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  1. Article ; Online: Penile Pearls and Pearling: Characteristics and Social Identity from the Perspective of Forensic Pathologists.

    Leković, Aleksa / Živković, Vladimir / Nikolić, Slobodan

    Archives of sexual behavior

    2024  Volume 53, Issue 4, Page(s) 1395–1401

    Abstract: Penile pearls are artificial implants placed beneath the skin of a penis to provide enhanced sexual experience for the partner or present a stigma of a particular social subgroup (e.g., prisoner, member of a gang). This genital modification is usually ... ...

    Abstract Penile pearls are artificial implants placed beneath the skin of a penis to provide enhanced sexual experience for the partner or present a stigma of a particular social subgroup (e.g., prisoner, member of a gang). This genital modification is usually encountered in men of low socioeconomic status and prisoners who might (self) implant improvised pearls under poor sanitary conditions. We have only recently started to encounter penile pearls on autopsy, incidentally. The aim of this study was to analyze our autopsy cases with penile pearls to assess the characteristics of these subjects regarding their socioeconomic status, history of imprisonment, substance abuse, as well as the characteristics of implants. Nineteen men were included. Most were born in the 1970s and 1980s, with only elementary/vocational school education (n = 10). Only five men graduated from high school. At least 14 were in prison at some point in life and 13 were unemployed. Ten men were unmarried. In 11 men, regular alcohol consumption was reported. 12 used illicit substances, most with a history of heroin injection. Penile pearls were improvised and made of rigid plastic in 10 men, eight were of soft silicone-like material, and one was of metal. A distinct characteristic was a ribbed contour of some implants. Although this genital modification seems to gain more attention outside of described vulnerable groups, it mostly remains limited to them in our region. It is most likely performed in improvised, non-professional, unsanitary conditions, probably in prisons.
    MeSH term(s) Male ; Humans ; Social Identification ; Pathologists ; Penis ; Sexual Behavior ; Prisons ; Prisoners
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 184221-3
    ISSN 1573-2800 ; 0004-0002
    ISSN (online) 1573-2800
    ISSN 0004-0002
    DOI 10.1007/s10508-023-02791-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Subendocardial hemorrhages in a case of complete avulsion of the heart.

    Nikolić, Slobodan / Živković, Vladimir

    Forensic science, medicine, and pathology

    2022  Volume 18, Issue 2, Page(s) 214–218

    Abstract: We present a case of a 66-year-old man who died on the scene in a traffic accident. He was a car driver involved in a head-on collision with a bus. Autopsy performed 4 days after death showed multiple head, torso, and limb injuries, including complete ... ...

    Abstract We present a case of a 66-year-old man who died on the scene in a traffic accident. He was a car driver involved in a head-on collision with a bus. Autopsy performed 4 days after death showed multiple head, torso, and limb injuries, including complete avulsion of the heart from the great vessels and avulsion of both lungs from the tracheobronchial tree due to rapid deceleration. Gross examination of the heart was remarkable for patchy hemorrhages beneath the endocardium involving the left side of the interventricular septum and papillary muscles. Histological examination identified streaky subendocardial hemorrhages and perivascular hemorrhages in the subendocardial myocardium. Since the death, in this case, was instantaneous, the most likely mechanism of subendocardial hemorrhages involved a precipitous decrease in left ventricle pressure, as it is improbable that the timeline of events allowed for a catecholamine surge to occur and take effect. Findings in this case also suggest that subendocardial hemorrhages are an indicator of intravital trauma and that the time required for them to develop is very short.
    MeSH term(s) Accidents, Traffic ; Aged ; Autopsy ; Endocardium/pathology ; Heart Diseases ; Hemorrhage/etiology ; Hemorrhage/pathology ; Humans ; Male
    Language English
    Publishing date 2022-03-17
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2195904-3
    ISSN 1556-2891 ; 1547-769X
    ISSN (online) 1556-2891
    ISSN 1547-769X
    DOI 10.1007/s12024-022-00467-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Subendocardial hemorrhages in a case of crush asphyxia.

    Leković, Aleksa / Živković, Vladimir / Nikolić, Slobodan

    Journal of forensic and legal medicine

    2023  Volume 95, Page(s) 102506

    Abstract: This case represents a 27-year-old man, who was found dead in a truckload, trapped between several coils of steel wire, each weighing 500 kg. The autopsy was remarkable for subendocardial hemorrhages in addition to Perthes' syndrome and florid internal ... ...

    Abstract This case represents a 27-year-old man, who was found dead in a truckload, trapped between several coils of steel wire, each weighing 500 kg. The autopsy was remarkable for subendocardial hemorrhages in addition to Perthes' syndrome and florid internal findings: congestion/cyanosis of the cervical organs, intrathyroidal and submucosal bleedings. All this implies that compression significantly raised intrathoracic pressure. This might have reached a point that obstructed venous blood return and restricted filling of the right heart during diastole, while simultaneously preserving the function of a left ventricle for some time. A precipitous fall of the blood pressure and consequent decrease in the left ventricle filling, with a pressure gradient between the ventricular lumen and higher-pressured heart vessels could have resulted in myocardial vessel rupture - the same pathophysiologic mechanism that underlies the appearance of subendocardial hemorrhages. If this man was conscious and aware for some time prior and upon initial compression, the fight or flight response could have resulted in a sudden surge of circulating catecholamine levels - which is the second described mechanism of subendocardial hemorrhage development. However, we believe that autopsy findings favor the firstly described scenario. Nevertheless, subendocardial hemorrhages are out of the common finding in crush asphyxia.
    MeSH term(s) Male ; Humans ; Adult ; Asphyxia/etiology ; Heart Diseases ; Hemorrhage/etiology ; Vascular Diseases ; Autopsy
    Language English
    Publishing date 2023-02-27
    Publishing country England
    Document type Case Reports
    ZDB-ID 2268721-X
    ISSN 1878-7487 ; 1752-928X
    ISSN (online) 1878-7487
    ISSN 1752-928X
    DOI 10.1016/j.jflm.2023.102506
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  4. Article ; Online: Burn index, burn characteristics and carboxyhemoglobin levels in indoor fire-related deaths: Significance and interpretation of the autopsy findings.

    Leković, Aleksa / Nikolić, Slobodan / Djukić, Danica / Živković, Vladimir

    Forensic science international

    2023  Volume 345, Page(s) 111618

    Abstract: Introduction: The Burn Index (BI) is a significant clinical prognostic parameter for patients with burns. It simultaneously considers major mortality risk factors: age and burns extensivity. Despite the inability to distinguish between ante- and post- ... ...

    Abstract Introduction: The Burn Index (BI) is a significant clinical prognostic parameter for patients with burns. It simultaneously considers major mortality risk factors: age and burns extensivity. Despite the inability to distinguish between ante- and post-mortem burns, their characteristics on autopsy might indicate if a significant thermal injury occurred before the onset of death. We investigated whether autopsy BI, burn extensivity, and severity could tell whether burns were the concurrent cause of fire-related death (FRD), even if the body remained in a fire.
    Material and methods: Ten-year retrospective study analyzed FRD that occurred at the scene in a confined space. Soot aspiration was the main inclusion criterion. Autopsy reports were reviewed for demographic data, burn characteristics (degree, Total Body Surface Area burned- TBSA), coronary artery disease, and blood ethanol. We calculated the BI as a sum of the victim's age and percentage of TBSA affected by 2nd, 3rd and 4th-degree burns. Cases were divided into two groups: those with COHb≤ 30% and with COHb> 30%. Subjects with burned TBSA≤ 40% were analyzed separately afterward.
    Results: The study included 53 males (71.6%) and 21 females (28.4%). No significant difference in age was observed between groups (p > 0.05). COHb≤ 30% had 33, and COHb> 30% had 41 victims. BI and burns extensivity (TBSA) had significant negative correlation with COHb values (ρ = -0.581, p < 0.01 and ρ = -0.439, p < 0.01, respectively). Both were significantly higher in subjects with COHb≤ 30% compared to those with COHb> 30% (140.7 ± 29.57 vs. 95.49 ± 38.49, p < 0.01 and 98 (13-100) vs. 30 (0-100), p < 0.01, BI and TBSA respectively). BI had excellent and TBSA fair performance for detection of subjects with COHb≤ 30% on ROC curve analysis (AUCs 0.821, p < 0.001 and 0.765, p < 0.001), with optimal cut-off values: BI≥ 107 (sensitivity 81.3%, specificity 70.7%) and TBSA≥ 45 (sensitivity 84.8%, specificity 70.7%). On logistic regression analysis BI≥ 107 was independently associated with COHb≤ 30% values (aOR 6; 95%CI 1.55-23.37). The same holds for the presence of 3rd-degree burns (aOR 5.9; 95%CI 1.45-23.99). In the subgroup of subjects with TBSA≤ 40% burned, those with COHb≤ 50% were significantly older than victims with COHb> 50% (p < 0.05). Here BI≥ 85 was a particularly good predictor for detection of subjects with COHb≤ 50% (AUC=0.913, p < 0.001, 95% CI 0.813-1.00; sensitivity 90.9%, specificity 81%).
    Conclusion: The BI≥ 107, TBSA≥ 45% burned, and 3rd-degree burns observed on autopsy point to a significantly higher odds that limited CO intoxication occurred, and burns should be considered a concurrent cause of indoor FRD. When less than 40% of TBSA was affected, BI≥ 85 indicated sub-lethal CO poisoning.
    MeSH term(s) Male ; Female ; Humans ; Carboxyhemoglobin/analysis ; Retrospective Studies ; Autopsy ; Fires ; Burns
    Chemical Substances Carboxyhemoglobin (9061-29-4)
    Language English
    Publishing date 2023-02-27
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 424042-x
    ISSN 1872-6283 ; 0379-0738
    ISSN (online) 1872-6283
    ISSN 0379-0738
    DOI 10.1016/j.forsciint.2023.111618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Commentary on the "Entrapment within an ottoman storage bed: an unusual accidental asphyxial death": the complex asphyxiation.

    Leković, Aleksa / Živković, Vladimir / Nikolić, Slobodan

    Forensic science, medicine, and pathology

    2022  Volume 18, Issue 3, Page(s) 382–384

    MeSH term(s) Humans ; Asphyxia/etiology
    Language English
    Publishing date 2022-07-09
    Publishing country United States
    Document type Letter
    ZDB-ID 2195904-3
    ISSN 1556-2891 ; 1547-769X
    ISSN (online) 1556-2891
    ISSN 1547-769X
    DOI 10.1007/s12024-022-00500-6
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  6. Article: Blood Transfusion Procedure: Assessment of Serbian Intensive Care Nurses' Knowledge.

    Simin, Dragana / Dolinaj, Vladimir / Brestovački Svitlica, Branislava / Grujić, Jasmina / Živković, Dragana / Milutinović, Dragana

    Healthcare (Basel, Switzerland)

    2024  Volume 12, Issue 7

    Abstract: Many patients require administering one or more blood components during hospitalisation in the Intensive Care Unit (ICU). Therefore, nurses' knowledge of who is responsible for immediately administering blood transfusions, monitoring patients, and ... ...

    Abstract Many patients require administering one or more blood components during hospitalisation in the Intensive Care Unit (ICU). Therefore, nurses' knowledge of who is responsible for immediately administering blood transfusions, monitoring patients, and identifying and managing transfusion reactions is crucial. This cross-sectional descriptive-analytical study aimed to assess the knowledge of ICU nurses in tertiary healthcare institutions about blood transfusion procedures. The questionnaire about the transfusion procedure was designed and reviewed by experts. The questionnaire consisted of 29 items divided into three domains. The scores on the knowledge test ranged from 10 to 27. Generally, 57.7% of nurses had moderate, 23.4% low, and 18.9% high levels of knowledge about the transfusion procedure. Most nurses answered correctly about refreezing fresh frozen plasma, verifying the transfusion product, and identifying the patient. Of the nurses, 91.0% would recognise mild allergic reactions, and 98.2% knew about the supervision of sedated patients. Nurses showed poor knowledge of the length of usage of the same transfusion system for red blood cells, labelling, and transfusion administration in febrile patients. Nurses with higher education and longer working experience had significantly better outcomes (
    Language English
    Publishing date 2024-03-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare12070720
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  7. Article ; Online: Unusual suicidal penetrating heart injury by captive-bolt gunshot.

    Nikolić, Slobodan / Atanasijević, Tatjana / Živković, Vladimir

    Forensic science, medicine, and pathology

    2022  Volume 18, Issue 3, Page(s) 260–263

    Abstract: We present a case of a 56-year-old man who committed suicide using a captive-bolt gun, pressed against the left side of his chest. As the victim worked as a butcher, slaughtering livestock, he owned a captive-bolt gun. Just before committing suicide, he ... ...

    Abstract We present a case of a 56-year-old man who committed suicide using a captive-bolt gun, pressed against the left side of his chest. As the victim worked as a butcher, slaughtering livestock, he owned a captive-bolt gun. Just before committing suicide, he received a disturbing phone call from a person to whom he owed money. The autopsy revealed a 12-mm wound in the left pectoral region with two symmetrical, oval soot deposits. The wound extended through the fifth left rib, the pericardium, and the inferior portion of the anterior wall of the left ventricle. There was a partial-thickness tear in the left aspect of the interventricular septum with associated contusion. About 300 ml of the blood was found within the pericardial sack and about 1200 ml in the left pleural cavity. Atypical location (left chest vs. head), absence of previous suicide attempts and suicide note, and the apparent immediate provoking event suggest abrupt rather than premeditated suicide.
    MeSH term(s) Male ; Humans ; Middle Aged ; Head Injuries, Penetrating ; Suicidal Ideation ; Soot ; Wounds, Gunshot ; Heart Injuries/etiology
    Chemical Substances Soot
    Language English
    Publishing date 2022-01-31
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2195904-3
    ISSN 1556-2891 ; 1547-769X
    ISSN (online) 1556-2891
    ISSN 1547-769X
    DOI 10.1007/s12024-021-00456-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: URINARY INCONTINENCE - FROM CHILDHOOD ONWARDS.

    Živković, Dragana / Franić, Damir / Kojović, Vladimir

    Acta clinica Croatica

    2022  Volume 61, Issue 1, Page(s) 115–123

    Abstract: Urinary incontinence (UI) is a condition that affects patients of all ages, starting with childhood. There are two peaks in its incidence, i.e., in childhood and another one in patients over 40 years of age, which increases continuously with patient age. ...

    Abstract Urinary incontinence (UI) is a condition that affects patients of all ages, starting with childhood. There are two peaks in its incidence, i.e., in childhood and another one in patients over 40 years of age, which increases continuously with patient age. It is a condition recognized by the World Health Organization as a set of diseases (International Classification of Diseases, ICD-10), and the International Classification of Functionality recognizes the associated extreme disablement. UI is a major health problem affecting the lives of an estimated 400 million persons worldwide. The global aging of the population will cause rise in the incidence of UI in the future. It is expected that UI itself will become a serious health and social burden for both patients and health service providers. UI can be an isolated problem, or it can be associated and/or aggravated by any associated disorder affecting the nervous system such as myelomeningoceles, Parkinson's disease or stroke. UI often affects the patient daily life, and it can have repercussions on their physical, financial, social, and emotional well-being. At last, it has a negative influence on their sexual health.
    MeSH term(s) Humans ; Adult ; Middle Aged ; Prevalence ; Urinary Incontinence/epidemiology ; Urinary Incontinence/etiology ; Urinary Incontinence/psychology ; Aging
    Language English
    Publishing date 2022-10-29
    Publishing country Croatia
    Document type Journal Article ; Review
    ZDB-ID 1478635-7
    ISSN 1333-9451 ; 0353-9466
    ISSN (online) 1333-9451
    ISSN 0353-9466
    DOI 10.20471/acc.2022.61.01.14
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  9. Article ; Online: A comprehensive proteomics analysis of the response of

    Izrael Živković, Lidija / Hüttmann, Nico / Susevski, Vanessa / Medić, Ana / Beškoski, Vladimir / Berezovski, Maxim V / Minić, Zoran / Živković, Ljiljana / Karadžić, Ivanka

    Nanotoxicology

    2023  Volume 17, Issue 1, Page(s) 20–41

    Abstract: The increased commercial use and spread of nanoceria raises concerns about the risks associated with its effects on living organisms. ... ...

    Abstract The increased commercial use and spread of nanoceria raises concerns about the risks associated with its effects on living organisms. Although
    MeSH term(s) Humans ; Pseudomonas aeruginosa ; Pyocyanine/metabolism ; Proteomics ; Bacterial Proteins/metabolism
    Chemical Substances ceric oxide (619G5K328Y) ; Pyocyanine (9OQM399341) ; Bacterial Proteins
    Language English
    Publishing date 2023-03-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2237988-5
    ISSN 1743-5404 ; 1743-5390
    ISSN (online) 1743-5404
    ISSN 1743-5390
    DOI 10.1080/17435390.2023.2180451
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  10. Article ; Online: Regarding "The ongoing loss of historical material from institutions".

    Nikolić, Slobodan / Cvetković, Danica / Živković, Vladimir

    Forensic science, medicine, and pathology

    2021  Volume 17, Issue 2, Page(s) 375

    Language English
    Publishing date 2021-05-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2195904-3
    ISSN 1556-2891 ; 1547-769X
    ISSN (online) 1556-2891
    ISSN 1547-769X
    DOI 10.1007/s12024-021-00365-1
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