5, Page(s) 1072–1078

Abstract: Diagnosis of acute hepatitis E by detection of hepatitis E virus (HEV)-specific immunoglobulin M ... as an optimum cut point. The median HEV IgM level in 36 patients with acute hepatitis E fell from 3,000 to 100 ... for distinguishing recent from remote IgM responses. Among three hepatitis E case series, determination of the HEV ...

Abstract	Diagnosis of acute hepatitis E by detection of hepatitis E virus (HEV)-specific immunoglobulin M (IgM) is an established procedure. We investigated whether quantitation of HEV IgM and its ratio to HEV total Ig furnished more information than conventional IgM tests that are interpreted as positive or negative. A previously described indirect immunoassay for total Ig against a baculovirus-expressed HEV capsid protein was modified to quantitate HEV-specific IgM in Walter Reed (WR) antibody units by using a reference antiserum and the four-parameter logistic model. A receiver-operating characteristics curve derived from 197 true-positive specimens and 449 true-negative specimens identified 30 WR units/ml as an optimum cut point. The median HEV IgM level in 36 patients with acute hepatitis E fell from 3,000 to 100 WR units/ml over 6 months, suggesting that 100 WR units/ml would be a more appropriate cut point for distinguishing recent from remote IgM responses. Among three hepatitis E case series, determination of the HEV IgM-to-total-Ig ratio in acute-phase serum revealed that most patients had high ratios consistent with primary infections whereas a few had low ratios, suggesting that they had sustained reinfections that elicited anamnestic antibody responses. The diagnostic utility of the new IgM test was similar to that of a commercially available test that uses different HEV antigens. In conclusion, we found that HEV IgM can be detected specifically in >95% of acute hepatitis E cases defined by detection of the virus genome in serum and that quantitation of HEV IgM and its ratio to total Ig provides insight into infection timing and prior immunity.
MeSH term(s)	DNA, Viral/analysis ; Hepatitis Antibodies/blood ; Hepatitis E/diagnosis ; Hepatitis E/epidemiology ; Hepatitis E/immunology ; Hepatitis E virus/genetics ; Hepatitis E virus/isolation & purification ; Humans ; Immunoenzyme Techniques/methods ; Immunoenzyme Techniques/standards ; Immunoglobulin G/blood ; Immunoglobulin M/blood ; Kinetics ; Recurrence ; Reference Standards ; Sensitivity and Specificity ; Seroepidemiologic Studies
Chemical Substances	DNA, Viral ; Hepatitis Antibodies ; Immunoglobulin G ; Immunoglobulin M
Language	English
Publishing date	2001-05-07
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1193675-7
ISSN	1098-6588 ; 1071-412X
ISSN (online)	1098-6588
ISSN	1071-412X
DOI	10.1128/cdli.9.5.1072-1078.2002
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Book: E. M. Forster

Gardner, Philip / Forster, Edward Morgan / Scott-Kilvert, Ian

(Writers and their work ; 261)

1977

Author's details	by Philip Gardner. Ed. by Ian Scott-Kilvert
Series title	Writers and their work ; 261
Language	English
Size	43 S.
Publisher	Longman Group
Publishing place	Harlow, Essex
Document type	Book
Note	Bibliogr. E. M. Forster und Literaturverz. S. 39 - 43
ISBN	0582012694 ; 9780582012691
Database	Former special subject collection: coastal and deep sea fishing

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Book: Neuroscience

Lamantia, Anthony-Samuel / Purves, Dale / Augustine, George J. / Groh, Jennifer M. / White, Leonard E. / Huettel, Scott A.

2023

Author's details	George Augustine is a neuroscientist known for his work on presynaptic mechanisms of neurotransmitter release and his contributions to the development of optogenetics, a too to control neural activity using light. He is a Professor o Neuroscience and Mental Health, and the Irene Tan Liang Kheng Chari Professor in Neuroscience at Nanyang Technological University in Singapore. Jennifer Groh studies how the brain processes spatial information, with a particular emphasis on vision, hearing, and eye movements. She is the author of an award-winning popular science book on these topics. She is a Professor of Neurobiology and of Psychology and Neuroscience at Duke University, where she also holds secondary appointments in Computer Science and Biomedical Engineering. Scott Huettel studies the neural mechanisms of decision making and has been recognized for his work in social neuroscience and neuroeconomics. He is a Professor of Psychology and Neuroscience at Duke University, where he also ho
Size	1008 p.
Publisher	Oxford University Press
Document type	Book
Note	PDA Manuell_25
Format	235 x 276 x 43
ISBN	9780197572511 ; 0197572510
Database	PDA

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