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Article ; Online: Optomechanical realization of the bosonic Kitaev chain.

Slim, Jesse J / Wanjura, Clara C / Brunelli, Matteo / Del Pino, Javier / Nunnenkamp, Andreas / Verhagen, Ewold

2024 Volume 627, Issue 8005, Page(s) 767–771

Abstract: The fermionic Kitaev chain is a canonical model featuring topological Majorana zero ... ...

Abstract	The fermionic Kitaev chain is a canonical model featuring topological Majorana zero modes
Language	English
Publishing date	2024-03-27
Publishing country	England
Document type	Journal Article
ZDB-ID	120714-3
ISSN	1476-4687 ; 0028-0836
ISSN (online)	1476-4687
ISSN	0028-0836
DOI	10.1038/s41586-024-07174-w
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Article ; Online: WHO 2022 Classification of Kidney Tumors: what is relevant? An update and future novelties for the pathologist.

Caliò, Anna / Marletta, Stefano / Brunelli, Matteo / Martignoni, Guido

Pathologica

2023 Volume 115, Issue 1, Page(s) 23–31

Abstract: Classification systems reflect our technical abilities in the investigation of tumors and our current theories on tumor development. Herein, by providing a historical perspective on the evolution of classifying renal tumors, we assess the current WHO ... ...

Abstract	Classification systems reflect our technical abilities in the investigation of tumors and our current theories on tumor development. Herein, by providing a historical perspective on the evolution of classifying renal tumors, we assess the current WHO classification highlighting the novelties and the implications of these changes in daily clinical practice.
MeSH term(s)	Humans ; Pathologists ; World Health Organization ; Kidney Neoplasms/diagnosis ; Kidney Neoplasms/pathology ; Carcinoma, Renal Cell/pathology
Language	English
Publishing date	2023-01-16
Publishing country	Italy
Document type	Journal Article ; Review
ZDB-ID	418229-7
ISSN	1591-951X ; 0031-2983
ISSN (online)	1591-951X
ISSN	0031-2983
DOI	10.32074/1591-951X-814
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Article ; Online: Nonreciprocal Dicke Model.

Chiacchio, Ezequiel I Rodríguez / Nunnenkamp, Andreas / Brunelli, Matteo

Physical review letters

2023 Volume 131, Issue 11, Page(s) 113602

Abstract: We investigate the physics of an open two-component Dicke model, where the light field mediates nonreciprocal interactions between two spin species. We show that the model, which we dub nonreciprocal Dicke model, exhibits a discrete parity-time (PT) ... ...

Abstract	We investigate the physics of an open two-component Dicke model, where the light field mediates nonreciprocal interactions between two spin species. We show that the model, which we dub nonreciprocal Dicke model, exhibits a discrete parity-time (PT) symmetry and we characterize the emergence of a nonstationary phase, so far explained in terms of dissipation-induced instability, as spontaneous breaking of PT symmetry. We further show that such PT symmetry breaking embodies an instance of a nonreciprocal phase transition, a concept recently introduced by Fruchart et al. [Nature (London) 592, 363 (2021)NATUAS0028-083610.1038/s41586-021-03375-9]. Remarkably, the phase transition in our model does not necessitate the presence of any underlying broken symmetry or exceptional points in the spectrum, both believed to be essential requirements for nonreciprocal phase transitions. Our results establish driven-dissipative light-matter systems as a new avenue for exploring nonreciprocal phase transitions and contribute to the theory of nonreciprocal collective phenomena.
Language	English
Publishing date	2023-09-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.131.113602
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Article ; Online: Response to Letter to the Editor: "Remote Placental Sign-Out: What Digital Pathology Can Offer for Pediatric Pathologists".

Marletta, Stefano / Pantanowitz, Liron / Santonicco, Nicola / Caputo, Alessandro / Bragantini, Emma / Brunelli, Matteo / Girolami, Ilaria / Eccher, Albino

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society

2024 , Page(s) 10935266231225791

Language	English
Publishing date	2024-03-11
Publishing country	United States
Document type	Letter
ZDB-ID	1463498-3
ISSN	1615-5742 ; 1093-5266
ISSN (online)	1615-5742
ISSN	1093-5266
DOI	10.1177/10935266231225791
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Article ; Online: Clinico-pathological implications of the 2022 WHO Renal Cell Carcinoma classification.

Rizzo, Mimma / Caliò, Anna / Brunelli, Matteo / Pezzicoli, Gaetano / Ganini, Carlo / Martignoni, Guido / Camillo, Porta

Cancer treatment reviews

2023 Volume 116, Page(s) 102558

Abstract: The new WHO classification of urogenital tumours published in 2022, contains significant revisions upon the previous 2016 version regarding Renal Cell Carcinoma (RCC). While the most common histotype remains almost untouched, some of the main novelties ... ...

Abstract	The new WHO classification of urogenital tumours published in 2022, contains significant revisions upon the previous 2016 version regarding Renal Cell Carcinoma (RCC). While the most common histotype remains almost untouched, some of the main novelties concerns papillary RCC and oncocytic neoplasms. The main change is the introduction of a new category of molecularly-defined RCC, which includes TFE3-rearranged RCC, TFEB-rearranged, and TFEB-amplified RCC, FH-deficient RCC, SDH-deficient RCC, ALK-rearranged RCC, ELOC (formerly TCEB1)-mutated RCC, SMARCB1 (INI1)-deficient RCC. In this paper we analyze the current knowledge on emerging entities and molecularly-defined RCC to assess whether the current pathological classification offers the oncologist the possibility of selecting more specific and personalized treatments, from both those currently available, as well as those that will soon be available.
MeSH term(s)	Humans ; Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/pathology ; Kidney Neoplasms/genetics ; Kidney Neoplasms/pathology ; World Health Organization
Language	English
Publishing date	2023-04-09
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	125102-8
ISSN	1532-1967 ; 0305-7372
ISSN (online)	1532-1967
ISSN	0305-7372
DOI	10.1016/j.ctrv.2023.102558
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Article ; Online: Report of two primary renal tumors with myxoid features. Differential diagnosis between benign and malignant entities.

Fioravanzo, Adele / Martignoni, Guido / Brunelli, Matteo / Segala, Diego / Erdini, Francesco

Pathologica

2022 Volume 113, Issue 6, Page(s) 427–435

Abstract: Renal mesenchymal neoplasms are rare entities which can have a benign or a malignant behavior. Herein we describe two renal mesenchymal tumors with myxoid stroma, investigating the wide spectrum of differential diagnosis. With our first case we ... ...

Abstract	Renal mesenchymal neoplasms are rare entities which can have a benign or a malignant behavior. Herein we describe two renal mesenchymal tumors with myxoid stroma, investigating the wide spectrum of differential diagnosis. With our first case we considered some benign entities such as myxoma, myxoid leiomyoma, and mixed epithelial and stromal tumor; with our second case we considered some sarcomas with myxoid features such as myxofibrosarcoma, low-grade fibromyxoid sarcoma, dedifferentiated liposarcoma, and myxoid liposarcoma. During the diagnostic process, it is important to integrate histopathological, immunohistochemical, and molecular data in order to avoid misdiagnosis. We concluded our second case report was a myxofibrosarcoma grade 1. To the best of our knowledge, we described the fourth primary renal myxofibrosarcoma reported in literature.
MeSH term(s)	Adult ; Diagnosis, Differential ; Humans ; Kidney Neoplasms/diagnostic imaging ; Kidney Neoplasms/surgery ; Liposarcoma, Myxoid/diagnostic imaging ; Neoplasms, Connective and Soft Tissue ; Soft Tissue Neoplasms/diagnosis
Language	English
Publishing date	2022-01-01
Publishing country	Italy
Document type	Case Reports
ZDB-ID	418229-7
ISSN	1591-951X ; 0031-2983
ISSN (online)	1591-951X
ISSN	0031-2983
DOI	10.32074/1591-951X-180
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Article ; Online: Immune checkpoint inhibitors in non-conventional histologies of renal-cell carcinoma.

Bersanelli, Melissa / Rebuzzi, Sara Elena / Roviello, Giandomenico / Catalano, Martina / Brunelli, Matteo / Rizzo, Mimma

Human vaccines & immunotherapeutics

2023 Volume 19, Issue 1, Page(s) 2171672

Abstract: For years, prospective randomized clinical trials excluded patients with non-conventional histologies of renal cell carcinoma (RCC). The paucity of data has led to adopting the same treatment strategies used for clear-cell RCC (ccRCC). In the present ... ...

Abstract	For years, prospective randomized clinical trials excluded patients with non-conventional histologies of renal cell carcinoma (RCC). The paucity of data has led to adopting the same treatment strategies used for clear-cell RCC (ccRCC). In the present narrative review, we explored state of the art about use of immune checkpoint inhibitors (ICIs) in variant histologies of RCC. According to the results collected, ICIs as monotherapy showed promising antitumor activity in advanced non-clear cell (ncc)RCC. The objective response rate (ORR) was similar to that observed with single-agent anti-PD-1 in the ccRCC population, either in the first-line or the second-line setting, and responder patients experienced an early and durable benefit. Combined ICI-based strategies have shown increasing evidence in nccRCC and robust results in the sarcomatoid variants of RCC. A definitive recommendation about treating non-conventional histologies, either in adjuvant or metastatic settings, should be supported by more extensive dedicated trials.
MeSH term(s)	Humans ; Carcinoma, Renal Cell/drug therapy ; Kidney Neoplasms/drug therapy ; Immune Checkpoint Inhibitors/therapeutic use ; Antineoplastic Agents/therapeutic use ; Prospective Studies
Chemical Substances	Immune Checkpoint Inhibitors ; Antineoplastic Agents
Language	English
Publishing date	2023-02-09
Publishing country	United States
Document type	Review ; Journal Article
ZDB-ID	2664176-8
ISSN	2164-554X ; 2164-5515
ISSN (online)	2164-554X
ISSN	2164-5515
DOI	10.1080/21645515.2023.2171672
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Article ; Online: Secretory carcinoma of salivary glands with NTRK3 break-apart molecular rearrangement: Potential misdiagnosis with mucoepidermoid carcinoma.

Nocini, Riccardo / Sanna, Giangiacomo / Trotolo, Alessandro / Fior, Andrea / Brunelli, Matteo / Manfrin, Erminia / Favero, Vittorio

Journal of stomatology, oral and maxillofacial surgery

2023 Volume 124, Issue 6S, Page(s) 101635

Abstract: A woman presented a right submandibular gland lesion with cytologic diagnosis of mucoepidermoid carcinoma. Patient underwent sialoadenectomy en bloc with supraomohyoid neck dissection. Positivity for ETV6-NTRK3 genes fusion on surgical sample led to ... ...

Abstract	A woman presented a right submandibular gland lesion with cytologic diagnosis of mucoepidermoid carcinoma. Patient underwent sialoadenectomy en bloc with supraomohyoid neck dissection. Positivity for ETV6-NTRK3 genes fusion on surgical sample led to final diagnosis of secretory carcinoma (SC). Secretory carcinoma has been renamed by WHO in 2017 from mammary-analogue-secretory carcinoma (MASC). Only 649 have been reported until 2019. While cytologic alteration are shared with other neoplasms as the acinic cell and mucoepidermoid carcinomas, ETV6-NTRK3 rearrangement is pathognomonic of SC. Although usually indolent and with low-stage presentation, SC has higher rate of local recurrences and nodal involvement than ACC. Surgical treatment represent the gold standard. Real prevalence of SC is probably underestimated due to the recent WHO 2017 reclassification. While cytologic analysis does not allow to discriminate SC from other malignancies, chromosomal examination is recommended. When low-grade SC is diagnosed, complete surgical resection assures good prognosis.
MeSH term(s)	Female ; Humans ; Carcinoma, Mucoepidermoid/diagnosis ; Carcinoma, Mucoepidermoid/genetics ; Carcinoma, Mucoepidermoid/surgery ; Salivary Gland Neoplasms/diagnosis ; Salivary Gland Neoplasms/genetics ; Salivary Gland Neoplasms/surgery ; Oncogene Proteins, Fusion/genetics ; Immunohistochemistry ; Salivary Glands/pathology ; Carcinoma ; Diagnostic Errors
Chemical Substances	Oncogene Proteins, Fusion
Language	English
Publishing date	2023-09-12
Publishing country	France
Document type	Case Reports
ZDB-ID	2916276-2
ISSN	2468-7855 ; 2468-8509
ISSN (online)	2468-7855
ISSN	2468-8509
DOI	10.1016/j.jormas.2023.101635
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Article ; Online: Correspondence between Non-Hermitian Topology and Directional Amplification in the Presence of Disorder.

Wanjura, Clara C / Brunelli, Matteo / Nunnenkamp, Andreas

Physical review letters

2021 Volume 127, Issue 21, Page(s) 213601

Abstract: In order for non-Hermitian (NH) topological effects to be relevant for practical applications, it is necessary to study disordered systems. Without disorder, a class of driven-dissipative cavity arrays displays directional amplification when associated ... ...

Abstract	In order for non-Hermitian (NH) topological effects to be relevant for practical applications, it is necessary to study disordered systems. Without disorder, a class of driven-dissipative cavity arrays displays directional amplification when associated with a nontrivial winding number of the NH dynamic matrix. In this work, we show analytically that the correspondence between NH topology and directional amplification holds also in the presence of disorder. We first show that a NH topological phase is preserved as long as the size of the point gap, i.e., the minimum distance of the disorderless complex spectrum from the origin, is larger than the maximum amount of disorder; the disorder is assumed to be bounded but otherwise general, i.e., complex and both local (on-site disorder) and nonlocal (disordered couplings). We then derive analytic bounds for the probability distribution of the scattering matrix elements, which show that the key features of nontrivial NH topology, namely, that the end-to-end forward (reverse) gain grows (is suppressed) exponentially with system size, are preserved in disordered systems. Our results prove that NH topology in cavity arrays is robust against disorder.
Language	English
Publishing date	2021-12-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.127.213601
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Article: On the conjoint estimation of inconsistency and intransitivity of pairwise comparisons

Brunelli, Matteo

Operations research letters Vol. 44, No. 5 , p. 672-675

2016 Volume 44, Issue 5, Page(s) 672–675

Author's details	Matteo Brunelli
Keywords	Pairwise comparisons ; Preference relations ; Consistency ; Transitivity ; Inconsistency index
Language	English
Publisher	Elsevier
Publishing place	Amsterdam [u.a.]
Document type	Article
ZDB-ID	720735-9
ISSN	0167-6377
Database	ECONomics Information System

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