Article ; Online: A prospective study examining the effect of dienogest treatment on endometrioma size and symptoms.
2022 Volume 38, Issue 5, Page(s) 403–406
Abstract: Objective: We aimed to determine the effect of dienogest on cyst volume, symptoms, and quality of life in patients with endometrioma.: Method: This prospective cohort study included 37 patients diagnosed with endometrioma and planned for medical ... ...
| Abstract | Objective: We aimed to determine the effect of dienogest on cyst volume, symptoms, and quality of life in patients with endometrioma. Method: This prospective cohort study included 37 patients diagnosed with endometrioma and planned for medical treatment. Subjects were treated with a 3-month oral dose of dienogest 2 mg/day. Pre-treatment and post-treatment endometriosis measurements were assessed via 3D ultrasonography, pain symptoms via 100-mm visual analog scale (VAS), and quality of life via Short Form-36. Results: The mean age of the patients was 36.0 ± 6.6 years. The mean endometrioma volume was significantly reduced by 31% after treatment (26.7 ± 19.7 mm Conclusion: Our findings showed dienogest treatment at oral doses of 2 mg/day for 3 months significantly reducing the size of endometrioma, reducing pain level, and increasing quality of life in women with endometriosis. |
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| MeSH term(s) | Adult ; Endometriosis/complications ; Endometriosis/drug therapy ; Female ; Humans ; Nandrolone/analogs & derivatives ; Pelvic Pain/drug therapy ; Pelvic Pain/etiology ; Prospective Studies ; Quality of Life ; Treatment Outcome |
| Chemical Substances | dienogest (46M3EV8HHE) ; Nandrolone (6PG9VR430D) |
| Language | English |
| Publishing date | 2022-03-23 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 639237-4 |
| ISSN | 1473-0766 ; 0951-3590 |
| ISSN (online) | 1473-0766 |
| ISSN | 0951-3590 |
| DOI | 10.1080/09513590.2022.2053956 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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