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Article ; Online: Use of a pharmacy-based GP video consultation service: a mixed methods study.

Parsons, Joanne / Rahman, Sameur / Bryce, Carol / Atherton, Helen

2022 Volume 40, Issue 2, Page(s) 241–247

Abstract: Background: Little is known about private general practice appointment services offered via video. This study aimed to explore which patients are using a video pharmacy-based general practitioner (GP) appointment service, including patterns of use, ... ...

Abstract	Background: Little is known about private general practice appointment services offered via video. This study aimed to explore which patients are using a video pharmacy-based general practitioner (GP) appointment service, including patterns of use, reasons for using the service, and satisfaction with the service. Methods: Descriptive statistics and parametric and nonparametric tests were used to conduct a retrospective cross-sectional analysis of routinely collected data on consultations, and postconsultation questionnaires. Interviews were conducted with patients and GPs. Results: A total of 7,928 consultations were included in the analysis. More than half of appointments were booked for the same day, with lunchtime appointments being popular. The most common health condition was respiratory conditions, and 9% of consultations were used by patients using the service more than once. At least one prescription was issued in over half of all consultations. Overall, satisfactions of consultations were high. Conclusions: The characteristics of those patients using the video consultation service match data on who uses online services in general practice. This study shows that some patients are willing to pay to use this private service because they feel it is more convenient, NHS services do not have capacity to see them at the time they need, or they do not have access to regular GP services.
MeSH term(s)	Humans ; General Practitioners ; Cross-Sectional Studies ; Retrospective Studies ; Referral and Consultation ; Telemedicine ; Pharmacy
Language	English
Publishing date	2022-09-28
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	605939-9
ISSN	1460-2229 ; 0263-2136
ISSN (online)	1460-2229
ISSN	0263-2136
DOI	10.1093/fampra/cmac101
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Article ; Online: Longitudinal associations among the Big Five personality traits and healthcare utilization in the U.S.

Atherton, Olivia E / Willroth, Emily C / Weston, Sara J / Mroczek, Daniel K / Graham, Eileen K

Social science & medicine (1982)

2023 Volume 340, Page(s) 116494

Abstract: Objective: One critical component of individual and public health is healthcare utilization, or the extent to which individuals have routine check-ups, schedule treatments, or use emergency services. However, we know little about who uses healthcare ... ...

Abstract	Objective: One critical component of individual and public health is healthcare utilization, or the extent to which individuals have routine check-ups, schedule treatments, or use emergency services. However, we know little about who uses healthcare services and what types, the conditions that exacerbate utilization, or the factors that explain why people seek out services. The present study fills these gaps in the literature by investigating the role of personality factors in predicting various forms of healthcare utilization, how these associations vary by age, socioeconomic resources, and chronic conditions, as well as one potential psychological mediating mechanism (i.e., sense of control). Methods: We use data from a large longitudinal sample of Americans (N = 7108), with three assessments spanning 20 years. Participants reported on their Big Five personality traits using the Midlife Development Inventory, healthcare utilization across three domains (routine visits, scheduled treatment, urgent care), age, income, insurance, chronic conditions, and sense of control. Results: Multilevel models showed that people who were more agreeable and neurotic tended to use more healthcare services. Moreover, on occasions when people were more extraverted and open, they tended to use more healthcare services. There were several nuances in personality-healthcare utilization associations depending on the type of healthcare service, age, and socioeconomic resources. Longitudinal mediation analyses demonstrated sense of control as one mechanism linking personality traits to healthcare utilization in the U.S. Conclusions: We discuss the theoretical and practical implications of interactions between individuals and structural systems for promoting the health of aging U.S. Americans.
MeSH term(s)	Humans ; Aging/psychology ; Personality ; Delivery of Health Care ; Patient Acceptance of Health Care ; Chronic Disease ; Longitudinal Studies
Language	English
Publishing date	2023-12-11
Publishing country	England
Document type	Journal Article
ZDB-ID	4766-1
ISSN	1873-5347 ; 0037-7856 ; 0277-9536
ISSN (online)	1873-5347
ISSN	0037-7856 ; 0277-9536
DOI	10.1016/j.socscimed.2023.116494
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Article ; Online: Should patients with heart failure listen to their gut?

Atherton, John J / Punyadeera, Chamindie

The Medical journal of Australia

2020 Volume 213, Issue 8, Page(s) 357–358

MeSH term(s)	Gastrointestinal Microbiome ; Heart Failure ; Humans ; Methylamines ; Prognosis
Chemical Substances	Methylamines ; trimethyloxamine (FLD0K1SJ1A)
Language	English
Publishing date	2020-09-29
Publishing country	Australia
Document type	Editorial ; Comment
ZDB-ID	186082-3
ISSN	1326-5377 ; 0025-729X
ISSN (online)	1326-5377
ISSN	0025-729X
DOI	10.5694/mja2.50797
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Article ; Online: Spontaneous Anchoring-Mediated Topography of an Orientable Fluid.

Ferris, Andrew J / Rosenblatt, Charles / Atherton, Timothy J

Physical review letters

2021 Volume 126, Issue 5, Page(s) 57803

Abstract: A topography in a Newtonian fluid occurs if there is a disturbance near the surface. But what if there is no such disturbance? We show by optical profilometry that a thin nematic film resting on a topological-defect-patterned substrate can exhibit a hill ...

Abstract	A topography in a Newtonian fluid occurs if there is a disturbance near the surface. But what if there is no such disturbance? We show by optical profilometry that a thin nematic film resting on a topological-defect-patterned substrate can exhibit a hill or divot at the opposing free (air) interface in the absence of a topological disturbance at that interface. We propose a model that incorporates several material properties and that predicts the major experimental features. This work demonstrates the importance of, in particular, anisotropic surface interactions in the creation of a free-surface topography.
Language	English
Publishing date	2021-02-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.126.057803
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Article ; Online: An energy-optimization method to study gel-swelling in confinement.

Joshi, Chaitanya / Giso, Mathew Q / Louf, Jean-François / Datta, Sujit S / Atherton, Timothy J

Soft matter

2023 Volume 19, Issue 37, Page(s) 7184–7191

Abstract: We recast the problem of hydrogel swelling under physical constraints as an energy optimization problem. We apply this approach to compute equilibrium shapes of hydrogel spheres confined within a jammed matrix of rigid beads and interpret the results to ... ...

Abstract	We recast the problem of hydrogel swelling under physical constraints as an energy optimization problem. We apply this approach to compute equilibrium shapes of hydrogel spheres confined within a jammed matrix of rigid beads and interpret the results to determine how confinement modifies the mechanics of swollen hydrogels. In contrast to the unconfined case, we find a spatial separation of strains within the bulk of the hydrogel as the strain becomes localized to an outer region. We also explore the contact mechanics of the gel, finding a transition from Hertzian behavior to non-Hertzian behavior as a function of swelling. Our model, implemented in the
Language	English
Publishing date	2023-09-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2191476-X
ISSN	1744-6848 ; 1744-683X
ISSN (online)	1744-6848
ISSN	1744-683X
DOI	10.1039/d3sm00465a
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Article ; Online: The asymptomatic follicular lymphoma (AFL) trial: single-agent rituximab immunotherapy versus 90Y-ibritumomab tiuxetan radioimmunotherapy (RIT) for patients with new, untreated follicular lymphoma.

Laoruangroj, Chonlada / Atherton, Pamela J / Wiseman, Gregory A / Ansell, Stephen / Feldman, Andrew L / Schumacher, Peyton / Witzig, Thomas E

Leukemia & lymphoma

2024 Volume 65, Issue 3, Page(s) 333–338

Abstract: Patients with asymptomatic follicular lymphoma (AFL) are candidates for observation or immunotherapy. Given the effectiveness of radiation therapy in FL, another option is 90Yttrium-ibritumomab tiuxetan radioimmunotherapy (RIT). We conducted a trial ... ...

Abstract	Patients with asymptomatic follicular lymphoma (AFL) are candidates for observation or immunotherapy. Given the effectiveness of radiation therapy in FL, another option is 90Yttrium-ibritumomab tiuxetan radioimmunotherapy (RIT). We conducted a trial where untreated AFL patients were randomized to rituximab 375 mg/m2 weekly × 4 or rituximab 250 mg/m
MeSH term(s)	Humans ; Rituximab/therapeutic use ; Lymphoma, Follicular/diagnosis ; Lymphoma, Follicular/therapy ; Radioimmunotherapy ; Yttrium Radioisotopes/therapeutic use ; Lymphoma, Non-Hodgkin/therapy ; Treatment Outcome ; Antibodies, Monoclonal
Chemical Substances	Rituximab (4F4X42SYQ6) ; ibritumomab tiuxetan (4Q52C550XK) ; Yttrium-90 (1K8M7UR6O1) ; Yttrium Radioisotopes ; Antibodies, Monoclonal
Language	English
Publishing date	2024-01-08
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1042374-6
ISSN	1029-2403 ; 1042-8194
ISSN (online)	1029-2403
ISSN	1042-8194
DOI	10.1080/10428194.2023.2295792
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Article ; Online: Uptake and User Characteristics for Pharmacy-Based Contraception and Chlamydia Treatment: A Quantitative Retrospective Study from the UK.

Gauly, Julia / Atherton, Helen / Ross, Jonathan D C

Pharmacy (Basel, Switzerland)

2021 Volume 9, Issue 1

Abstract: The health provider Umbrella delivers several SRHS through more than 120 pharmacies in Birmingham (England). Umbrella pharmacy data collected between August 2015 and August 2018 were used to descriptively analyse the uptake and user characteristics for ... ...

Abstract	The health provider Umbrella delivers several SRHS through more than 120 pharmacies in Birmingham (England). Umbrella pharmacy data collected between August 2015 and August 2018 were used to descriptively analyse the uptake and user characteristics for emergency contraception, short-acting oral contraception, condoms and chlamydia treatment. In total, 54,309 pharmacy visits were analysed. A total of 30,473 females presented for emergency contraception. Most were supplied with an emergency contraceptive pill (98.6%, 30,052 out of 30,473), which was levonorgestrel in 57.4% of cases (17,255 out of 30,052). Of those females who attended for short-acting oral contraception, 54.3% (1764 out of 3247) were provided with the progesterone-only pill. Of those who were given chlamydia treatment, the majority received doxycycline (76.8%, 454 out of 591). A total of 74% (14,888 out of 19,998) of those who requested condoms were not provided with specific instructions on their use. Pharmacies have the potential to make a substantial contribution to the delivery of an integrated sexual health service including rapid access to emergency contraception, convenient delivery of short-acting hormonal contraception and treatment of chlamydia. Appropriate education, support and audit is required to ensure the delivery of high-quality care.
Language	English
Publishing date	2021-03-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2737194-3
ISSN	2226-4787 ; 2226-4787
ISSN (online)	2226-4787
ISSN	2226-4787
DOI	10.3390/pharmacy9010061
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Article ; Online: Which patients miss appointments with general practice and the reasons why: a systematic review.

Parsons, Joanne / Bryce, Carol / Atherton, Helen

The British journal of general practice : the journal of the Royal College of General Practitioners

2021 Volume 71, Issue 707, Page(s) e406–e412

Abstract: Background: Missed GP appointments have considerable time and cost implications for healthcare services.: Aim: This systematic review aims to explore the rate of missed primary care appointments, what the reported reasons are for appointments being ... ...

Abstract	Background: Missed GP appointments have considerable time and cost implications for healthcare services. Aim: This systematic review aims to explore the rate of missed primary care appointments, what the reported reasons are for appointments being missed, and which patients are more likely to miss appointments. Design and setting: This study reports the findings of a systematic review. The included studies report the rate or reasons of missed appointments in a primary care setting. Method: Databases were searched using a pre-defined search strategy. Eligible studies were selected for inclusion based on detailed inclusion criteria through title, abstract, and full text screening. Quality was assessed on all included studies, and findings were synthesised to answer the research questions. Results: A total of 26 studies met the inclusion criteria for the review. Of these, 19 reported a rate of missed appointments. The mean rate of missed appointments was 15.2%, with a median of 12.9%. Twelve studies reported a reason that appointments were missed, with work or family/childcare commitments, forgetting the appointment, and transportation difficulties most commonly reported. In all, 20 studies reported characteristics of people likely to miss appointments. Patients who were likely to miss appointments were those from minority ethnicity, low sociodemographic status, and younger patients ( Conclusion: Findings from this review have potential implications for targeted interventions to address missed appointments in primary care. This is the first step for clinicians to be able to target interventions to reduce the rate of missed appointments.
MeSH term(s)	Appointments and Schedules ; Family Practice ; General Practice ; Humans ; Primary Health Care ; Text Messaging
Language	English
Publishing date	2021-05-27
Publishing country	England
Document type	Journal Article ; Systematic Review
ZDB-ID	1043148-2
ISSN	1478-5242 ; 0035-8797 ; 0960-1643
ISSN (online)	1478-5242
ISSN	0035-8797 ; 0960-1643
DOI	10.3399/BJGP.2020.1017
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Article ; Online: Exaggerated myocardial torsion may contribute to dynamic left ventricular outflow tract obstruction in hypertrophic cardiomyopathy.

Lo, Ada K C / Mew, Thomas / Mew, Christina / Guppy-Coles, Kristyan / Dahiya, Arun / Ng, Arnold / Prasad, Sandhir / Atherton, John J

European heart journal open

2023 Volume 3, Issue 4, Page(s) oead043

Abstract: Aims: Dynamic left ventricular (LV) outflow tract obstruction (LVOTO) is associated with symptoms and increased risk of developing heart failure in hypertrophic cardiomyopathy (HCM). The association of LVOTO and LV twist mechanics has not been well ... ...

Abstract	Aims: Dynamic left ventricular (LV) outflow tract obstruction (LVOTO) is associated with symptoms and increased risk of developing heart failure in hypertrophic cardiomyopathy (HCM). The association of LVOTO and LV twist mechanics has not been well studied in HCM. The aim of the study was to compare the pattern of LV twist in patients with HCM associated with asymmetrical septal hypertrophy with and without LVOTO. Methods and results: Echocardiography (including speckle tracking) was performed in 212 patients with HCM, divided according to the absence ( Conclusion: This study demonstrates that increased peak LV twist is independently associated with LVOTO in patients with HCM. Peak twist was similarly exaggerated in patients with only latent LVOTO, suggesting that it may play a contributory role to LVOTO in HCM.
Language	English
Publishing date	2023-08-01
Publishing country	England
Document type	Journal Article
ISSN	2752-4191
ISSN (online)	2752-4191
DOI	10.1093/ehjopen/oead043
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Article ; Online: Endemic coronavirus infections are associated with strong homotypic immunity in a US cohort of children from birth to 4 years.

Morrow, Ardythe L / Payne, Daniel C / Conrey, Shannon C / McMorrow, Meredith / McNeal, Monica M / Niu, Liang / Burrell, Allison R / Schlaudecker, Elizabeth P / Mattison, Claire / Burke, Rachel M / DeFranco, Emily / Teoh, Zheyi / Wrammert, Jens / Atherton, Lydia J / Thornburg, Natalie J / Staat, Mary A

Journal of the Pediatric Infectious Diseases Society

2024

Abstract: Background: The endemic coronaviruses OC43, HKU1, NL63 and 229E cause cold-like symptoms and are related to SARS-CoV-2, but their natural histories are poorly understood. In a cohort of children followed from birth to 4 years, we documented all ... ...

Abstract	Background: The endemic coronaviruses OC43, HKU1, NL63 and 229E cause cold-like symptoms and are related to SARS-CoV-2, but their natural histories are poorly understood. In a cohort of children followed from birth to 4 years, we documented all coronavirus infections, including SARS-CoV-2, to understand protection against subsequent infections with the same virus (homotypic immunity) or a different coronavirus (heterotypic immunity). Methods: Mother-child pairs were enrolled in metropolitan Cincinnati during the third trimester of pregnancy in 2017-18. Mothers reported their child's socio-demographics, risk factors, and weekly symptoms. Mid-turbinate nasal swabs were collected weekly. Blood was collected at 6 weeks, 6, 12, 18, 24 months and annually thereafter. Infections were detected by testing nasal swabs by an RT-PCR multi-pathogen panel and by serum IgG responses. Health care visits were documented from pediatric records. Analysis was limited to 116 children with high sample adherence. Re-consent for monitoring SARS-CoV-2 infections from June 2020 through November 2021 was obtained for 74 (64%) children. Results: We detected 345 endemic coronavirus infections (1.1 infections/child-year) and 21 SARS-CoV-2 infections (0.3 infections/child-year). Endemic coronavirus and SARS-CoV-2 infections were asymptomatic or mild. Significant protective homotypic immunity occurred after a single infection with OC43 (77%) and HKU1 (84%), and after two infections with NL63 (73%). No heterotypic protection against endemic coronaviruses or SARS-CoV-2 was identified. Conclusions: Natural coronavirus infections were common and resulted in strong homotypic immunity but not heterotypic immunity against other coronaviruses, including SARS-CoV-2. Endemic coronavirus and SARS-CoV-2 infections in this US cohort were typically asymptomatic or mild.
Language	English
Publishing date	2024-03-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2668791-4
ISSN	2048-7207 ; 2048-7193
ISSN (online)	2048-7207
ISSN	2048-7193
DOI	10.1093/jpids/piae016
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