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  1. Article: Gut dysbiosis in alcoholic liver disease: Wonderful dilemma?

    Abenavoli, Ludovico / Scarpellini, Emidio

    Annals of hepatology

    2023  Volume 28, Issue 5, Page(s) 101123

    MeSH term(s) Humans ; Dysbiosis ; Liver Diseases, Alcoholic ; Intestinal Mucosa ; Non-alcoholic Fatty Liver Disease/diagnosis ; Liver
    Language English
    Publishing date 2023-06-02
    Publishing country Mexico
    Document type Editorial
    ZDB-ID 2188733-0
    ISSN 1665-2681
    ISSN 1665-2681
    DOI 10.1016/j.aohep.2023.101123
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6221: Show issues Location:
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  2. Article ; Online: Gut Microbiota According to the Metabolome.

    Scarpellini, Emidio / Rinninella, Emanuele

    Nutrients

    2023  Volume 15, Issue 22

    Abstract: The human gut microbiota is an ecosystem harboring trillions of microorganisms, encompassing bacteria, viruses, archaea, fungi, and protozoa [ ... ]. ...

    Abstract The human gut microbiota is an ecosystem harboring trillions of microorganisms, encompassing bacteria, viruses, archaea, fungi, and protozoa [...].
    MeSH term(s) Humans ; Bacteria ; Fungi ; Gastrointestinal Microbiome ; Metabolome
    Language English
    Publishing date 2023-11-13
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15224768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Gut dysbiosis in alcoholic liver disease

    Ludovico Abenavoli / Emidio Scarpellini

    Annals of Hepatology, Vol 28, Iss 5, Pp 101123- (2023)

    Wonderful dilemma?

    2023  

    Keywords Gut microbiota ; Liver disease ; Cirrhosis ; Ecosystem ; Specialties of internal medicine ; RC581-951
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Post-COVID-19 Gastro-Intestinal Disturbances.

    Scarpellini, Emidio / Tack, Jan

    Reviews on recent clinical trials

    2022  Volume 18, Issue 1, Page(s) 34–40

    Abstract: Background: Since the end of 2019, SARS-CoV-2 has been responsible for the multisystemic hyper-inflammatory disease, namely, COVID-19, as a majorly impactful pandemic. Gastrointestinal (GI) symptoms occurring during and after disease are gaining ... ...

    Abstract Background: Since the end of 2019, SARS-CoV-2 has been responsible for the multisystemic hyper-inflammatory disease, namely, COVID-19, as a majorly impactful pandemic. Gastrointestinal (GI) symptoms occurring during and after disease are gaining increasing attention among experts.
    Methods: We briefly review and comment on preliminary and recent evidences on prevalence, pathophysiology, and perspective treatment options for GI disturbances during and after COVID-19.
    Results: Several reports from the literature show a significant portion of COVID-19 patients suffering from GI symptoms both at the early stages of the disease and after the end of it, sometimes for several months, namely "long-COVID-19" patients, irrespective of vaccination. An unsolved issue regarding COVID-19 is the association between GI symptoms and the outcome of COVID-19 patients. Several studies and metanalyses suggest a worse evolution of COVID-19 in patients presenting with GI symptoms. However, these data have not been agreed. Indeed, only one uniform observation can be found in the literature: patients with chronic liver disease have a worse outcome from COVID-19 infection. Upper and lower GI symptoms have similarities with postinfectious functional dyspepsia (FD) and irritable bowel syndrome (IBS). FD and IBS following infection are recognize as pathophysiological factor the gut microbial, which is a gut microbial quali- and quantitative unbalance, namely dysbiosis. Furthermore, several preliminary reports and ongoing clinical trials have shown gut microbiota modulation by pre-, pro- and postbiotics to be effective in changing and preventing COVID-19 natural course.
    Conclusion: GI symptoms characterize both long- and non-long-COVID-19 with a potentially significant impact on its natural course. Gut microbiota modulation seems to be a sensible target for disease treatment and/or prevention.
    MeSH term(s) Humans ; Irritable Bowel Syndrome/complications ; Irritable Bowel Syndrome/diagnosis ; Irritable Bowel Syndrome/therapy ; COVID-19/complications ; SARS-CoV-2 ; Gastrointestinal Diseases/etiology ; Gastrointestinal Diseases/diagnosis ; Dyspepsia
    Language English
    Publishing date 2022-12-04
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2251879-4
    ISSN 1876-1038 ; 1574-8871
    ISSN (online) 1876-1038
    ISSN 1574-8871
    DOI 10.2174/1574887118666221201104833
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6436: Show issues Location:
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  5. Article ; Online: The role of gut microbiota in gastrointestinal diseases: the heart of the matter.

    Abenavoli, Ludovico / Scarpellini, Emidio / Luzza, Francesco

    Minerva gastroenterology

    2022  Volume 67, Issue 4, Page(s) 312–313

    MeSH term(s) Gastrointestinal Diseases ; Gastrointestinal Microbiome ; Heart ; Humans ; Microbiota
    Language English
    Publishing date 2022-01-17
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062713-8
    ISSN 2724-5365
    ISSN (online) 2724-5365
    DOI 10.23736/S2724-5985.21.03022-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Are probiotics effective in reversing non-alcoholic steatohepatitis?

    Abenavoli, Ludovico / Boccuto, Luigi / Scarpellini, Emidio

    Hepatobiliary surgery and nutrition

    2021  Volume 10, Issue 3, Page(s) 407–409

    Language English
    Publishing date 2021-06-22
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-21-85
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Human Genes Involved in the Interaction between Host and Gut Microbiome: Regulation and Pathogenic Mechanisms.

    Boccuto, Luigi / Tack, Jan / Ianiro, Gianluca / Abenavoli, Ludovico / Scarpellini, Emidio

    Genes

    2023  Volume 14, Issue 4

    Abstract: Introduction: The umbrella term "human gut microbiota" describes the complex ecosystem harboring our gut. It includes bacteria, viruses, protozoa, archaea, fungi, and yeasts. This taxonomic classification does not describe its functions, which encompass ...

    Abstract Introduction: The umbrella term "human gut microbiota" describes the complex ecosystem harboring our gut. It includes bacteria, viruses, protozoa, archaea, fungi, and yeasts. This taxonomic classification does not describe its functions, which encompass nutrients digestion and absorption, immune system regulation, and host metabolism. "Gut microbiome" indicates instead the genome belonging to these "microbes" actively involved in these functions. However, the interaction between the host genome and the microbial ones determines the fine functioning of our organism.
    Methods: We reviewed the data available in the scientific literature on the definition of gut microbiota, gut microbiome, and the data on human genes involved in the interaction with the latter. We consulted the main medical databases using the following keywords, acronyms, and their associations: gut microbiota, gut microbiome, human genes, immune function, and metabolism.
    Results: Candidate human genes encoding enzymes, inflammatory cytokines, and proteins show similarity with those included in the gut microbiome. These findings have become available through newer artificial intelligence (AI) algorithms allowing big data analysis. From an evolutionary point of view, these pieces of evidence explain the strict and sophisticated interaction at the basis of human metabolism and immunity regulation in humans. They unravel more and more physiopathologic pathways included in human health and disease.
    Discussion: Several lines of evidence also obtained through big data analysis support the bi-directional role of gut microbiome and human genome in host metabolism and immune system regulation.
    MeSH term(s) Humans ; Gastrointestinal Microbiome/genetics ; Artificial Intelligence ; Microbiota ; Immune System ; Biological Evolution
    Language English
    Publishing date 2023-03-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes14040857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Microbiota-Gastric Cancer Interactions and the Potential Influence of Nutritional Therapies.

    Raoul, Pauline / Maccauro, Valeria / Cintoni, Marco / Scarpellini, Emidio / Ianiro, Gianluca / Gasbarrini, Antonio / Mele, Maria Cristina / Rinninella, Emanuele

    International journal of molecular sciences

    2024  Volume 25, Issue 3

    Abstract: Gastric cancer (GC) is one of the most common causes of cancer deaths, and GC treatments represent a large area of research. Although initially regarded as a sterile organ and unsuitable for microbial communities, the discovery ... ...

    Abstract Gastric cancer (GC) is one of the most common causes of cancer deaths, and GC treatments represent a large area of research. Although initially regarded as a sterile organ and unsuitable for microbial communities, the discovery of
    MeSH term(s) Humans ; Stomach Neoplasms/metabolism ; Gastric Mucosa/metabolism ; Microbiota ; Helicobacter pylori ; Helicobacter Infections/microbiology
    Language English
    Publishing date 2024-01-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25031679
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  9. Article ; Online: Reply to: Late dumping syndrome or postprandial reactive hypoglycaemic syndrome after bariatric surgery.

    Scarpellini, Emidio / Arts, Joris / Vanuytsel, Tim / Tack, Jan

    Nature reviews. Endocrinology

    2021  Volume 17, Issue 5, Page(s) 317–318

    MeSH term(s) Bariatric Surgery/adverse effects ; Consensus ; Dumping Syndrome/diagnosis ; Dumping Syndrome/etiology ; Humans ; Hypoglycemia/etiology ; Hypoglycemic Agents
    Chemical Substances Hypoglycemic Agents
    Language English
    Publishing date 2021-02-03
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2489381-X
    ISSN 1759-5037 ; 1759-5029
    ISSN (online) 1759-5037
    ISSN 1759-5029
    DOI 10.1038/s41574-021-00474-5
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    In stock of ZB MED Cologne/Königswinter

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  10. Article ; Online: Ultrasound Prevalence and Clinical Features of Nonalcoholic Fatty Liver Disease in Patients with Inflammatory Bowel Diseases: A Real-Life Cross-Sectional Study.

    Abenavoli, Ludovico / Spagnuolo, Rocco / Scarlata, Giuseppe Guido Maria / Scarpellini, Emidio / Boccuto, Luigi / Luzza, Francesco

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 11

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Humans ; Male ; Female ; Non-alcoholic Fatty Liver Disease/complications ; Non-alcoholic Fatty Liver Disease/diagnostic imaging ; Non-alcoholic Fatty Liver Disease/epidemiology ; Cross-Sectional Studies ; Risk Factors ; Retrospective Studies ; Prevalence ; Inflammatory Bowel Diseases/complications ; Inflammatory Bowel Diseases/diagnostic imaging ; Inflammatory Bowel Diseases/epidemiology ; Crohn Disease/complications ; Colitis, Ulcerative/complications ; Colitis, Ulcerative/diagnostic imaging ; Colitis, Ulcerative/epidemiology ; Inflammation/complications
    Language English
    Publishing date 2023-11-01
    Publishing country Switzerland
    Document type Observational Study ; Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59111935
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    Zs.A 6270: Show issues Location:
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